|
|
Registro completo
|
Biblioteca (s) : |
INIA Las Brujas; INIA Salto Grande. |
Fecha : |
21/02/2014 |
Actualizado : |
22/02/2014 |
Autor : |
López Bellido, L. ; Castillo García, J.E. ; Robledo de Pedro, F. ; Incertis Carro, F. ; Montero Camacho, J.I. ; Castilla Prados, N. ; Cadahia Lopez, C. ; Ceulemans, E. ; Espinosa Mulas, J. ; Alique, R. ; Plaza, J.L. de la |
Título : |
Nuevas tecnologías en cultivos de invernadero. |
Fecha de publicación : |
1987 |
Fuente / Imprenta : |
Cordoba (España): Universidad de Córdoba, 1987. |
Páginas : |
260 p. |
ISBN : |
ISBN 84-600-4975-2 |
Idioma : |
Español |
Thesagro : |
ADOPCION DE INNOVACIONES; ALMACENAMIENTO; APLICACIONES DEL ORDENADOR; CUBIERTAS DE PLASTICO; CULTIVO IN VITRO; CULTIVO PROTEGIDO; CULTIVOS DE INVERNADERO; ENERGIA SOLAR; ESPAÑA; FERTIRRIGACION; HORTICULTURA; INVERNADEROS; INVESTIGACION; ORGANIZACION DEL TRABAJO; PRODUCCION POTENCIAL; REGULACION DEL CRECIMIENTO; RIEGO POR GOTEO; SELECCION; TECNOLOGIA. |
Asunto categoría : |
-- |
Marc : |
LEADER 01293nam a2200457 a 4500 001 1000628 005 2014-02-22 008 1987 bl uuuu u00u1 u #d 100 1 $aLÓPEZ BELLIDO, L. 245 $aNuevas tecnologías en cultivos de invernadero. 260 $aCordoba (España): Universidad de Córdoba$c1987 300 $a260 p. 650 $aADOPCION DE INNOVACIONES 650 $aALMACENAMIENTO 650 $aAPLICACIONES DEL ORDENADOR 650 $aCUBIERTAS DE PLASTICO 650 $aCULTIVO IN VITRO 650 $aCULTIVO PROTEGIDO 650 $aCULTIVOS DE INVERNADERO 650 $aENERGIA SOLAR 650 $aESPAÑA 650 $aFERTIRRIGACION 650 $aHORTICULTURA 650 $aINVERNADEROS 650 $aINVESTIGACION 650 $aORGANIZACION DEL TRABAJO 650 $aPRODUCCION POTENCIAL 650 $aREGULACION DEL CRECIMIENTO 650 $aRIEGO POR GOTEO 650 $aSELECCION 650 $aTECNOLOGIA 700 1 $aCASTILLO GARCÍA, J.E. 700 1 $aROBLEDO DE PEDRO, F. 700 1 $aINCERTIS CARRO, F. 700 1 $aMONTERO CAMACHO, J.I. 700 1 $aCASTILLA PRADOS, N. 700 1 $aCADAHIA LOPEZ, C. 700 1 $aCEULEMANS, E. 700 1 $aESPINOSA MULAS, J. 700 1 $aALIQUE, R. 700 1 $aPLAZA, J.L. DE LA
Descargar
Esconder MarcPresentar Marc Completo |
Registro original : |
INIA Las Brujas (LB) |
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
|
| Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
Registro completo
|
Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
05/12/2016 |
Actualizado : |
09/10/2019 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
VERDES, J. M.; MÁRQUEZ, M.; CALLIARI, A.; BATES, D.; MORAÑA, J. A.; GIMENO, E. J.; ODRIOZOLA, E.; GIANNITTI, F.; GUERRERO, F.; FIDALGO, L. E.; PUMAROLA, M. |
Afiliación : |
