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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
07/11/2018 |
Actualizado : |
07/11/2018 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
CHIAIA, H.L.J.; PERIPOLLI, E.; DE OLIVEIRA SILVA, R.M.; FEITOSA, F.L.B.; DE LEMOS, M.V.A.; BERTON, M.P.; OLIVIERI, B.F.; ESPIGOLAN, R.; TONUSSI, R.L.; GORDO, D.G.M.; DE ALBUQUERQUE, L.G.; DE OLIVEIRA, H.N.; FERRINHO, A.M.; MUELLER, L.F.; KLUSKA, S.; TONHATI, H.; PEREIRA, A.S.C.; AGUILAR, I.; BALDI, F. |
Afiliación : |
HERMENEGILDO LUCAS JUSTINO CHIAIA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; ELISA PERIPOLLI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; RAFAEL MEDEIROS DE OLIVEIRA SILVA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; FABIELE LOISE BRAGA FEITOSA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; MARCOS VINÍCIUS ANTUNES DE LEMOS, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; MARIANA PIATTO BERTON, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; BIANCA FERREIRA OLIVIERI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; RAFAEL ESPIGOLAN, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; RAFAEL LARA TONUSSI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; DANIEL GUSTAVO MANSAN GORDO, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; LUCIA GALVÃO DE ALBUQUERQUE, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; HENRIQUE NUNES DE OLIVEIRA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; ADRIELLE MATHIAS FERRINHO, Faculdade de Medicina Veterinária e Zootecnia, USP, Brazil.; LENISE FREITAS MUELLER, Faculdade de Zootecnia e Engenharia de Alimentos, USP, Brazil.; SABRINA KLUSKA, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; HUMBERTO TONHATI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.; ANGÉLICA SIMONE CRAVO PEREIRA, Faculdade de Medicina Veterinária e Zootecnia, USP, Brazil.; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO BALDI, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil. |
Título : |
Genomic prediction ability for beef fatty acid profile in Nelore cattle using different pseudo-phenotypes. |
Fecha de publicación : |
2018 |
Fuente / Imprenta : |
Journal of Applied Genetics, 1 November 2018, volume 59, Issue 4, pages 493-501. |
DOI : |
10.1007/s13353-018-0470-5 |
Idioma : |
Inglés |
Notas : |
Article history: Received: 15 May 2018 // Revised: 28 August 2018 // Accepted: 17 September 2018. |
Contenido : |
ABSTRACT.
The aim of the present study was to compare the predictive ability of SNP-BLUP model using different pseudo-phenotypes such as phenotype adjusted for fixed effects, estimated breeding value, and genomic estimated breeding value, using simulated and real data for beef FA profile of Nelore cattle finished in feedlot. A pedigree with phenotypes and genotypes of 10,000 animals were simulated, considering 50% of multiple sires in the pedigree. Regarding to phenotypes, two traits were simulated, one with high heritability (0.58), another with low heritability (0.13). Ten replicates were performed for each trait and results were averaged among replicates. A historical population was created from generation zero to 2020, with a constant size of 2000 animals (from generation zero to 1000) to produce different levels of linkage disequilibrium (LD). Therefore, there was a gradual reduction in the number of animals (from 2000 to 600), producing a ?bottleneck effect? and consequently, genetic drift and LD starting in the generation 1001 to 2020. A total of 335,000 markers (with MAF greater or equal to 0.02) and 1000 QTL were randomly selected from the last generation of the historical population to generate genotypic data for the test population. The phenotypes were computed as the sum of the QTL effects and an error term sampled from a normal distribution with zero mean and variance equal to 0.88. For simulated data, 4000 animals of the generations 7, 8, and 9 (with genotype and phenotype) were used as training population, and 1000 animals of the last generation (10) were used as validation population. A total of 937 Nelore bulls with phenotype for fatty acid profiles (Sum of saturated, monounsaturated, omega 3, omega 6, ratio of polyunsaturated and saturated and polyunsaturated fatty acid profile) were genotyped using the Illumina BovineHD BeadChip (Illumina, San Diego, CA) with 777,962 SNP. To compare the accuracy and bias of direct genomic value (DGV) for different pseudo-phenotypes, the correlation between true breeding value (TBV) or DGV with pseudo-phenotypes and linear regression coefficient of the pseudo-phenotypes on TBV for simulated data or DGV for real data, respectively. For simulated data, the correlations between DGV and TBV for high heritability traits were higher than obtained with low heritability traits. For simulated and real data, the prediction ability was higher for GEBV than for Yc and EBV. For simulated data, the regression coefficient estimates (b(Yc,DGV)), were on average lower than 1 for high and low heritability traits, being inflated. The results were more biased for Yc and EBV than for GEBV. For real data, the GEBV displayed less biased results compared to Yc and EBV for SFA, MUFA, n-3, n-6, and PUFA/SFA. Despite the less biased results for PUFA using the EBV as pseudo-phenotype, the b(Yi,DGV estimates obtained for the different pseudo-phenotypes (Yc, EBV and GEBV) were very close. Genomic information can assist in improving beef fatty acid profile in Zebu cattle, since the use of genomic information yielded genomic values for fatty acid profile with accuracies ranging from low to moderate. Considering both simulated and real data, the ssGBLUP model is an appropriate alternative to obtain more reliable and less biased GEBVs as pseudo-phenotype in situations of missing pedigree, due to high proportion of multiple sires, being more adequate than EBV and Yc to predict direct genomic value for beef fatty acid profile.
