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Registros recuperados : 193 | |
162. | | CASTRO, M.; JORGE, C.; LABORDA, A.; SIMÓ, M.; DIAS, M.; MIGUEL, L.; LORIER, E.; LISTRE, A.; ZERBINO, M.S. Diversidad de la araneofauna en praderas del centro-sur de Uruguay. ln: CONGRESO URUGUAYO DE ZOOLOGÍA, 1., JORNADAS DE ZOOLOGÍA DEL URUGUAY "PROF. FEDERICO ACHÁVAL", 10., 2010, Montevideo, UY. Presentaciones orales: I. Montevideo: SZU, 2010. p. 81.Biblioteca(s): INIA La Estanzuela. |
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164. | | MACHADO, M.; OLIVEIRA, L.G.S.; SCHILD, C.; BOABAID, F.; LUCAS, M.; BURONI, F.; CASTRO, M. B.; RIET-CORREA, F. Lantana camara poisoning in cattle that took refuge during a storm in a forest invaded by this plant. Toxicon, 2023, Volume 229, article 107124. https://doi.org/10.1016/j.toxicon.2023.107124 Article history: Received 8 March 2023; Received in revised form 7 April 2023; Accepted 10 April 2023; Available online 11 April 2023. -- Corresponding author: Riet-Correa, F.; Instituto Nacional de Investigación Agropecuaria, Plataforma...Biblioteca(s): INIA Las Brujas. |
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165. | | CASTRO, M.; PETERSON, C.J.; DALLA RIZZA, M.; DÍAZ DELLA VALLE, P.; VÁZQUEZ, D.; IBAÑEZ, W.; ROSS, A. Influence of heat stress on wheat grain characteristics and protein molecular weight distribution. ln: International Wheat Conference, 7., 27 Nov-2 Dec 2005, Mar del Plata, AR Buck, H.T.; Nisi, J.E.; Salomón, N., ed. Wheat production in stressed environments : proceedings. Dordrecht: Springer, 2007. p. 365-371. (Developments in Plant Breeding ; 12)Biblioteca(s): INIA La Estanzuela. |
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166. | | MACHADO, M.; CASTRO, M.B.; WILSON, T. M.; GONÇALVES , A. A. B.; PORTIANSKY, E.; RIET-CORREA, F.; BARROS, S. S. Poisoning by Nierembergia veitchii: Effects on vascular smooth muscle cells in the pathogenesis of enzootic calcinosis. Veterinary Pathology, 2022, Volume 59, Issue 5, pages 814-823. doi: https://doi.org/10.1177/03009858221098430 Article history: Article first published online May 19, 2022; Published online September 2022. -- Corresponding Author: Franklin Riet-Correa, Postgraduate Program in Animal Science in the Tropics, School of Veterinary Medicine and Animal...Biblioteca(s): INIA Las Brujas. |
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168. | | GERMAN, S.; PEREYRA, S.; CASTRO, M.; AZZIMONTI, G.; QUINCKE, M.; KOHLI, M.; MADARIAGA, R.; CHAVES , M.; CAMPO, P. Las royas del trigo: situación a nivel regional y amenazas para el cultivo. In: CONGRESO NACIONAL DE TRIGO, 8o. ; SIMPOSIO DE CEREALES DE SIEMBRA OTOÑO INVERNAL, 6o. ; ENCUENTRO DEL MERCOSUR, 2º, Pergamino, Argentina: AIANBA, 14-16 setiembre,2016.Biblioteca(s): INIA La Estanzuela. |
