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Biblioteca (s) : |
INIA Las Brujas; INIA Tacuarembó. |
Fecha : |
19/07/2015 |
Actualizado : |
11/07/2017 |
Tipo de producción científica : |
Revista INIA |
Autor : |
INIA (INSTITUTO NACIONAL DE INVESTIGACIÓN AGROPECUARIA) |
Título : |
Revista INIA Uruguay. (No.41, Junio 2015). |
Fecha de publicación : |
2015 |
Fuente / Imprenta : |
Montevideo (Uruguay): INIA, 2015. |
Páginas : |
60 p. |
Serie : |
(Revista INIA; 41) |
ISSN : |
1510-9011 |
Idioma : |
Español |
Thesagro : |
ARROZ; BIOTECNOLOGIA; BOVINOS DE CARNE; CAMBIO CLIMÁTICO; CIENCIA; CITRUS; CLIMA; CLIMATOLOGIA; COMUNICACIÓN; CONTROL DE ENFERMEDADES; CULTIVOS DE GRANO; CULTIVOS DE SECANO; ENTOMOLOGIA; ESPECIES FORRAJERAS; EUCALYPTUS; EXPLOTACION AGRICOLA FAMILIAR; FITOPATOLOGÍA; FORESTALES; FORRAJES; FRUTALES; FRUTICULTURA; GANADO BOVINO; GRANOS; GRAS; HORTALIZAS; HORTICULTURA; INIA; INNOVACION; INVESTIGACIÓN; LECHERÍA; LEGUMINOSAS FORRAJERAS; MANEJO DEL CULTIVO; MEJORAMIENTO ANIMAL; METEOROLOGIA; MICROBIOLOGÍA; OVINOS; PASTURAS; PRODUCCIÓN ANIMAL; PRODUCCION DE LANA; PRODUCCION DE LECHE; PRODUCCION LECHERA; REVISTA INIA 2015; SEMILLAS; SOJA; SUELOS; SUINOS; SUSTENTABILIDAD AMBIENTAL; TECNOLOGÍA; TRANSFERENCIA DE TECNOLOGIA; VARIEDADES; VITICULTURA. |
Asunto categoría : |
A50 Investigación agraria |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/4856/1/revista-INIA-41.pdf
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Marc : |
LEADER 01905nam a2200745 a 4500 001 1053106 005 2017-07-11 008 2015 bl uuuu u00u1 u #d 022 $a1510-9011 100 1 $aINIA (INSTITUTO NACIONAL DE INVESTIGACIÓN AGROPECUARIA) 245 $aRevista INIA Uruguay. (No.41, Junio 2015). 260 $aMontevideo (Uruguay): INIA$c2015 300 $a60 p. 490 $a(Revista INIA; 41) 650 $aARROZ 650 $aBIOTECNOLOGIA 650 $aBOVINOS DE CARNE 650 $aCAMBIO CLIMÁTICO 650 $aCIENCIA 650 $aCITRUS 650 $aCLIMA 650 $aCLIMATOLOGIA 650 $aCOMUNICACIÓN 650 $aCONTROL DE ENFERMEDADES 650 $aCULTIVOS DE GRANO 650 $aCULTIVOS DE SECANO 650 $aENTOMOLOGIA 650 $aESPECIES FORRAJERAS 650 $aEUCALYPTUS 650 $aEXPLOTACION AGRICOLA FAMILIAR 650 $aFITOPATOLOGÍA 650 $aFORESTALES 650 $aFORRAJES 650 $aFRUTALES 650 $aFRUTICULTURA 650 $aGANADO BOVINO 650 $aGRANOS 650 $aGRAS 650 $aHORTALIZAS 650 $aHORTICULTURA 650 $aINIA 650 $aINNOVACION 650 $aINVESTIGACIÓN 650 $aLECHERÍA 650 $aLEGUMINOSAS FORRAJERAS 650 $aMANEJO DEL CULTIVO 650 $aMEJORAMIENTO ANIMAL 650 $aMETEOROLOGIA 650 $aMICROBIOLOGÍA 650 $aOVINOS 650 $aPASTURAS 650 $aPRODUCCIÓN ANIMAL 650 $aPRODUCCION DE LANA 650 $aPRODUCCION DE LECHE 650 $aPRODUCCION LECHERA 650 $aREVISTA INIA 2015 650 $aSEMILLAS 650 $aSOJA 650 $aSUELOS 650 $aSUINOS 650 $aSUSTENTABILIDAD AMBIENTAL 650 $aTECNOLOGÍA 650 $aTRANSFERENCIA DE TECNOLOGIA 650 $aVARIEDADES 650 $aVITICULTURA
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Registro original : |
INIA Las Brujas (LB) |
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Biblioteca (s) : |
INIA Treinta y Tres. |
Fecha actual : |
18/04/2022 |
Actualizado : |
01/09/2022 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
RAFFAELLI. S.; ABREO, E.; ALTIER, N.; ALBORÉS, S. |
Afiliación : |
SOFÍA RAFFAELLI, Area de Microbiología, Departamento de Biociencias, Facultad de Química, UDELAR, Uruguay. Laboratorio de Farmacognosia y Productos Naturales, Depto de Química Orgánica, Fac. de Química, UDELAR, Uruguay. Posgrado en Química, Fac. Química. UDELAR, Uruguay.; EDUARDO RAUL ABREO GIMENEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; NORA ADRIANA ALTIER MANZINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SILVANA ALBORÉS, Área de Microbiología, Departamento de Biociencias, Facultad de Química, UDELAR, Uruguay. |
Título : |
Bioprospecting the Antibiofilm and antimicrobial activity of soil and insect gut bacteria. |
Fecha de publicación : |
2022 |
Fuente / Imprenta : |
Molecules, 2022, volume 27, issue 6, article 2002. OPEN ACCESS. Doi: https://doi.org/10.3390/molecules27062002 |
DOI : |
10.3390/molecules27062002 |
Idioma : |
Inglés |
Notas : |
Article history: Received: 20 February 2022 // Revised: 10 March 2022 // Accepted: 16 March 2022 // Published: 21 March 2022.
