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5. | | CASTRO, M.; PEREYRA, S.; VERA, M.; GONZALEZ, N.; CARDOZO, V. Gramíneas: cultivares evaluados en la Estanzuela, Uruguay, durante 2015. 3. Cereales para producción de forraje: culttivares de Avena (Avena byzantina L., Avena sativa L. y Avena Strigosa Schreb.) Cebada forrajera (Hordeum vulgare L.) y Triticale (Triticosecale spp.). In:RESULTADOS EXPERIMENTALES DE LA EVALUACIÓN NACIONAL DE CULTIVARES DE ESPECIES FORRAJERAS: ANUALES, BIANUALES Y PERENNES. Período 2015. La Estanzuela (UY): INASE ; INIA, 2015. p.12-15.Biblioteca(s): INIA La Estanzuela. |
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6. | | PEREYRA, S.; GONZALEZ, N.; STANTON ,J.; CASTRO, M. Integrated management of fusarium head blight in Uruguay. In: International Symposium on Fusarium Head Blight, 5o., International Workshop on Wheat Blast, 2o.,Florianópolis, SC, Brazil,2016. p.96. P49- Session -Epidemiology and Management.Biblioteca(s): INIA La Estanzuela. |
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11. | | AZZIMONTI, G.; GONZALEZ, N.; STANTON, J.; SAINT PIERRE, C.; SINGH, PK.; GERMAN, S.; PEREYRA, S. Precision field-based phenotyping for fusarium head blight, within a new multiple diseases platform in uruguay: 2015 results. In: International Symposium on Fusarium Head Blight, 5o., International Workshop on Wheat Blast, 2o.,Florianópolis, SC, Brazil,2016. p.41. P18: Session 1-Germplasm Development and Breeding for Scab Resistance.Biblioteca(s): INIA La Estanzuela. |
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12. | | ERNST, O.; ESCUDERO, J.; VÁZQUEZ, D.; CADENAZZI, M.; CASTRO, M.; GONZÁLEZ, N.; LARRAMENDI, S.; BENTANCUR, O.; SUBURU, G.; GODIÑO, M. Caracterización de la calidad industrial de variedades de trigo en Uruguay Montevideo (UY): INIA, 2012. 40 p. (Serie FPTA-INIA; 37) Proyecto FPTA 231: Caracterización de la calidad industrial de variedades de trigo sembradas para fabricación de harinas en Uruguay. Período de Ejecución: Nov. 2006-Abr. 2009Biblioteca(s): INIA La Estanzuela; INIA Las Brujas; INIA Tacuarembó. |
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13. | | FARIÑA, L.; BOIDO, E.; ARES, G.; GONZALEZ, N.; LADO, J.; CURBELO, R.; ALMEIDA, L.; MEDINA, K.; CARRAU, F.; DELLACASSA, E, Solid phase microextraction for the characterization of food aroma and particular sensory defects. (Chap.6) In: ACS Symposium Series, 2023, Volume 1433, Pages 299 - 325. Flavors and Fragrances in Food Processing: Preparation and Characterization Methods. Balakrishnan P., Gopi S. (editors). doi: https://doi.org/10.1021/bk-2022-1433.ch006 (ACS Symposium Series; Volume 1433). Chapter book history: Publication Date (Web):December 28, 2022 -- Corresponding author: Dellacassa, E.; Laboratorio de Biotecnología de Aromas, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, Av....Biblioteca(s): INIA Las Brujas. |
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14. | | AZZIMONTI, G.; DOMENIGUINI, V.; GONZALEZ, N.; GARCIA, R.; SAINT-PIERRE, C.; SINGH, P.; QUINCKE, M.; PEREYRA, S.; GERMAN, S. Three years of the Precision Wheat Phenotyping Platform for diseases in Uruguay: current status and future prospects. [Poster]. In: Proceedings of the Borlaug Global Rust Initiative Technical Workshop ,14-18 April, 2018, Marrakesh, Marruecos.Biblioteca(s): INIA La Estanzuela. |
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15. | | AZZIMONTI, G.; GARCIA, R.; GONZALEZ, N.; DOMENIGUINI, V.; CAROLINA SAINT-PIERRE, C.; SINGH, P.K.; QUINCKE, M.; PEREYRA, S.; GERMAN, S. Field-based phenotyping for wheat diseases within a new multiple diseases platform in Uruguay: promoting germplasm sharing to increase resistance diversity. P 309-Topic: Future of Wheat Improvement in Different Parts of the World. In: Buerstmayr, H.; Lang-Mladek, C.; Steiner, B.; Michel, S.; Buerstmayr, M.; Lemmens, M.; Vollmann, J.; Grausgruber, H. (Eds.). Proceedings of the 13th International Wheat Genetics Symposium. Tulln, Austria; April 23-28, 2017. p.485.Biblioteca(s): INIA La Estanzuela. |
