|
|
Registro completo
|
Biblioteca (s) : |
INIA Las Brujas; INIA Treinta y Tres. |
Fecha : |
21/02/2014 |
Actualizado : |
16/05/2022 |
Autor : |
JACKSON, M.L. |
Título : |
Análisis químico de suelos |
Fecha de publicación : |
1964 |
Fuente / Imprenta : |
Barcelona (España): Omega, 1964. |
Páginas : |
662p. |
Idioma : |
Español |
Thesagro : |
ANALISIS DEL SUELO; ESPECTROMETRIA; ESTRUCTURA DEL SUELO; EXPERIMENTACION; FOSFORO; MANEJO DEL SUELO; MATERIA ORGANICA DEL SUELO; MUESTREO; NITROGENO; PH DEL SUELO; POTASIO; PROPIEDADES FISICO-QUIMICAS SUELO; QUIMICA DEL SUELO; SALINIDAD; SUELO. |
Asunto categoría : |
-- |
Marc : |
LEADER 00739nam a2200289 a 4500 001 1000080 005 2022-05-16 008 1964 bl uuuu u00u1 u #d 100 1 $aJACKSON, M.L. 245 $aAnálisis químico de suelos 260 $aBarcelona (España): Omega$c1964 300 $a662p. 650 $aANALISIS DEL SUELO 650 $aESPECTROMETRIA 650 $aESTRUCTURA DEL SUELO 650 $aEXPERIMENTACION 650 $aFOSFORO 650 $aMANEJO DEL SUELO 650 $aMATERIA ORGANICA DEL SUELO 650 $aMUESTREO 650 $aNITROGENO 650 $aPH DEL SUELO 650 $aPOTASIO 650 $aPROPIEDADES FISICO-QUIMICAS SUELO 650 $aQUIMICA DEL SUELO 650 $aSALINIDAD 650 $aSUELO
Descargar
Esconder MarcPresentar Marc Completo |
Registro original : |
INIA Las Brujas (LB) |
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
|
Registro completo
|
Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
05/02/2020 |
Actualizado : |
05/02/2020 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
SIGDEL, A.; ABDOLLAHI-ARPANAHI, R.; AGUILAR, I.; PEÑAGARICANO, F. |
Afiliación : |
ANIL SIGDEL, Department of Animal Sciences, University of Florida, Gainesville, FL, United States; ROSTAM ABDOLLAHI-ARPANAHI, Department of Animal Sciences, University of Florida, Gainesville, FL, United States; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FRANCISCO PEÑAGARICANO, Department of Animal Sciences, University of Florida, Gainesville, FL, United States; University of Florida Genetics Institute, University of Florida, Gainesville, FL, United States. |
Título : |
Whole genome mapping reveals novel genes and pathways involved in milk production under heat stress in US Holstein cows. |
Fecha de publicación : |
2019 |
Fuente / Imprenta : |
Frontiers in Genetics, 4 October 2019, Volume 10, Article number 928. OPEN ACCESS. Doi: https://doi.org/10.3389/fgene.2019.00928 |
ISSN : |
1664-8021 |
DOI : |
10.3389/fgene.2019.00928 |
Idioma : |
Inglés |
Notas : |
Article history: Received: 19 May 2019 / Accepted: 05 September 2019 / Published: 04 October 2019.
Specialty section: This article was submitted to Livestock Genomics, a section of the journal Frontiers in Genetics.
Corresponding author: Francisco Peñagaricano - fpenagaricano@ufl.edu |
Contenido : |
ABSTACT.
Heat stress represents a major environmental factor that negatively affects the health and performance of dairy cows, causing huge economic losses to the dairy industry. Identifying and selecting animals that are thermotolerant is an attractive alternative for reducing the negative effects of heat stress on dairy cattle performance. As such, the objectives of the present study were to estimate genetic components of milk yield, fat yield, and protein yield considering heat stress and to perform whole-genome scans and a subsequent gene-set analysis for identifying candidate genes and functional gene-sets implicated in milk production under heat stress conditions. Data consisted of about 254k test-day records from 17,522 Holstein cows. Multi-trait repeatability test day models with random regressions on a function of temperature-humidity index (THI) values were used for genetic analyses. The models included herd-test-day and DIM classes as fixed effects, and general and thermotolerance additive genetic and permanent environmental as random effects. Notably, thermotolerance additive genetic variances for all milk traits increased across parities suggesting that cows become more sensitive to heat stress as they age. In addition, our study revealed negative genetic correlations between general and thermotolerance additive effects, ranging between ?0.18 to ?0.68 indicating that high producing cows are more susceptible to heat stress. The association analysis identified at least three different genomic regions on BTA5, BTA14, and BTA15 strongly associated with milk production under heat stress conditions. These regions harbor candidate genes, such as HSF1, MAPK8IP1, and CDKN1B that are directly involved in the cellular response to heat stress. Moreover, the gene-set analysis revealed several functional terms related to heat shock proteins, apoptosis, immune response, and oxidative stress, among others. Overall, the genes and pathways identified in this study provide a better understanding of the genetic architecture underlying dairy cow performance under heat stress conditions. Our findings point out novel opportunities for improving thermotolerance in dairy cattle through marker-assisted breeding.
