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Biblioteca (s) : |
INIA Tacuarembó. |
Fecha : |
15/12/2017 |
Actualizado : |
27/03/2019 |
Tipo de producción científica : |
Poster |
Autor : |
WALLACE, F.; BENNADJI, Z.; FERREIRA, F.; OLIVARO, C. |
Afiliación : |
FEDERICO WALLACE; ZOHRA BENNADJI SOUALHIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO AMAURY FERREIRA CHIESA; CRISTINA OLIVARO. |
Título : |
Analysis of an immunoadjuvant saponin fraction from Quillaja brasiliensis leaves by Electrospray Ionization Ion Trap Multiple-Stage Mass Spectrometry. [Resumen de poster]. |
Fecha de publicación : |
2017 |
Fuente / Imprenta : |
In: Escola de Espectrometria de Massas, 3., BrMASS, Natal-RN , 03 a 08 de dezembro, 2017. |
Idioma : |
Español |
Contenido : |
Saponins are natural surfactant compounds whose aqueous solutions can form stable foam and micellar solutions. They are glycosides formed by one, two or three oligosaccharide chains linked to a steroid or triterpene aglycone through acetal and/or ester-acetal bonds. Quillaja brasiliensis is an endemic tree species in southern
Brazil and northern Uruguay. It has been shown in experimental vaccines in animal models that the aqueous extract and some of the purified saponin fractions obtained from leaves of Q. brasiliensis have immunoadjuvant activity comparable with Quil-A®, the main commercial adjuvant product based on Q. saponaria saponins [1, 2]. These saponins are also able to form ISCOM- type nanometric micellar structures which are even more effective vaccine adjuvants, generating both humoral and
cellular immune responses [2]. The aim of this study was to perform a preliminary structural characterization of the immunoadjuvant fraction of saponins designated as Fraction B. |
Palabras claves : |
QUILLAJA BRASILIENSIS. |
Thesagro : |
SAPONINAS. |
Asunto categoría : |
K10 Producción forestal |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/8137/1/Resumen-Poster-2017-Bennadji.pdf
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Marc : |
LEADER 01624nam a2200169 a 4500 001 1057892 005 2019-03-27 008 2017 bl uuuu u00u1 u #d 100 1 $aWALLACE, F. 245 $aAnalysis of an immunoadjuvant saponin fraction from Quillaja brasiliensis leaves by Electrospray Ionization Ion Trap Multiple-Stage Mass Spectrometry. [Resumen de poster].$h[electronic resource] 260 $aIn: Escola de Espectrometria de Massas, 3., BrMASS, Natal-RN , 03 a 08 de dezembro$c2017 520 $aSaponins are natural surfactant compounds whose aqueous solutions can form stable foam and micellar solutions. They are glycosides formed by one, two or three oligosaccharide chains linked to a steroid or triterpene aglycone through acetal and/or ester-acetal bonds. Quillaja brasiliensis is an endemic tree species in southern Brazil and northern Uruguay. It has been shown in experimental vaccines in animal models that the aqueous extract and some of the purified saponin fractions obtained from leaves of Q. brasiliensis have immunoadjuvant activity comparable with Quil-A®, the main commercial adjuvant product based on Q. saponaria saponins [1, 2]. These saponins are also able to form ISCOM- type nanometric micellar structures which are even more effective vaccine adjuvants, generating both humoral and cellular immune responses [2]. The aim of this study was to perform a preliminary structural characterization of the immunoadjuvant fraction of saponins designated as Fraction B. 650 $aSAPONINAS 653 $aQUILLAJA BRASILIENSIS 700 1 $aBENNADJI, Z. 700 1 $aFERREIRA, F. 700 1 $aOLIVARO, C.
