| |
|
|
| Registros recuperados : 10 | |
| 3. |  | SIGDEL, A.; AGUILAR, I.; ABDOLLAHI-ARPANAHI, R.; PEÑAGARICANO, F. Genetic analysis of heat tolerance for production and health traits in US Holstein cows. Volume Biology & Species - Bovine (dairy) 1, 916. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018. 6 p.| Biblioteca(s): INIA Las Brujas. |
|    |
| 6. | | SIGDEL, A.; LIU, L.; ABDOLLAHI-ARPANAHI, R.; AGUILAR, I.; PEÑAGARICANO, F. Genetic dissection of reproductive performance of dairy cows under heat stress. Animal Genetics, 1 August 2020, Volume 51, Issue 4, Pages 511-520. OPEN ACCESS. Doi: https://doi.org/10.1111/age.12943 Article history: Accepted for publication 31 March 2020. / First published:03 May 2020.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any...| Biblioteca(s): INIA Las Brujas. |
|  |
| 8. | | JARA, E.; PEÑAGARICANO, F.; ARMSTRONG, E.; CIAPPESONI, G.; IRIARTE, A.; NAVAJAS, E. Revealing the genetic basis of eyelid pigmentation in Hereford cattle. Journal of Animal Science, 2022, Volume 100, Issue 5. doi: https://doi.org/10.1093/jas/skac110 Article history: Received December 14, 2021; Accepted April 4, 2022; Advance access publication 7 April 2022.
Corresponding author: Eugenio Jara, email: eugeniojara19@gmail.com --| Biblioteca(s): INIA Las Brujas. |
|  |
| 9. | | MEIKLE, A.; CAVESTANY, D.; CARRIQUIRY, M.; ADRIEN, M.L.; RUPRECHTER, G.; ROVERE, G.; PEÑAGARICANO, F.; MENDOZA, A.; PEREIRA, I.; MATTIAUDA, D.; CHILIBROSTE, P. Endocrinología metabólica en la vaca lechera durante el período de transición y su relación con el reinicio de la ciclicidad ovárica. Agrociencia (Uruguay), v. 14, n, 3, p. 89-95, 2010. Agrociencia, Nro especial: Congreso Asociación Uruguaya de Producción Animal, 3., 4-5 Noviembre 2010, Montevideo, UY: INIA, Facultad de Agronomía, SMVU.| Biblioteca(s): INIA La Estanzuela. |
| |
| 10. | | DEVINCENZI, T.; MARÍN, M.F.; CUADRO, P.; RUGGIA, A.; DEL PINO, M.L.; FRUGONI, J.C.; LEMA, O.M.; CALISTRO, A.; LUZARDO, S.; BRITO, G.; CARRIQUIRY, M.; ARMSTRONG, E.; PEÑAGARICANO, F.; JARA, E. Núcleo Informativo Hereford de la Unidad Glencoe? INIA Tacuarembó. Anuario Hereford (Montevideo), 2020, p. 214-215.| Biblioteca(s): INIA La Estanzuela; INIA Tacuarembó. |
| |
| Registros recuperados : 10 | |
|
|
|
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas. |
|
Fecha actual : |
29/05/2020 |
|
Actualizado : |
12/02/2021 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Circulación / Nivel : |
Internacional - -- |
|
Autor : |
SIGDEL, A.; LIU, L.; ABDOLLAHI-ARPANAHI, R.; AGUILAR, I.; PEÑAGARICANO, F. |
|
Afiliación : |
ANIL SIGDEL, Department of Animal Sciences, University of Florida, Gainesville, FL,USA.; L. LIU, Department of Animal Sciences, University of Florida, Gainesville, FL,USA.; ROSTAM ABDOLLAHI-ARPANAHI, Department of Animal Sciences, University of Florida, Gainesville, FL,USA.; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FRANCISCO PEÑAGARICANO, University of Florida Genetics Institute, University of Florida, Gainesville, FL, USA. |
|
Título : |
Genetic dissection of reproductive performance of dairy cows under heat stress. |
|
Fecha de publicación : |
2020 |
|
Fuente / Imprenta : |
Animal Genetics, 1 August 2020, Volume 51, Issue 4, Pages 511-520. OPEN ACCESS. Doi: https://doi.org/10.1111/age.12943 |
|
ISSN : |
0268-9146 |
|
DOI : |
10.1111/age.12943 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Accepted for publication 31 March 2020. / First published:03 May 2020.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Corresponding author: Peñagaricano, F.; Department of Animal Sciences, University of Florida, Gainesville, FL, United States; email:fpenagaricano@ufl.edu |
|
Contenido : |
ABSTRACT.
