| |
|
|
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas. |
|
Fecha : |
31/07/2017 |
|
Actualizado : |
20/02/2019 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Autor : |
LADO, B.; BATTENFIELD, S. D.; GUZMÁN, C.; QUINCKE, M.; SINGH, R. P.; DREISIGACKER, S.; PEÑA, R. J.; FRITZ, AL.; SILVA, P.; POLAND, J.; GUTIÉRREZ, L. |
|
Afiliación : |
BETTINA LADO, Statistics Dep., Facultad de Agronomía, Univ. de la República, Montevideo, Uruguay; SARAH D. BATTENFIELD, Kansas State University, Department of Plant Pathology, Manhattan, United States; CARLOS GUZMÁN, Centro Internacional de Mejoramiento de Maiz y Trigo, Global Wheat Program, Mexico City, Mexico; MARTIN CONRADO QUINCKE WALDEN, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RAVI PRAKASH SINGH, Centro Internacional de Mejoramiento de Maiz y Trigo, Global Wheat Program, Mexico City, Mexico; SUSANNE DREISIGACKER, Centro Internacional de Mejoramiento de Maiz y Trigo, Applied Biotechnology Center, Mexico City, Mexico; ROBERTO JAVIER PEÑA, Centro Internacional de Mejoramiento de Maiz y Trigo, Global Wheat Program, Mexico City, Mexico; ALLAN K. FRITZ, Kansas State University, Manhattan, United States; MARIA PAULA SILVA VILLELLA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JESSE A. POLAND, Kansas State University, Department of Plant Pathology and Department of Agronomy, Manhattan, United States; LUCÍA GUTIÉRREZ, Kansas State University, Department of Plant Pathology and Department of Agronomy, Manhattan, United States. |
|
Título : |
Strategies for selecting crosses using genomic prediction in two wheat breeding programs. |
|
Fecha de publicación : |
2017 |
|
Fuente / Imprenta : |
The Plant Genome, 2017, v.10, Issue 2, 12p. OPEN ACCESS |
|
ISSN : |
1940-3372 |
|
DOI : |
10.3835/plantgenome2016.12.0128 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received: Dec 14, 2016 // Accepted: Mar 18, 2017 // Published: July 6, 2017.
B. Lado and S. Battenfield contributed equally.Assigned to Associate Editor Nicholas Tinker.
This is an open access article distributed under the CC BY-NC-ND license. |
|
Contenido : |
ABSTRACT.
The single most important decision in plant breeding programs is the selection of appropriate crosses. The ideal cross would provide superior predicted progeny performance and enough diversity to maintain genetic gain. The aim of this study was to compare the best crosses predicted using combinations of mid-parent value and variance prediction accounting for linkage disequilibrium (VLD) or assuming linkage equilibrium (VLE). After predicting the mean and the variance of each cross, we selected crosses based on mid-parent value, the top 10% of the progeny, and weighted mean and variance within progenies for grain yield, grain protein content, mixing time, and loaf volume in two applied wheat (Triticum aestivum L.) breeding programs: Instituto Nacional de Investigación Agropecuaria (INIA) Uruguay and CIMMYT Mexico. Although the variance of the progeny is important to increase the chances of finding superior individuals from transgressive segregation, we observed that the mid-parent values of the crosses drove the genetic gain but the variance of the progeny had a small impact on genetic gain for grain yield. However, the relative importance of the variance of the progeny was larger for quality traits. Overall, the genomic resources and the statistical models are now available to plant breeders to predict both the performance of breeding lines per se as well as the value of progeny from any potential crosses.
© Crop Science Society of America |
|
Palabras claves : |
GENOMIC SELECTION; WHEAT; WHEAT BREEDING PROGRAMS. |
|
Thesagro : |
TRIGO. |
|
Asunto categoría : |
-- |
|
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/12466/1/tpg-10-2-plantgenome2016.12.0128.pdf
https://dl.sciencesocieties.org/publications/tpg/articles/10/2/plantgenome2016.12.0128
|
|
Marc : |
LEADER 02631naa a2200325 a 4500
001 1057423
005 2019-02-20
008 2017 bl uuuu u00u1 u #d
022 $a1940-3372
024 7 $a10.3835/plantgenome2016.12.0128$2DOI
100 1 $aLADO, B.
245 $aStrategies for selecting crosses using genomic prediction in two wheat breeding programs.$h[electronic resource]
260 $c2017
500 $aArticle history: Received: Dec 14, 2016 // Accepted: Mar 18, 2017 // Published: July 6, 2017. B. Lado and S. Battenfield contributed equally.Assigned to Associate Editor Nicholas Tinker. This is an open access article distributed under the CC BY-NC-ND license.
