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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
31/03/2021 |
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Actualizado : |
31/03/2021 |
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Tipo de producción científica : |
Trabajos en Congresos/Conferencias |
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Autor : |
LOURENCO, D.; TSURUTA, S.; FRAGOMENI, B.; MASUDA, Y.; AGUILAR, I.; LEGARRA, A.; MILLER, S.; MOSER, D.; MISZTAL, I. |
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Afiliación : |
DANIELA LOURENCO, University of Georgia, Department of Animal and Dairy Science, GA, USA; SHOGO TSURUTA, University of Georgia, Department of Animal and Dairy Science, GA, USA; BRENO FRAGOMENI, University of Georgia, Department of Animal and Dairy Science, GA, USA; YUTAKA MASUDA, University of Georgia, Department of Animal and Dairy Science, GA, USA; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDRÉS LEGARRA, Institut National de la Recherche Agronomique, Castanet Tolosan, France; STEPHEN MILLER, Angus Genetics Inc., MO, USA; DAN MOSER, Angus Genetics Inc., MO, USA; IGNACY MISZTAL, University of Georgia, Department of Animal and Dairy Science, GA, USA. |
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Título : |
Single-step genomic BLUP for national beef cattle evaluation in US: from initial developments to final implementation. |
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Complemento del título : |
Volume Species - Bovine (beef) 1, 495. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018. |
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Idioma : |
Inglés |
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Contenido : |
ABSTRACT.
The objective of this study was to implement single-step genomic BLUP (ssGBLUP) for national Angus cattle evaluation in the US. National evaluations include a variety of models with several linear and categorical traits, maternal effects, multibreed data, and a large number of genotyped animals. For the initial investigation, we used a dataset from 2014 that comprised over 8 million animals, 6 million birth weight (BW) and weaning weight (WW) records, 3.4 million post-weaning gain (PWG) records, and genotypes for 52k animals. A dataset from 2017 was later used that included 335k genotyped animals. The ability to predict future performance of young animals was investigated when using regular BLUP and ssGBLUP. Because of the increasing number of genotyped animals and the high computing cost to invert the genomic relationship matrix (G), the algorithm for proven and young (APY) was used to approximate the inverse of G. The APY uses recursions on a small subset of genotyped animals, called core. We further tested the feasibility of having daily interim genomic predictions for newly-genotyped animals based on SNP effects derived from the previous official ssGBLUP evaluation. In addition, we extended all models used in traditional evaluations to ssGBLUP, and compared genetic trends from traditional BLUP, ssGBLUP, and a multistep method that was implemented for the American Angus genomic evaluation in 2009. A new algorithm to approximate accuracy of GEBV for large genomic data was also developed. On average, the increase in ability to predict future performance, for BW, WW, and PWG, with ssGBLUP was 25% in the 2014 data and 36% in the 2017 data, compared to the traditional BLUP. The ssGBLUP with APY was as accurate as the regular ssGBLUP when the number of core animals was at least 10,000, independently of which animals were in the core group. Interim predictions derived from ssGBLUP provided accurate genomic values for newly-genotyped animals. Genetic trends for ssGBLUP and BLUP were similar, revealing overestimation in multistep evaluations, especially for traits with less phenotypes. Single-step GBLUP became a reality for American Angus evaluation and its implementation process resulted in successful updates in methodology, making this approach mature for national beef cattle evaluation. Keywords: algorithm for proven and young, Angus, genomic selection, indirect prediction. MenosABSTRACT.
The objective of this study was to implement single-step genomic BLUP (ssGBLUP) for national Angus cattle evaluation in the US. National evaluations include a variety of models with several linear and categorical traits, maternal effects, multibreed data, and a large number of genotyped animals. For the initial investigation, we used a dataset from 2014 that comprised over 8 million animals, 6 million birth weight (BW) and weaning weight (WW) records, 3.4 million post-weaning gain (PWG) records, and genotypes for 52k animals. A dataset from 2017 was later used that included 335k genotyped animals. The ability to predict future performance of young animals was investigated when using regular BLUP and ssGBLUP. Because of the increasing number of genotyped animals and the high computing cost to invert the genomic relationship matrix (G), the algorithm for proven and young (APY) was used to approximate the inverse of G. The APY uses recursions on a small subset of genotyped animals, called core. We further tested the feasibility of having daily interim genomic predictions for newly-genotyped animals based on SNP effects derived from the previous official ssGBLUP evaluation. In addition, we extended all models used in traditional evaluations to ssGBLUP, and compared genetic trends from traditional BLUP, ssGBLUP, and a multistep method that was implemented for the American Angus genomic evaluation in 2009. A new algorithm to approximate accuracy of GEBV for large genomic... Presentar Todo |
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Palabras claves : |
Algorithm for proven and young; Angus; Genomic selection; Indirect prediction. |
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Asunto categoría : |
L01 Ganadería |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/15436/1/Lourenco-et-al-2018-WCGALP.pdf
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Marc : |
LEADER 03286nam a2200253 a 4500
001 1061912
005 2021-03-31
008 2018 bl uuuu u01u1 u #d
100 1 $aLOURENCO, D.
