|
|
Registros recuperados : 164 | |
66. | | OLIVERA, L.; TELLECHEA, G.; LA MANNA, A.; BANCHERO, G.; FERNANDEZ, E.; RODRÍGUEZ, E.N. Diagnóstico y cuantificación de la problemática causada por la concentración de aves en un tambo estabulado de Uruguay.[Diagnosis and quantification of problems caused by bird concentration: case study in a confined dairy].
farm in Uruguay Revista Argentina de Producción Animal, vol 40, issue 2, pages 85-97, 2020. Article history: Recibido: diciembre 2019/ Aceptado: diciembre 2020.Biblioteca(s): INIA La Estanzuela. |
| |
68. | | AGUILAR, I.; FERNÁNDEZ, E.N.; BLASCO, A.; RAVAGNOLO, O.; LEGARRA, A. Effects of ignoring inbreeding in model-based accuracy for BLUP and SSGBLUP. Journal of Animal Breeding and Genetics, 1 July 2020, Volume 137, Issue 4, pp. 356-364. Doi: https://doi.org/10.1111/jbg.12470 Article history: Received: 22 August 2019 / Revised: 10 December 2019 / Accepted: 11 January 2020 / First published:20 February 2020
Corresponding author: Aguilar, I.; email:iaguilar@inia.org.uy
Funding information: FEDER; INRA;...Biblioteca(s): INIA Las Brujas. |
| |
72. | | BALDI, F.; BANCHERO, G.; LA MANNA, A.; FERNANDEZ, E.; PEREZ, E. Efecto del manejo nutricional post-destete y durante el período de terminación sobre las características de crecimiento y eficiencia de conversión en sistemas de recría y engorde intensivo. ln: INIA LA ESTANZUELA. Jornada de Invernada Intensiva, julio, La Estanzuela, Colonia, Uruguay, 2010. Producción de carne desde una invernada de precisión. La Estanzuela, Colonia (Uruguay): INIA, 2010. p. 1-13 (INIA Serie Actividades de Difusión ; 609)Biblioteca(s): INIA Tacuarembó. |
| |
74. | | LA MANNA, A.; TIERI, M.; FERNANDEZ, E.; MIERES, J.; PEREZ, E.; AGUILAR, I.; BANCHERO, G. Efecto del nivel de proteína y sustitución por urea durante la recría a corral : 3 desempeño posterior a pastoreo. In: CONGRESO ARGENTINO DE PRODUCCIÓN ANIMAL, 34.; JOINT MEETING AAPA-ASAS, 1., 2011, Mar del Plata. Resúmenes. Mar del Plata: ASAS/AAPA, 2011. Revista Argentina de Producción Animal, v. 31,suppl.1. p.355, 2011.Biblioteca(s): INIA La Estanzuela. |
| |
76. | | LA MANNA, A.; BANCHERO, G.; FERNANDEZ, E.; MIERES, J.; TIERI, M.; PÉREZ, E. Efecto de la suplementación infrecuente y de dos niveles de expeler de girasol en el desempeño de novillos de sobreaño pastoreando un rastrojo de sorgo cosechado para grano húmedo ln: INIA LA ESTANZUELA. Jornada de Invernada Intensiva, julio, La Estanzuela, Colonia, Uruguay, 2010. Producción de carne desde una invernada de precisión. La Estanzuela, Colonia (Uruguay): INIA, 2010. p. 43-44 (INIA Serie Actividades de Difusión ; 609) INIA La EstanzuelaBiblioteca(s): INIA Tacuarembó. |
| |
77. | | TIERI, M.; LA MANNA, A.; FERNANDEZ, E.; MIERES, J.; SCROEDER, F.; PEREZ, E.; BANCHERO, G. Efecto de tres niveles de proteína y sustitución de proteína verdadera por urea en la perfomance de terneros cruza en dietas isoenergéticas : 1.