520 $aABSTRACT. The single most important decision in plant breeding programs is the selection of appropriate crosses. The ideal cross would provide superior predicted progeny performance and enough diversity to maintain genetic gain. The aim of this study was to compare the best crosses predicted using combinations of mid-parent value and variance prediction accounting for linkage disequilibrium (VLD) or assuming linkage equilibrium (VLE). After predicting the mean and the variance of each cross, we selected crosses based on mid-parent value, the top 10% of the progeny, and weighted mean and variance within progenies for grain yield, grain protein content, mixing time, and loaf volume in two applied wheat (Triticum aestivum L.) breeding programs: Instituto Nacional de Investigación Agropecuaria (INIA) Uruguay and CIMMYT Mexico. Although the variance of the progeny is important to increase the chances of finding superior individuals from transgressive segregation, we observed that the mid-parent values of the crosses drove the genetic gain but the variance of the progeny had a small impact on genetic gain for grain yield. However, the relative importance of the variance of the progeny was larger for quality traits. Overall, the genomic resources and the statistical models are now available to plant breeders to predict both the performance of breeding lines per se as well as the value of progeny from any potential crosses. © Crop Science Society of America
650 $aTRIGO
653 $aGENOMIC SELECTION
653 $aWHEAT
653 $aWHEAT BREEDING PROGRAMS
700 1 $aBATTENFIELD, S. D.
700 1 $aGUZMÁN, C.
700 1 $aQUINCKE, M.
700 1 $aSINGH, R. P.
700 1 $aDREISIGACKER, S.
700 1 $aPEÑA, R. J.
700 1 $aFRITZ, AL.
700 1 $aSILVA, P.
700 1 $aPOLAND, J.
700 1 $aGUTIÉRREZ, L.
773 $tThe Plant Genome, 2017$gv.10, Issue 2, 12p. OPEN ACCESS
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
|
|
 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas. |
|
Fecha actual : |
07/11/2018 |
|
Actualizado : |
07/11/2018 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Circulación / Nivel : |
Internacional - -- |
|
Autor : |
CHIAIA, H.L.J.; PERIPOLLI, E.; DE OLIVEIRA SILVA, R.M.; FEITOSA, F.L.B.; DE LEMOS, M.V.A.; BERTON, M.P.; OLIVIERI, B.F.; ESPIGOLAN, R.; TONUSSI, R.L.; GORDO, D.G.M.; DE ALBUQUERQUE, L.G.; DE OLIVEIRA, H.N.; FERRINHO, A.M.; MUELLER, L.F.; KLUSKA, S.; TONHATI, H.; PEREIRA, A.S.C.; AGUILAR, I.; BALDI, F. |
|
Afiliación : |
HERMENEGILDO LUCAS JUSTINO CHIAIA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; ELISA PERIPOLLI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; RAFAEL MEDEIROS DE OLIVEIRA SILVA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; FABIELE LOISE BRAGA FEITOSA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; MARCOS VINÍCIUS ANTUNES DE LEMOS, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; MARIANA PIATTO BERTON, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; BIANCA FERREIRA OLIVIERI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; RAFAEL ESPIGOLAN, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; RAFAEL LARA TONUSSI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; DANIEL GUSTAVO MANSAN GORDO, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; LUCIA GALVÃO DE ALBUQUERQUE, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; HENRIQUE NUNES DE OLIVEIRA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; ADRIELLE MATHIAS FERRINHO, Faculdade de Medicina Veterinária e Zootecnia, USP, Brazil.; LENISE FREITAS MUELLER, Faculdade de Zootecnia e Engenharia de Alimentos, USP, Brazil.; SABRINA KLUSKA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; HUMBERTO TONHATI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; ANGÉLICA SIMONE CRAVO PEREIRA, Faculdade de Medicina Veterinária e Zootecnia, USP, Brazil.; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO BALDI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil. |
|
Título : |
Genomic prediction ability for beef fatty acid profile in Nelore cattle using different pseudo-phenotypes. |
|
Fecha de publicación : |
2018 |
|
Fuente / Imprenta : |
Journal of Applied Genetics, 1 November 2018, volume 59, Issue 4, pages 493-501. |
|
DOI : |
10.1007/s13353-018-0470-5 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received: 15 May 2018 // Revised: 28 August 2018 // Accepted: 17 September 2018. |
|
Contenido : |
ABSTRACT.
