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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
21/02/2014 |
Actualizado : |
18/12/2018 |
Tipo de producción científica : |
Artículos Indexados |
Autor : |
MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LEGARRA, A.; LAWLOR, T. J. |
Afiliación : |
IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Approximation of genomic accuracies in single-step genomic evaluation. |
Fecha de publicación : |
2011 |
Fuente / Imprenta : |
Interbull Bulletin, 2011, v. 44, p. 103-109. |
Idioma : |
Inglés |
Contenido : |
ABSTRACT.
Reliability of predictions from single-step genomic BLUP (ssGBLUP) can be calculated by inversion, but that is not feasible for large data sets. Two proposed approximations of reliability are based on decomposition of a function of reliability into contributions from records, pedigree, and genotypes. The first approximation involves inversion of a matrix that contains inverses of the genomic relationship matrix (G) and the pedigree relationship matrix for genotyped animals (A22). The second approximation involves only the diagonal elements of those inverses. The approximations were tested with a simulated data set. The correlations between exact and approximated contributions due to genomic information were 0.92 for the first approximation and 0.56 for the second approximation; contributions were inflated 60 and 260%, respectively. The respective correlations for reliabilities were 0.98 and 0.72. After correction for inflation, those correlations increased to 0.99 and 0.89. Approximations of reliabilities of predictions by ssGBLUP are accurate and computationally feasible. A critical part of the approximations is quality control of SNP information and proper scaling of G. |
Palabras claves : |
ACCURACY; BLUP; GENOMIC PREDICTION; RELIABILITY; SINGLE-STEP EVALUATION. |
Asunto categoría : |
-- |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/12207/1/1199-2069-1-PB.pdf
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Marc : |
LEADER 01821naa a2200229 a 4500 001 1012454 005 2018-12-18 008 2011 bl uuuu u00u1 u #d 100 1 $aMISZTAL, I. 245 $aApproximation of genomic accuracies in single-step genomic evaluation.$h[electronic resource] 260 $c2011 520 $aABSTRACT. Reliability of predictions from single-step genomic BLUP (ssGBLUP) can be calculated by inversion, but that is not feasible for large data sets. Two proposed approximations of reliability are based on decomposition of a function of reliability into contributions from records, pedigree, and genotypes. The first approximation involves inversion of a matrix that contains inverses of the genomic relationship matrix (G) and the pedigree relationship matrix for genotyped animals (A22). The second approximation involves only the diagonal elements of those inverses. The approximations were tested with a simulated data set. The correlations between exact and approximated contributions due to genomic information were 0.92 for the first approximation and 0.56 for the second approximation; contributions were inflated 60 and 260%, respectively. The respective correlations for reliabilities were 0.98 and 0.72. After correction for inflation, those correlations increased to 0.99 and 0.89. Approximations of reliabilities of predictions by ssGBLUP are accurate and computationally feasible. A critical part of the approximations is quality control of SNP information and proper scaling of G. 653 $aACCURACY 653 $aBLUP 653 $aGENOMIC PREDICTION 653 $aRELIABILITY 653 $aSINGLE-STEP EVALUATION 700 1 $aTSURUTA, S. 700 1 $aAGUILAR, I. 700 1 $aLEGARRA, A. 700 1 $aLAWLOR, T. J. 773 $tInterbull Bulletin, 2011$gv. 44, p. 103-109.
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INIA Las Brujas (LB) |
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Registros recuperados : 218 | |
81. | | MASUDA, Y.; AGUILAR, I.; TSURUTA, S.; MISZTAL, I. Technical note: Acceleration of sparse operations for average-information REML analyses with supernodal methods and sparse-storage refinements. Journal of Animal Science, 2015, v. 93, p. 4670 - 4674. Published October 9, 2015 Article history: Received June 8, 2015.; Accepted August 7, 2015.
1. We acknowledge the work by François Guillaume in programming a hash function. We greatly appreciate the work of the two anonymous reviewers.
