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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
13/11/2015 |
Actualizado : |
08/02/2023 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
LEGARRA, A.; CHRISTENSEN, O.F.; VITEZICA, Z.G.; AGUILAR, I.; MISZTAL, I. |
Afiliación : |
IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Ancestral relationships using metafounders: Finite ancestral populations and across population relationships. |
Fecha de publicación : |
2015 |
Fuente / Imprenta : |
Genetics, 2015, v.200, no.2, p. 455-468. OPEN ACCESS. doi: https://doi.org/10.1534/genetics.115.177014 |
ISSN : |
0016-6731 |
DOI : |
10.1534/genetics.115.177014 |
Idioma : |
Inglés |
Notas : |
Article history: Received 12 February 2015; Accepted 03 April 2015; Published 14 April 2015. -- |
Contenido : |
ABSTRACT.
Recent use of genomic (marker-based) relationships shows that relationships exist within and across base population (breeds or lines). However, current treatment of pedigree relationships is unable to consider relationships within or across base populations, although such relationships must exist due to finite size of the ancestral population and connections between populations. This complicates the conciliation of both approaches and, in particular, combining pedigree with genomic relationships. We present a coherent theoretical framework to consider base population in pedigree relationships. We suggest a conceptual framework that considers each ancestral population as a finite-sized pool of gametes. This generates across-individual relationships and contrasts with the classical view which each population is considered as an infinite, unrelated pool. Several ancestral populations may be connected and therefore related. Each ancestral population can be represented as a ?metafounder,? a pseudo-individual included as founder of the pedigree and similar to an ?unknown parent group.? Metafounders have self- and across relationships according to a set of parameters, which measure ancestral relationships, i.e., homozygozities within populations and relationships across populations. These parameters can be estimated from existing pedigree and marker genotypes using maximum likelihood or a method based on summary statistics, for arbitrarily complex pedigrees. Equivalences of genetic variance and variance components between the classical and this new parameterization are shown. Segregation variance on crosses of populations is modeled. Efficient algorithms for computation of relationship matrices, their inverses, and inbreeding coefficients are presented. Use of metafounders leads to compatibility of genomic and pedigree relationship matrices and to simple computing algorithms. Examples and code are given.
© 2015 by the Genetics Society of America. MenosABSTRACT.
Recent use of genomic (marker-based) relationships shows that relationships exist within and across base population (breeds or lines). However, current treatment of pedigree relationships is unable to consider relationships within or across base populations, although such relationships must exist due to finite size of the ancestral population and connections between populations. This complicates the conciliation of both approaches and, in particular, combining pedigree with genomic relationships. We present a coherent theoretical framework to consider base population in pedigree relationships. We suggest a conceptual framework that considers each ancestral population as a finite-sized pool of gametes. This generates across-individual relationships and contrasts with the classical view which each population is considered as an infinite, unrelated pool. Several ancestral populations may be connected and therefore related. Each ancestral population can be represented as a ?metafounder,? a pseudo-individual included as founder of the pedigree and similar to an ?unknown parent group.? Metafounders have self- and across relationships according to a set of parameters, which measure ancestral relationships, i.e., homozygozities within populations and relationships across populations. These parameters can be estimated from existing pedigree and marker genotypes using maximum likelihood or a method based on summary statistics, for arbitrarily complex pedigrees. Equivalences... Presentar Todo |
