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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
13/11/2015 |
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Actualizado : |
15/10/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
FRAGOMENI, B.O.; LOURENCO, D.A.L.; TSURUTA, S.; MASUDA, Y.; AGUILAR, I.; LEGARRA, A.; LAWLOR, T.J.; MIZTAL, I. |
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Afiliación : |
IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Hot topic: Use of genomic recursions in single-step genomic best linear unbiased predictor (BLUP) with a large number of genotypes. |
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Fecha de publicación : |
2015 |
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Fuente / Imprenta : |
Journal of Dairy Science, 2015, v.98, no.6, p.4090-4094. OPEN ACCESS. |
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ISSN : |
0022-0302 |
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DOI : |
10.3168/jds.2014-9125 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received November 18, 2014 / Accepted March 13, 2015 / Published online: April 8, 2015. |
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Contenido : |
ABSTRACT.
The purpose of this study was to evaluate the accuracy of genomic selection in single-step genomic BLUP (ssGBLUP) when the inverse of the genomic relationship matrix (G) is derived by the "algorithm for proven and young animals" (APY). This algorithm implements genomic recursions on a subset of "proven" animals. Only a relationship matrix for animals treated as "proven" needs to be inverted, and the extra costs of adding animals treated as "young" are linear. Analyses involved 10,102,702 final scores on 6,930,618 Holstein cows. Final score, which is a composite of type traits, is popular trait in the United States and was easily available for this study. A total of 100,000 animals with genotypes were used in the analyses and included 23,000 sires (16,000 with >5 progeny), 27,000 cows, and 50,000 young animals. Genomic EBV (GEBV) were calculated with a regular inverse of G, and with the G inverse approximated by APY. Animals in the proven subset included only sires (23,000), sires + cows (50,000), only cows (27,000), or sires with >5 progeny (16,000). The correlations of GEBV with APY and regular GEBV for young genotyped animals were 0.994, 0.995, 0.992, and 0.992, respectively Later, animals in the proven subset were randomly sampled from all genotyped animals in sets of 2,000, 5,000, 10,000, 15,000, and 20,000; each sample was replicated 4 times. Respective correlations were 0.97 (5,000 sample), 0.98 (10,000 sample), and 0.99 (20,000 sample), with minimal difference between samples of the same size. Genomic EBV with APY were accurate when the number of animals used in the subset is between 10,000 and 20,000, with little difference between the ways of creating the subset. Due to the approximately linear cost of APY, ssGBLUP with APY could support any number of genotyped animals without affecting accuracy.
© 2015 American Dairy Science Association. MenosABSTRACT.
The purpose of this study was to evaluate the accuracy of genomic selection in single-step genomic BLUP (ssGBLUP) when the inverse of the genomic relationship matrix (G) is derived by the "algorithm for proven and young animals" (APY). This algorithm implements genomic recursions on a subset of "proven" animals. Only a relationship matrix for animals treated as "proven" needs to be inverted, and the extra costs of adding animals treated as "young" are linear. Analyses involved 10,102,702 final scores on 6,930,618 Holstein cows. Final score, which is a composite of type traits, is popular trait in the United States and was easily available for this study. A total of 100,000 animals with genotypes were used in the analyses and included 23,000 sires (16,000 with >5 progeny), 27,000 cows, and 50,000 young animals. Genomic EBV (GEBV) were calculated with a regular inverse of G, and with the G inverse approximated by APY. Animals in the proven subset included only sires (23,000), sires + cows (50,000), only cows (27,000), or sires with >5 progeny (16,000). The correlations of GEBV with APY and regular GEBV for young genotyped animals were 0.994, 0.995, 0.992, and 0.992, respectively Later, animals in the proven subset were randomly sampled from all genotyped animals in sets of 2,000, 5,000, 10,000, 15,000, and 20,000; each sample was replicated 4 times. Respective correlations were 0.97 (5,000 sample), 0.98 (10,000 sample), and 0.99 (20,000 sample), with minimal differe... Presentar Todo |
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Palabras claves : |
ANIMALIA; GENOMIC RECURSION; GENOMIC SELECTION; SINGLE-STEP GENOMIC BLUP. |
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Thesagro : |
BLUP; MEJORAMIENTO GENETICO ANIMAL. |
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Asunto categoría : |
L10 Genética y mejoramiento animal |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/5183/1/Aguilar-I.-2015.-Jr.DairyScience-v.984-p.4090-4094.pdf
https://www.journalofdairyscience.org/article/S0022-0302(15)00238-6/pdf
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Marc : |
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008 2015 bl uuuu u00u1 u #d
022 $a0022-0302
024 7 $a10.3168/jds.2014-9125$2DOI
100 1 $aFRAGOMENI, B.O.