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170. | | CASTRO, M.; GASO, D.; VÁZQUEZ, D.; PIRELLI, J.; BERGER, A.G.; CALISTRO, R.; VERA, M.; VIEGA, L.; OTERO, A. Variabilidad genotípica en la tolerancia al anegamiento en cebada (Hordeum vulgare L.). In: CONGRESO LATINOAMERICANO DE CEBADA, 4., 2013, Bahía Blanca, AR. Resúmenes. Bahía Blanca: Bolsa de Cereales y Productos, 2013.Biblioteca(s): INIA La Estanzuela. |
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171. | | BRANDARIZ, S.P.; GONZÁELZ-REYMÚNDEZ, A.; LADO, B.; QUINCKE, M.; VON ZITZEWITZ, J.; CASTRO, M.; MATUS, I.; DEL POZO, A.; GUTIÉRREZ, L. Effect of using imputed missing data on QTL detection on a wheat GWAS panel. In: SEMINARIO INTERNACIONAL DE TRIGO, 2014, La Estanzuela, Colonia, UY. GERMÁN, S., et al. (Org.). 1914-2014, un siglo de mejoramiento de trigo en La Estanzuela: un valioso legado para el futuro: posters; resúmenes. La Estanzuela, Colonia, UY: INIA, 2014. p. 86.Biblioteca(s): INIA La Estanzuela. |
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172. | | BRANDARIZ, S.P.; GONZÁLEZ-REYMÚNDEZ, A.; LADO, B.; QUINCKE, M.; VON ZITZEWITZ, J.; CASTRO, M.; MATUS, I.; DEL POZO, A.; GUTIÉRREZ , L. Effect of using imputed missing data on QTL detection on a wheat GWAS panel. [Poster]. In: German, S.; Quincke, M.; Vázquez, D.; Castro, M.; Pereyra, S.; Silva, P.; García, A. (Eds.). Seminario Internacional "1914-2014: Un siglo de mejoramiento de trigo en La Estanzuela". Montevideo (UY): INIA, 2018. p. 304. (INIA Serie Técnica; 241).Biblioteca(s): INIA La Estanzuela. |
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173. | | SOUSA, A.L.V.; SOUSA, D.E.R.; CERQUEIRA, L.A.; QUEIROZ-MACHADO, C.R.R.; GIARETTA, P.R.; RIET-CORREA, F.; CASTRO, M.B.; MACHADO, M. Cestrum axillare hepatotoxicity in cattle in the Distrito Federal, Goiás and Minas Gerais. [Hepatotoxicidade do Cestrum axillare em bovinos do Distrito Federal, Goiás e Minas Gerais].. Original Article. Livestock Diseases. Pesquisa Veterinaria Brasileira. 2024, Volume 44, e07399. https://doi.org/10.1590/1678-5150-PVB-7399 -- OPEN ACCESS. Article history: Received 08 Nov 2023, Accepted 09 Dec 2023, Publication in this collection 18 Mar 2024, Date of issue 2024. -- Correspondence: Machado, M.; Graduate Program in Animal Science, Faculdade de Agronomia e Medicina...Biblioteca(s): INIA Las Brujas. |
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174. | | CURIN, F.; BALMACEDA, M.; BRACH, A.; CASTRO, M.; KAVANOVÁ, M.; OTERO, A.; ROSETTI, L.; RUIZ, M.; ALFARO, C.; QUINCKE, A.; ZUIL, S.; GONZÁLEZ, F.G. Evaluación de cultivares de trigo contrastantes para tolerancia a deficit hídrico en un amplio rango de ambientes en el cono sur de America. In: IX Congreso Nacional de Calidad de Trigo, 9°; VII Simposio de Cereales de siembra otoño-invernal; III Reunión del Mercosur, 29-30 setiembre 2021, tres arroyos, Provincia de Buenos Aires, Argentina: La Chacra Experimental Integrada Barrow, Instituto Nacional de Tecnología Agropecuaria (INTA), Centro Regional de Ingenieros Agrónomos de Tres Arroyos (CRIATA), Centro Regional de Estudios Superiores de Tres Arroyos (CRESTA).Modalidad Virtual.Biblioteca(s): INIA La Estanzuela. |
