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| Registros recuperados : 183 | |
| 3. |  | DORSCH, M.; GIANNITTI, F. Bovine listeric encephalitis (encephalic listeriosis). Diagnostic Exercise From The Davis-Thompson Foundation*, Answer Sheet, Case # 170, August 2021. *The Diagnostic Exercises are an initiative of the Latin Comparative Pathology Group (LCPG), the Latin American subdivision of The Davis-Thompson Foundation. These exercises are contributed by members and non-members from any country of...| Biblioteca(s): INIA Las Brujas. |
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| 9. | | CAFFARENA, D.; RIET-CORREA, F.; GIANNITTI, F. Uso de protocolos de manejo del dolor durante el desbotonamiento y descorne de las terneras de tambo: ¿Qué tan común es en Uruguay y Argentina?. In: Jornadas Uruguayas de Buiatría, 45., 2017, Paysandú, Uy., Matto, C.; Delpiazzo, R.(Ed.). Trabajos presentados. Paysandú: Centro Médico Veterinario de Paysandú/Sociedad Uruguaya de Buiatría, 2017. p.212-214.| Biblioteca(s): INIA La Estanzuela. |
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| 11. | | GIANNITTI, F.; SADEGHI, M.; DELWART, E.; SCHWABENLANDER, M.; FOYLEY, J. Aleutian disease virus-like virus (Amdoparvovirus sp.) infecting free-ranging striped skunks (Mephitis mephitis) in the Midwestern USA. (Letter) Journal of Wildlife Diseases, 1 January 2018, Volume 54, Issue 1, Pages 186-188. Article history: Received: April 9, 2017 // Accepted: May 26, 2017.| Biblioteca(s): INIA La Estanzuela. |
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| 12. | | MAURENTE BERÓN, M.; FERNÁNDEZ-CIGANDA, S.; GIANNITTI, F.; FRAGA, M. Comparison of PCR and qPCR for the detection of Mycobacterium avium subsp. paratuberculosis in feces and milk of dairy cows in Uruguay: a longitudinal study. (ID-P47). [poster-Infectious Diseases] Session: Posters. In: World Buiatrics Congress (WBC), 31 st., Abstract Book, Madrid, Spain, September 4-8, 2022.| Biblioteca(s): INIA Las Brujas. |
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| 13. | | SCHILD, C.; CAFFARENA, D.; RIET-CORREA, F.; GIANNITTI, F. Enfermedad articular degenerativa de las rodillas en una vaca. In: JORNADAS URUGUAYAS DE BUIATRÍA, 43., 2015, PAYSANDÚ, UY.; GIANNEECHINI, E.; MATTO, C. (Ed.). [Trabajos presentados]. Paysandú: Centro Médico Veterinario de Paysandú/Sociedad Uruguaya de Buiatría. p.221-223.| Biblioteca(s): INIA La Estanzuela. |
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| 14. | | DONCEL, B.; GIANNITTI, F.; LEMAIRE, C.; RIET-CORREA, F. Descriptive study of cow culling in dairy herds in Uruguay. (AH-P36). [poster-Animal Health] In: World Buiatrics Congress (WBC), 31 st., Abstract Book, Madrid, Spain, September 4-8, 2022. pp.30-31.| Biblioteca(s): INIA Las Brujas. |
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| 20. | | CAFFARENA, D.; SCHILD, C.; RIET-CORREA, F.; GIANNITTI, F. Estenosis yeyunal congenita en una ternera holstein con sindrome del ternero débil. In: JORNADAS URUGUAYAS DE BUIATRÍA, 43., 2015, PAYSANDÚ, UY.; GIANNEECHINI, E.; MATTO, C. (Ed.). [Trabajos presentados]. Paysandú: Centro Médico Veterinario de Paysandú/Sociedad Uruguaya de Buiatría. p. 224-226.| Biblioteca(s): INIA La Estanzuela. |
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| Registros recuperados : 183 | |
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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha actual : |
29/07/2022 |
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Actualizado : |
02/09/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
GIANNITTI, F.; ARÁOZ, V.; SILVEIRA, C.S.; FRANCIA, M.E.; ROBELLO, C.; CABRERA, A. |
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Afiliación : |
FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; VIRGINIA ARÁOZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CAROLINE DA SILVA SILVEIRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MARÍA E. FRANCIA, Laboratorio de Biología de Apicomplejos, Institut Pasteur de Montevideo, Montevideo, Uruguay; Departamento de Parasitología y Micología, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.; CARLOS ROBELLO, Laboratorio de Interacciones Hospedero-Patógeno, Instituto Pasteur de Montevideo, Montevideo, Uruguay; Departamento de Bioquímica, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.; ANDRÉS CABRERA, Laboratorio de Interacciones Hospedero-Patógeno, Instituto Pasteur de Montevideo, Montevideo, Uruguay; Unidad de Microbiología, Departamento de Patobiología, Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay. |
