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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
Fecha : |
06/12/2019 |
Actualizado : |
20/04/2020 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
MAYA, L.; MACÍAS-RIOSECO, M.; SILVEIRA, C.S.; GIANNITTI, F.; CASTELLS, M.; RIVERO, R.; CRISTINA, J.; GIANNEECHINI, E.; PUENTES, R.; FLORES, E.F.; RIET-CORREA, F.; COLINA, R. |
Afiliación : |
Laboratorio de Virología Molecular, CENUR Litoral Norte Sede Salto, Universidad de la República, Gral. Rivera 1350, 50000 Salto, Uruguay; MELISSA MACÍAS RIOSECO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CAROLINE DA SILVA SILVEIRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Laboratorio de Virología Molecular, CENUR Litoral Norte Sede Salto, Universidad de la República, Gral. Rivera 1350, 50000 Salto, Uruguay.; DILAVE Miguel C. Rubino, Laboratorio Regional Noroeste, Casilla De Correo, 57037, CP 60000 Paysandú, Uruguay.; Laboratorio de Virología Molecular, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la República, Igua 4225, 11400 Montevideo, Uruguay; DILAVE Miguel C. Rubino, Laboratorio Regional Noroeste, Casilla De Correo, 57037, CP 60000 Paysandú, Uruguay.; Departamento de Ciencias Microbiológicas, Facultad de Veterinaria, Universidad de la República, Lasplaces 1550, 11500 Montevideo, Uruguay.; Sector de Virología, Universidad Federal de Santa María, Santa Maria, Rio Grande do Sul, Brazil.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RODNEY COLINA, Laboratorio de Virología Molecular, CENUR Litoral Norte Sede Salto, Universidad de la República, Gral. Rivera 1350, 50000 Salto, Uruguay. |
Título : |
An extensive field study reveals the circulation of new genetic variants of subtype 1a of bovine viral diarrhea virus in Uruguay. |
Fecha de publicación : |
2020 |
Fuente / Imprenta : |
Archives of Virology, 1 January 2020, Volume 165, Issue 1, Pages 145-156. Doi: https://doi.org/10.1007/s00705-019-04446-z |
DOI : |
10.1007/s00705-019-04446-z |
Idioma : |
Inglés |
Notas : |
Article history:Received: 22 April 2019 / Accepted: 21 September 2019. |
Contenido : |
Abstract:
Bovine viral diarrhea virus (BVDV) is a major pathogen worldwide, causing signifcant economic losses to the livestock sector. In Uruguay, BVDV seroprevalence at the farm level is >80%. In this work, 2546 serum, blood or tissue samples collected from animals suspected of being afected by BVD between 2015 and 2017 were analyzed by reverse transcription PCR and sequencing. Analysis of the BVDV genomic regions 5?UTR/Npro, Npro and E2 revealed that BVDV-1a, 1i and 2b circulate
in the country, with BVDV-1a being the most prevalent subtype. Population dynamics studies revealed that BVDV-1a has been circulating in our herds since ~1990. This subtype began to spread and evolve, accumulating point mutations at a rate of 3.48 × 10?3 substitutions/site/year, acquiring specifc genetic characteristics that gave rise to two local genetic lineages of BVDV-1a. These lineages are divergent from those circulating worldwide, as well as the vaccine strain currently used
in Uruguay. The most notable diferences between feld and vaccine strains were found in the E2 glycoprotein, suggesting that the amino acid substitutions could result in failure of cross-protection/neutralization after vaccination. This is the frst study that compares Uruguayan BVDV feld and vaccine strains with other BVDV strains from throughout the world. The results obtained in this study will be very useful for developing a suitable immunization program for BVDV in Uruguay by
identifying local feld strains as candidates for vaccine development. MenosAbstract:
Bovine viral diarrhea virus (BVDV) is a major pathogen worldwide, causing signifcant economic losses to the livestock sector. In Uruguay, BVDV seroprevalence at the farm level is >80%. In this work, 2546 serum, blood or tissue samples collected from animals suspected of being afected by BVD between 2015 and 2017 were analyzed by reverse transcription PCR and sequencing. Analysis of the BVDV genomic regions 5?UTR/Npro, Npro and E2 revealed that BVDV-1a, 1i and 2b circulate
in the country, with BVDV-1a being the most prevalent subtype. Population dynamics studies revealed that BVDV-1a has been circulating in our herds since ~1990. This subtype began to spread and evolve, accumulating point mutations at a rate of 3.48 × 10?3 substitutions/site/year, acquiring specifc genetic characteristics that gave rise to two local genetic lineages of BVDV-1a. These lineages are divergent from those circulating worldwide, as well as the vaccine strain currently used