© 2018, Institute of Plant Genetics, Polish Academy of Sciences, Poznan. MenosABSTRACT.
The aim of the present study was to compare the predictive ability of SNP-BLUP model using different pseudo-phenotypes such as phenotype adjusted for fixed effects, estimated breeding value, and genomic estimated breeding value, using simulated and real data for beef FA profile of Nelore cattle finished in feedlot. A pedigree with phenotypes and genotypes of 10,000 animals were simulated, considering 50% of multiple sires in the pedigree. Regarding to phenotypes, two traits were simulated, one with high heritability (0.58), another with low heritability (0.13). Ten replicates were performed for each trait and results were averaged among replicates. A historical population was created from generation zero to 2020, with a constant size of 2000 animals (from generation zero to 1000) to produce different levels of linkage disequilibrium (LD). Therefore, there was a gradual reduction in the number of animals (from 2000 to 600), producing a ?bottleneck effect? and consequently, genetic drift and LD starting in the generation 1001 to 2020. A total of 335,000 markers (with MAF greater or equal to 0.02) and 1000 QTL were randomly selected from the last generation of the historical population to generate genotypic data for the test population. The phenotypes were computed as the sum of the QTL effects and an error term sampled from a normal distribution with zero mean and variance equal to 0.88. For simulated data, 4000 animals of the generations 7, 8, and 9 (with genotype a... Presentar Todo |
Palabras claves : |
BOS INDICUS; GENOMIC PREDICTION; LIPID PROFILE; SINGLE-STEP; SNP-BLUP. |
Asunto categoría : |
-- |
Marc : |
LEADER 04880naa a2200421 a 4500 001 1059280 005 2018-11-07 008 2018 bl uuuu u00u1 u #d 024 7 $a10.1007/s13353-018-0470-5$2DOI 100 1 $aCHIAIA, H.L.J. 245 $aGenomic prediction ability for beef fatty acid profile in Nelore cattle using different pseudo-phenotypes.$h[electronic resource] 260 $c2018 500 $aArticle history: Received: 15 May 2018 // Revised: 28 August 2018 // Accepted: 17 September 2018. 520 $aABSTRACT. The aim of the present study was to compare the predictive ability of SNP-BLUP model using different pseudo-phenotypes such as phenotype adjusted for fixed effects, estimated breeding value, and genomic estimated breeding value, using simulated and real data for beef FA profile of Nelore cattle finished in feedlot. A pedigree with phenotypes and genotypes of 10,000 animals were simulated, considering 50% of multiple sires in the pedigree. Regarding to phenotypes, two traits were simulated, one with high heritability (0.58), another with low heritability (0.13). Ten replicates were performed for each trait and results were averaged among replicates. A historical population was created from generation zero to 2020, with a constant size of 2000 animals (from generation zero to 1000) to produce different levels of linkage disequilibrium (LD). Therefore, there was a gradual reduction in the number of animals (from 2000 to 600), producing a ?bottleneck effect? and consequently, genetic drift and LD