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17. | | ARGÜELLES, C.F.; PERCUOCO, C.B.; TALAVERA-STEFANI, L.N.; GONZÁLEZ, N.L.; CARDOZO, A.E.; SOROL, C.B.; CRIVELLO, J.F.; DE BATTISTA, G.A.; RODRIGUEZ, M.E. Calophyllum Brasiliense un recurso nativo de interés en selvas ribereñas. In: INIA TACUAREMBÓ; BENNADJI, Z. (Coord.). Domesticación y diversificación de especies forestales de alto valor: avances y perspectivas. JORNADA TÉCNICA, 27 DE ABRIL, TACUAREMBÓ, URUGUAY, 2017. Tacuarembó (Uruguay): INIA , 2017. p. 8 (INIA Serie Actividades de Difusión ; 774)Biblioteca(s): INIA Tacuarembó. |
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18. | | PEREYRA, S.; CASTRO, M.; VERO, S.; SILVA, P.; CAL, A.; TISCORNIA, G.; GONZALEZ, N.; BENTOS, D.; ALVAREZ, W.; RABAZA, S.; SEVILLANO, L.; BRANCATTI, G.; FRANCIA, C.; RAFFO, M.A.; GERMAN, S.; PÉREZ, C.; GARMENDIA, G.; PAREJA, L.; RODRÍGUEZ, A.; PENDAS, C.; QUINCKE, M.; VÁZQUEZ, D.; RODRIGUEZ, M. Fusariosis de la espiga en trigo y micotoxinas asociadas: contribuyendo a reducir su riesgo. Cultivos. Revista INIA Uruguay, Diciembre 2023, no.75 p.54-58. (Revista INIA; 75).Biblioteca(s): INIA Las Brujas. |
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
21/01/2020 |
Actualizado : |
21/01/2020 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
DE CARVALHO NUNES, L.; STEGELMEIER, B. L.; COOK, D.; PFISTER, J. A.; GARDNER, D. R.; RIET-CORREA, F.; WEICH, K. D. |
Afiliación : |
LOUISIANE DE CARVALHO NUNES, Department of Veterinary Science, Federal University of Espírito Santo, Alegre, Espírito Santo, Brazil; BRYAN L. STEGELMEIER, USDA-ARS Poisonous Plant Research Laboratory, USA; DANIEL COOK, USDA-ARS Poisonous Plant Research Laboratory, USA; JAMES A. PFISTER, USDA-ARS Poisonous Plant Research Laboratory, USA; DALE R. GARDNER, USDA-ARS Poisonous Plant Research Laboratory, USA; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Veterinary Hospital, Center for Health and Rural Technology, Patos Campus, Federal University of Campina Grande, Brazil; KEVIN D. WELCH, USDA-ARS Poisonous Plant Research Laboratory, USA. |
Título : |
Clinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats. |
Fecha de publicación : |
2019 |
Fuente / Imprenta : |
Toxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016 |
ISSN : |
0041-0101 |
DOI : |
10.1016/j.toxicon.2019.09.016 |
Idioma : |
Inglés |
Notas : |
Article history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019. |
Contenido : |
ABSTRACT.
The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic and histochemical studies of the visceral and neurologic lesions observed between goats treated with A. lentiginosus and I. carnea. These findings suggest that I. carnea-induced clinical signs and lesions are due to swainsonine and that calystegines contribute little or nothing to toxicity in goats in the presence of swainsonine.
© 2019 MenosABSTRACT.
The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic a... Presentar Todo |
Palabras claves : |
Astragalus; Calystegines; Ipomoea; Locoweed; PLATAFORMA SALUD ANIMAL; Swainsonine. |
Asunto categoría : |
A50 Investigación agraria |
Marc : |
LEADER 02878naa a2200301 a 4500 001 1060655 005 2020-01-21 008 2019 bl uuuu u00u1 u #d 022 $a0041-0101 024 7 $a10.1016/j.toxicon.2019.09.016$2DOI 100 1 $aDE CARVALHO NUNES, L. 245 $aClinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats.$h[electronic resource] 260 $c2019 500 $aArticle history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019. 520 $aABSTRACT. The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic and histochemical studies of the visceral and neurologic lesions observed between goats treated with A. lentiginosus and I. carnea. These findings suggest that I. carnea-induced clinical signs and lesions are due to swainsonine and that calystegines contribute little or nothing to toxicity in goats in the presence of swainsonine. © 2019 653 $aAstragalus 653 $aCalystegines 653 $aIpomoea 653 $aLocoweed 653 $aPLATAFORMA SALUD ANIMAL 653 $aSwainsonine 700 1 $aSTEGELMEIER, B. L. 700 1 $aCOOK, D. 700 1 $aPFISTER, J. A. 700 1 $aGARDNER, D. R. 700 1 $aRIET-CORREA, F. 700 1 $aWEICH, K. D. 773 $tToxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016
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