245 $aHot topic$bUse of genomic recursions in single-step genomic best linear unbiased predictor (BLUP) with a large number of genotypes.$h[electronic resource]
260 $c2015
500 $aArticle history: Received November 18, 2014 / Accepted March 13, 2015 / Published online: April 8, 2015.
520 $aABSTRACT. The purpose of this study was to evaluate the accuracy of genomic selection in single-step genomic BLUP (ssGBLUP) when the inverse of the genomic relationship matrix (G) is derived by the "algorithm for proven and young animals" (APY). This algorithm implements genomic recursions on a subset of "proven" animals. Only a relationship matrix for animals treated as "proven" needs to be inverted, and the extra costs of adding animals treated as "young" are linear. Analyses involved 10,102,702 final scores on 6,930,618 Holstein cows. Final score, which is a composite of type traits, is popular trait in the United States and was easily available for this study. A total of 100,000 animals with genotypes were used in the analyses and included 23,000 sires (16,000 with >5 progeny), 27,000 cows, and 50,000 young animals. Genomic EBV (GEBV) were calculated with a regular inverse of G, and with the G inverse approximated by APY. Animals in the proven subset included only sires (23,000), sires + cows (50,000), only cows (27,000), or sires with >5 progeny (16,000). The correlations of GEBV with APY and regular GEBV for young genotyped animals were 0.994, 0.995, 0.992, and 0.992, respectively Later, animals in the proven subset were randomly sampled from all genotyped animals in sets of 2,000, 5,000, 10,000, 15,000, and 20,000; each sample was replicated 4 times. Respective correlations were 0.97 (5,000 sample), 0.98 (10,000 sample), and 0.99 (20,000 sample), with minimal difference between samples of the same size. Genomic EBV with APY were accurate when the number of animals used in the subset is between 10,000 and 20,000, with little difference between the ways of creating the subset. Due to the approximately linear cost of APY, ssGBLUP with APY could support any number of genotyped animals without affecting accuracy. © 2015 American Dairy Science Association.
650 $aBLUP
650 $aMEJORAMIENTO GENETICO ANIMAL
653 $aANIMALIA
653 $aGENOMIC RECURSION
653 $aGENOMIC SELECTION
653 $aSINGLE-STEP GENOMIC BLUP
700 1 $aLOURENCO, D.A.L.
700 1 $aTSURUTA, S.
700 1 $aMASUDA, Y.
700 1 $aAGUILAR, I.
700 1 $aLEGARRA, A.
700 1 $aLAWLOR, T.J.
700 1 $aMIZTAL, I.
773 $tJournal of Dairy Science, 2015$gv.98, no.6, p.4090-4094. OPEN ACCESS.
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Registro original : |
INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
24/09/2018 |
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Actualizado : |
07/11/2018 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
FRAGA, M.; FERNÁNDEZ, S.; PERELMUTER, K.; POMMIÉS, N.; CAJARVILLE, C.; ZUNINO, P. |
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Afiliación : |
MARTIN FRAGA COTELO, MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"); INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SOFÍA FERNÁNDEZ, MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"); KAREN PERELMUTER, MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"); NICOLLE POMMIÉS, MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"); Universidad de Nápoles / Facultad de Veterinaria; CECILIA CAJARVILLE, Universidad de Nápoles / Facultad de Veterinaria; PABLO ZUNINO, MEC/ IIBCE (Instituto de Investigaciones de Ciencias Biológicas "Clemente Estable"). |
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Título : |
The use of Prevotella bryantii 3C5 for modulation of the ruminal environment in an ovine model. |
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Complemento del título : |
Veterinary Microbiology. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
Brazilian Journal of Microbiology, November 2018, volume 49, Supplement 1, Pages 101-106. OPEN ACCESS. |
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DOI : |
10.1016/j.bjm.2018.07.004 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 24 April 2018 // Accepted 17 July 2018 // Available online 25 August 2018.
