| |
|
|
| Registros recuperados : 8 | |
| 1. |  | GARCIA-ROCHE, M.; CAÑIBE, G.; TALMÓN, D.; MENDOZA, A.; CASSINA, A.; QUIJANO, C.; CARRIQUIRY, M. Abundancia mitocondrial hepática en dos genotipos holstein en pastoreo. In: Jornadas Uruguayas de Buiatría, 48., 2021. Paysandú, Uruguay: Centro Médico Veterinario de Paysandú; Filial de la Sociedad de Medicina Veterinaria del Uruguaya; Sociedad Uruguaya de Buiatría, 31 de Mayo al 4 de Junio 2021. [Poster]. p.251-253.| Biblioteca(s): INIA La Estanzuela. |
|    |
| 2. | | CASAL, A.; GARCÍA-ROCHE, M.; NAVAJAS, E.; CASSINA, A.; CARRIQUIRY, M Differential hepatic oxidative status in steers with divergent residual feed intake phenotype. Animal, 1 January 2020, Volume 14, Issue 1, Pages 78-85. Doi: https://doi.org/10.1017/S1751731119001332 Article history: Received 12 December 2018 // Accepted 6 May 2019 // Published online: 20 June 2019.
Supplementary materials.
Corresponding author: Casal, A.; Departamento de Produccion Animal y Pasturas, Facultad de Agronomia,...| Biblioteca(s): INIA Las Brujas. |
|  |
| 4. | | GARCÍA-ROCHE, M.; TALMÓN, D.; CAÑIBE, G.; MENDOZA, A.; QUIJANO, C.; CASSINA, A.; CARRIQUIRY, M. Expresión génica hepática de la vía del receptor alfa activado por proliferador de peroxisomas A (PPARA) en dos genotipos Holstein. [abstract]. In: AUPA, Proceedings del VII Congreso Uruguayo de Producción Animal. Sección Cambio Climático y Producción Sostenible (Climate Change Section), 14 y 15 diciembre 2021. Archivos Latinoamericanos de Producción Animal, 29(Supl.1), p.2. (Archivos Latinoamericanos de Producción Animal, Vol.29, Supl.1)| Biblioteca(s): INIA Las Brujas. |
| |
| 5. | | GARCÍA-ROCHE, M.; TALMÓN, D.; CAÑIBE, G.; ASTESSIANO, A.L.; MENDOZA, A.; QUIJANO, C.; CASSINA, A.; CARRIQUIRY, M. Differential hepatic mitochondrial function and gluconeogenic gene expression in 2 Holstein strains in a pasture-based system. Journal of Dairy Science, July 2022, Volume 105, Issue 7, Pages 5723-5737. OPEN ACCESS. doi: https://doi.org/10.3168/jds.2021-21358 Article history: Received 30 September 2021, Accepted 17 March 2022, Available online 20 May 2022, Version of Record 22 June 2022. -- Corresponding author: García-Roche, M.; Departamento de Producción Animal y Pasturas, Facultad de...| Biblioteca(s): INIA La Estanzuela. |
| |
| 6. | | GARCIA ROCHE, M.; TALMÓN, D.; JORGE-SMEDING, E.; CASAL, A.; MENDOZA, A.; QUIJANO, C.; CARRIQUIRY, M; CASSINA, A. Función mitocondrial en biopsias de hígado de vacas lecheras de dos genotipos Holstein en condiciones pastoriles. [Resumen]. En: CONGRESO ASOCIACIÓN URUGUAYA DE PRODUCCIÓN ANIMAL (6º, Marzo, 2018, Tacuarembó, Uruguay). Tacuarembó: AUPA, 2018. p. 34.| Biblioteca(s): INIA La Estanzuela. |
| |
| 7. | | GARCÍA-ROCHE, M.; TALMÓN, D.; CAÑIBE, G.; ASTESSIANO, A.L.; MENDOZA, A.; CASSINA, A.; QUIJANO, C.; CARRIQUIRY, M. Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion. PLoS ONE, October 2023, Volume 18, Issue 10, e0290551. https://doi.org/10.1371/journal.pone.0290551 -- OPEN ACCESS. Article history: Received March 22 2023; Accepted August 9 2023; Published October 26 2023. -- Correspondence: García-Roche, M.; Facultad de Agronomía, Departamento de Producción Animal y Pasturas, Universidad de la República, Montevideo,...| Biblioteca(s): INIA Las Brujas. |
|  |
| 8. | | GARCIA-ROCHE, M.; CAÑIBE, G.; ASTESSIANO, A.; TALMON, D.; MENDOZA, A.; CASSINA, A.; QUIJANO, C.; CARRIQUIRY, M. O14 Hepatic energy reserves and carnitine palmitoyltransferase activity in grazing dairy cows of two pasture-based systems during lactation. [conference abstract] Animal - science proceedings, August 2022, Volume 13, Issue 3, pages 260-261. https://doi.org/10.1016/j.anscip.2022.07.024 Article histrory: Available online 16 September 2022, Version of Record 16 September 2022. -- Funding: MGR was supported by CAP fellowship BDDX_2018_1#49004502. The project was funded by CSIC I+D 2018 ID 103 awarded to MC and CQ and by...| Biblioteca(s): INIA Las Brujas. |
| |
| Registros recuperados : 8 | |
|
|
|
|
Registro completo
|
|
Biblioteca (s) : |
INIA La Estanzuela. |
