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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
Fecha : |
19/11/2021 |
Actualizado : |
02/09/2022 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
GAURAV, K.; ARORA, S.; SILVA, P.; SÁNCHEZ-MARTÍN, J.; HORSNELL,R.; GAO, L.; BRAR ,G.S.; WIDRIG,V.; JOHN RAUPP,W.; SINGH, N.; WU, S.; KALE, S.M.; CHINOY, C.; NICHOLSON, P.; QUIROZ-CHÁVEZ, J.; SIMMONDS, J.; HAYTA, S.; SMEDLEY, M. A; HARWOOD, W.; PEARCE, S.; GILBERT, D.; KANGARA, N.; GARDENER, C.; FORNER-MARTÍNEZ, M.; LIU, J.; YU, G.; BODEN, S.A.; PASCUCCI, A.; GHOSH, S.; HAFEEZ, A.N.; O'HARA, T.; WAITES, J.; CHEEMA, J.; STEUERNAGEL, B.; PATPOUR, M.; JUSTESEN, A.F.; LIU, S.; RUDD, J. C.; AVNI, R.; SHARON, A.R; STEINER, B.; KIRANA, R.P.; BUERSTMAYR, H.; MEHRABI, A.A.; NASYROVA, F.Y.; CHAYUT, N.; MATNY, O.; STEFFENSON, B. J.; SANDHU, N.; CHHUNEJA, P.; LAGUDAH, E.; ELKOT, A.F.; TYRRELL, S.; BIAN, X.; DAVEY, R.P.; SIMONSEN, M.; SCHAUSER, L.; TIWARI, V.K.; RANDY KUTCHER, H.; HUCL, P.; LI, A.; LIU, D.C.; MAO, L.; XU, S.; BROWN-GUEDIRA, G.; FARIS, J.; DVORAK, J.; LUO, M.CH.; KRASILEVA, K.; LUX, T.; ARTMEIER, S.; MAYER, K. F. X.; UAUY, C.; MASCHER, M.; BENTLEY, A.R.; KELLER, B.; POLAND, J.; WULFF, B. B. H. |
Afiliación : |
KUMAR GAURAV; SANU ARORA; MARIA PAULA SILVA VILLELLA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement. |
Fecha de publicación : |
2022 |
Fuente / Imprenta : |
Nature Biotechnology, Volume 40, Pages 422-431, March 2022. Open Access. doi: https://doi.org/10.1038/s41587-021-01058-4 |
DOI : |
10.1038/s41587-021-01058-4 |
Idioma : |
Inglés |
Contenido : |
Abstract:
Aegilops tauschii, the diploid wild progenitor of the D subgenome of bread wheat, is a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Here we sequenced 242 Ae. tauschii accessions and compared them to the wheat D subgenome to characterize genomic diversity. We found that a rare lineage of Ae. tauschii geographically restricted to present-day Georgia contributed to the wheat D subgenome in the independent hybridizations that gave rise to modern bread wheat. Through k-mer-based association mapping, we identified discrete genomic regions with candidate genes for disease and pest resistance and demonstrated their functional transfer into wheat by transgenesis and wide crossing, including the generation of a library of hexaploids incorporating diverse Ae. tauschii genomes. Exploiting the genomic diversity of the Ae. tauschii ancestral diploid genome permits rapid trait discovery and functional genetic validation in a hexaploid background amenable to breeding.
