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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
09/09/2014 |
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Actualizado : |
23/10/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
LOURENCO, D.A.L.; MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; EZRA, E.; RON, M.; SHIRAK, A.; WELLER, J.I. |
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Afiliación : |
IGNACIO AGUILAR GARCIA, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay. |
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Título : |
Methods for genomic evaluation of a relatively small genotyped dairy population and effect of genotyped cow information in multiparity analyses. |
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Fecha de publicación : |
2014 |
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Fuente / Imprenta : |
Journal of Dairy Science, 2014, v.97, no.3, p.1742-1752. OPEN ACCESS. |
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ISSN : |
0022-0302 |
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DOI : |
10.3168/jds.2013-6916 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received September 10, 2013. / Accepted December 6, 2013. |
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Contenido : |
ABSTRACTS.
Methods for genomic prediction were evaluated for an Israeli Holstein dairy population of 713,686 cows and 1,305 progeny-tested bulls with genotypes. Inclusion of genotypes of 343 elite cows in an evaluation method that considers pedigree, phenotypes, and genotypes simultaneously was also evaluated. Two data sets were available: a complete data set with production records from 1985 through 2011, and a reduced data set with records after 2006 deleted. For each production trait, a multitrait animal model was used to compute traditional genetic evaluations for parities 1 through 3 as separate traits. Evaluations were calculated for the reduced and complete data sets. The evaluations from the reduced data set were used to calculate parent average for validation bulls, which was the benchmark for comparing gain in predictive ability from genomics. Genomic predictions for bulls in 2006 were calculated using a Bayesian regression method (BayesC), genomic BLUP (GBLUP), single-step GBLUP (ssGBLUP), and weighted ssGBLUP (WssGBLUP). Predictions using BayesC and GBLUP were calculated either with or without an index that included parent average. Genomic predictions that included elite cow genotypes were calculated using ssGBLUP and WssGBLUP. Predictive ability was assessed by coefficients of determination (R2) and regressions of predictions of 135 validation bulls with no daughters in 2006 on deregressed evaluations of those bulls in 2011. A reduction in R2 and regression coefficients was observed from parities 1 through 3. Fat and protein yields had the lowest R2 for all the methods. On average, R2 was lowest for parent averages, followed by GBLUP, BayesC, ssGBLUP, and WssGBLUP. For some traits, R2 for direct genomic values from BayesC and GBLUP were lower than those for parent averages. Genomic estimated breeding values using ssGBLUP were the least biased, and this method appears to be a suitable tool for genomic evaluation of a small genotyped population, as it automatically accounts for parental index, allows for inclusion of female genomic information without preadjustments in evaluations, and uses the same model as in traditional evaluations. Weighted ssGBLUP has the potential for higher evaluation accuracy.
© 2014 American Dairy Science Association. MenosABSTRACTS.
Methods for genomic prediction were evaluated for an Israeli Holstein dairy population of 713,686 cows and 1,305 progeny-tested bulls with genotypes. Inclusion of genotypes of 343 elite cows in an evaluation method that considers pedigree, phenotypes, and genotypes simultaneously was also evaluated. Two data sets were available: a complete data set with production records from 1985 through 2011, and a reduced data set with records after 2006 deleted. For each production trait, a multitrait animal model was used to compute traditional genetic evaluations for parities 1 through 3 as separate traits. Evaluations were calculated for the reduced and complete data sets. The evaluations from the reduced data set were used to calculate parent average for validation bulls, which was the benchmark for comparing gain in predictive ability from genomics. Genomic predictions for bulls in 2006 were calculated using a Bayesian regression method (BayesC), genomic BLUP (GBLUP), single-step GBLUP (ssGBLUP), and weighted ssGBLUP (WssGBLUP). Predictions using BayesC and GBLUP were calculated either with or without an index that included parent average. Genomic predictions that included elite cow genotypes were calculated using ssGBLUP and WssGBLUP. Predictive ability was assessed by coefficients of determination (R2) and regressions of predictions of 135 validation bulls with no daughters in 2006 on deregressed evaluations of those bulls in 2011. A reduction in R2 and regression coe... Presentar Todo |
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Thesagro : |
MEJORAMIENTO GENÉTICO ANIMAL; MODELOS MATEMÁTICOS; SELECCIÓN DE GENOTIPOS; SELECCIÓN GENÓMICA. |
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Asunto categoría : |
L10 Genética y mejoramiento animal |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/3043/1/Aguilar-I.-2014-Jr.Dairy-Sci.-v.973-p.1742-1752.pdf
https://www.journalofdairyscience.org/article/S0022-0302(14)00052-6/pdf
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Marc : |
LEADER 03270naa a2200289 a 4500
001 1050061
005 2019-10-23
008 2014 bl uuuu u00u1 u #d
022 $a0022-0302
024 7 $a10.3168/jds.2013-6916$2DOI
100 1 $aLOURENCO, D.A.L.