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175. | | ALZUGARAY, R.; BAO, L.; CASCO, M.; CASTRO, M.; CUITIÑO, M.J.; GONZÁLEZ, S.N.; PLA, M.; REBUFFO, M.; RIBEIRO, A.; ZARZA, R. Estrategias recomendadas para mejorar la implantación de leguminosas forrajeras. In:REUNIÓN TÉCNICA (2013, LA ESTANZUELA, COLONIA, UY): el éxito productivo de una pastura con leguminosas perennes comienza en su implantación.La Estanzuela, Colonia: INIA, 2013. p. 43-44. (Serie Actividades de Difusión ; 711).Biblioteca(s): INIA La Estanzuela. |
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176. | | MACÊDO, I.L. DE; SOUSA, D.E.R. DE; SOUZA, A.D.R.; ARMIÉN, A.G.; MACHADO, M.; CASTRO, M.B. DE Fatal Africanized bee attack in captive non-human primates (Saimiri ustus and Sapajus libidinosus). Short communication. Toxicon. 2024, Volume 241, Article 107666. https://doi.org/10.1016/j.toxicon.2024.107666 Article history: Received 8 February 2024, Revised 26 February 2024, Accepted 27 February 2024, Available online 28 February 2024, Version of Record 8 March 2024. -- Correspondence: Castro, M.B.D.; Veterinary Pathology and Forensic...Biblioteca(s): INIA Las Brujas. |
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177. | | LADO, B.; POLAND, J.; BELZILE, F.; DEL POZO, A.; MATUS, I.; RODRÍGUEZ, A.; INOSTROZA, L.; LOBOS, G.A.; CASTRO, M.; QUINCKE, M.; LANDECHEA, L.; VON ZITZEWITZ, J. Genotipado por secuenciación del genoma de 384 genotipos de T. aestivum para selección genómica. BAG. Journal of Basic and Applied Genetics ,Ciudad Autónoma de Buenos Aires, v.23, supl.1, p. 267, 2012.Biblioteca(s): INIA La Estanzuela. |
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178. | | MACHADO, M.; QUEIROZ-MACHADO, C.R.R.; GARDNER, D.R.; CASTRO, M.B.; CÂMARA, A.C.L.; PIMENTEL, L.A.; GALIZA, G.J.N.; RIET-CORREA, F. Leucaena leucocephala toxicity in Brazilian horses. Toxicon. 2024, Volume 240, Article 107655. https://doi.org/10.1016/j.toxicon.2024.107655 Article history: Received 10 January 2024; Received in revised form 16 February 2024; Accepted 18 February 2024; Available online 19 February 2024. -- Correspondence: Machado, M.; Plataforma de Investigación en Salud Animal (PSA),...Biblioteca(s): INIA Las Brujas. |
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179. | | MACHADO, M.; QUEIROZ, CINTIA R.R.; WILSON, T. M.; SOUSA, D.E.R.; SOTO-BLANCO, B.; ARMIÉN, A.G.; BARROS, S.S.; RIET-CORREA, F.; CASTRO, M.B. Neurological and gastrointestinal manifestations of spontaneous poisoning by Ricinus communis in goats. Toxicon, July 2022, vol. 214, pages 74-77. doi: https://doi.org/10.1016/j.toxicon.2022.05.004 Article history: Received 20 April 2022; Received in revised form 4 May 2022; Accepted 13 May 2022; Available online 20 May 2022.