Open Access funded by Sociedade Brasileira de Microbiologia. Under a Creative Commons license. |
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Contenido : |
ABSTRACT.
In the Southern Hemisphere, ruminants are mostly raised in grazing systems where animals consume forage and are supplemented with low amounts of concentrates. Concentrates are usually given separately and are rapidly ingested. This practice leads to changing rumen environment conditions during the day, may alter the rumen microbial metabolism and could affect host performance. The native ruminal Prevotella bryantii strain 3C5 was administered every 48 h to wethers under experimental conditions simulating Southern-Hemisphere feeding to evaluate its potential as a rumen fermentation modulator. The inoculum potential was assessed on day 17. The ammonia nitrogen (NH3-N), volatile fatty acids and ruminal pH were monitored on a 24-h basis 19 days after the beginning of the experiment, and the microbial community structure was assessed by pyrosequencing. The administration of P. bryantii modified the fermentation products and daily pH values compared to the control. The NH3-N concentration in the rumen of treated animals was significantly higher than that of the untreated animals. Modification of the ruminal environment and fermentation pathways was achieved without altering the general structure of the microbial community or the potential methane production. P. bryantii 3C5 could be considered in potential probiotic formulations for ruminants in semi-intensive systems.
© 2018 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. |
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Palabras claves : |
FERMENTATION; OVINE MODEL; PREVOTELLA BRYANTII; PROBIOTICS. |
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Thesagro : |
RUMEN. |
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Asunto categoría : |
L01 Ganadería |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/11695/1/Fraga-M.-et-al-.-2018.-Brazilian-Jr.-of-Microbiology.pdf
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Marc : |
LEADER 02468naa a2200265 a 4500
001 1059072
005 2018-11-07
008 2018 bl uuuu u00u1 u #d
024 7 $a10.1016/j.bjm.2018.07.004$2DOI
100 1 $aFRAGA, M.
245 $aThe use of Prevotella bryantii 3C5 for modulation of the ruminal environment in an ovine model.$h[electronic resource]
260 $c2018
500 $aArticle history: Received 24 April 2018 // Accepted 17 July 2018 // Available online 25 August 2018. Open Access funded by Sociedade Brasileira de Microbiologia. Under a Creative Commons license.
520 $aABSTRACT. In the Southern Hemisphere, ruminants are mostly raised in grazing systems where animals consume forage and are supplemented with low amounts of concentrates. Concentrates are usually given separately and are rapidly ingested. This practice leads to changing rumen environment conditions during the day, may alter the rumen microbial metabolism and could affect host performance. The native ruminal Prevotella bryantii strain 3C5 was administered every 48 h to wethers under experimental conditions simulating Southern-Hemisphere feeding to evaluate its potential as a rumen fermentation modulator. The inoculum potential was assessed on day 17. The ammonia nitrogen (NH3-N), volatile fatty acids and ruminal pH were monitored on a 24-h basis 19 days after the beginning of the experiment, and the microbial community structure was assessed by pyrosequencing. The administration of P. bryantii modified the fermentation products and daily pH values compared to the control. The NH3-N concentration in the rumen of treated animals was significantly higher than that of the untreated animals. Modification of the ruminal environment and fermentation pathways was achieved without altering the general structure of the microbial community or the potential methane production. P. bryantii 3C5 could be considered in potential probiotic formulations for ruminants in semi-intensive systems. © 2018 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda.
650 $aRUMEN
653 $aFERMENTATION
653 $aOVINE MODEL
653 $aPREVOTELLA BRYANTII
653 $aPROBIOTICS
700 1 $aFERNÁNDEZ, S.
700 1 $aPERELMUTER, K.
700 1 $aPOMMIÉS, N.
700 1 $aCAJARVILLE, C.
700 1 $aZUNINO, P.
773 $tBrazilian Journal of Microbiology, November 2018, volume 49, Supplement 1, Pages 101-106. OPEN ACCESS.
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