245 $aSingle-step genomic BLUP for national beef cattle evaluation in US$bfrom initial developments to final implementation.$h[electronic resource]
260 $aIn: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018.$c2018
520 $aABSTRACT. The objective of this study was to implement single-step genomic BLUP (ssGBLUP) for national Angus cattle evaluation in the US. National evaluations include a variety of models with several linear and categorical traits, maternal effects, multibreed data, and a large number of genotyped animals. For the initial investigation, we used a dataset from 2014 that comprised over 8 million animals, 6 million birth weight (BW) and weaning weight (WW) records, 3.4 million post-weaning gain (PWG) records, and genotypes for 52k animals. A dataset from 2017 was later used that included 335k genotyped animals. The ability to predict future performance of young animals was investigated when using regular BLUP and ssGBLUP. Because of the increasing number of genotyped animals and the high computing cost to invert the genomic relationship matrix (G), the algorithm for proven and young (APY) was used to approximate the inverse of G. The APY uses recursions on a small subset of genotyped animals, called core. We further tested the feasibility of having daily interim genomic predictions for newly-genotyped animals based on SNP effects derived from the previous official ssGBLUP evaluation. In addition, we extended all models used in traditional evaluations to ssGBLUP, and compared genetic trends from traditional BLUP, ssGBLUP, and a multistep method that was implemented for the American Angus genomic evaluation in 2009. A new algorithm to approximate accuracy of GEBV for large genomic data was also developed. On average, the increase in ability to predict future performance, for BW, WW, and PWG, with ssGBLUP was 25% in the 2014 data and 36% in the 2017 data, compared to the traditional BLUP. The ssGBLUP with APY was as accurate as the regular ssGBLUP when the number of core animals was at least 10,000, independently of which animals were in the core group. Interim predictions derived from ssGBLUP provided accurate genomic values for newly-genotyped animals. Genetic trends for ssGBLUP and BLUP were similar, revealing overestimation in multistep evaluations, especially for traits with less phenotypes. Single-step GBLUP became a reality for American Angus evaluation and its implementation process resulted in successful updates in methodology, making this approach mature for national beef cattle evaluation. Keywords: algorithm for proven and young, Angus, genomic selection, indirect prediction.
653 $aAlgorithm for proven and young
653 $aAngus
653 $aGenomic selection
653 $aIndirect prediction
700 1 $aTSURUTA, S.
700 1 $aFRAGOMENI, B.
700 1 $aMASUDA, Y.
700 1 $aAGUILAR, I.
700 1 $aLEGARRA, A.
700 1 $aMILLER, S.
700 1 $aMOSER, D.
700 1 $aMISZTAL, I.
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Registro original : |
INIA Las Brujas (LB) |
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| Registros recuperados : 45 | |
| 21. |  | TSURUTA, S.; AGUILAR, I.; MISZTAL, I.; LEGARRA, A.; LAWLOR, T. J. Multiple trait genetic evaluation of linear type traits using genomic and phenotypic data in US Holsteins. Volume Genetic improvement programmes: Selection using molecular information - Poster Sessions, 0489. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0489.| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| 23. | | LOURENCO, D.; TSURUTA, S.; AGUILAR, I.; MASUDA, Y.; BERMANN, M.; LEGARRA, A.; MISZTAL, I. Recent updates in the BLUPF90 software suite. [366]. Part 19 - Methods and tools: software and computing strategies. In: Proceedings of the World Congress on Genetics Applied to Livestock Production (WCGALP), 12., Rotterdam, the Netherlands, 3-8 July 2022. doi: https://doi.org/10.3920/978-90-8686-940-4_366 1530-1533. Article history: Published online: February 9, 2023. -- Corresponding author: D. Lourenco, email: danilino@uga.edu| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| 24. | | LOURENCO, D.; LEGARRA, A.; TSURUTA, S.; MASUDA, Y.; AGUILAR, I.; MISZTAL, I. Single-step genomic evaluations from theory to practice: using snp chips and sequence data in blupf90. Genes, July 2020. Volume 11, Issue 7, Article number 790, Pages 1-32. Open Access. Doi: https://doi.org/10.3390/genes11070790 Article history: Received: 19 June 2020 / Revised: 3 July 2020 / Accepted: 6 July 2020 / Published: 14 July 2020.