starting in the generation 1001 to 2020. A total of 335,000 markers (with MAF greater or equal to 0.02) and 1000 QTL were randomly selected from the last generation of the historical population to generate genotypic data for the test population. The phenotypes were computed as the sum of the QTL effects and an error term sampled from a normal distribution with zero mean and variance equal to 0.88. For simulated data, 4000 animals of the generations 7, 8, and 9 (with genotype and phenotype) were used as training population, and 1000 animals of the last generation (10) were used as validation population. A total of 937 Nelore bulls with phenotype for fatty acid profiles (Sum of saturated, monounsaturated, omega 3, omega 6, ratio of polyunsaturated and saturated and polyunsaturated fatty acid profile) were genotyped using the Illumina BovineHD BeadChip (Illumina, San Diego, CA) with 777,962 SNP. To compare the accuracy and bias of direct genomic value (DGV) for different pseudo-phenotypes, the correlation between true breeding value (TBV) or DGV with pseudo-phenotypes and linear regression coefficient of the pseudo-phenotypes on TBV for simulated data or DGV for real data, respectively. For simulated data, the correlations between DGV and TBV for high heritability traits were higher than obtained with low heritability traits. For simulated and real data, the prediction ability was higher for GEBV than for Yc and EBV. For simulated data, the regression coefficient estimates (b(Yc,DGV)), were on average lower than 1 for high and low heritability traits, being inflated. The results were more biased for Yc and EBV than for GEBV. For real data, the GEBV displayed less biased results compared to Yc and EBV for SFA, MUFA, n-3, n-6, and PUFA/SFA. Despite the less biased results for PUFA using the EBV as pseudo-phenotype, the b(Yi,DGV estimates obtained for the different pseudo-phenotypes (Yc, EBV and GEBV) were very close. Genomic information can assist in improving beef fatty acid profile in Zebu cattle, since the use of genomic information yielded genomic values for fatty acid profile with accuracies ranging from low to moderate. Considering both simulated and real data, the ssGBLUP model is an appropriate alternative to obtain more reliable and less biased GEBVs as pseudo-phenotype in situations of missing pedigree, due to high proportion of multiple sires, being more adequate than EBV and Yc to predict direct genomic value for beef fatty acid profile. © 2018, Institute of Plant Genetics, Polish Academy of Sciences, Poznan. 653 $aBOS INDICUS 653 $aGENOMIC PREDICTION 653 $aLIPID PROFILE 653 $aSINGLE-STEP 653 $aSNP-BLUP 700 1 $aPERIPOLLI, E. 700 1 $aDE OLIVEIRA SILVA, R.M. 700 1 $aFEITOSA, F.L.B. 700 1 $aDE LEMOS, M.V.A. 700 1 $aBERTON, M.P. 700 1 $aOLIVIERI, B.F. 700 1 $aESPIGOLAN, R. 700 1 $aTONUSSI, R.L. 700 1 $aGORDO, D.G.M. 700 1 $aDE ALBUQUERQUE, L.G. 700 1 $aDE OLIVEIRA, H.N. 700 1 $aFERRINHO, A.M. 700 1 $aMUELLER, L.F. 700 1 $aKLUSKA, S. 700 1 $aTONHATI, H. 700 1 $aPEREIRA, A.S.C. 700 1 $aAGUILAR, I. 700 1 $aBALDI, F. 773 $tJournal of Applied Genetics, 1 November 2018, volume 59, Issue 4, pages 493-501.