Autores: Kumar Gaurav, Sanu Arora, Paula Silva, Javier Sánchez-Martín, Richard Horsnell, Liangliang Gao, Gurcharn S. Brar, Victoria Widrig, W. John Raupp, Narinder Singh, Shuangye Wu, Sandip M. Kale, Catherine Chinoy, Paul Nicholson, Jesús Quiroz-Chávez, James Simmonds, Sadiye Hayta, Mark A. Smedley, Wendy Harwood, Suzannah Pearce, David Gilbert, Ngonidzashe Kangara, Catherine Gardener, Macarena Forner-Martínez, Jiaqian Liu, Guotai Yu, Scott A. Boden, Attilio Pascucci, Sreya Ghosh, Amber N. Hafeez, Tom O?Hara, Joshua Waites, Jitender Cheema, Burkhard Steuernagel, Mehran Patpour, Annemarie Fejer Justesen, Shuyu Liu, Jackie C. Rudd, Raz Avni, Amir Sharon, Barbara Steiner, Rizky Pasthika Kirana, Hermann Buerstmayr, Ali A. Mehrabi, Firuza Y. Nasyrova, Noam Chayut, Oadi Matny, Brian J. Steffenson, Nitika Sandhu, Parveen Chhuneja, Evans Lagudah, Ahmed F. Elkot, Simon Tyrrell, Xingdong Bian, Robert P. Davey, Martin Simonsen, Leif Schauser, Vijay K. Tiwari, H. Randy Kutcher, Pierre Hucl, Aili Li, Deng-Cai Liu, Long Mao, Steven Xu, Gina Brown-Guedira, Justin Faris, Jan Dvorak, Ming-Cheng Luo, Ksenia Krasileva, Thomas Lux, Susanne Artmeier, Klaus F. X. Mayer, Cristobal Uauy, Martin Mascher, Alison R. Bentley, Beat Keller, Jesse Poland & Brande B. H. Wulff MenosAbstract:
Aegilops tauschii, the diploid wild progenitor of the D subgenome of bread wheat, is a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Here we sequenced 242 Ae. tauschii accessions and compared them to the wheat D subgenome to characterize genomic diversity. We found that a rare lineage of Ae. tauschii geographically restricted to present-day Georgia contributed to the wheat D subgenome in the independent hybridizations that gave rise to modern bread wheat. Through k-mer-based association mapping, we identified discrete genomic regions with candidate genes for disease and pest resistance and demonstrated their functional transfer into wheat by transgenesis and wide crossing, including the generation of a library of hexaploids incorporating diverse Ae. tauschii genomes. Exploiting the genomic diversity of the Ae. tauschii ancestral diploid genome permits rapid trait discovery and functional genetic validation in a hexaploid background amenable to breeding.
Autores: Kumar Gaurav, Sanu Arora, Paula Silva, Javier Sánchez-Martín, Richard Horsnell, Liangliang Gao, Gurcharn S. Brar, Victoria Widrig, W. John Raupp, Narinder Singh, Shuangye Wu, Sandip M. Kale, Catherine Chinoy, Paul Nicholson, Jesús Quiroz-Chávez, James Simmonds, Sadiye Hayta, Mark A. Smedley, Wendy Harwood, Suzannah Pearce, David Gilbert, Ngonidzashe Kangara, Catherine Gardener, Macarena Forner-Martínez, Jiaqian Liu, Guotai Yu, Scott A. Boden, Attilio Pas... Presentar Todo |
Palabras claves : |
Hexaploid bread; WHEAT. |
Thesagro : |
MEJORAMIENTO GENETICO; TRITICUM AESTIVUM. |
Asunto categoría : |
-- |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16672/1/s41587-021-01058-4-1.pdf
https://www.nature.com/articles/s41587-021-01058-4.pdf
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Marc : |
LEADER 04120naa a2200325 a 4500 001 1062533 005 2022-09-02 008 2022 bl uuuu u00u1 u #d 024 7 $a10.1038/s41587-021-01058-4$2DOI 100 1 $aGAURAV, K. 245 $aPopulation genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement.$h[electronic resource] 260 $c2022 520 $aAbstract: Aegilops tauschii, the diploid wild progenitor of the D subgenome of bread wheat, is a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Here we sequenced 242 Ae. tauschii accessions and compared them to the wheat D subgenome to characterize genomic diversity. We found that a rare lineage of Ae. tauschii geographically restricted to present-day Georgia contributed to the wheat D subgenome in the independent hybridizations that gave rise to modern bread wheat. Through k-mer-based association mapping, we identified discrete genomic regions with candidate genes for disease and pest resistance and demonstrated their functional transfer into wheat by transgenesis and wide crossing, including the generation of a library of