|
Fecha actual : |
11/07/2022 |
|
Actualizado : |
02/12/2022 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Circulación / Nivel : |
Internacional - -- |
|
Autor : |
GARCÍA-ROCHE, M.; TALMÓN, D.; CAÑIBE, G.; ASTESSIANO, A.L.; MENDOZA, A.; QUIJANO, C.; CASSINA, A.; CARRIQUIRY, M. |
|
Afiliación : |
MERCEDES GARCÍA-ROCHE V, Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, 12900, Montevideo, Uruguay.; DANIEL TALMÓN, Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, 12900, Montevideo, Uruguay.; GUILLERMO CAÑIBE, Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, 12900, Montevideo, Uruguay.; ANA LAURA ASTESSIANO, Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, 12900, Montevideo, Uruguay.; ALEJANDRO FRANCISCO MENDOZA AGUIAR, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CELIA QUIJANO, Centro de Investigaciones Biomédicas (CEINBIO) and Departamento de Bioquímica, Facultad de Medicina, Universidad de la República, 11900, Montevideo, Uruguay.; ADRIANA CASSINA, Centro de Investigaciones Biomédicas (CEINBIO) and Departamento de Bioquímica, Facultad de Medicina, Universidad de la República, 11900, Montevideo, Uruguay.; MARIANA CARRIQUIRY, Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, 12900, Montevideo, Uruguay. |
|
Título : |
Differential hepatic mitochondrial function and gluconeogenic gene expression in 2 Holstein strains in a pasture-based system. |
|
Fecha de publicación : |
2022 |
|
Fuente / Imprenta : |
Journal of Dairy Science, July 2022, Volume 105, Issue 7, Pages 5723-5737. OPEN ACCESS. doi: https://doi.org/10.3168/jds.2021-21358 |
|
ISSN : |
0022-0302 |
|
DOI : |
10.3168/jds.2021-21358 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received 30 September 2021, Accepted 17 March 2022, Available online 20 May 2022, Version of Record 22 June 2022. -- Corresponding author: García-Roche, M.; Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Montevideo, Uruguay; email:mercedesg@fagro.edu.uy -- LICENSE: This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). -- Funding: The authors thank all the staff of the Dairy Unit of the Experimental Station ?La Estanzuela? (Semillero, Uruguay) for their support in animal handling, as well as Ezequiel Jorge-Smeding (Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Montevideo, Uruguay) and Irene Benoit (Centro de Investigaciones Biomédicas and Departamento de Bioquímica, Facultad de Medicina, Universidad de la República, Montevideo) for support in the analysis of blood metabolites. MGR conceived and designed laboratory experiments, performed field and laboratory experiments, analyzed the results, and wrote the original draft and revised versions of the manuscript. MC conceptualized and designed field experiment, conceived and designed laboratory experiments, supervised field and laboratory experiments and results analyses, obtained funding and administrated the project, and reviewed and edited the manuscript. CQ conceived, designed, and supervised laboratory experiments, and reviewed and edited the manuscript. AC conceived, designed, and supervised laboratory experiments. AM conceptualized and designed the field experiment and obtained funding. DT, ALA, and GC performed field and laboratory experiments. All authors reviewed the manuscript and approved the final version of the manuscript. M. García-Roche was supported by Comisión Académica de Posgrados (Montevideo, Uruguay) fellowship BDDX_2018_1#49004502. D. Talmón was supported by Agencia Nacional de Investigación e Innovación (ANII) fellowship POS_NAC_2017_1_141266. A. Cassina and C. Quijano were partially funded by grants of the Espacio Interdisciplinario-Centros, Universidad de la República (UdelaR; Montevideo, Uruguay) 2015. A. Cassina was also supported by the grant Comisión Sectorial de Investigación Científica (CSIC) grupos I+D 2014 (767). The project was funded by CSIC of the UdelaR CSIC I+D 2018 ID 103 to M. Carriquiry and C. Quijano, as well as by ANII INNOVAGRO 2018: FSA_1_2018_1_152220 to M. Carriquiry and A. Cassina. A. Mendoza received funding from the project PL_21_0_00 of the Instituto Nacional de Investigación Agropecuaria (Semillero, Uruguay). The authors have not stated any conflicts of interest. |