2. The AIREMLF90 program...Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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84. | | ZHANG, X.; LOURENCO, D.; MISZTAL, I.; AGUILAR, I.; LEGARRA, A. Weighted single-step genomic BLUP: an iterative approach for accurate calculation of GEBV and GWAS. Volume Methods and Tools: Statistical and genomic tools for mapping QTL and genes (Posters), 681. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.681.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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85. | | ZHANG, X.; LOURENCO, D.; AGUILAR, I.; LEGARRA, A.; MISZTAL, I. Weighting strategies for single-step genomic BLUP: An iterative approach for accurate calculation of GEBV and GWAS. Frontiers in Genetics, 19 August 2016, Volume 7, Issue AUG, Article number 151. OPEN ACCESS Article history: Received 15 May 2016 // Accepted 04 August 2016 // Published 19 August 2016.
Specialty section:
This article was submitted to Statistical Genetics and Methodology, a section of the journal Frontiers in Genetics.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 2 |
Biblioteca(s): INIA Las Brujas. |
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90. | | LEMA, O.M.; BRITO, G.; CLARIGET, J.; PEREZ, E.; RAVAGNOLO, O.; AGUILAR, I.; MONTOSSI, F. Dos años de evaluación de ganancia diaria invernal de terneros con paternidad conocida y su efecto sobre la recría
y terminación. In: CONGRESO ARGENTINO DE PRODUCCIÓN ANIMAL, 38., 2015. Resúmenes. Santa Rosa, La Pampa, AR: ASAS/AAPA, 2015 Revista Argentina de Producción Animal, 2015, v.35, Supl.1, p.62Tipo: Abstracts/Resúmenes |
Biblioteca(s): INIA La Estanzuela; INIA Treinta y Tres. |
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92. | | LOURENÇO, D. A. L.; MISZTAL, I.; TSURUTA, S.; FRAGOMENI, B.; AGUILAR, I.; MASUDA, Y.; MOSER, D. Direct and indirect genomic evaluations in beef cattle. Interbull Bulletin, 2015, v. 49, p.80 - 84.Tipo: Artículos Indexados |
Biblioteca(s): INIA Las Brujas. |
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94. | | LOURENCO, D; MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LAWLOR, T. J.; WELLER, J. I. Are evaluations on young genotyped dairy bulls benefiting from the past generations? [conference paper]. Volume Species Breeding: Dairy cattle, 297. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.297.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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97. | | NAVAJAS, E.; MACEDO, F.; LEMA, O.M.; LUZARDO, S.; AGUILAR, I. Accuracy of genomic predictions for carcass and meat quality traits in the Uruguayan Hereford breed. Volume Species - Bovine (beef) 1, p. 636. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018. 6 p. Acknowledgements: This work was supported by the Agencia Nacional de Investigación e Innovación (ANII) (grants RTS_1_2012_1_3489 and FMV_1_2011_1_6671), Instituto Nacional de Investigación Agropecuaria (INIA), Sociedad de Criadores de...Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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98. | | GARCÍA, A.; AGUILAR, I.; LEGARRA, A.; MILLER, S.; TSURUTA, S.; MISZTAL, I.; LOURENCO, D. Accuracy of indirect predictions for large datasets based on prediction error covariance of SNP effects from single-step GBLUP. [abstract 22]. Issue Section: Animal Breeding and Genetics. Journal of Animal Science, 2020, Volume 98, Issue Supplement 4, Pages 6-7. doi: https://doi.org/10.1093/jas/skaa278.012 Article history: 30 November 2020.
ASAS Annual 2020 Meeting Abstracts.Tipo: Abstracts/Resúmenes |
Biblioteca(s): INIA Las Brujas. |
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99. | | LEGARRA, A.; CHRISTENSEN, O. F.; VITEZICA, Z. G.; AGUILAR, I.; MISZTAL, I. Across-breeds ancestral relationships and metafounders for genomic evaluation. Volume Genetic Improvement Programs: Selection using molecular information, 075. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.075. Acknowledgements: This project has been financed by X-Gen and GenSSeq actions from SelGen metaprogram (INRA). We are grateful to the genotoul bioinformatics platform Toulouse Midi-Pyrenees for providing computing resources.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA Las Brujas. |
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100. | | LEMA, O.M.; AGUILAR, I.; DIONELLO, N.J.L.; CARDOSO, F.F.; RAVAGNOLO, O.; GIMENO, D. Additive, heterotic and recombination losses for direct and maternal effects in growth for British, Continental and Zebu crosses. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018.Tipo: Trabajos en Congresos/Conferencias |
Biblioteca(s): INIA La Estanzuela. |
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Registros recuperados : 218 | |
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