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Registros recuperados : 15 | |
1. | | TSURUTA, S.; MISZTAL, I.; AGUILAR, I.; LAWLOR, T. J. Genome wide association study on cow mortality in three US regions. Volume Species Breeding: Dairy cattle (Posters), 805. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.805.Biblioteca(s): INIA Las Brujas. |
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2. | | TSURUTA, S.; MISZTAL, I.; AGUILAR, I.; LAWLOR, T.J. Multiple-trait genomic evaluation of linear type traits using genomic and phenotypic data in US Holsteins. Journal of Dairy Science, 2011, v.94, no.8, p.4198-4204. OPEN ACCESS. Article history: Received February 9, 2011. / Accepted April 8, 2011.Biblioteca(s): INIA Las Brujas. |
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4. | | LOURENCO, D; MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LAWLOR, T. J.; WELLER, J. I. Are evaluations on young genotyped dairy bulls benefiting from the past generations? [conference paper]. Volume Species Breeding: Dairy cattle, 297. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.297.Biblioteca(s): INIA Las Brujas. |
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5. | | AGUILAR, I.; MISZTAL, I.; JOHNSON, D.L.; LEGARRA, A.; TSURUTA, S.; LAWLOR, T.J. Hot topic: A unified approach to utilize phenotypic, full pedigree, and genomic information for genetic evaluation of Holstein final score. Journal of Dairy Science, 2010, v. 93, no. 2, p. 743-752. OPEN ACCESS Article history: Received September 14, 2009 / Accepted November 10, 2009 / Published in issue: February 2010.Biblioteca(s): INIA Las Brujas. |
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6. | | TSURUTA, S.; AGUILAR, I.; MISZTAL, I.; LEGARRA, A.; LAWLOR, T. J. Multiple trait genetic evaluation of linear type traits using genomic and phenotypic data in US Holsteins. Volume Genetic improvement programmes: Selection using molecular information - Poster Sessions, 0489. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0489.Biblioteca(s): INIA Las Brujas. |
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8. | | MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LEGARRA, A.; VAN RADEN, P.M.; LAWLOR, T.J. Methods to approximate reliabilities in single-step genomic evaluation. Journal of Dairy Science, 2013, v.96, no.1, p.647-654. OPEN ACCESS. Article history: Received April 24, 2012. / Accepted September 18, 2012.Biblioteca(s): INIA Las Brujas. |
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9. | | MISZTAL, I.; AGUILAR, I.; LEGARRA, A.; JOHNSON, D.; TSURUTA, S.; LAWLOR, T. J. A unified approach to utilize phenotypic, full pedigree, and genomic information for genetic evaluation. Volume Methods and tools: Software and bioinformatics - Lecture Sessions, 0050. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0050. Acknowledgements: This study was partially funded by the Holstein Association, Smithfield Premium Genetics, and AFRI grants 2009-65205-05665 and 2010-65205-20366 from the USDA NIFA Animal Genome Program.Biblioteca(s): INIA Las Brujas. |
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10. | | AGUILAR, I.; MISZTAL, I.; JOHNSON, D. L.; LEGARRA, A.; TSURUTA, S.; LAWLOR, T. J. Uso de información genómica en evaluaciones genéticas. Agrociencia Uruguay, 2010, v. 14, no. 3, p. 43-47. Agrociencia, Nro especial: Congreso Asociación Uruguaya de Producción Animal, 3., 4-5 Noviembre 2010, Montevideo, UY: INIA, Facultad de Agronomía, SMVU.Biblioteca(s): INIA Las Brujas. |
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11. | | LOURENCO, D.A.L.; MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LAWLOR, T.J.; FORNI, S.; WELLER, J.I. Are evaluations on young genotyped animals benefiting from the past generations?. Journal of Dairy Science, 2014, v.97, no.6, p.3930-3942. OPEN ACCESS Article history: Received November 26, 2013. // Accepted February 11, 2014. OPEN ACCESSBiblioteca(s): INIA Las Brujas. |
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12. | | MISZTAL, I.; FRAGOMENI, B.; LOURENÇO, D. A. L.; TSURUTA, S.; MASUDA, Y.; AGUILAR, I.; LEGARRA, A.; LAWLOR, T. J. Efficient inversion of genomic relationship matrix by the Algorithm for Proven and Young (APY). Interbull Bulletin, 2015, v. 49, p. 111-116.Biblioteca(s): INIA Las Brujas. |