(This article belongs to the Special Issue Genomic Prediction Methods for Sequencing Data):...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 25. | | LOURENCO, D.A.L.; MISZTAL, I.; WANG, H.; AGUILAR, I.; TSURUTA, S.; BERTRAND, J.K. Prediction accuracy for a simulated maternally affected trait of beef cattle using different genomic evaluation models. Journal of Animal Science, 2013, v.91, no.9, p.4090-4098. Article history: Published online July 26, 2013.
This study was partially funded by the American Angus Association (St. Joseph, MO) and the USDA Agriculture and Food Research Initiative (Grant no. 2009-65205-05665 from the USDA National...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 2 |
| Biblioteca(s): INIA Las Brujas. |
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| 26. | | MISZTAL, I.; AGUILAR, I.; TSURUTA, S.; SÁNCHEZ, J.P.; ZUMBACH, B. Studies on heat stress in dairy cattle and pigs. Volume Special topics: Animal breeding and the environmental challenges - Lecture Sessions, 0625. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0625.| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| 27. | | GARCÍA, A.; AGUILAR, I.; LEGARRA, A.; TSURUTA, S.; MISZTAL, I.; LOURENCO, D. Theoretical accuracy for indirect predictions based on SNP effects from single-step GBLUP. Genetics, Selection, Evolution : GSE, 2022, Volume 54, Issue 1, Pages 66. OPEN ACCESS. doi: https://doi.org/10.1186/s12711-022-00752-4 Article history: Received 22 March 2022; Accepted 23 August 2022; Published 27 September 2022.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - 1 |
| Biblioteca(s): INIA Las Brujas. |
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| 28. | | MISZTAL, I.; AGUILAR, I.; LEGARRA, A.; JOHNSON, D.; TSURUTA, S.; LAWLOR, T. J. A unified approach to utilize phenotypic, full pedigree, and genomic information for genetic evaluation. Volume Methods and tools: Software and bioinformatics - Lecture Sessions, 0050. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0050. Acknowledgements: This study was partially funded by the Holstein Association, Smithfield Premium Genetics, and AFRI grants 2009-65205-05665 and 2010-65205-20366 from the USDA NIFA Animal Genome Program.| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| 29. | | FRAGOMENI, B.O.; LOURENCO, D.A.L.; TSURUTA, S.; MASUDA, Y.; AGUILAR, I.; MISZTAL, I. Use of genomic recursions and algorithm for proven and young animals for single-step genomic BLUP analyses - a simulation study. Journal of Animal Breeding and Genetics, 2015, v.132, no.5, p. 340-345.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 30. | | AGUILAR, I.; MISZTAL, I.; JOHNSON, D. L.; LEGARRA, A.; TSURUTA, S.; LAWLOR, T. J. Uso de información genómica en evaluaciones genéticas. Agrociencia Uruguay, 2010, v. 14, no. 3, p. 43-47. Agrociencia, Nro especial: Congreso Asociación Uruguaya de Producción Animal, 3., 4-5 Noviembre 2010, Montevideo, UY: INIA, Facultad de Agronomía, SMVU.| Tipo: Artículos en Revistas Indexadas Nacionales | Circulación / Nivel : B - 5 |
| Biblioteca(s): INIA Las Brujas. |
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| 31. | | LOURENCO, D.A.L.; FRAGOMENI, B.O.; TSURUTA, S.; AGUILAR, I.; ZUMBACH, B.; HAWKEN, R.J.; LEGARRA, A.; MISZTAL, I. Accuracy of estimated breeding values with genomic information on males, females, or both: An example on broiler chicken. Genetics Selection Evolution, 2015, v. 242, p. 47-56. OPEN ACCESS. Article history: Received: 14 October 2014 / Accepted: 22 June 2015 / Published: 02 July 2015.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 32. | | LOURENCO, D.A.L.; MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LAWLOR, T.J.; FORNI, S.; WELLER, J.I. Are evaluations on young genotyped animals benefiting from the past generations?. Journal of Dairy Science, 2014, v.97, no.6, p.3930-3942. OPEN ACCESS Article history: Received November 26, 2013. // Accepted February 11, 2014. OPEN ACCESS| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 1 |