245 $aMethods for genomic evaluation of a relatively small genotyped dairy population and effect of genotyped cow information in multiparity analyses.$h[electronic resource]
260 $c2014
500 $aArticle history: Received September 10, 2013. / Accepted December 6, 2013.
520 $aABSTRACTS. Methods for genomic prediction were evaluated for an Israeli Holstein dairy population of 713,686 cows and 1,305 progeny-tested bulls with genotypes. Inclusion of genotypes of 343 elite cows in an evaluation method that considers pedigree, phenotypes, and genotypes simultaneously was also evaluated. Two data sets were available: a complete data set with production records from 1985 through 2011, and a reduced data set with records after 2006 deleted. For each production trait, a multitrait animal model was used to compute traditional genetic evaluations for parities 1 through 3 as separate traits. Evaluations were calculated for the reduced and complete data sets. The evaluations from the reduced data set were used to calculate parent average for validation bulls, which was the benchmark for comparing gain in predictive ability from genomics. Genomic predictions for bulls in 2006 were calculated using a Bayesian regression method (BayesC), genomic BLUP (GBLUP), single-step GBLUP (ssGBLUP), and weighted ssGBLUP (WssGBLUP). Predictions using BayesC and GBLUP were calculated either with or without an index that included parent average. Genomic predictions that included elite cow genotypes were calculated using ssGBLUP and WssGBLUP. Predictive ability was assessed by coefficients of determination (R2) and regressions of predictions of 135 validation bulls with no daughters in 2006 on deregressed evaluations of those bulls in 2011. A reduction in R2 and regression coefficients was observed from parities 1 through 3. Fat and protein yields had the lowest R2 for all the methods. On average, R2 was lowest for parent averages, followed by GBLUP, BayesC, ssGBLUP, and WssGBLUP. For some traits, R2 for direct genomic values from BayesC and GBLUP were lower than those for parent averages. Genomic estimated breeding values using ssGBLUP were the least biased, and this method appears to be a suitable tool for genomic evaluation of a small genotyped population, as it automatically accounts for parental index, allows for inclusion of female genomic information without preadjustments in evaluations, and uses the same model as in traditional evaluations. Weighted ssGBLUP has the potential for higher evaluation accuracy. © 2014 American Dairy Science Association.
650 $aMEJORAMIENTO GENÉTICO ANIMAL
650 $aMODELOS MATEMÁTICOS
650 $aSELECCIÓN DE GENOTIPOS
650 $aSELECCIÓN GENÓMICA
700 1 $aMISZTAL, I.
700 1 $aTSURUTA, S.
700 1 $aAGUILAR, I.
700 1 $aEZRA, E.
700 1 $aRON, M.
700 1 $aSHIRAK, A.
700 1 $aWELLER, J.I.
773 $tJournal of Dairy Science, 2014$gv.97, no.3, p.1742-1752. OPEN ACCESS.