Heat stress negatively impacts the reproductive performance of dairy cows. The main objective of this study was to dissect the genetic basis underlying dairy cow fertility under heat stress conditions. Our first goal was to estimate genetic components of cow conception across lactations considering heat stress. Our second goal was to reveal individual genes and functional gene-sets that explain a cow?s ability to conceive under thermal stress. Data consisted of 74 221 insemination records on 13 704 Holstein cows. Multitrait linear repeatability test-day models with random regressions on a function of temperature?humidity index values were used for the analyses. Heritability estimates for cow conception under heat stress were around 2?3%, whereas genetic correlations between general and thermotolerance additive genetic effects were negative and ranged between ?0.35 and ?0.82, indicating an unfavorable relationship between cows? ability to conceive under thermo-neutral vs. thermo-stress conditions. Whole-genome scans identified at least six genomic regions on BTA1, BTA10, BTA11, BTA17, BTA21 and BTA23 associated with conception under thermal stress. These regions harbor candidate genes such as BRWD1, EXD2, ADAM20, EPAS1, TAOK3, and NOS1, which are directly implicated in reproductive functions and cellular response to heat stress. The gene-set enrichment analysis revealed functional terms related to fertilization, developmental biology, heat shock proteins and oxidative stress, among others. Overall, our findings contribute to a better understanding of the genetics underlying the reproductive performance of dairy cattle under heat stress conditions and point out novel genomic strategies for improving thermotolerance and fertility via marker-assisted breeding.
© 2020 The Authors. Animal Genetics published by John Wiley & Sons Ltd on behalf of Stichting International Foundation for Animal Genetics MenosABSTRACT.
Heat stress negatively impacts the reproductive performance of dairy cows. The main objective of this study was to dissect the genetic basis underlying dairy cow fertility under heat stress conditions. Our first goal was to estimate genetic components of cow conception across lactations considering heat stress. Our second goal was to reveal individual genes and functional gene-sets that explain a cow?s ability to conceive under thermal stress. Data consisted of 74 221 insemination records on 13 704 Holstein cows. Multitrait linear repeatability test-day models with random regressions on a function of temperature?humidity index values were used for the analyses. Heritability estimates for cow conception under heat stress were around 2?3%, whereas genetic correlations between general and thermotolerance additive genetic effects were negative and ranged between ?0.35 and ?0.82, indicating an unfavorable relationship between cows? ability to conceive under thermo-neutral vs. thermo-stress conditions. Whole-genome scans identified at least six genomic regions on BTA1, BTA10, BTA11, BTA17, BTA21 and BTA23 associated with conception under thermal stress. These regions harbor candidate genes such as BRWD1, EXD2, ADAM20, EPAS1, TAOK3, and NOS1, which are directly implicated in reproductive functions and cellular response to heat stress. The gene-set enrichment analysis revealed functional terms related to fertilization, developmental biology, heat shock proteins and oxidati... Presentar Todo |
|
Palabras claves : |
Cow conception rate; Pathway analysis; Thermotolerance; Whole-genome scan. |
|
Asunto categoría : |
-- |
|
URL : |
https://onlinelibrary.wiley.com/doi/epdf/10.1111/age.12943
|
|
Marc : |
LEADER 03198naa a2200253 a 4500
001 1061089
005 2021-02-12
008 2020 bl uuuu u00u1 u #d
022 $a0268-9146
024 7 $a10.1111/age.12943$2DOI
100 1 $aSIGDEL, A.
245 $aGenetic dissection of reproductive performance of dairy cows under heat stress.$h[electronic resource]
260 $c2020
500 $aArticle history: Accepted for publication 31 March 2020. / First published:03 May 2020. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Corresponding author: Peñagaricano, F.; Department of Animal Sciences, University of Florida, Gainesville, FL, United States; email:fpenagaricano@ufl.edu
520 $aABSTRACT. Heat stress negatively impacts the reproductive performance of dairy cows. The main objective of this study was to dissect the genetic basis underlying dairy cow fertility under heat stress conditions. Our first goal was to estimate genetic components of cow conception across lactations considering heat stress. Our second goal was to reveal individual genes and functional gene-sets that explain a cow?s ability to conceive under thermal stress. Data consisted of 74 221 insemination records on 13 704 Holstein cows. Multitrait linear repeatability test-day models with random regressions on a function of temperature?humidity index values were used for the analyses. Heritability estimates for cow conception under heat stress were around 2?3%, whereas genetic correlations between general and thermotolerance additive genetic effects were negative and ranged between ?0.35 and ?0.82, indicating an unfavorable relationship between cows? ability to conceive under thermo-neutral vs. thermo-stress conditions. Whole-genome scans identified at least six genomic regions on BTA1, BTA10, BTA11, BTA17, BTA21 and BTA23 associated with conception under thermal stress. These regions harbor candidate genes such as BRWD1, EXD2, ADAM20, EPAS1, TAOK3, and NOS1, which are directly implicated in reproductive functions and cellular response to heat stress. The gene-set enrichment analysis revealed functional terms related to fertilization, developmental biology, heat shock proteins and oxidative stress, among others. Overall, our findings contribute to a better understanding of the genetics underlying the reproductive performance of dairy cattle under heat stress conditions and point out novel genomic strategies for improving thermotolerance and fertility via marker-assisted breeding. © 2020 The Authors. Animal Genetics published by John Wiley & Sons Ltd on behalf of Stichting International Foundation for Animal Genetics
653 $aCow conception rate
653 $aPathway analysis
653 $aThermotolerance
653 $aWhole-genome scan
700 1 $aLIU, L.
700 1 $aABDOLLAHI-ARPANAHI, R.
700 1 $aAGUILAR, I.
700 1 $aPEÑAGARICANO, F.
773 $tAnimal Genetics, 1 August 2020, Volume 51, Issue 4, Pages 511-520. OPEN ACCESS. Doi: https://doi.org/10.1111/age.12943
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
| Expresión de búsqueda válido. Check! |
|
|