JOSÉ MANUEL VERDES, Universidad de la República (UdelaR)/ Facultad de Veterinaria; MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"); MERCEDES MÁRQUEZ, Universidad de Santiago de Compostela (USC); ALDO CALLIARI, Universidad de la República (UdelaR)/ Facultad de Veterinaria; MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"); DANIEL BATES, Universidad de la República (UdelaR)/ Facultad de Veterinaria; JOSÉ ANTONIO MORAÑA, Universidad de la República (UdelaR)/ Facultad de Veterinaria; EDUARDO JUAN GIMENO, Universidad Nacional de la Plata (UNLP); ERNESTO ODRIOZOLA, INTA (Instituto Nacional de Tecnología Agropecuaria)- Balcarce; FEDERICO GIANNITTI, University of Minnesota, Saint Paul, MN, USA; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FLORENTINA GUERRERO, Universidad de Santiago de Compostela (USC); LUIS EUSEBIO FIDALGO, Universidad de Santiago de Compostela (USC); MARTÍ PUMAROLA, Universitat Autònoma de Barcelona. |
Título : |
A novel pathogenic mechanism for cerebellar lesions produced by Solanum bonariense in cattle. (Full Scientific Report) |
Fecha de publicación : |
2015 |
Fuente / Imprenta : |
Journal of Veterinary Diagnostic Investigation, 2015, v.27 (3): 278-286. |
DOI : |
10.1177/1040638715582048 |
Idioma : |
Inglés |
Notas : |
Article history: First Published April 21, 2015. |
Contenido : |
ABSTRACT.
Intoxication with Solanum bonariense in cattle causes cerebellar cortical degeneration with perikaryal vacuolation, axonal swelling, and death primarily of Purkinje cells, with accumulation of electron-dense residual storage bodies in membrane-bound vesicles. The pathogenesis of this disease is not fully understood. Previously, we proposed that inhibition of protein synthesis in Purkinje cells among other altered metabolic pathways could lead to cytoskeletal alterations, subsequently altering cell-specific axonal transport. In the present study, immunohistochemical and histochemical methods were used to identify neuronal cytoskeletal alterations and axonal loss, demyelination, and astrogliosis in the cerebellum of intoxicated bovines. Samples of cerebellum from 3 natural and 4 experimental cases and 2 control bovines were studied. Immunoreactivity against neurofilament (NF)-200KDa confirmed marked loss of Purkinje neurons, and phospho-NF protein, ?-tubulin, and affinity reaction against phalloidin revealed an altered perikaryal distribution of neuronal cytoskeletal proteins in the remaining Purkinje cells in intoxicated cattle. Reactive astrogliosis in every layer of the cerebellar cortex was also observed with anti?glial fibrillary acidic protein immunohistochemistry. In affected cattle, demyelination and axonal loss in the cerebellar white matter, as well as basket cell loss were demonstrated with Klüver?Barrera and Bielschowsky stains, respectively. Based on these results, we propose that neuronal cytoskeletal alterations with subsequent interference of the axonal transport in Purkinje cells may play a relevant role in the pathogenesis of this neurodegenerative disorder, and also that demyelination and axonal loss in the cerebellar white matter, as well as astrogliosis in the gray matter, likely occur secondarily to Purkinje cell degeneration and death.
© 2015 The Author(s). MenosABSTRACT.
