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Registro completo
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Biblioteca (s) : |
INIA Tacuarembó. |
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Fecha : |
21/02/2014 |
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Actualizado : |
14/06/2016 |
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Autor : |
URUGUAY. MINISTERIO DE GANADERÍA, AGRICULTURA Y PESCA (MGAP). DIRECCIÓN DE ESTADÍSTICAS AGROPECUARIAS (DIEA) |
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Título : |
Anuario estadístico agropecuario 1998. |
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Fecha de publicación : |
1998 |
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Fuente / Imprenta : |
Montevideo (Uruguay): MGAP. DIEA, 1998. |
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Páginas : |
168 p. |
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Idioma : |
Español |
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Contenido : |
Capítulo 1. Información general. Capítulo 2. Producción. Capítulo 3. Precios. Capítulo 4. Comercio exterior. Índice de gráficos. Índice de mapas. |
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Palabras claves : |
INFORMACIÓN MACROECONÓMICA. |
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Thesagro : |
ARROZ; CARNE DE CERDO; CARNE DE POLLO; CERDO; COMERCIO EXTERIOR; CUERO; CULTIVOS DE CEREALES; DATOS ESTADISTICOS; FORESTACION; FRUTALES; GANADO DE CARNE; HORTICULTURA; IMPORTACIONES; INDICADORES ECONOMICOS; MANEJO DE PRADERAS; OVINOS; PAPA; PESCA; PRECIOS; PRODUCCION ANIMAL; PRODUCCION DE CARNE; PRODUCCION DE HUEVOS; PRODUCCION DE LANA; PRODUCCION LECHERA; URUGUAY. |
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Asunto categoría : |
-- |
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Marc : |
LEADER 01343nam a2200433 a 4500
001 1017604
005 2016-06-14
008 1998 bl uuuu u00u1 u #d
100 1 $aURUGUAY. MINISTERIO DE GANADERÍA, AGRICULTURA Y PESCA (MGAP). DIRECCIÓN DE ESTADÍSTICAS AGROPECUARIAS (DIEA)
245 $aAnuario estadístico agropecuario 1998.
260 $aMontevideo (Uruguay): MGAP. DIEA$c1998
300 $a168 p.
520 $aCapítulo 1. Información general. Capítulo 2. Producción. Capítulo 3. Precios. Capítulo 4. Comercio exterior. Índice de gráficos. Índice de mapas.
650 $aARROZ
650 $aCARNE DE CERDO
650 $aCARNE DE POLLO
650 $aCERDO
650 $aCOMERCIO EXTERIOR
650 $aCUERO
650 $aCULTIVOS DE CEREALES
650 $aDATOS ESTADISTICOS
650 $aFORESTACION
650 $aFRUTALES
650 $aGANADO DE CARNE
650 $aHORTICULTURA
650 $aIMPORTACIONES
650 $aINDICADORES ECONOMICOS
650 $aMANEJO DE PRADERAS
650 $aOVINOS
650 $aPAPA
650 $aPESCA
650 $aPRECIOS
650 $aPRODUCCION ANIMAL
650 $aPRODUCCION DE CARNE
650 $aPRODUCCION DE HUEVOS
650 $aPRODUCCION DE LANA
650 $aPRODUCCION LECHERA
650 $aURUGUAY
653 $aINFORMACIÓN MACROECONÓMICA
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Registro original : |
INIA Tacuarembó (TBO) |
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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
14/06/2022 |
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Actualizado : |
14/06/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
JARA, E.; PEÑAGARICANO, F.; ARMSTRONG, E.; CIAPPESONI, G.; IRIARTE, A.; NAVAJAS, E. |
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Afiliación : |
EUGENIO JARA, Unidad de Genética y Mejora Animal, Departamento de Producción Animal, Facultad de Veterinaria, Universidad de la República, Montevideo 11600, Uruguay; FRANCISCO PEÑAGARICANO, Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706, United State; EILEEN ARMSTRONG, Unidad de Genética y Mejora Animal, Departamento de Producción Animal, Facultad de Veterinaria, Universidad de la República, 11600, Montevideo, Uruguay; CARLOS GABRIEL CIAPPESONI SCARONE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDRÉS IRIARTE, Laboratorio de Biología Computacional, Departamento de Desarrollo Biotecnológico, Instituto de Higiene, Facultad de Medicina, Universidad de la República, 11600, Montevideo, Uruguay; ELLY ANA NAVAJAS VALENTINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Revealing the genetic basis of eyelid pigmentation in Hereford cattle. |
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Fecha de publicación : |
2022 |
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Fuente / Imprenta : |
Journal of Animal Science, 2022, Volume 100, Issue 5. doi: https://doi.org/10.1093/jas/skac110 |
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ISSN : |
1525-3163 |
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DOI : |
10.1093/jas/skac110 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received December 14, 2021; Accepted April 4, 2022; Advance access publication 7 April 2022.