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13. | | FRAGOMENI, B.O.; LOURENCO, D.A.L.; TSURUTA, S.; MASUDA, Y.; AGUILAR, I.; LEGARRA, A.; LAWLOR, T.J.; MIZTAL, I. Hot topic: Use of genomic recursions in single-step genomic best linear unbiased predictor (BLUP) with a large number of genotypes. Journal of Dairy Science, 2015, v.98, no.6, p.4090-4094. OPEN ACCESS. Article history: Received November 18, 2014 / Accepted March 13, 2015 / Published online: April 8, 2015.Biblioteca(s): INIA Las Brujas. |
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14. | | MASUDA, Y.; MISZTAL, I.; TSURUTA, S.; LEGARRA, A.; AGUILAR, I.; LOURENCO, D.A.L.; FRAGOMENI, B.O.; LAWLOR, T.J. Implementation of genomic recursions in single-step genomic best linear unbiased predictor for US Holsteins with a large number of genotyped animals. Journal of Dairy Science, 2016, v.99, no.3, p.1968-1974. OPEN ACCESS OPEN ACCESS. Received 19 October 2015, Accepted 1 December 2015, Available online 21 January 2016Biblioteca(s): INIA Las Brujas. |
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15. | | MASUDA, Y.; MISZTAL, I.; TSURUTA, S.; LOURENÇO, D. A. L.; FRAGOMENI, B.; LEGARRA, A.; AGUILAR, I.; LAWLOR, T. J. Single-step genomic evaluations with 570K genotyped animals in US Holsteins. Interbull Bulletin, 2015, v. 49, p. 85-89.Biblioteca(s): INIA Las Brujas. |
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Registros recuperados : 15 | |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
21/02/2014 |
Actualizado : |
23/10/2019 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
A - 1 |
Autor : |
TSURUTA, S.; MISZTAL, I.; AGUILAR, I.; LAWLOR, T.J. |
Afiliación : |
IGNACIO AGUILAR GARCIA, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay. |
Título : |
Multiple-trait genomic evaluation of linear type traits using genomic and phenotypic data in US Holsteins. |
Fecha de publicación : |
2011 |
Fuente / Imprenta : |
Journal of Dairy Science, 2011, v.94, no.8, p.4198-4204. OPEN ACCESS. |
ISSN : |
0022-0302 |
DOI : |
10.3168/jds.2011-4256 |
Idioma : |
Inglés |
Notas : |
Article history: Received February 9, 2011. / Accepted April 8, 2011. |
Contenido : |
ABSTRACT.
Currently, the USDA uses a single-trait (ST) model with several intermediate steps to obtain genomic evaluations for US Holsteins. In this study, genomic evaluations for 18 linear type traits were obtained with a multiple-trait (MT) model using a unified single-step procedure. The phenotypic type data on up to 18 traits were available for 4,813,726 Holsteins, and single nucleotide polymorphism markers from the Illumina BovineSNP50 genotyping Beadchip (Illumina Inc., San Diego, CA) were available on 17,293 bulls. Genomic predictions were computed with several genomic relationship matrices (G) that assumed different allele frequencies: equal, base, current, and current scaled. Computations were carried out with ST and MT models. Procedures were compared by coefficients of determination (R 2) and regression of 2004 prediction of bulls with no daughters in 2004 on daughter deviations of those bulls in 2009. Predictions for 2004 also included parent averages without the use of genomic information. The R 2 for parent averages ranged from 10 to 34% for ST models and from 12 to 35% for MT models. The average R 2 for all G were 34 and 37% for ST and MT models, respectively. All of the regression coefficients were <1.0, indicating that estimated breeding values in 2009 of 1,307 genotyped young bulls' parents tended to be biased. The average regression coefficients ranged from 0.74 to 0.79 and from 0.75 to 0.80 for ST and MT models, respectively. When the weight for the inverse of the numerator relationship matrix (A -1) for genotyped animals was reduced from 1 to 0.7, R 2 remained almost identical while the regression coefficients increased by 0.11-0.26 and 0.12-0.23 for ST and MT models, respectively. The ST models required about 5s per iteration, whereas MT models required 3 (6) min per iteration for the regular (genomic) model. The MT single-step approach is feasible for 18 linear type traits in US Holstein cattle. Accuracy for genomic evaluation increases when switching ST models to MT models. Inflation of genomic evaluations for young bulls could be reduced by choosing a small weight for the A -1 for genotyped bulls.
© 2011 American Dairy Science Association. MenosABSTRACT.