© Copyright © 2019 Sigdel, Abdollahi-Arpanahi, Aguilar and Peñagaricano. MenosABSTACT.
Heat stress represents a major environmental factor that negatively affects the health and performance of dairy cows, causing huge economic losses to the dairy industry. Identifying and selecting animals that are thermotolerant is an attractive alternative for reducing the negative effects of heat stress on dairy cattle performance. As such, the objectives of the present study were to estimate genetic components of milk yield, fat yield, and protein yield considering heat stress and to perform whole-genome scans and a subsequent gene-set analysis for identifying candidate genes and functional gene-sets implicated in milk production under heat stress conditions. Data consisted of about 254k test-day records from 17,522 Holstein cows. Multi-trait repeatability test day models with random regressions on a function of temperature-humidity index (THI) values were used for genetic analyses. The models included herd-test-day and DIM classes as fixed effects, and general and thermotolerance additive genetic and permanent environmental as random effects. Notably, thermotolerance additive genetic variances for all milk traits increased across parities suggesting that cows become more sensitive to heat stress as they age. In addition, our study revealed negative genetic correlations between general and thermotolerance additive effects, ranging between ?0.18 to ?0.68 indicating that high producing cows are more susceptible to heat stress. The association analysis identified at ... Presentar Todo |
Palabras claves : |
Gene-set analysis; Genetic parameters; Genomic scan; Heat-shock proteins; Thermotolerance. |
Asunto categoría : |
L10 Genética y mejoramiento animal |
URL : |
https://www.frontiersin.org/articles/10.3389/fgene.2019.00928/pdf
|
Marc : |
LEADER 03448naa a2200253 a 4500 001 1060773 005 2020-02-05 008 2019 bl uuuu u00u1 u #d 022 $a1664-8021 024 7 $a10.3389/fgene.2019.00928$2DOI 100 1 $aSIGDEL, A. 245 $aWhole genome mapping reveals novel genes and pathways involved in milk production under heat stress in US Holstein cows.$h[electronic resource] 260 $c2019 500 $aArticle history: Received: 19 May 2019 / Accepted: 05 September 2019 / Published: 04 October 2019. Specialty section: This article was submitted to Livestock Genomics, a section of the journal Frontiers in Genetics. Corresponding author: Francisco Peñagaricano - fpenagaricano@ufl.edu 520 $aABSTACT. Heat stress represents a major environmental factor that negatively affects the health and performance of dairy cows, causing huge economic losses to the dairy industry. Identifying and selecting animals that are thermotolerant is an attractive alternative for reducing the negative effects of heat stress on dairy cattle performance. As such, the objectives of the present study were to estimate genetic components of milk yield, fat yield, and protein yield considering heat stress and to perform whole-genome scans and a subsequent gene-set analysis for identifying candidate genes and functional gene-sets implicated in milk production under heat stress conditions. Data consisted of about 254k test-day records from 17,522 Holstein cows. Multi-trait repeatability test day models with random regressions on a function of temperature-humidity index (THI) values were used for genetic analyses. The models included herd-test-day and DIM classes as fixed effects, and general and thermotolerance additive genetic and permanent environmental as random effects. Notably, thermotolerance additive genetic variances for all milk traits increased across parities suggesting that cows become more sensitive to heat stress as they age. In addition, our study revealed negative genetic correlations between general and thermotolerance additive effects, ranging between ?0.18 to ?0.68 indicating that high producing cows are more susceptible to heat stress. The association analysis identified at least three different genomic regions on BTA5, BTA14, and BTA15 strongly associated with milk production under heat stress conditions. These regions harbor candidate genes, such as HSF1, MAPK8IP1, and CDKN1B that are directly involved in the cellular response to heat stress. Moreover, the gene-set analysis revealed several functional terms related to heat shock proteins, apoptosis, immune response, and oxidative stress, among others. Overall, the genes and pathways identified in this study provide a better understanding of the genetic architecture underlying dairy cow performance under heat stress conditions. Our findings point out novel opportunities for improving thermotolerance in dairy cattle through marker-assisted breeding. © Copyright © 2019 Sigdel, Abdollahi-Arpanahi, Aguilar and Peñagaricano. 653 $aGene-set analysis 653 $aGenetic parameters 653 $aGenomic scan 653 $aHeat-shock proteins 653 $aThermotolerance 700 1 $aABDOLLAHI-ARPANAHI, R. 700 1 $aAGUILAR, I. 700 1 $aPEÑAGARICANO, F. 773 $tFrontiers in Genetics, 4 October 2019, Volume 10, Article number 928. OPEN ACCESS. Doi: https://doi.org/10.3389/fgene.2019.00928
Descargar
Esconder MarcPresentar Marc Completo |
Registro original : |
INIA Las Brujas (LB) |
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
Expresión de búsqueda válido. Check! |
|
|