|
Contenido : |
ABSTRACT:
The objective of this study was to assess hepatic ATP synthesis in Holstein cows of North American and New Zealand origins and the gluconeogenic pathway, one of the pathways with the highest ATP demands in the ruminant liver. Autumn-calving Holstein cows of New Zealand and North American origins were managed in a pasture-based system with supplementation of concentrate that represented approximately 33% of the predicted dry matter intake during 2017, 2018, and 2019, and hepatic biopsies were taken during mid-lactation at 174 ± 23 days in milk. Cows of both strains produced similar levels of solids-corrected milk, and no differences in body condition score were found. Plasma glucose concentrations were higher for cows of New Zealand versus North American origin. Hepatic mitochondrial function evaluated measuring oxygen consumption rates showed that mitochondrial parameters related to ATP synthesis and maximum respiratory rate were increased for cows of New Zealand compared with North American origin. However, hepatic gene expression of pyruvate carboxylase, phosphoenolpyruvate carboxykinase, and pyruvate dehydrogenase kinase was increased in North American compared with New Zealand cows. These results altogether suggest an increased activity of the tricarboxylic cycle in New Zealand cows, leading to increased ATP synthesis, whereas North American cows pull tricarboxylic cycle intermediates toward gluconeogenesis. The fact that this occurs during mid-lactation could account for the increased persistency of North American cows, especially in a pasture-based system. In addition, we observed an augmented mitochondrial density in New Zealand cows, which could be related to feed efficiency mechanisms. In sum, our results contribute to the elucidation of hepatic molecular mechanisms in dairy cows in production systems with higher inclusion of pastures. © 2022 American Dairy Science Association. MenosABSTRACT:
The objective of this study was to assess hepatic ATP synthesis in Holstein cows of North American and New Zealand origins and the gluconeogenic pathway, one of the pathways with the highest ATP demands in the ruminant liver. Autumn-calving Holstein cows of New Zealand and North American origins were managed in a pasture-based system with supplementation of concentrate that represented approximately 33% of the predicted dry matter intake during 2017, 2018, and 2019, and hepatic biopsies were taken during mid-lactation at 174 ± 23 days in milk. Cows of both strains produced similar levels of solids-corrected milk, and no differences in body condition score were found. Plasma glucose concentrations were higher for cows of New Zealand versus North American origin. Hepatic mitochondrial function evaluated measuring oxygen consumption rates showed that mitochondrial parameters related to ATP synthesis and maximum respiratory rate were increased for cows of New Zealand compared with North American origin. However, hepatic gene expression of pyruvate carboxylase, phosphoenolpyruvate carboxykinase, and pyruvate dehydrogenase kinase was increased in North American compared with New Zealand cows. These results altogether suggest an increased activity of the tricarboxylic cycle in New Zealand cows, leading to increased ATP synthesis, whereas North American cows pull tricarboxylic cycle intermediates toward gluconeogenesis. The fact that this occurs during mid-lactation could ... Presentar Todo |
|
Palabras claves : |
Dairy cows; Gluconeogenesis; Grazing; Holstein-Friesian; Intermediary metabolismg. |
|
Thesagro : |
VACAS LECHERAS. |
|
Asunto categoría : |
-- |
|
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16559/1/J.-Dairy-Sci.-105p.57235737-Mendoza.pdf
|
|
Marc : |
LEADER 05614naa a2200313 a 4500
001 1063411
005 2022-12-02
008 2022 bl uuuu u00u1 u #d
022 $a0022-0302
024 7 $a10.3168/jds.2021-21358$2DOI
100 1 $aGARCÍA-ROCHE, M.