Intoxication with Solanum bonariense in cattle causes cerebellar cortical degeneration with perikaryal vacuolation, axonal swelling, and death primarily of Purkinje cells, with accumulation of electron-dense residual storage bodies in membrane-bound vesicles. The pathogenesis of this disease is not fully understood. Previously, we proposed that inhibition of protein synthesis in Purkinje cells among other altered metabolic pathways could lead to cytoskeletal alterations, subsequently altering cell-specific axonal transport. In the present study, immunohistochemical and histochemical methods were used to identify neuronal cytoskeletal alterations and axonal loss, demyelination, and astrogliosis in the cerebellum of intoxicated bovines. Samples of cerebellum from 3 natural and 4 experimental cases and 2 control bovines were studied. Immunoreactivity against neurofilament (NF)-200KDa confirmed marked loss of Purkinje neurons, and phospho-NF protein, ?-tubulin, and affinity reaction against phalloidin revealed an altered perikaryal distribution of neuronal cytoskeletal proteins in the remaining Purkinje cells in intoxicated cattle. Reactive astrogliosis in every layer of the cerebellar cortex was also observed with anti?glial fibrillary acidic protein immunohistochemistry. In affected cattle, demyelination and axonal loss in the cerebellar white matter, as well as basket cell loss were demonstrated with Klüver?Barrera and Bielschowsky stains, respectively. Based on th... Presentar Todo |
Palabras claves : |
BOVINE; CEREBELLAR DEGENERATION; CYTOSKELETAL DYSFUNCTION; PURKINJE CELLS; SOLANUM BONARIENSE. |
Thesagro : |
BOVINOS. |
Asunto categoría : |
L01 Ganadería |
Marc : |
LEADER 02961naa a2200337 a 4500 001 1056202 005 2019-10-09 008 2015 bl uuuu u00u1 u #d 024 7 $a10.1177/1040638715582048$2DOI 100 1 $aVERDES, J. M. 245 $aA novel pathogenic mechanism for cerebellar lesions produced by Solanum bonariense in cattle. (Full Scientific Report)$h[electronic resource] 260 $c2015 500 $aArticle history: First Published April 21, 2015. 520 $aABSTRACT. Intoxication with Solanum bonariense in cattle causes cerebellar cortical degeneration with perikaryal vacuolation, axonal swelling, and death primarily of Purkinje cells, with accumulation of electron-dense residual storage bodies in membrane-bound vesicles. The pathogenesis of this disease is not fully understood. Previously, we proposed that inhibition of protein synthesis in Purkinje cells among other altered metabolic pathways could lead to cytoskeletal alterations, subsequently altering cell-specific axonal transport. In the present study, immunohistochemical and histochemical methods were used to identify neuronal cytoskeletal alterations and axonal loss, demyelination, and astrogliosis in the cerebellum of intoxicated bovines. Samples of cerebellum from 3 natural and 4 experimental cases and 2 control bovines were studied. Immunoreactivity against neurofilament (NF)-200KDa confirmed marked loss of Purkinje neurons, and phospho-NF protein, ?-tubulin, and affinity reaction against phalloidin revealed an altered perikaryal distribution of neuronal cytoskeletal proteins in the remaining Purkinje cells in intoxicated cattle. Reactive astrogliosis in every layer of the cerebellar cortex was also observed with anti?glial fibrillary acidic protein immunohistochemistry. In affected cattle, demyelination and axonal loss in the cerebellar white matter, as well as basket cell loss were demonstrated with Klüver?Barrera and Bielschowsky stains, respectively. Based on these results, we propose that neuronal cytoskeletal alterations with subsequent interference of the axonal transport in Purkinje cells may play a relevant role in the pathogenesis of this neurodegenerative disorder, and also that demyelination and axonal loss in the cerebellar white matter, as well as astrogliosis in the gray matter, likely occur secondarily to Purkinje cell degeneration and death. © 2015 The Author(s). 650 $aBOVINOS 653 $aBOVINE 653 $aCEREBELLAR DEGENERATION 653 $aCYTOSKELETAL DYSFUNCTION 653 $aPURKINJE CELLS 653 $aSOLANUM BONARIENSE 700 1 $aMÁRQUEZ, M. 700 1 $aCALLIARI, A. 700 1 $aBATES, D. 700 1 $aMORAÑA, J. A. 700 1 $aGIMENO, E. J. 700 1 $aODRIOZOLA, E. 700 1 $aGIANNITTI, F. 700 1 $aGUERRERO, F. 700 1 $aFIDALGO, L. E. 700 1 $aPUMAROLA, M. 773 $tJournal of Veterinary Diagnostic Investigation, 2015$gv.27 (3): 278-286.
Descargar
Esconder MarcPresentar Marc Completo |
Registro original : |
INIA Las Brujas (LB) |
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
Expresión de búsqueda válido. Check! |
|
|