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INIA Tacuarembó (TBO) |
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
16/04/2024 |
Actualizado : |
16/04/2024 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
SOUSA, A.L.V.; SOUSA, D.E.R.; CERQUEIRA, L.A.; QUEIROZ-MACHADO, C.R.R.; GIARETTA, P.R.; RIET-CORREA, F.; CASTRO, M.B.; MACHADO, M. |
Afiliación : |
ANA LÍVIA V. SOUSA, Laboratório de Patologia Veterinária (LPV), Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Via L4 Norte, Asa Norte, Brasília, DF, 70636-200, Brazil; DAVI E.R. SOUSA, Laboratório de Patologia Veterinária (LPV), Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Brasília, Brazil; Graduate Program in Animal Science, Faculdade Agronomia e Medicina Veterinária (FAV), Universidade de Brazil; LIZ A. CERQUEIRA, Laboratório de Patologia Veterinária (LPV), Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Brasília, Brazil; Graduate Program in Animal Science, Faculdade Agronomia e Medicina Veterinária (FAV), Universidade de Brazil; CINTIA R.R. QUEIROZ-MACHADO, CENUR Noreste, Universidad de la República (UdelaR), Ruta 5 Km 386, Tacuarembó, 45000, Uruguay; PAULA R. GIARETTA, Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States; FRANKLIN RIET-CORREA AMARAL, Graduate Program in Animal Science in the Tropics (PPGCAT), Faculdade de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia (UFBA), Av. Adhemar de Barros 500, Ondina, BA, Salvador, 40170-110, Brazil; MÁRCIO B. CASTRO, Laboratório de Patologia Veterinária (LPV), Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Brasília, Brazil; Graduate Program in Animal Science, Faculdade Agronomia e Medicina Veterinária (FAV), Universidade de Brazil; MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Graduate Program in Animal Science, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Campus Darcy Ribeiro, Brasília, DF, Brazil. |
Título : |
Cestrum axillare hepatotoxicity in cattle in the Distrito Federal, Goiás and Minas Gerais. [Hepatotoxicidade do Cestrum axillare em bovinos do Distrito Federal, Goiás e Minas Gerais].. |
Complemento del título : |
Original Article. Livestock Diseases. |
Fecha de publicación : |
2024 |
Fuente / Imprenta : |
Pesquisa Veterinaria Brasileira. 2024, Volume 44, e07399. https://doi.org/10.1590/1678-5150-PVB-7399 -- OPEN ACCESS. |
ISSN : |
0100-736X |
DOI : |
10.1590/1678-5150-PVB-7399 |
Idioma : |
Inglés |
Notas : |
Article history: Received 08 Nov 2023, Accepted 09 Dec 2023, Publication in this collection 18 Mar 2024, Date of issue 2024. -- Correspondence: Machado, M.; Graduate Program in Animal Science, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Campus Darcy Ribeiro, ICC Norte, Asa Norte, Brasília, DF, Brazil; email:mmachado@inia.org.uy -- Document type: Article Gold Open Access. -- LICENSE: This is an open-access article distributed under the terms of the Creative Commons Attribution License https://creativecommons.org/licenses/by/4.0/ |
Contenido : |
ABSTRACT.- This study reports four outbreaks of Cestrum axillare poisoning in cattle. Outbreaks occurred in farms of the Distrito Federal, Goiás, and Minas Gerais states during the dry season, affecting cows and heifers, with a mortality rate of 1 to 14,28%. Poisoned animals showed neurological signs and recumbency, followed by death within 12 hours, and some animals were found dead. Gross and histological lesions were typical of acute hepatotoxicity with hepatomegaly, enhancement of lobular pattern, and centrilobular to massive necrosis. This study seems to be the first report on C. axillare poisoning in cattle in the Distrito Federal, Goiás, and Triângulo Mineiro. C. axillare poisoning must be included in the differential diagnosis for cattle with hepatic necrosis in these locations. .-.-.-.-.-.-.-.-.-. RESUMO.- Este estudo relata quatro surtos de intoxicação por Cestrum axillare em bovinos. Os surtos ocorreram em fazendas do Distrito Federal, Goiás e Minas Gerais durante a estação seca, afetando vacas e novilhas, com taxa de mortalidade de 1 a 14,28%. Os animais afetados apresentaram sinais neurológicos e decúbito, seguidos de óbito em 12 horas. Alguns animais foram encontrados mortos. Foram observadas lesões macroscópicas e histológicas típicas de hepatotoxicidade aguda como hepatomegalia, evidenciação do padrão lobular e necrose centrolobular a massiva. Este é o primeiro relato de intoxicação por C. axillare em bovinos no Distrito Federal, Goiás e Triângulo Mineiro. A intoxicação por Cestrum axillare deve ser incluída no diagnóstico diferencial de bovinos com necrose hepática nessas localidades. © 2024 Colegio Brasileiro de Patologia Animal. All rights reserved. MenosABSTRACT.