245 $aDifferential hepatic mitochondrial function and gluconeogenic gene expression in 2 Holstein strains in a pasture-based system.$h[electronic resource]
260 $c2022
500 $aArticle history: Received 30 September 2021, Accepted 17 March 2022, Available online 20 May 2022, Version of Record 22 June 2022. -- Corresponding author: García-Roche, M.; Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Montevideo, Uruguay; email:mercedesg@fagro.edu.uy -- LICENSE: This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). -- Funding: The authors thank all the staff of the Dairy Unit of the Experimental Station ?La Estanzuela? (Semillero, Uruguay) for their support in animal handling, as well as Ezequiel Jorge-Smeding (Departamento de Producción Animal y Pasturas, Facultad de Agronomía, Universidad de la República, Montevideo, Uruguay) and Irene Benoit (Centro de Investigaciones Biomédicas and Departamento de Bioquímica, Facultad de Medicina, Universidad de la República, Montevideo) for support in the analysis of blood metabolites. MGR conceived and designed laboratory experiments, performed field and laboratory experiments, analyzed the results, and wrote the original draft and revised versions of the manuscript. MC conceptualized and designed field experiment, conceived and designed laboratory experiments, supervised field and laboratory experiments and results analyses, obtained funding and administrated the project, and reviewed and edited the manuscript. CQ conceived, designed, and supervised laboratory experiments, and reviewed and edited the manuscript. AC conceived, designed, and supervised laboratory experiments. AM conceptualized and designed the field experiment and obtained funding. DT, ALA, and GC performed field and laboratory experiments. All authors reviewed the manuscript and approved the final version of the manuscript. M. García-Roche was supported by Comisión Académica de Posgrados (Montevideo, Uruguay) fellowship BDDX_2018_1#49004502. D. Talmón was supported by Agencia Nacional de Investigación e Innovación (ANII) fellowship POS_NAC_2017_1_141266. A. Cassina and C. Quijano were partially funded by grants of the Espacio Interdisciplinario-Centros, Universidad de la República (UdelaR; Montevideo, Uruguay) 2015. A. Cassina was also supported by the grant Comisión Sectorial de Investigación Científica (CSIC) grupos I+D 2014 (767). The project was funded by CSIC of the UdelaR CSIC I+D 2018 ID 103 to M. Carriquiry and C. Quijano, as well as by ANII INNOVAGRO 2018: FSA_1_2018_1_152220 to M. Carriquiry and A. Cassina. A. Mendoza received funding from the project PL_21_0_00 of the Instituto Nacional de Investigación Agropecuaria (Semillero, Uruguay). The authors have not stated any conflicts of interest.
520 $aABSTRACT: The objective of this study was to assess hepatic ATP synthesis in Holstein cows of North American and New Zealand origins and the gluconeogenic pathway, one of the pathways with the highest ATP demands in the ruminant liver. Autumn-calving Holstein cows of New Zealand and North American origins were managed in a pasture-based system with supplementation of concentrate that represented approximately 33% of the predicted dry matter intake during 2017, 2018, and 2019, and hepatic biopsies were taken during mid-lactation at 174 ± 23 days in milk. Cows of both strains produced similar levels of solids-corrected milk, and no differences in body condition score were found. Plasma glucose concentrations were higher for cows of New Zealand versus North American origin. Hepatic mitochondrial function evaluated measuring oxygen consumption rates showed that mitochondrial parameters related to ATP synthesis and maximum respiratory rate were increased for cows of New Zealand compared with North American origin. However, hepatic gene expression of pyruvate carboxylase, phosphoenolpyruvate carboxykinase, and pyruvate dehydrogenase kinase was increased in North American compared with New Zealand cows. These results altogether suggest an increased activity of the tricarboxylic cycle in New Zealand cows, leading to increased ATP synthesis, whereas North American cows pull tricarboxylic cycle intermediates toward gluconeogenesis. The fact that this occurs during mid-lactation could account for the increased persistency of North American cows, especially in a pasture-based system. In addition, we observed an augmented mitochondrial density in New Zealand cows, which could be related to feed efficiency mechanisms. In sum, our results contribute to the elucidation of hepatic molecular mechanisms in dairy cows in production systems with higher inclusion of pastures. © 2022 American Dairy Science Association.
650 $aVACAS LECHERAS
653 $aDairy cows
653 $aGluconeogenesis
653 $aGrazing
653 $aHolstein-Friesian
653 $aIntermediary metabolismg
700 1 $aTALMÓN, D.
700 1 $aCAÑIBE, G.
700 1 $aASTESSIANO, A.L.
700 1 $aMENDOZA, A.
700 1 $aQUIJANO, C.
700 1 $aCASSINA, A.
700 1 $aCARRIQUIRY, M.
773 $tJournal of Dairy Science, July 2022, Volume 105, Issue 7, Pages 5723-5737. OPEN ACCESS. doi: https://doi.org/10.3168/jds.2021-21358
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA La Estanzuela (LE) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
| Expresión de búsqueda válido. Check! |
|
|