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Registro original : |
INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
10/09/2014 |
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Actualizado : |
09/10/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
A - 1 |
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Autor : |
LOURENCO, D.A.L.; MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LAWLOR, T.J.; FORNI, S.; WELLER, J.I. |
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Afiliación : |
IGNACIO AGUILAR GARCIA, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay. |
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Título : |
Are evaluations on young genotyped animals benefiting from the past generations?. |
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Fecha de publicación : |
2014 |
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Fuente / Imprenta : |
Journal of Dairy Science, 2014, v.97, no.6, p.3930-3942. OPEN ACCESS |
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ISSN : |
0022-0302 |
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DOI : |
10.3168/jds.2013-7769 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received November 26, 2013. // Accepted February 11, 2014. OPEN ACCESS |
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Contenido : |
ABSTRACT.
Data sets of US Holsteins, Israeli Holsteins, and pigs from PIC (a Genus company, Hendersonville, TN) were used to evaluate the effect of different numbers of generations on ability to predict genomic breeding values of young genotyped animals. The influence of including only 2 generations of ancestors (A2) or all ancestors (Af) was also investigated. A total of 34,506 US Holsteins, 1,305 Israeli Holsteins, and 5,236 pigs were genotyped. The evaluations were computed by traditional BLUP and single-step genomic BLUP, and computing performance was assessed for the latter method. For the 2 Holstein data sets, coefficients of determination (R2) and regression (?) of deregressed evaluations from a full data set with records up to 2011 on estimated breeding values and genomic estimated breeding values from the truncated data sets were computed. The thresholds for data deletion were set by intervals of 5 yr, based on the average generation interval in dairy cattle. For the PIC data set, correlations between corrected phenotypes and estimated or genomic estimated breeding values were used to evaluate predictive ability on young animals born in 2010 and 2011. The reduced data set contained data up to 2009, and the thresholds were set based on an average generation interval of 3 yr. The number of generations that could be deleted without a reduction in accuracy depended on data structure and trait. For US Holsteins, removing 3 and 4 generations of data did not reduce accuracy of evaluations for final score in Af and A2 scenarios, respectively. For Israeli Holsteins, the accuracies for milk, fat, and protein yields were the highest when only phenotypes recorded in 2000 and later were included and full pedigrees were applied. Of the 135 Israeli bulls with genotypes (validation set) and daughter records only in the complete data set, 38 and 97 were sons of Israeli and foreign bulls, respectively. Although more phenotypic data increased the prediction accuracy for sons of Israeli bulls, the reverse was true for sons of foreign bulls. Also, more phenotypic data caused large inflation of genomic estimated breeding values for sons of foreign bulls, whereas the opposite was true with the deletion of all but the most recent phenotypic data. Results for protein and fat percentage were different from those for milk, fat, and protein yields; however, relatively, the changes in coefficients of determination and regression were smaller for percentage traits. For PIC data set, removing data from up to 5 generations did not erode predictive ability for genotyped animals for the 2 reproductive traits used in validation. Given the data used in this study, truncating old data reduces computation requirements but does not decrease the accuracy. For small populations that include local and imported animals, truncation may be beneficial for one group of animals and detrimental to another group. MenosABSTRACT.
Data sets of US Holsteins, Israeli Holsteins, and pigs from PIC (a Genus company, Hendersonville, TN) were used to evaluate the effect of different numbers of generations on ability to predict genomic breeding values of young genotyped animals. The influence of including only 2 generations of ancestors (A2) or all ancestors (Af) was also investigated. A total of 34,506 US Holsteins, 1,305 Israeli Holsteins, and 5,236 pigs were genotyped. The evaluations were computed by traditional BLUP and single-step genomic BLUP, and computing performance was assessed for the latter method. For the 2 Holstein data sets, coefficients of determination (R2) and regression (?) of deregressed evaluations from a full data set with records up to 2011 on estimated breeding values and genomic estimated breeding values from the truncated data sets were computed. The thresholds for data deletion were set by intervals of 5 yr, based on the average generation interval in dairy cattle. For the PIC data set, correlations between corrected phenotypes and estimated or genomic estimated breeding values were used to evaluate predictive ability on young animals born in 2010 and 2011. The reduced data set contained data up to 2009, and the thresholds were set based on an average generation interval of 3 yr. The number of generations that could be deleted without a reduction in accuracy depended on data structure and trait. For US Holsteins, removing 3 and 4 generations of data did not reduce accura... Presentar Todo |
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Palabras claves : |
DAIRY CATTLE; GENOMIC SELECTION; PEDIGREE DEPTH; SINGLE-STEP GENOMIC BLUP. |
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Thesagro : |
BLUP; GANADO DE LECHE; SELECCIÓN GENÓMICA. |
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Asunto categoría : |
L10 Genética y mejoramiento animal |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/3064/1/Aguilar-I.-2014-Jr.Dairy-Sci.-v.976-p.3930-3942.pdf
https://www.journalofdairyscience.org/article/S0022-0302(14)00225-2/pdf
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Marc : |
LEADER 03893naa a2200313 a 4500
001 1050114
005 2019-10-09
008 2014 bl uuuu u00u1 u #d
022 $a0022-0302
024 7 $a10.3168/jds.2013-7769$2DOI
100 1 $aLOURENCO, D.A.L.