Currently, the USDA uses a single-trait (ST) model with several intermediate steps to obtain genomic evaluations for US Holsteins. In this study, genomic evaluations for 18 linear type traits were obtained with a multiple-trait (MT) model using a unified single-step procedure. The phenotypic type data on up to 18 traits were available for 4,813,726 Holsteins, and single nucleotide polymorphism markers from the Illumina BovineSNP50 genotyping Beadchip (Illumina Inc., San Diego, CA) were available on 17,293 bulls. Genomic predictions were computed with several genomic relationship matrices (G) that assumed different allele frequencies: equal, base, current, and current scaled. Computations were carried out with ST and MT models. Procedures were compared by coefficients of determination (R 2) and regression of 2004 prediction of bulls with no daughters in 2004 on daughter deviations of those bulls in 2009. Predictions for 2004 also included parent averages without the use of genomic information. The R 2 for parent averages ranged from 10 to 34% for ST models and from 12 to 35% for MT models. The average R 2 for all G were 34 and 37% for ST and MT models, respectively. All of the regression coefficients were <1.0, indicating that estimated breeding values in 2009 of 1,307 genotyped young bulls' parents tended to be biased. The average regression coefficients ranged from 0.74 to 0.79 and from 0.75 to 0.80 for ST and MT models, respectively. When the weight for the i... Presentar Todo |
Thesagro : |
MEJORAMIENTO GENÉTICO ANIMAL. |
Asunto categoría : |
L10 Genética y mejoramiento animal |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/3507/1/Aguilar-I.-2011.-Jr.Dairy-Sc.-v.948-p.4198-4204.pdf
https://www.journalofdairyscience.org/article/S0022-0302(11)00423-1/pdf
|
Marc : |
LEADER 02915naa a2200205 a 4500 001 1012838 005 2019-10-23 008 2011 bl uuuu u00u1 u #d 022 $a0022-0302 024 7 $a10.3168/jds.2011-4256$2DOI 100 1 $aTSURUTA, S. 245 $aMultiple-trait genomic evaluation of linear type traits using genomic and phenotypic data in US Holsteins.$h[electronic resource] 260 $c2011 500 $aArticle history: Received February 9, 2011. / Accepted April 8, 2011. 520 $aABSTRACT. Currently, the USDA uses a single-trait (ST) model with several intermediate steps to obtain genomic evaluations for US Holsteins. In this study, genomic evaluations for 18 linear type traits were obtained with a multiple-trait (MT) model using a unified single-step procedure. The phenotypic type data on up to 18 traits were available for 4,813,726 Holsteins, and single nucleotide polymorphism markers from the Illumina BovineSNP50 genotyping Beadchip (Illumina Inc., San Diego, CA) were available on 17,293 bulls. Genomic predictions were computed with several genomic relationship matrices (G) that assumed different allele frequencies: equal, base, current, and current scaled. Computations were carried out with ST and MT models. Procedures were compared by coefficients of determination (R 2) and regression of 2004 prediction of bulls with no daughters in 2004 on daughter deviations of those bulls in 2009. Predictions for 2004 also included parent averages without the use of genomic information. The R 2 for parent averages ranged from 10 to 34% for ST models and from 12 to 35% for MT models. The average R 2 for all G were 34 and 37% for ST and MT models, respectively. All of the regression coefficients were <1.0, indicating that estimated breeding values in 2009 of 1,307 genotyped young bulls' parents tended to be biased. The average regression coefficients ranged from 0.74 to 0.79 and from 0.75 to 0.80 for ST and MT models, respectively. When the weight for the inverse of the numerator relationship matrix (A -1) for genotyped animals was reduced from 1 to 0.7, R 2 remained almost identical while the regression coefficients increased by 0.11-0.26 and 0.12-0.23 for ST and MT models, respectively. The ST models required about 5s per iteration, whereas MT models required 3 (6) min per iteration for the regular (genomic) model. The MT single-step approach is feasible for 18 linear type traits in US Holstein cattle. Accuracy for genomic evaluation increases when switching ST models to MT models. Inflation of genomic evaluations for young bulls could be reduced by choosing a small weight for the A -1 for genotyped bulls. © 2011 American Dairy Science Association. 650 $aMEJORAMIENTO GENÉTICO ANIMAL 700 1 $aMISZTAL, I. 700 1 $aAGUILAR, I. 700 1 $aLAWLOR, T.J. 773 $tJournal of Dairy Science, 2011$gv.94, no.8, p.4198-4204. OPEN ACCESS.
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