02631naa a2200325 a 450000100080000000500110000800800410001902200140006002400410007410000130011524501170012826000090024550002650025452014830051965000100200265300220201265300100203465300280204470000230207270000160209570000160211170000170212770000210214470000170216570000150218270000140219770000150221170000190222677300600224510574232019-02-20       2017    bl uuuu     u00u1 u    #d  a1940-33727 a10.3835/plantgenome2016.12.01282DOI1 aLADO, B.  aStrategies for selecting crosses using genomic prediction in two wheat breeding programs.h[electronic resource]  c2017  aArticle history: Received: Dec 14, 2016 // Accepted: Mar 18, 2017 // Published: July 6, 2017. B. Lado and S. Battenfield contributed equally.Assigned to Associate Editor Nicholas Tinker. This is an open access article distributed under the CC BY-NC-ND license.  aABSTRACT.  The single most important decision in plant breeding programs is the selection of appropriate crosses. The ideal cross would provide superior predicted progeny performance and enough diversity to maintain genetic gain. The aim of this study was to compare the best crosses predicted using combinations of mid-parent value and variance prediction accounting for linkage disequilibrium (VLD) or assuming linkage equilibrium (VLE). After predicting the mean and the variance of each cross, we selected crosses based on mid-parent value, the top 10% of the progeny, and weighted mean and variance within progenies for grain yield, grain protein content, mixing time, and loaf volume in two applied wheat (Triticum aestivum L.) breeding programs: Instituto Nacional de Investigación Agropecuaria (INIA) Uruguay and CIMMYT Mexico. Although the variance of the progeny is important to increase the chances of finding superior individuals from transgressive segregation, we observed that the mid-parent values of the crosses drove the genetic gain but the variance of the progeny had a small impact on genetic gain for grain yield. However, the relative importance of the variance of the progeny was larger for quality traits. Overall, the genomic resources and the statistical models are now available to plant breeders to predict both the performance of breeding lines per se as well as the value of progeny from any potential crosses.   © Crop Science Society of America  aTRIGO  aGENOMIC SELECTION  aWHEAT  aWHEAT BREEDING PROGRAMS1 aBATTENFIELD, S. D.1 aGUZMÁN, C.1 aQUINCKE, M.1 aSINGH, R. P.1 aDREISIGACKER, S.1 aPEÑA, R. J.1 aFRITZ, AL.1 aSILVA, P.1 aPOLAND, J.1 aGUTIÉRREZ, L.  tThe Plant Genome, 2017gv.10, Issue 2, 12p. OPEN ACCESS