245 $aAre evaluations on young genotyped animals benefiting from the past generations?.$h[electronic resource]
260 $c2014
500 $aArticle history: Received November 26, 2013. // Accepted February 11, 2014. OPEN ACCESS
520 $aABSTRACT. Data sets of US Holsteins, Israeli Holsteins, and pigs from PIC (a Genus company, Hendersonville, TN) were used to evaluate the effect of different numbers of generations on ability to predict genomic breeding values of young genotyped animals. The influence of including only 2 generations of ancestors (A2) or all ancestors (Af) was also investigated. A total of 34,506 US Holsteins, 1,305 Israeli Holsteins, and 5,236 pigs were genotyped. The evaluations were computed by traditional BLUP and single-step genomic BLUP, and computing performance was assessed for the latter method. For the 2 Holstein data sets, coefficients of determination (R2) and regression (?) of deregressed evaluations from a full data set with records up to 2011 on estimated breeding values and genomic estimated breeding values from the truncated data sets were computed. The thresholds for data deletion were set by intervals of 5 yr, based on the average generation interval in dairy cattle. For the PIC data set, correlations between corrected phenotypes and estimated or genomic estimated breeding values were used to evaluate predictive ability on young animals born in 2010 and 2011. The reduced data set contained data up to 2009, and the thresholds were set based on an average generation interval of 3 yr. The number of generations that could be deleted without a reduction in accuracy depended on data structure and trait. For US Holsteins, removing 3 and 4 generations of data did not reduce accuracy of evaluations for final score in Af and A2 scenarios, respectively. For Israeli Holsteins, the accuracies for milk, fat, and protein yields were the highest when only phenotypes recorded in 2000 and later were included and full pedigrees were applied. Of the 135 Israeli bulls with genotypes (validation set) and daughter records only in the complete data set, 38 and 97 were sons of Israeli and foreign bulls, respectively. Although more phenotypic data increased the prediction accuracy for sons of Israeli bulls, the reverse was true for sons of foreign bulls. Also, more phenotypic data caused large inflation of genomic estimated breeding values for sons of foreign bulls, whereas the opposite was true with the deletion of all but the most recent phenotypic data. Results for protein and fat percentage were different from those for milk, fat, and protein yields; however, relatively, the changes in coefficients of determination and regression were smaller for percentage traits. For PIC data set, removing data from up to 5 generations did not erode predictive ability for genotyped animals for the 2 reproductive traits used in validation. Given the data used in this study, truncating old data reduces computation requirements but does not decrease the accuracy. For small populations that include local and imported animals, truncation may be beneficial for one group of animals and detrimental to another group.
650 $aBLUP
650 $aGANADO DE LECHE
650 $aSELECCIÓN GENÓMICA
653 $aDAIRY CATTLE
653 $aGENOMIC SELECTION
653 $aPEDIGREE DEPTH
653 $aSINGLE-STEP GENOMIC BLUP
700 1 $aMISZTAL, I.
700 1 $aTSURUTA, S.
700 1 $aAGUILAR, I.
700 1 $aLAWLOR, T.J.
700 1 $aFORNI, S.
700 1 $aWELLER, J.I.
773 $tJournal of Dairy Science, 2014$gv.97, no.6, p.3930-3942. OPEN ACCESS
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