Corresponding author: Machado, M.; Instituto Nacional de Investigación Agropecuaria, Plataforma de Salud...Biblioteca(s): INIA Las Brujas. |
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180. | | LADO, B.; MATUS, I.; RODRIGUEZ, A.; INOSTROZA, L.; POLAND, J.; BELZILE ,F.; DEL POZO, A.; QUINCKE, M.; CASTRO, M.; VON ZITZEWITZ, J. Increased genomic prediction accuracy in wheat breeding through spatial adjustment of field trial data. G3: Genes, Genomes, Genetics (Bethesda), v. 3, n,12, p. 2105-2114, 2013.OPEN ACCESS. Article history: Received 2013 Aug 26 // Accepted 2013 Sep 18.Biblioteca(s): INIA La Estanzuela. |
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Registros recuperados : 193 | |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
07/06/2022 |
Actualizado : |
30/11/2022 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
MACHADO, M.; CASTRO, M.B.; WILSON, T. M.; GONÇALVES , A. A. B.; PORTIANSKY, E.; RIET-CORREA, F.; BARROS, S. S. |
Afiliación : |
MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MÁRCIO B. CASTRO, University of Brasilia, Brasília, Brazil; TAIS M. WILSON, University of Brasilia, Brasília, Brazil; ALEXANDRA A. B. GONÇALVES, University of Brasilia, Brasília, Brazil; ENRIQUE L. PORTIANSKY, National University of La Plata, La Plata, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Federal University of Bahia, Salvador, Brazil; SEVERO S. BARROS, Federal University of Santa Maria, Rio Grande do Sul, Brazil. |
Título : |
Poisoning by Nierembergia veitchii: Effects on vascular smooth muscle cells in the pathogenesis of enzootic calcinosis. |
Fecha de publicación : |
2022 |
Fuente / Imprenta : |
Veterinary Pathology, 2022, Volume 59, Issue 5, pages 814-823. doi: https://doi.org/10.1177/03009858221098430 |
ISSN : |
0300-9858 |
DOI : |
10.1177/03009858221098430 |
Idioma : |
Inglés |
Notas : |
Article history: Article first published online May 19, 2022; Published online September 2022. -- Corresponding Author: Franklin Riet-Correa, Postgraduate Program in Animal Science in the Tropics, School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Bahia 40170-110, Brazil. Email: franklinrietcorrea@gmail.com -- This work was funded by National Institute of Agricultural Research (INIA) of Uruguay (Project CL 44), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil, (Finance Code 001) and National University of La Plata (Project V270). A postgraduate scholarship was provided to Mizael Machado by INIA, Uruguay. |
Contenido : |
ABSTRACT - Vascular mineralization is a hallmark of enzootic calcinosis. Histopathological, ultrastructural, and immunohistochemical investigations were performed on the external carotid arteries of seven sheep naturally poisoned by Nierembergia veitchii. Histologically, moderate to marked hyperplasia of the tunica intima was observed without mineralization. The tunica media exhibited mild to severe mineralization and osteochondroid metaplasia. Sheep with enzootic calcinosis showed arterial overexpression of osteopontin and tissue-nonspecific alkaline phosphatase and immunolabeling for osteonectin and osteocalcin in both intima and media layers of the tested arteries. The main ultrastructural finding in the tunica media was a marked phenotypic change of vascular smooth muscle cells from a contractile phenotype (VSMC-C) into a synthetic phenotype (VSMC-S). In the tunica media, VSMC-S produced matrix and extracellular vesicles, forming mineralizable granules associated with arterial mineralization. VSMC-S were also present in the tunica intima, but matrix and extracellular vesicles and mineralization were not observed. The absence of matrix and extracellular vesicles in the intimal hyperplasia, even in the presence of noncollagenous bone proteins, tissue-nonspecific alkaline phosphatase, and vitamin D receptors, reinforces the hypothesis that the presence of matrix and extracellular vesicles are crucial for the development of vascular mineralization in enzootic calcinosis. It is proposed that the two different VSMC-S phenotypes in calcinosis are due to the expression of at least two genetically different types of these cells induced by the action of 1,25(OH)2D3. © The Author(s) 2022. MenosABSTRACT - Vascular mineralization is a hallmark of enzootic calcinosis. Histopathological, ultrastructural, and immunohistochemical investigations were performed on the external carotid arteries of seven sheep naturally poisoned by Nierembergia veitchii. Histologically, moderate to marked hyperplasia of the tunica intima was observed without