Palabras claves : |
Base populations; Genetic drift; GenPred; Marker genotypes; Pedigree; Relationships; Shared data resource. |
Thesagro : |
GENOMICA; GENOTIPOS; MARCADORES MOLECULARES. |
Asunto categoría : |
L10 Genética y mejoramiento animal |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/5186/1/Aguilar-I.-2015.-Genetics.pdf
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Marc : |
LEADER 03053naa a2200325 a 4500 001 1053877 005 2023-02-08 008 2015 bl uuuu u00u1 u #d 022 $a0016-6731 024 7 $a10.1534/genetics.115.177014$2DOI 100 1 $aLEGARRA, A. 245 $aAncestral relationships using metafounders$bFinite ancestral populations and across population relationships.$h[electronic resource] 260 $c2015 500 $aArticle history: Received 12 February 2015; Accepted 03 April 2015; Published 14 April 2015. -- 520 $aABSTRACT. Recent use of genomic (marker-based) relationships shows that relationships exist within and across base population (breeds or lines). However, current treatment of pedigree relationships is unable to consider relationships within or across base populations, although such relationships must exist due to finite size of the ancestral population and connections between populations. This complicates the conciliation of both approaches and, in particular, combining pedigree with genomic relationships. We present a coherent theoretical framework to consider base population in pedigree relationships. We suggest a conceptual framework that considers each ancestral population as a finite-sized pool of gametes. This generates across-individual relationships and contrasts with the classical view which each population is considered as an infinite, unrelated pool. Several ancestral populations may be connected and therefore related. Each ancestral population can be represented as a ?metafounder,? a pseudo-individual included as founder of the pedigree and similar to an ?unknown parent group.? Metafounders have self- and across relationships according to a set of parameters, which measure ancestral relationships, i.e., homozygozities within populations and relationships across populations. These parameters can be estimated from existing pedigree and marker genotypes using maximum likelihood or a method based on summary statistics, for arbitrarily complex pedigrees. Equivalences of genetic variance and variance components between the classical and this new parameterization are shown. Segregation variance on crosses of populations is modeled. Efficient algorithms for computation of relationship matrices, their inverses, and inbreeding coefficients are presented. Use of metafounders leads to compatibility of genomic and pedigree relationship matrices and to simple computing algorithms. Examples and code are given. © 2015 by the Genetics Society of America. 650 $aGENOMICA 650 $aGENOTIPOS 650 $aMARCADORES MOLECULARES 653 $aBase populations 653 $aGenetic drift 653 $aGenPred 653 $aMarker genotypes 653 $aPedigree 653 $aRelationships 653 $aShared data resource 700 1 $aCHRISTENSEN, O.F. 700 1 $aVITEZICA, Z.G. 700 1 $aAGUILAR, I. 700 1 $aMISZTAL, I. 773 $tGenetics, 2015$gv.200, no.2, p. 455-468. OPEN ACCESS. doi: https://doi.org/10.1534/genetics.115.177014
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INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
06/10/2022 |
Actualizado : |
06/10/2022 |
Tipo de producción científica : |
Informes Agroclimáticos |
Autor : |
INIA (INSTITUTO NACIONAL DE INVESTIGACIÓN AGROPECUARIA); GRAS |
Afiliación : |
UNIDAD DE AGROCLIMA Y SISTEMAS DE INFORMACIÓN, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Informe agroclimático 2022- Situación a Setiembre. |
Fecha de publicación : |
2022 |
Fuente / Imprenta : |
Montevideo (UY): INIA, 2022. |
Páginas : |
6 p. |
Serie : |
(Informe Agroclimático; Año 17, No.9) |
Idioma : |
Español |
Notas : |
Equipo de trabajo INIA-GRAS (Unidad de Agtech y sistemas de Información): Adrián Cal, Guadalupe Tiscornia, Carlos Schiavi, Gabriel García. |