| Biblioteca(s): INIA Las Brujas. |
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| 33. | | CHEN, C. Y.; MISZTAL, I.; AGUILAR, I.; TSURUTA, S.; MEUWISSEN, T.; AGGREY, S. E.; MUIR, W. M. Genome wide marker assisted selection in chicken: making the most of all data, pedigree, phenotypic, and genomic in a simple one step procedure. Volume Genetic improvement programmes: Selection using molecular information - Lecture Sessions, 0288. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0288. Acknowledgements: The authors thank Cobb-Vantress for access to data for this study. This study was partially funded by the Holstein Association, Smithfield Premium Genetics, and by AFRI grants 2009-65205-05665 and 2010-65205-20366 from...| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| 34. | | MISZTAL, I.; FRAGOMENI, B.; LOURENÇO, D. A. L.; TSURUTA, S.; MASUDA, Y.; AGUILAR, I.; LEGARRA, A.; LAWLOR, T. J. Efficient inversion of genomic relationship matrix by the Algorithm for Proven and Young (APY). Interbull Bulletin, 2015, v. 49, p. 111-116.| Tipo: Artículos Indexados |
| Biblioteca(s): INIA Las Brujas. |
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| 35. | | MASUDA, Y.; MISZTAL, I.; TSURUTA, S.; LEGARRA, A.; AGUILAR, I.; LOURENCO, D.A.L.; FRAGOMENI, B.O.; LAWLOR, T.J. Implementation of genomic recursions in single-step genomic best linear unbiased predictor for US Holsteins with a large number of genotyped animals. Journal of Dairy Science, 2016, v.99, no.3, p.1968-1974. OPEN ACCESS OPEN ACCESS. Received 19 October 2015, Accepted 1 December 2015, Available online 21 January 2016| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 36. | | LOURENCO, D.A.L.; MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; EZRA, E.; RON, M.; SHIRAK, A.; WELLER, J.I. Methods for genomic evaluation of a relatively small genotyped dairy population and effect of genotyped cow information in multiparity analyses. Journal of Dairy Science, 2014, v.97, no.3, p.1742-1752. OPEN ACCESS. Article history: Received September 10, 2013. / Accepted December 6, 2013.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 1 |
| Biblioteca(s): INIA Las Brujas. |
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| 37. | | FRAGOMENI, B.O.; LOURENCO, D.A.L.; TSURUTA, S.; MASUDA, Y.; AGUILAR, I.; LEGARRA, A.; LAWLOR, T.J.; MIZTAL, I. Hot topic: Use of genomic recursions in single-step genomic best linear unbiased predictor (BLUP) with a large number of genotypes. Journal of Dairy Science, 2015, v.98, no.6, p.4090-4094. OPEN ACCESS. Article history: Received November 18, 2014 / Accepted March 13, 2015 / Published online: April 8, 2015.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 38. | | FORNERIS, N. S.; LEGARRA, A.; VITEZICA, Z. G.; TSURUTA, S.; AGUILAR, I.; MISZTAL, I.; CANTET, R. J. C. Quality control of genotypes using heritability estimates of gene content at the marker. Genetics, 2015, v. 199, p. 675-681. OPEN ACCESS. Manuscript received September 26, 2014; accepted for publication December 18, 2014; published Early Online January 6, 2015.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 39. | | FORNERIS, N. S.; LEGARRA, A.; VITEZICA, Z. G.; TSURUTA, S.; AGUILAR, I.; CANTET, R.J.C.; MISZTAL, I. Quality control of genotypes using heritability estimates of gene content. Volume Genetic Improvement Programs: Selection using molecular information (Posters), 471. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.471.| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| 40. | | LOURENCO, D.; TSURUTA, S.; FRAGOMENI, B.; MASUDA, Y.; AGUILAR, I.; LEGARRA, A.; MILLER, S.; MOSER, D.; MISZTAL, I. Single-step genomic BLUP for national beef cattle evaluation in US: from initial developments to final implementation. Volume Species - Bovine (beef) 1, 495. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018.| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| Registros recuperados : 45 | |
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