The aim of the present study was to compare the predictive ability of SNP-BLUP model using different pseudo-phenotypes such as phenotype adjusted for fixed effects, estimated breeding value, and genomic estimated breeding value, using simulated and real data for beef FA profile of Nelore cattle finished in feedlot. A pedigree with phenotypes and genotypes of 10,000 animals were simulated, considering 50% of multiple sires in the pedigree. Regarding to phenotypes, two traits were simulated, one with high heritability (0.58), another with low heritability (0.13). Ten replicates were performed for each trait and results were averaged among replicates. A historical population was created from generation zero to 2020, with a constant size of 2000 animals (from generation zero to 1000) to produce different levels of linkage disequilibrium (LD). Therefore, there was a gradual reduction in the number of animals (from 2000 to 600), producing a ?bottleneck effect? and consequently, genetic drift and LD starting in the generation 1001 to 2020. A total of 335,000 markers (with MAF greater or equal to 0.02) and 1000 QTL were randomly selected from the last generation of the historical population to generate genotypic data for the test population. The phenotypes were computed as the sum of the QTL effects and an error term sampled from a normal distribution with zero mean and variance equal to 0.88. For simulated data, 4000 animals of the generations 7, 8, and 9 (with genotype and phenotype) were used as training population, and 1000 animals of the last generation (10) were used as validation population. A total of 937 Nelore bulls with phenotype for fatty acid profiles (Sum of saturated, monounsaturated, omega 3, omega 6, ratio of polyunsaturated and saturated and polyunsaturated fatty acid profile) were genotyped using the Illumina BovineHD BeadChip (Illumina, San Diego, CA) with 777,962 SNP. To compare the accuracy and bias of direct genomic value (DGV) for different pseudo-phenotypes, the correlation between true breeding value (TBV) or DGV with pseudo-phenotypes and linear regression coefficient of the pseudo-phenotypes on TBV for simulated data or DGV for real data, respectively. For simulated data, the correlations between DGV and TBV for high heritability traits were higher than obtained with low heritability traits. For simulated and real data, the prediction ability was higher for GEBV than for Yc and EBV. For simulated data, the regression coefficient estimates (b(Yc,DGV)), were on average lower than 1 for high and low heritability traits, being inflated. The results were more biased for Yc and EBV than for GEBV. For real data, the GEBV displayed less biased results compared to Yc and EBV for SFA, MUFA, n-3, n-6, and PUFA/SFA. Despite the less biased results for PUFA using the EBV as pseudo-phenotype, the b(Yi,DGV estimates obtained for the different pseudo-phenotypes (Yc, EBV and GEBV) were very close. Genomic information can assist in improving beef fatty acid profile in Zebu cattle, since the use of genomic information yielded genomic values for fatty acid profile with accuracies ranging from low to moderate. Considering both simulated and real data, the ssGBLUP model is an appropriate alternative to obtain more reliable and less biased GEBVs as pseudo-phenotype in situations of missing pedigree, due to high proportion of multiple sires, being more adequate than EBV and Yc to predict direct genomic value for beef fatty acid profile.
© 2018, Institute of Plant Genetics, Polish Academy of Sciences, Poznan. MenosABSTRACT.
The aim of the present study was to compare the predictive ability of SNP-BLUP model using different pseudo-phenotypes such as phenotype adjusted for fixed effects, estimated breeding value, and genomic estimated breeding value, using simulated and real data for beef FA profile of Nelore cattle finished in feedlot. A pedigree with phenotypes and genotypes of 10,000 animals were simulated, considering 50% of multiple sires in the pedigree. Regarding to phenotypes, two traits were simulated, one with high heritability (0.58), another with low heritability (0.13). Ten replicates were performed for each trait and results were averaged among replicates. A historical population was created from generation zero to 2020, with a constant size of 2000 animals (from generation zero to 1000) to produce different levels of linkage disequilibrium (LD). Therefore, there was a gradual reduction in the number of animals (from 2000 to 600), producing a ?bottleneck effect? and consequently, genetic drift and LD starting in the generation 1001 to 2020. A total of 335,000 markers (with MAF greater or equal to 0.02) and 1000 QTL were randomly selected from the last generation of the historical population to generate genotypic data for the test population. The phenotypes were computed as the sum of the QTL effects and an error term sampled from a normal distribution with zero mean and variance equal to 0.88. For simulated data, 4000 animals of the generations 7, 8, and 9 (with genotype a... Presentar Todo |
|
Palabras claves : |
BOS INDICUS; GENOMIC PREDICTION; LIPID PROFILE; SINGLE-STEP; SNP-BLUP. |
|
Asunto categoría : |
-- |
|
Marc : |
LEADER 04880naa a2200421 a 4500
001 1059280
005 2018-11-07
008 2018 bl uuuu u00u1 u #d
024 7 $a10.1007/s13353-018-0470-5$2DOI
100 1 $aCHIAIA, H.L.J.