Correspondence: avazquez@fq.edu.uy; salbores@fq.edu.uy |
Contenido : |
Antimicrobial resistance is a growing concern in public health and current research shows an important role for bacterial biofilms in recurrent or chronic infections. New strategies, therefore, are necessary to overcome antimicrobial resistance, through the development of new therapies that could alter or inhibit biofilm formation. In this sense, antibiofilm natural products are very promising. In this work, a bioprospection of antimicrobial and antibiofilm extracts from Uruguayan soil bacteria and insect gut bacteria was carried out. Extracts from extracellular broths were tested for their ability to inhibit planktonic cell growth and biofilm formation. Genomic analysis of Bacillus cereus ILBB55 was carried out. All extracts were able to inhibit the growth of, at least, one microorganism and several extracts showed MICs lower than 500 µg mL?1 against microorganisms of clinical relevance (Staphylococcus aureus, Pseudomonas aeruginosa, and Enterobacter cloacae). Among the extracts evaluated for biofilm inhibition only ILBB55, from B. cereus, was able to inhibit, S. aureus (99%) and P. aeruginosa (62%) biofilms. Genomic analysis of this strain showed gene clusters similar to other clusters that code for known antimicrobial compounds. Our study revealed that extracts from soil bacteria and insect gut bacteria, especially from B. cereus ILBB55, could be potential candidates for drug discovery to treat infectious diseases and inhibit S. aureus and P. aeruginosa biofilms. |
Palabras claves : |
ANTIBIOFILM; ANTIMICROBIAL; GENOME; PLATAFORMA DE BIOINSUMOS; SOIL BACTERIA. |
Asunto categoría : |
P34 Biología del suelo |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16647/1/Molecules-2022-Raffaelli.pdf
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Marc : |
LEADER 02416naa a2200241 a 4500 001 1063042 005 2022-09-01 008 2022 bl uuuu u00u1 u #d 024 7 $a10.3390/molecules27062002$2DOI 100 1 $aRAFFAELLI. S. 245 $aBioprospecting the Antibiofilm and antimicrobial activity of soil and insect gut bacteria.$h[electronic resource] 260 $c2022 500 $aArticle history: Received: 20 February 2022 // Revised: 10 March 2022 // Accepted: 16 March 2022 // Published: 21 March 2022. Correspondence: avazquez@fq.edu.uy; salbores@fq.edu.uy 520 $aAntimicrobial resistance is a growing concern in public health and current research shows an important role for bacterial biofilms in recurrent or chronic infections. New strategies, therefore, are necessary to overcome antimicrobial resistance, through the development of new therapies that could alter or inhibit biofilm formation. In this sense, antibiofilm natural products are very promising. In this work, a bioprospection of antimicrobial and antibiofilm extracts from Uruguayan soil bacteria and insect gut bacteria was carried out. Extracts from extracellular broths were tested for their ability to inhibit planktonic cell growth and biofilm formation. Genomic analysis of Bacillus cereus ILBB55 was carried out. All extracts were able to inhibit the growth of, at least, one microorganism and several extracts showed MICs lower than 500 µg mL?1 against microorganisms of clinical relevance (Staphylococcus aureus, Pseudomonas aeruginosa, and Enterobacter cloacae). Among the extracts evaluated for biofilm inhibition only ILBB55, from B. cereus, was able to inhibit, S. aureus (99%) and P. aeruginosa (62%) biofilms. Genomic analysis of this strain showed gene clusters similar to other clusters that code for known antimicrobial compounds. Our study revealed that extracts from soil bacteria and insect gut bacteria, especially from B. cereus ILBB55, could be potential candidates for drug discovery to treat infectious diseases and inhibit S. aureus and P. aeruginosa biofilms. 653 $aANTIBIOFILM 653 $aANTIMICROBIAL 653 $aGENOME 653 $aPLATAFORMA DE BIOINSUMOS 653 $aSOIL BACTERIA 700 1 $aABREO, E. 700 1 $aALTIER, N. 700 1 $aALBORÉS, S. 773 $tMolecules, 2022, volume 27, issue 6, article 2002. OPEN ACCESS. Doi: https://doi.org/10.3390/molecules27062002
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