hexaploids incorporating diverse Ae. tauschii genomes. Exploiting the genomic diversity of the Ae. tauschii ancestral diploid genome permits rapid trait discovery and functional genetic validation in a hexaploid background amenable to breeding. Autores: Kumar Gaurav, Sanu Arora, Paula Silva, Javier Sánchez-Martín, Richard Horsnell, Liangliang Gao, Gurcharn S. Brar, Victoria Widrig, W. John Raupp, Narinder Singh, Shuangye Wu, Sandip M. Kale, Catherine Chinoy, Paul Nicholson, Jesús Quiroz-Chávez, James Simmonds, Sadiye Hayta, Mark A. Smedley, Wendy Harwood, Suzannah Pearce, David Gilbert, Ngonidzashe Kangara, Catherine Gardener, Macarena Forner-Martínez, Jiaqian Liu, Guotai Yu, Scott A. Boden, Attilio Pascucci, Sreya Ghosh, Amber N. Hafeez, Tom O?Hara, Joshua Waites, Jitender Cheema, Burkhard Steuernagel, Mehran Patpour, Annemarie Fejer Justesen, Shuyu Liu, Jackie C. Rudd, Raz Avni, Amir Sharon, Barbara Steiner, Rizky Pasthika Kirana, Hermann Buerstmayr, Ali A. Mehrabi, Firuza Y. Nasyrova, Noam Chayut, Oadi Matny, Brian J. Steffenson, Nitika Sandhu, Parveen Chhuneja, Evans Lagudah, Ahmed F. Elkot, Simon Tyrrell, Xingdong Bian, Robert P. Davey, Martin Simonsen, Leif Schauser, Vijay K. Tiwari, H. Randy Kutcher, Pierre Hucl, Aili Li, Deng-Cai Liu, Long Mao, Steven Xu, Gina Brown-Guedira, Justin Faris, Jan Dvorak, Ming-Cheng Luo, Ksenia Krasileva, Thomas Lux, Susanne Artmeier, Klaus F. X. Mayer, Cristobal Uauy, Martin Mascher, Alison R. Bentley, Beat Keller, Jesse Poland & Brande B. H. Wulff 650 $aMEJORAMIENTO GENETICO 650 $aTRITICUM AESTIVUM 653 $aHexaploid bread 653 $aWHEAT 700 1 $aARORA, S. 700 1 $aSILVA, P. 700 1 $aSÁNCHEZ-MARTÍN, J. 700 1 $aHORSNELL,R. 700 1 $aGAO, L. 700 1 $aBRAR ,G.S. 700 1 $aWIDRIG,V. 700 1 $aJOHN RAUPP,W. 700 1 $aSINGH, N. 700 1 $aWU, S. 700 1 $aKALE, S.M. 700 1 $aCHINOY, C.; NICHOLSON, P.; QUIROZ-CHÁVEZ, J.; SIMMONDS, J.; HAYTA, S.; SMEDLEY, M. A; HARWOOD, W.; PEARCE, S.; GILBERT, D.; KANGARA, N.; GARDENER, C.; FORNER-MARTÍNEZ, M.; LIU, J.; YU, G.; BODEN, S.A.; PASCUCCI, A.; GHOSH, S.; HAFEEZ, A.N.; O'HARA, T.; WAITES, J.; CHEEMA, J.; STEUERNAGEL, B.; PATPOUR, M.; JUSTESEN, A.F.; LIU, S.; RUDD, J. C.; AVNI, R.; SHARON, A.R; STEINER, B.; KIRANA, R.P.; BUERSTMAYR, H.; MEHRABI, A.A.; NASYROVA, F.Y.; CHAYUT, N.; MATNY, O.; STEFFENSON, B. J.; SANDHU, N.; CHHUNEJA, P.; LAGUDAH, E.; ELKOT, A.F.; TYRRELL, S.; BIAN, X.; DAVEY, R.P.; SIMONSEN, M.; SCHAUSER, L.; TIWARI, V.K.; RANDY KUTCHER, H.; HUCL, P.; LI, A.; LIU, D.C.; MAO, L.; XU, S.; BROWN-GUEDIRA, G.; FARIS, J.; DVORAK, J.; LUO, M.CH.; KRASILEVA, K.; LUX, T.; ARTMEIER, S.; MAYER, K. F. X.; UAUY, C.; MASCHER, M.; BENTLEY, A.R.; KELLER, B.; POLAND, J.; WULFF, B. B. H. 773 $tNature Biotechnology, Volume 40, Pages 422-431, March 2022. Open Access. doi: https://doi.org/10.1038/s41587-021-01058-4
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Registro original : |
INIA La Estanzuela (LE) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
18/04/2023 |
Actualizado : |
18/04/2023 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
CASAUX, M.L.; D'ALESSANDRO, B.; VIGNOLI, R.; FRAGA, M. |
Afiliación : |
MARÍA LAURA CASAUX, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; BRUNO D'ALESSANDRO, Departamento de Desarrollo Biotecnológico, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay; RAFAEL VIGNOLI, Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay; MARTIN FRAGA COTELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Phenotypic and genotypic survey of antibiotic resistance in Salmonella enterica isolates from dairy farms in Uruguay. |
Fecha de publicación : |
2023 |
Fuente / Imprenta : |
Frontiers in Veterinary Science, 2023, Volume 10, article 1055432. OPEN ACCESS. doi: https://doi.org/10.3389/fvets.2023.1055432 |
ISSN : |
2297-1769 |
DOI : |
10.3389/fvets.2023.1055432 |
Idioma : |
Inglés |
Notas : |
Article history: Received 27 September 2022; Accepted 15 February 2023; Published 09 March 2023. -- Correspondence author: María Laura Casaux, lcasaux@inia.org.uy; Martín Fraga, mfraga@inia.org.uy -- Edited by: Julio Alvarez, VISAVET Health Surveillance Centre (UCM), Spain. -- Reviewed by:
Abraham Loera Muro, Centro de Investigación Biológica del Noroeste (CIBNOR), Mexico; Ruixi Chen, Massachusetts Institute of Technology, United States; Takele Beyene Tufa, Addis Ababa University, Ethiopia -- This article is part of the Research Topic Antimicrobial Resistance in Zoonotic Bacteria in Developing Countries: The Role of Food Animal Production in Public Health, Volume II (https://www.frontiersin.org/research-topics/34607#articles ) -- License: This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). (http://creativecommons.org/licenses/by/4.0/ ) |
Contenido : |
Salmonella enterica is an important zoonotic pathogen that is frequently identified in dairy farming systems. An increase in antibiotic resistance has led to inadequate results of treatments, with impacts on animal and human health. Here, the phenotypic and genotypic susceptibility patterns of Salmonella isolates from dairy cattle and dairy farm environments were evaluated and compared. A collection of 75 S. enterica isolates were evaluated, and their phenotypic susceptibility was determined. For genotypic characterization, the whole genomes of the isolates were sequenced, and geno-serotypes, sequence types (STs) and core-genome-sequence types were determined using the EnteroBase pipeline. Copyright © 2023 Casaux, D'Alessandro, Vignoli and Fraga. |
Palabras claves : |
Antimicrobial resistance; Bovine salmonellosis; Calves; Genotyping; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL; WGS. |
Asunto categoría : |
L01 Ganadería |
URL : |
https://www.frontiersin.org/articles/10.3389/fvets.2023.1055432/pdf
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Marc : |
LEADER 02548naa a2200265 a 4500 001 1064039 005 2023-04-18 008 2023 bl uuuu u00u1 u #d 022 $a2297-1769 024 7 $a10.3389/fvets.2023.1055432$2DOI 100 1 $aCASAUX, M.L. 245 $aPhenotypic and genotypic survey of antibiotic resistance in Salmonella enterica isolates from dairy farms in Uruguay.$h[electronic resource] 260 $c2023 500 $aArticle history: Received 27 September 2022; Accepted 15 February 2023; Published 09 March 2023. -- Correspondence author: María Laura Casaux, lcasaux@inia.org.uy; Martín Fraga, mfraga@inia.org.uy -- Edited by: Julio Alvarez, VISAVET Health Surveillance Centre (UCM), Spain. -- Reviewed by: Abraham Loera Muro, Centro de Investigación Biológica del Noroeste (CIBNOR), Mexico; Ruixi Chen, Massachusetts Institute of Technology, United States; Takele Beyene Tufa, Addis Ababa University, Ethiopia -- This article is part of the Research Topic Antimicrobial Resistance in Zoonotic Bacteria in Developing Countries: The Role of Food Animal Production in Public Health, Volume II (https://www.frontiersin.org/research-topics/34607#articles ) -- License: This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). (http://creativecommons.org/licenses/by/4.0/ ) 520 $aSalmonella enterica is an important zoonotic pathogen that is frequently identified in dairy farming systems. An increase in antibiotic resistance has led to inadequate results of treatments, with impacts on animal and human health. Here, the phenotypic and genotypic susceptibility patterns of Salmonella isolates from dairy cattle and dairy farm environments were evaluated and compared. A collection of 75 S. enterica isolates were evaluated, and their phenotypic susceptibility was determined. For genotypic characterization, the whole genomes of the isolates were sequenced, and geno-serotypes, sequence types (STs) and core-genome-sequence types were determined using the EnteroBase pipeline. Copyright © 2023 Casaux, D'Alessandro, Vignoli and Fraga. 653 $aAntimicrobial resistance 653 $aBovine salmonellosis 653 $aCalves 653 $aGenotyping 653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL 653 $aWGS 700 1 $aD'ALESSANDRO, B. 700 1 $aVIGNOLI, R. 700 1 $aFRAGA, M. 773 $tFrontiers in Veterinary Science, 2023, Volume 10, article 1055432. OPEN ACCESS. doi: https://doi.org/10.3389/fvets.2023.1055432
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