Estudio a corral. In: CONGRESO ARGENTINO DE PRODUCCIÓN ANIMAL, 33. APA-ASAS, 1., 2010,Comarca Viedma, Patagones: ASAS/AAPA, 2010. Revista Argentina de Producción Animal, v. 30 supl 1 , p. 542-543, 2010.Biblioteca(s): INIA La Estanzuela. |
| |
78. | | TIERI, M.; LA MANNA, A.; FERNANDEZ, E.; MIERES, J.; SCROEDER, F.; PEREZ, E.; BANCHERO, G. Efecto de tres niveles de proteína y sustitución de proteína verdadera por urea en la perfomance de terneros cruza en dietas isoenergéticas : 2. Ensayo en jaulas In: CONGRESO ARGENTINO DE PRODUCCIÓN ANIMAL, 33. APA-ASAS, 1., 2010, Comarca Viedma, Patagones: ASAS/AAPA, 2010. Revista Argentina de Producción Animal, v. 30 supl 1 , p. 544-545, 2010.Biblioteca(s): INIA La Estanzuela. |
| |
Registros recuperados : 164 | |
|
|
| Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
Registro completo
|
Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
16/03/2020 |
Actualizado : |
10/08/2020 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
AGUILAR, I.; FERNÁNDEZ, E.N.; BLASCO, A.; RAVAGNOLO, O.; LEGARRA, A. |
Afiliación : |
IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; EDUARDO N. FERNÁNDEZ, Cátedra de Mejora y Conservación de Recursos Genéticos e Instituto de Investigación sobre Producción Agropecuaria, Ambiente y Salud, Facultad de Ciencias Agrarias, UNLZ, Buenos Aires, Argentina; AGUSTÍN BLASCO, Institute for Animal Science and Technology, Universitat Politècnica de València, València, Spain; OLGA RAVAGNOLO GUMILA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDRÉS LEGARRA, UMR GenPhySE, INRA Toulouse, Castanet Tolosan, France. |
Título : |
Effects of ignoring inbreeding in model-based accuracy for BLUP and SSGBLUP. |
Fecha de publicación : |
2020 |
Fuente / Imprenta : |
Journal of Animal Breeding and Genetics, 1 July 2020, Volume 137, Issue 4, pp. 356-364. Doi: https://doi.org/10.1111/jbg.12470 |
ISSN : |
0931-2668 |
DOI : |
10.1111/jbg.12470 |
Idioma : |
Inglés |
Notas : |
Article history: Received: 22 August 2019 / Revised: 10 December 2019 / Accepted: 11 January 2020 / First published:20 February 2020
Corresponding author: Aguilar, I.; email:iaguilar@inia.org.uy
Funding information: FEDER; INRA; Universidad Nacional de Lomas de Zamora; European Unions' Horizon 2020 Research & Innovation Programme, Grant/Award Number: N°772787 |
Contenido : |
ABSTRACT.
Model-based accuracy, defined as the theoretical correlation between true and estimated breeding value, can be obtained for each individual as a function of its prediction error variance (PEV) and inbreeding coefficient F, in BLUP, GBLUP and SSGBLUP genetic evaluations. However, for computational convenience, inbreeding is often ignored in two places. First, in the computation of reliability = 1-PEV/(1 + F). Second, in the set-up, using Henderson's rules, of the inverse of the pedigree-based relationship matrix A. Both approximations have an effect in the computation of model-based accuracy and result in wrong values. In this work, first we present a reminder of the theory and extend it to SSGBLUP. Second, we quantify the error of ignoring inbreeding with real data in three scenarios: BLUP evaluation and SSGBLUP in Uruguayan dairy cattle, and BLUP evaluations in a line of rabbit closed for >40 generations with steady increase of inbreeding up to an average of 0.30. We show that ignoring inbreeding in the set-up of the A-inverse is equivalent to assume that non-inbred animals are actually inbred. This results in an increase of apparent PEV that is negligible for dairy cattle but considerable for rabbit. Ignoring inbreeding in reliability = 1-PEV/(1 + F) leads to underestimation of reliability for BLUP evaluations, and this underestimation is very large for rabbit. For SSGBLUP in dairy cattle, it leads to both underestimation and overestimation of reliability, both for genotyped and non-genotyped animals. We strongly recommend to include inbreeding both in the set-up of A-inverse and in the computation of reliability from PEVs.
© 2020 Blackwell Verlag GmbH MenosABSTRACT.