in Uruguay. The most notable diferences between feld and vaccine strains were found in the E2 glycoprotein, suggesting that the amino acid substitutions could result in failure of cross-protection/neutralization after vaccination. This is the frst study that compares Uruguayan BVDV feld and vaccine strains with other BVDV strains from throughout the world. The results obtained in this study will be very useful for developing a suitable immunization program for BVDV in Uruguay by
identifying local feld strains as candida... Presentar Todo |
Palabras claves : |
BOVINE VIRAL DIARRHEA (BVD); PLATAFORMA SALUD ANINMAL. |
Thesagro : |
DIARREA. |
Asunto categoría : |
L73 Enfermedades de los animales |
Marc : |
LEADER 02595naa a2200313 a 4500 001 1060513 005 2020-04-20 008 2020 bl uuuu u00u1 u #d 024 7 $a10.1007/s00705-019-04446-z$2DOI 100 1 $aMAYA, L. 245 $aAn extensive field study reveals the circulation of new genetic variants of subtype 1a of bovine viral diarrhea virus in Uruguay.$h[electronic resource] 260 $c2020 500 $aArticle history:Received: 22 April 2019 / Accepted: 21 September 2019. 520 $aAbstract: Bovine viral diarrhea virus (BVDV) is a major pathogen worldwide, causing signifcant economic losses to the livestock sector. In Uruguay, BVDV seroprevalence at the farm level is >80%. In this work, 2546 serum, blood or tissue samples collected from animals suspected of being afected by BVD between 2015 and 2017 were analyzed by reverse transcription PCR and sequencing. Analysis of the BVDV genomic regions 5?UTR/Npro, Npro and E2 revealed that BVDV-1a, 1i and 2b circulate in the country, with BVDV-1a being the most prevalent subtype. Population dynamics studies revealed that BVDV-1a has been circulating in our herds since ~1990. This subtype began to spread and evolve, accumulating point mutations at a rate of 3.48 × 10?3 substitutions/site/year, acquiring specifc genetic characteristics that gave rise to two local genetic lineages of BVDV-1a. These lineages are divergent from those circulating worldwide, as well as the vaccine strain currently used in Uruguay. The most notable diferences between feld and vaccine strains were found in the E2 glycoprotein, suggesting that the amino acid substitutions could result in failure of cross-protection/neutralization after vaccination. This is the frst study that compares Uruguayan BVDV feld and vaccine strains with other BVDV strains from throughout the world. The results obtained in this study will be very useful for developing a suitable immunization program for BVDV in Uruguay by identifying local feld strains as candidates for vaccine development. 650 $aDIARREA 653 $aBOVINE VIRAL DIARRHEA (BVD) 653 $aPLATAFORMA SALUD ANINMAL 700 1 $aMACÍAS-RIOSECO, M. 700 1 $aSILVEIRA, C.S. 700 1 $aGIANNITTI, F. 700 1 $aCASTELLS, M. 700 1 $aRIVERO, R. 700 1 $aCRISTINA, J. 700 1 $aGIANNEECHINI, E. 700 1 $aPUENTES, R. 700 1 $aFLORES, E.F. 700 1 $aRIET-CORREA, F. 700 1 $aCOLINA, R. 773 $tArchives of Virology, 1 January 2020, Volume 165, Issue 1, Pages 145-156. Doi: https://doi.org/10.1007/s00705-019-04446-z
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INIA La Estanzuela (LE) |
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
21/02/2014 |
Actualizado : |
22/02/2014 |
Autor : |
Acosta, Y.M.Delucchi, M.I.Olivera, M.Dieste, C. |
Título : |
Urea en leche: factores que la afectan |
Fecha de publicación : |
2006 |
Fuente / Imprenta : |
Montevideo (Uruguay): INIA, 2006. |
Páginas : |
p. 97-106 |
Serie : |
(INIA Serie Actividades de Difusión ; 455) |
Idioma : |
Español |
Thesagro : |
LECHE; PRODUCCION LECHERA; UREA; URUGUAY. |
Asunto categoría : |
-- |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/472/1/111219220807113651.pdf
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Marc : |
LEADER 00500naa a2200181 a 4500 001 1008060 005 2014-02-22 008 2006 bl uuuu u00u1 u #d 100 1 $aACOSTA, Y.M.DELUCCHI, M.I.OLIVERA, M.DIESTE, C. 245 $aUrea en leche$bfactores que la afectan 260 $c2006 300 $ap. 97-106 490 $a(INIA Serie Actividades de Difusión ; 455) 650 $aLECHE 650 $aPRODUCCION LECHERA 650 $aUREA 650 $aURUGUAY 773 $tMontevideo (Uruguay): INIA, 2006.
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