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INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
18/06/2015 |
Actualizado : |
18/06/2015 |
Tipo de producción científica : |
Informes Agroclimáticos |
Autor : |
CASTAÑO, J.; GIMENEZ, A.; FUREST, J.; OLIVERA, L. |
Afiliación : |
JOSE PEDRO CASTAÑO SANCHEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; AGUSTIN EDUARDO GIMENEZ FUREST, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JOSE MARIA FUREST CROCCO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; LAURA OLIVERA MC ALISTER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Informe Agroclimático 2007 - Situación a Marzo. |
Fecha de publicación : |
2007 |
Fuente / Imprenta : |
Montevideo (Uruguay): INIA, 2007 |
Páginas : |
8 p. |
Idioma : |
Español |
Palabras claves : |
AGROCLIMA; AGROCLIMATOLOGÍA; BOLETIN AGROCLIMÁTICO; CARACTERIZACIÓN AGROCLIMÁTICA; DIRECCION VIENTO; ESTACIONES AGROMETEOROLOGICAS; ESTACIONES AUTOMATICAS; ESTACIONES INIA; ESTADO DEL TIEMPO; ESTRÉS HÍDRICO; GRAFICAS AGROCLIMATICOS; GRAS; HELIOFANOGRAFO; INFORMACION SATELITAL; INUNDACIONES; LLUVIAS DIARIAS; MAXIMA; MEDIA; MINIMA; PANEL SOLAR; PERSPECTIVAS CLIMATICAS; PLUVIOMETRO; PRECIPITACION NACIONAL; PREVENCION HELADAS; PRONOSTICO; SENSOR; SIMETRICO; TANQUE A; TERMOCUPLAS; TERMOHIDROGRAFO; VARIABLES AGROCLIMATICAS; VELETA. |
Thesagro : |
AGROCLIMATOLOGIA; CAMBIO CLIMATICO; CLIMA; CLIMATOLOGIA; ESTACIONES METEOROLOGICAS; ESTRES HIDRICO; EVAPORACION; EVAPOTRANSPIRACION; HUMEDAD; HUMEDAD RELATIVA; LLUVIA; METEOROLOGIA; PERSPECTIVAS; PLUVIOMETROS; PRONOSTICO DEL TIEMPO; SENSORES; SISTEMAS; SISTEMAS DE INFORMACION; SUELO; TEMPERATURA; TERMOMETROS. |
Asunto categoría : |
P40 Meteorología y climatología |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/4632/1/Inf.Agr.-marzo-2007.pdf
http://www.inia.uy/Publicaciones/Paginas/publicacion-1440.aspx
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Marc : |
LEADER 02037nam a2200781 a 4500 001 1052787 005 2015-06-18 008 2007 bl uuuu u0uu1 u #d 100 1 $aCASTAÑO, J. 245 $aInforme Agroclimático 2007 - Situación a Marzo.$h[electronic resource] 260 $aMontevideo (Uruguay): INIA$c2007 300 $a8 p. 650 $aAGROCLIMATOLOGIA 650 $aCAMBIO CLIMATICO 650 $aCLIMA 650 $aCLIMATOLOGIA 650 $aESTACIONES METEOROLOGICAS 650 $aESTRES HIDRICO 650 $aEVAPORACION 650 $aEVAPOTRANSPIRACION 650 $aHUMEDAD 650 $aHUMEDAD RELATIVA 650 $aLLUVIA 650 $aMETEOROLOGIA 650 $aPERSPECTIVAS 650 $aPLUVIOMETROS 650 $aPRONOSTICO DEL TIEMPO 650 $aSENSORES 650 $aSISTEMAS 650 $aSISTEMAS DE INFORMACION 650 $aSUELO 650 $aTEMPERATURA 650 $aTERMOMETROS 653 $aAGROCLIMA 653 $aAGROCLIMATOLOGÍA 653 $aBOLETIN AGROCLIMÁTICO 653 $aCARACTERIZACIÓN AGROCLIMÁTICA 653 $aDIRECCION VIENTO 653 $aESTACIONES AGROMETEOROLOGICAS 653 $aESTACIONES AUTOMATICAS 653 $aESTACIONES INIA 653 $aESTADO DEL TIEMPO 653 $aESTRÉS HÍDRICO 653 $aGRAFICAS AGROCLIMATICOS 653 $aGRAS 653 $aHELIOFANOGRAFO 653 $aINFORMACION SATELITAL 653 $aINUNDACIONES 653 $aLLUVIAS DIARIAS 653 $aMAXIMA 653 $aMEDIA 653 $aMINIMA 653 $aPANEL SOLAR 653 $aPERSPECTIVAS CLIMATICAS 653 $aPLUVIOMETRO 653 $aPRECIPITACION NACIONAL 653 $aPREVENCION HELADAS 653 $aPRONOSTICO 653 $aSENSOR 653 $aSIMETRICO 653 $aTANQUE A 653 $aTERMOCUPLAS 653 $aTERMOHIDROGRAFO 653 $aVARIABLES AGROCLIMATICAS 653 $aVELETA 700 1 $aGIMENEZ, A. 700 1 $aFUREST, J. 700 1 $aOLIVERA, L.
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