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Título : |
A Holstein heifer infected with Neospora caninum NcUru3 congenitally transmits this strain to a viable offspring although infection does not protect her from aborting by a different N. caninum genotype in the subsequent gestation. |
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Fecha de publicación : |
2022 |
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Fuente / Imprenta : |
Frontiers in Veterinary Science, 2022; 9: 889157. OPEN ACCESS. Doi: https://doi.org/10.3389/fvets.2022.889157 |
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DOI : |
10.3389/fvets.2022.889157 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 03 March 2022/Accepted 05 July 2022/Published 25 July 2022. |
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Contenido : |
Abstract: Neospora caninum is a leading cause of bovine abortion worldwide. Although the genetic diversity of this apicomplexan parasite has long been recognized, there is little information on whether infection with different genotypes results in different clinical outcomes or whether infection by a given genotype impairs protective immunity against abortion induced by different genotypes. Here, we provide evidence supporting that natural subclinical infection with isolate NcUru3 of N. caninum in a pregnant heifer did not provide protection against abortion caused by a different N. caninum genotype in the subsequent gestation. A Holstein heifer delivered a healthy calf congenitally infected with N. caninum. Specific anti-N. caninum IgG was detected by indirect ELISA in sera obtained from the dam at calving and the calf before ingestion of colostrum, indicating in utero exposure to the parasite in the latter. A N. caninum strain named NcUru3 was isolated and characterized by multilocus microsatellite typing from the brain of this neonate euthanized at 9 days of age. Sixty days after calving, the cow got pregnant, although she aborted spontaneously at ~6 months of gestation. Pathologic examination of the aborted fetus and placenta revealed typical lesions of neosporosis, including encephalitis, myocarditis, hepatitis, myositis, and placentitis. Neospora caninum DNA was amplified from the fetal brain, heart, kidney, and placenta, and multilocus microsatellite typing revealed a genotype that differed from isolate NcUru3 at the level of microsatellite marker 6A (MS6A). Serum obtained from the dam at the time of abortion had IgG that cross-recognized isolate NcUru3, as demonstrated by immunoblotting, indicating that the humoral immune response did not prevent the other genotype from infecting the fetus and inducing fetoplacental lesions and abortion. This is the first description of one same dam transmitting two N. caninum genotypes to her offspring in subsequent gestations. MenosAbstract: Neospora caninum is a leading cause of bovine abortion worldwide. Although the genetic diversity of this apicomplexan parasite has long been recognized, there is little information on whether infection with different genotypes results in different clinical outcomes or whether infection by a given genotype impairs protective immunity against abortion induced by different genotypes. Here, we provide evidence supporting that natural subclinical infection with isolate NcUru3 of N. caninum in a pregnant heifer did not provide protection against abortion caused by a different N. caninum genotype in the subsequent gestation. A Holstein heifer delivered a healthy calf congenitally infected with N. caninum. Specific anti-N. caninum IgG was detected by indirect ELISA in sera obtained from the dam at calving and the calf before ingestion of colostrum, indicating in utero exposure to the parasite in the latter. A N. caninum strain named NcUru3 was isolated and characterized by multilocus microsatellite typing from the brain of this neonate euthanized at 9 days of age. Sixty days after calving, the cow got pregnant, although she aborted spontaneously at ~6 months of gestation. Pathologic examination of the aborted fetus and placenta revealed typical lesions of neosporosis, including encephalitis, myocarditis, hepatitis, myositis, and placentitis. Neospora caninum DNA was amplified from the fetal brain, heart, kidney, and placenta, and multilocus microsatellite typing revealed a... Presentar Todo |