Contenido : |
Contenido. Síntesis de la Situación Agroclimática de Setiembre-- Perspectivas Climáticas Trimestrales elaboradas por el IRI de la Universidad de Columbia (Más información puede encontrarse en el sitio del IRI: http://www.iri.columbia.edu) -- Índice de Vegetación (NDVI) -- Precipitaciones -- Porcentaje de Agua Disponible (PAD) -- Agua No Retenida (ANR) -- Índice de Bienestar Hídrico (IBH) -- Perspectivas Climáticas Oct-Nov-Dic elaboradas por el IRI de la Universidad de Columbia. Destacamos para este mes: Pronóstico de DON en trigo. Mapas nacionales mostrando la estimación de cantidad de DON en trigo a cosecha. Link directo:
http://www.inia.uy/gras/Alertas-y-herramientas/Pron%C3%B3stico-DON-para-trigo- |
Palabras claves : |
AGTECH; BOLETIN AGROCLIMÁTICO; CARACTERIZACIÓN AGROCLIMÁTICA; DIRECCION VIENTO; ESTACIONES AGROMETEOROLOGICAS; ESTACIONES AUTOMATICAS; ESTACIONES INIA; ESTADO DEL TIEMPO; GRAFICAS AGROCLIMATICAS; GRAS; INFORMACION SATELITAL; INFORME AGROCLIMÁTICO 2022; INUNDACIONES; LLUVIAS DIARIAS; MAXIMA; MEDIA; MINIMA; PANEL SOLAR; PERSPECTIVAS CLIMATICAS; PLUVIOMETRO; PRECIPITACION NACIONAL; PREVENCION HELADAS; PRONOSTICO; SENSOR; TANQUE A; TERMOCUPLAS; TERMOHIDROGRAFO; VARIABLES AGROCLIMATICAS; VELETA. |
Thesagro : |
AGROCLIMATOLOGIA; CAMBIO CLIMATICO; CLIMA; CLIMATOLOGIA; ESTACIONES METEOROLOGICAS; ESTRES HIDRICO; EVAPOTRANSPIRACION; HUMEDAD; HUMEDAD RELATIVA; LLUVIA; METEOROLOGIA; PERSPECTIVAS; PLUVIOMETROS; PRONOSTICO DEL TIEMPO; SENSORES; SISTEMAS; SISTEMAS DE INFORMACION; SISTEMAS DE INFORMACION GEOGRAFICOS; TEMPERATURA; TERMOMETROS. |
Asunto categoría : |
P40 Meteorología y climatología |
URL : |
http://www.inia.uy/Publicaciones/Documentos%20compartidos/Informe%20agroclimatico%20INIA-GRAS%20Setiembre%20de%202022.pdf
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Marc : |
LEADER 02890nam a2200745 a 4500 001 1063640 005 2022-10-06 008 2022 bl uuuu u0uu1 u #d 100 1 $aINIA (INSTITUTO NACIONAL DE INVESTIGACIÓN AGROPECUARIA) 245 $aInforme agroclimático 2022- Situación a Setiembre.$h[electronic resource] 260 $aMontevideo (UY): INIA$c2022 300 $a6 p. 490 $a(Informe Agroclimático; Año 17, No.9) 500 $aEquipo de trabajo INIA-GRAS (Unidad de Agtech y sistemas de Información): Adrián Cal, Guadalupe Tiscornia, Carlos Schiavi, Gabriel García. 520 $aContenido. Síntesis de la Situación Agroclimática de Setiembre-- Perspectivas Climáticas Trimestrales elaboradas por el IRI de la Universidad de Columbia (Más información puede encontrarse en el sitio del IRI: http://www.iri.columbia.edu) -- Índice de Vegetación (NDVI) -- Precipitaciones -- Porcentaje de Agua Disponible (PAD) -- Agua No Retenida (ANR) -- Índice de Bienestar Hídrico (IBH) -- Perspectivas Climáticas Oct-Nov-Dic elaboradas por el IRI de la Universidad de Columbia. Destacamos para este mes: Pronóstico de DON en trigo. Mapas nacionales mostrando la estimación de cantidad de DON en trigo a cosecha. Link directo: http://www.inia.uy/gras/Alertas-y-herramientas/Pron%C3%B3stico-DON-para-trigo- 650 $aAGROCLIMATOLOGIA 650 $aCAMBIO CLIMATICO 650 $aCLIMA 650 $aCLIMATOLOGIA 650 $aESTACIONES METEOROLOGICAS 650 $aESTRES HIDRICO 650 $aEVAPOTRANSPIRACION 650 $aHUMEDAD 650 $aHUMEDAD RELATIVA 650 $aLLUVIA 650 $aMETEOROLOGIA 650 $aPERSPECTIVAS 650 $aPLUVIOMETROS 650 $aPRONOSTICO DEL TIEMPO 650 $aSENSORES 650 $aSISTEMAS 650 $aSISTEMAS DE INFORMACION 650 $aSISTEMAS DE INFORMACION GEOGRAFICOS 650 $aTEMPERATURA 650 $aTERMOMETROS 653 $aAGTECH 653 $aBOLETIN AGROCLIMÁTICO 653 $aCARACTERIZACIÓN AGROCLIMÁTICA 653 $aDIRECCION VIENTO 653 $aESTACIONES AGROMETEOROLOGICAS 653 $aESTACIONES AUTOMATICAS 653 $aESTACIONES INIA 653 $aESTADO DEL TIEMPO 653 $aGRAFICAS AGROCLIMATICAS 653 $aGRAS 653 $aINFORMACION SATELITAL 653 $aINFORME AGROCLIMÁTICO 2022 653 $aINUNDACIONES 653 $aLLUVIAS DIARIAS 653 $aMAXIMA 653 $aMEDIA 653 $aMINIMA 653 $aPANEL SOLAR 653 $aPERSPECTIVAS CLIMATICAS 653 $aPLUVIOMETRO 653 $aPRECIPITACION NACIONAL 653 $aPREVENCION HELADAS 653 $aPRONOSTICO 653 $aSENSOR 653 $aTANQUE A 653 $aTERMOCUPLAS 653 $aTERMOHIDROGRAFO 653 $aVARIABLES AGROCLIMATICAS 653 $aVELETA 700 1 $aGRAS
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