Model-based accuracy, defined as the theoretical correlation between true and estimated breeding value, can be obtained for each individual as a function of its prediction error variance (PEV) and inbreeding coefficient F, in BLUP, GBLUP and SSGBLUP genetic evaluations. However, for computational convenience, inbreeding is often ignored in two places. First, in the computation of reliability = 1-PEV/(1 + F). Second, in the set-up, using Henderson's rules, of the inverse of the pedigree-based relationship matrix A. Both approximations have an effect in the computation of model-based accuracy and result in wrong values. In this work, first we present a reminder of the theory and extend it to SSGBLUP. Second, we quantify the error of ignoring inbreeding with real data in three scenarios: BLUP evaluation and SSGBLUP in Uruguayan dairy cattle, and BLUP evaluations in a line of rabbit closed for >40 generations with steady increase of inbreeding up to an average of 0.30. We show that ignoring inbreeding in the set-up of the A-inverse is equivalent to assume that non-inbred animals are actually inbred. This results in an increase of apparent PEV that is negligible for dairy cattle but considerable for rabbit. Ignoring inbreeding in reliability = 1-PEV/(1 + F) leads to underestimation of reliability for BLUP evaluations, and this underestimation is very large for rabbit. For SSGBLUP in dairy cattle, it leads to both underestimation and overestimation of reliability, both f... Presentar Todo |
Palabras claves : |
BREEDING; Genomic predictions; GENOMICS. |
Asunto categoría : |
L10 Genética y mejoramiento animal |
Marc : |
LEADER 02789naa a2200241 a 4500 001 1060921 005 2020-08-10 008 2020 bl uuuu u00u1 u #d 022 $a0931-2668 024 7 $a10.1111/jbg.12470$2DOI 100 1 $aAGUILAR, I. 245 $aEffects of ignoring inbreeding in model-based accuracy for BLUP and SSGBLUP.$h[electronic resource] 260 $c2020 500 $aArticle history: Received: 22 August 2019 / Revised: 10 December 2019 / Accepted: 11 January 2020 / First published:20 February 2020 Corresponding author: Aguilar, I.; email:iaguilar@inia.org.uy Funding information: FEDER; INRA; Universidad Nacional de Lomas de Zamora; European Unions' Horizon 2020 Research & Innovation Programme, Grant/Award Number: N°772787 520 $aABSTRACT. Model-based accuracy, defined as the theoretical correlation between true and estimated breeding value, can be obtained for each individual as a function of its prediction error variance (PEV) and inbreeding coefficient F, in BLUP, GBLUP and SSGBLUP genetic evaluations. However, for computational convenience, inbreeding is often ignored in two places. First, in the computation of reliability = 1-PEV/(1 + F). Second, in the set-up, using Henderson's rules, of the inverse of the pedigree-based relationship matrix A. Both approximations have an effect in the computation of model-based accuracy and result in wrong values. In this work, first we present a reminder of the theory and extend it to SSGBLUP. Second, we quantify the error of ignoring inbreeding with real data in three scenarios: BLUP evaluation and SSGBLUP in Uruguayan dairy cattle, and BLUP evaluations in a line of rabbit closed for >40 generations with steady increase of inbreeding up to an average of 0.30. We show that ignoring inbreeding in the set-up of the A-inverse is equivalent to assume that non-inbred animals are actually inbred. This results in an increase of apparent PEV that is negligible for dairy cattle but considerable for rabbit. Ignoring inbreeding in reliability = 1-PEV/(1 + F) leads to underestimation of reliability for BLUP evaluations, and this underestimation is very large for rabbit. For SSGBLUP in dairy cattle, it leads to both underestimation and overestimation of reliability, both for genotyped and non-genotyped animals. We strongly recommend to include inbreeding both in the set-up of A-inverse and in the computation of reliability from PEVs. © 2020 Blackwell Verlag GmbH 653 $aBREEDING 653 $aGenomic predictions 653 $aGENOMICS 700 1 $aFERNÁNDEZ, E.N. 700 1 $aBLASCO, A. 700 1 $aRAVAGNOLO, O. 700 1 $aLEGARRA, A. 773 $tJournal of Animal Breeding and Genetics, 1 July 2020, Volume 137, Issue 4, pp. 356-364. Doi: https://doi.org/10.1111/jbg.12470
Descargar
Esconder MarcPresentar Marc Completo |
Registro original : |
INIA Las Brujas (LB) |
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
Expresión de búsqueda válido. Check! |
|
|