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Palabras claves : |
ABORTION; DAIRY CATTLE; GENETIC DIVERSITY; Molecular epidemiology; Multilocus microsatellite typin; Neospora caninum; PATHOLOGY; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL; PLATAFORMA DE SALUD ANIMAL; REPRODUCTIVE DISEASES. |
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Asunto categoría : |
-- |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16659/1/fvets-09-889157.pdf
https://www.frontiersin.org/articles/10.3389/fvets.2022.889157/full
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Marc : |
LEADER 03260naa a2200325 a 4500
001 1063470
005 2022-09-02
008 2022 bl uuuu u00u1 u #d
024 7 $a10.3389/fvets.2022.889157$2DOI
100 1 $aGIANNITTI, F.
245 $aA Holstein heifer infected with Neospora caninum NcUru3 congenitally transmits this strain to a viable offspring although infection does not protect her from aborting by a different N. caninum genotype in the subsequent gestation.$h[electronic resource]
260 $c2022
500 $aArticle history: Received 03 March 2022/Accepted 05 July 2022/Published 25 July 2022.
520 $aAbstract: Neospora caninum is a leading cause of bovine abortion worldwide. Although the genetic diversity of this apicomplexan parasite has long been recognized, there is little information on whether infection with different genotypes results in different clinical outcomes or whether infection by a given genotype impairs protective immunity against abortion induced by different genotypes. Here, we provide evidence supporting that natural subclinical infection with isolate NcUru3 of N. caninum in a pregnant heifer did not provide protection against abortion caused by a different N. caninum genotype in the subsequent gestation. A Holstein heifer delivered a healthy calf congenitally infected with N. caninum. Specific anti-N. caninum IgG was detected by indirect ELISA in sera obtained from the dam at calving and the calf before ingestion of colostrum, indicating in utero exposure to the parasite in the latter. A N. caninum strain named NcUru3 was isolated and characterized by multilocus microsatellite typing from the brain of this neonate euthanized at 9 days of age. Sixty days after calving, the cow got pregnant, although she aborted spontaneously at ~6 months of gestation. Pathologic examination of the aborted fetus and placenta revealed typical lesions of neosporosis, including encephalitis, myocarditis, hepatitis, myositis, and placentitis. Neospora caninum DNA was amplified from the fetal brain, heart, kidney, and placenta, and multilocus microsatellite typing revealed a genotype that differed from isolate NcUru3 at the level of microsatellite marker 6A (MS6A). Serum obtained from the dam at the time of abortion had IgG that cross-recognized isolate NcUru3, as demonstrated by immunoblotting, indicating that the humoral immune response did not prevent the other genotype from infecting the fetus and inducing fetoplacental lesions and abortion. This is the first description of one same dam transmitting two N. caninum genotypes to her offspring in subsequent gestations.
653 $aABORTION
653 $aDAIRY CATTLE
653 $aGENETIC DIVERSITY
653 $aMolecular epidemiology
653 $aMultilocus microsatellite typin
653 $aNeospora caninum
653 $aPATHOLOGY
653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL
653 $aPLATAFORMA DE SALUD ANIMAL
653 $aREPRODUCTIVE DISEASES
700 1 $aARÁOZ, V.
700 1 $aSILVEIRA, C.S.
700 1 $aFRANCIA, M.E.
700 1 $aROBELLO, C.
700 1 $aCABRERA, A.
773 $tFrontiers in Veterinary Science, 2022; 9: 889157. OPEN ACCESS. Doi: https://doi.org/10.3389/fvets.2022.889157
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