mineralization. The tunica media exhibited mild to severe mineralization and osteochondroid metaplasia. Sheep with enzootic calcinosis showed arterial overexpression of osteopontin and tissue-nonspecific alkaline phosphatase and immunolabeling for osteonectin and osteocalcin in both intima and media layers of the tested arteries. The main ultrastructural finding in the tunica media was a marked phenotypic change of vascular smooth muscle cells from a contractile phenotype (VSMC-C) into a synthetic phenotype (VSMC-S). In the tunica media, VSMC-S produced matrix and extracellular vesicles, forming mineralizable granules associated with arterial mineralization. VSMC-S were also present in the tunica intima, but matrix and extracellular vesicles and mineralization were not observed. The absence of matrix and extracellular vesicles in the intimal hyperplasia, even in the presence of noncollagenous bone proteins, tissue-nonspecific alkaline phosphatase, and vitamin D receptors, reinforces the hypothesis that the presence of matrix and extracellular vesicles are crucial for the development of vascular mineralization in enzootic calcinosis. It ... Presentar Todo |
Palabras claves : |
Arterial mineralization; Arteries; Enzootic calcinosis; Exosomes; Pathogenesis; PLATAFORMA DE SALUD ANIMAL; Toxicity; Vascular smooth muscle cells. |
Asunto categoría : |
L50 Fisiología y bioquímica animal |
Marc : |
LEADER 03391nam a2200313 a 4500 001 1063233 005 2022-11-30 008 2022 bl uuuu u01u1 u #d 022 $a0300-9858 024 7 $a10.1177/03009858221098430$2DOI 100 1 $aMACHADO, M. 245 $aPoisoning by Nierembergia veitchii$bEffects on vascular smooth muscle cells in the pathogenesis of enzootic calcinosis.$h[electronic resource] 260 $aVeterinary Pathology, 2022, Volume 59, Issue 5, pages 814-823. doi: https://doi.org/10.1177/03009858221098430$c1177 500 $aArticle history: Article first published online May 19, 2022; Published online September 2022. -- Corresponding Author: Franklin Riet-Correa, Postgraduate Program in Animal Science in the Tropics, School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Bahia 40170-110, Brazil. Email: franklinrietcorrea@gmail.com -- This work was funded by National Institute of Agricultural Research (INIA) of Uruguay (Project CL 44), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil, (Finance Code 001) and National University of La Plata (Project V270). A postgraduate scholarship was provided to Mizael Machado by INIA, Uruguay. 520 $aABSTRACT - Vascular mineralization is a hallmark of enzootic calcinosis. Histopathological, ultrastructural, and immunohistochemical investigations were performed on the external carotid arteries of seven sheep naturally poisoned by Nierembergia veitchii. Histologically, moderate to marked hyperplasia of the tunica intima was observed without mineralization. The tunica media exhibited mild to severe mineralization and osteochondroid metaplasia. Sheep with enzootic calcinosis showed arterial overexpression of osteopontin and tissue-nonspecific alkaline phosphatase and immunolabeling for osteonectin and osteocalcin in both intima and media layers of the tested arteries. The main ultrastructural finding in the tunica media was a marked phenotypic change of vascular smooth muscle cells from a contractile phenotype (VSMC-C) into a synthetic phenotype (VSMC-S). In the tunica media, VSMC-S produced matrix and extracellular vesicles, forming mineralizable granules associated with arterial mineralization. VSMC-S were also present in the tunica intima, but matrix and extracellular vesicles and mineralization were not observed. The absence of matrix and extracellular vesicles in the intimal hyperplasia, even in the presence of noncollagenous bone proteins, tissue-nonspecific alkaline phosphatase, and vitamin D receptors, reinforces the hypothesis that the presence of matrix and extracellular vesicles are crucial for the development of vascular mineralization in enzootic calcinosis. It is proposed that the two different VSMC-S phenotypes in calcinosis are due to the expression of at least two genetically different types of these cells induced by the action of 1,25(OH)2D3. © The Author(s) 2022. 653 $aArterial mineralization 653 $aArteries 653 $aEnzootic calcinosis 653 $aExosomes 653 $aPathogenesis 653 $aPLATAFORMA DE SALUD ANIMAL 653 $aToxicity 653 $aVascular smooth muscle cells 700 1 $aCASTRO, M.B. 700 1 $aWILSON, T. M. 700 1 $aGONÇALVES , A. A. B. 700 1 $aPORTIANSKY, E. 700 1 $aRIET-CORREA, F. 700 1 $aBARROS, S. S.
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