245 $aGenomic prediction ability for beef fatty acid profile in Nelore cattle using different pseudo-phenotypes.$h[electronic resource]
260 $c2018
500 $aArticle history: Received: 15 May 2018 // Revised: 28 August 2018 // Accepted: 17 September 2018.
520 $aABSTRACT. The aim of the present study was to compare the predictive ability of SNP-BLUP model using different pseudo-phenotypes such as phenotype adjusted for fixed effects, estimated breeding value, and genomic estimated breeding value, using simulated and real data for beef FA profile of Nelore cattle finished in feedlot. A pedigree with phenotypes and genotypes of 10,000 animals were simulated, considering 50% of multiple sires in the pedigree. Regarding to phenotypes, two traits were simulated, one with high heritability (0.58), another with low heritability (0.13). Ten replicates were performed for each trait and results were averaged among replicates. A historical population was created from generation zero to 2020, with a constant size of 2000 animals (from generation zero to 1000) to produce different levels of linkage disequilibrium (LD). Therefore, there was a gradual reduction in the number of animals (from 2000 to 600), producing a ?bottleneck effect? and consequently, genetic drift and LD starting in the generation 1001 to 2020. A total of 335,000 markers (with MAF greater or equal to 0.02) and 1000 QTL were randomly selected from the last generation of the historical population to generate genotypic data for the test population. The phenotypes were computed as the sum of the QTL effects and an error term sampled from a normal distribution with zero mean and variance equal to 0.88. For simulated data, 4000 animals of the generations 7, 8, and 9 (with genotype and phenotype) were used as training population, and 1000 animals of the last generation (10) were used as validation population. A total of 937 Nelore bulls with phenotype for fatty acid profiles (Sum of saturated, monounsaturated, omega 3, omega 6, ratio of polyunsaturated and saturated and polyunsaturated fatty acid profile) were genotyped using the Illumina BovineHD BeadChip (Illumina, San Diego, CA) with 777,962 SNP. To compare the accuracy and bias of direct genomic value (DGV) for different pseudo-phenotypes, the correlation between true breeding value (TBV) or DGV with pseudo-phenotypes and linear regression coefficient of the pseudo-phenotypes on TBV for simulated data or DGV for real data, respectively. For simulated data, the correlations between DGV and TBV for high heritability traits were higher than obtained with low heritability traits. For simulated and real data, the prediction ability was higher for GEBV than for Yc and EBV. For simulated data, the regression coefficient estimates (b(Yc,DGV)), were on average lower than 1 for high and low heritability traits, being inflated. The results were more biased for Yc and EBV than for GEBV. For real data, the GEBV displayed less biased results compared to Yc and EBV for SFA, MUFA, n-3, n-6, and PUFA/SFA. Despite the less biased results for PUFA using the EBV as pseudo-phenotype, the b(Yi,DGV estimates obtained for the different pseudo-phenotypes (Yc, EBV and GEBV) were very close. Genomic information can assist in improving beef fatty acid profile in Zebu cattle, since the use of genomic information yielded genomic values for fatty acid profile with accuracies ranging from low to moderate. Considering both simulated and real data, the ssGBLUP model is an appropriate alternative to obtain more reliable and less biased GEBVs as pseudo-phenotype in situations of missing pedigree, due to high proportion of multiple sires, being more adequate than EBV and Yc to predict direct genomic value for beef fatty acid profile. © 2018, Institute of Plant Genetics, Polish Academy of Sciences, Poznan.
653 $aBOS INDICUS
653 $aGENOMIC PREDICTION
653 $aLIPID PROFILE
653 $aSINGLE-STEP
653 $aSNP-BLUP
700 1 $aPERIPOLLI, E.
700 1 $aDE OLIVEIRA SILVA, R.M.
700 1 $aFEITOSA, F.L.B.
700 1 $aDE LEMOS, M.V.A.
700 1 $aBERTON, M.P.
700 1 $aOLIVIERI, B.F.
700 1 $aESPIGOLAN, R.
700 1 $aTONUSSI, R.L.
700 1 $aGORDO, D.G.M.
700 1 $aDE ALBUQUERQUE, L.G.
700 1 $aDE OLIVEIRA, H.N.
700 1 $aFERRINHO, A.M.
700 1 $aMUELLER, L.F.
700 1 $aKLUSKA, S.
700 1 $aTONHATI, H.
700 1 $aPEREIRA, A.S.C.
700 1 $aAGUILAR, I.
700 1 $aBALDI, F.
773 $tJournal of Applied Genetics, 1 November 2018, volume 59, Issue 4, pages 493-501.
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
| Expresión de búsqueda válido. Check! |
|
|