- This study reports four outbreaks of Cestrum axillare poisoning in cattle. Outbreaks occurred in farms of the Distrito Federal, Goiás, and Minas Gerais states during the dry season, affecting cows and heifers, with a mortality rate of 1 to 14,28%. Poisoned animals showed neurological signs and recumbency, followed by death within 12 hours, and some animals were found dead. Gross and histological lesions were typical of acute hepatotoxicity with hepatomegaly, enhancement of lobular pattern, and centrilobular to massive necrosis. This study seems to be the first report on C. axillare poisoning in cattle in the Distrito Federal, Goiás, and Triângulo Mineiro. C. axillare poisoning must be included in the differential diagnosis for cattle with hepatic necrosis in these locations. .-.-.-.-.-.-.-.-.-. RESUMO.- Este estudo relata quatro surtos de intoxicação por Cestrum axillare em bovinos. Os surtos ocorreram em fazendas do Distrito Federal, Goiás e Minas Gerais durante a estação seca, afetando vacas e novilhas, com taxa de mortalidade de 1 a 14,28%. Os animais afetados apresentaram sinais neurológicos e decúbito, seguidos de óbito em 12 horas. Alguns animais foram encontrados mortos. Foram observadas lesões macroscópicas e histológicas típicas de hepatotoxicidade aguda como hepatomegalia, evidenciação do padrão lobular e necrose centrolobular a massiva. Este é o primeiro relato de intoxicação por C. axillare em bovinos no Distrito Federal, Goiás e Triângulo Mineiro. A i... Presentar Todo |
Palabras claves : |
Bovinos; Cattle; Cestrum axillare; Hepatotoxicidade aguda; Hepatotoxicosis; Plantas tóxicas; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA; Poisonous plants. |
Asunto categoría : |
L73 Enfermedades de los animales |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/17605/1/10.15901678-5150-PVB-7399.pdf
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Marc : |
LEADER 03452naa a2200337 a 4500 001 1064592 005 2024-04-16 008 2024 bl uuuu u00u1 u #d 022 $a0100-736X 024 7 $a10.1590/1678-5150-PVB-7399$2DOI 100 1 $aSOUSA, A.L.V. 245 $aCestrum axillare hepatotoxicity in cattle in the Distrito Federal, Goiás and Minas Gerais. [Hepatotoxicidade do Cestrum axillare em bovinos do Distrito Federal, Goiás e Minas Gerais]..$h[electronic resource] 260 $c2024 500 $aArticle history: Received 08 Nov 2023, Accepted 09 Dec 2023, Publication in this collection 18 Mar 2024, Date of issue 2024. -- Correspondence: Machado, M.; Graduate Program in Animal Science, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Campus Darcy Ribeiro, ICC Norte, Asa Norte, Brasília, DF, Brazil; email:mmachado@inia.org.uy -- Document type: Article Gold Open Access. -- LICENSE: This is an open-access article distributed under the terms of the Creative Commons Attribution License https://creativecommons.org/licenses/by/4.0/ 520 $aABSTRACT.- This study reports four outbreaks of Cestrum axillare poisoning in cattle. Outbreaks occurred in farms of the Distrito Federal, Goiás, and Minas Gerais states during the dry season, affecting cows and heifers, with a mortality rate of 1 to 14,28%. Poisoned animals showed neurological signs and recumbency, followed by death within 12 hours, and some animals were found dead. Gross and histological lesions were typical of acute hepatotoxicity with hepatomegaly, enhancement of lobular pattern, and centrilobular to massive necrosis. This study seems to be the first report on C. axillare poisoning in cattle in the Distrito Federal, Goiás, and Triângulo Mineiro. C. axillare poisoning must be included in the differential diagnosis for cattle with hepatic necrosis in these locations. .-.-.-.-.-.-.-.-.-. RESUMO.- Este estudo relata quatro surtos de intoxicação por Cestrum axillare em bovinos. Os surtos ocorreram em fazendas do Distrito Federal, Goiás e Minas Gerais durante a estação seca, afetando vacas e novilhas, com taxa de mortalidade de 1 a 14,28%. Os animais afetados apresentaram sinais neurológicos e decúbito, seguidos de óbito em 12 horas. Alguns animais foram encontrados mortos. Foram observadas lesões macroscópicas e histológicas típicas de hepatotoxicidade aguda como hepatomegalia, evidenciação do padrão lobular e necrose centrolobular a massiva. Este é o primeiro relato de intoxicação por C. axillare em bovinos no Distrito Federal, Goiás e Triângulo Mineiro. A intoxicação por Cestrum axillare deve ser incluída no diagnóstico diferencial de bovinos com necrose hepática nessas localidades. © 2024 Colegio Brasileiro de Patologia Animal. All rights reserved. 653 $aBovinos 653 $aCattle 653 $aCestrum axillare 653 $aHepatotoxicidade aguda 653 $aHepatotoxicosis 653 $aPlantas tóxicas 653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA 653 $aPoisonous plants 700 1 $aSOUSA, D.E.R. 700 1 $aCERQUEIRA, L.A. 700 1 $aQUEIROZ-MACHADO, C.R.R. 700 1 $aGIARETTA, P.R. 700 1 $aRIET-CORREA, F. 700 1 $aCASTRO, M.B. 700 1 $aMACHADO, M. 773 $tPesquisa Veterinaria Brasileira. 2024, Volume 44, e07399. https://doi.org/10.1590/1678-5150-PVB-7399 -- OPEN ACCESS.
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