Corresponding author: Eugenio Jara, email: eugeniojara19@gmail.com -- |
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Contenido : |
ABSTRACT - Ocular squamous cell carcinoma and infectious keratoconjunctivitis are common ocular pathologies in Hereford cattle with considerable economic impact. Both pathologies have been associated with low eyelid pigmentation, and thus, genetic selection for higher eyelid pigmentation could reduce their incidence. The objective of the present study was to reveal the genetic basis of eyelid pigmentation in Hereford cattle. The analysis included a single-step genome-wide association study (ssGWAS) and a subsequent gene-set analysis in order to identify individual genes, genetic mechanisms, and biological pathways implicated in this trait. Data consisted of eyelid pigmentation records in 1,165 Hereford bulls and steers, visually assessed in five categories between 0% and 100%. Genotypic data for 774,660 single-nucleotide polymorphism markers were available for 886 animals with pigmentation records. Pedigree information of three generations of ancestors of animals with phenotype was considered in this study, with a total of 4,929 animals. Our analyses revealed that eyelid pigmentation is a moderately heritable trait, with heritability estimates around 0.41. The ssGWAS identified at least eight regions, located on BTA1, BTA3, BTA5, BTA14, BTA16, BTA18, BTA19, and BTA24, associated with eyelid pigmentation. These regions harbor genes that are directly implicated in melanocyte biology and skin pigmentation, such as ADCY8, PLD1, KITLG, and PRKCA. The gene-set analysis revealed several functional terms closely related to melanogenesis, such as positive regulation of melanocyte differentiation and regulation of ERK1 and ERK2 cascade. Overall, our findings provide evidence that eyelid pigmentation is a heritable trait influenced by many loci. Indeed, the ssGWAS detected several candidate genes that are directly implicated in melanocyte biology, including melanogenesis. This study contributes to a better understanding of the genetic and biological basis of eyelid pigmentation and presents novel information that could aid to design breeding strategies for reducing the incidence of ocular pathologies in cattle. Additional research on the genetic link between eyelid pigmentation and ocular pathologies is needed. © The Author(s) 2022. MenosABSTRACT - Ocular squamous cell carcinoma and infectious keratoconjunctivitis are common ocular pathologies in Hereford cattle with considerable economic impact. Both pathologies have been associated with low eyelid pigmentation, and thus, genetic selection for higher eyelid pigmentation could reduce their incidence. The objective of the present study was to reveal the genetic basis of eyelid pigmentation in Hereford cattle. The analysis included a single-step genome-wide association study (ssGWAS) and a subsequent gene-set analysis in order to identify individual genes, genetic mechanisms, and biological pathways implicated in this trait. Data consisted of eyelid pigmentation records in 1,165 Hereford bulls and steers, visually assessed in five categories between 0% and 100%. Genotypic data for 774,660 single-nucleotide polymorphism markers were available for 886 animals with pigmentation records. Pedigree information of three generations of ancestors of animals with phenotype was considered in this study, with a total of 4,929 animals. Our analyses revealed that eyelid pigmentation is a moderately heritable trait, with heritability estimates around 0.41. The ssGWAS identified at least eight regions, located on BTA1, BTA3, BTA5, BTA14, BTA16, BTA18, BTA19, and BTA24, associated with eyelid pigmentation. These regions harbor genes that are directly implicated in melanocyte biology and skin pigmentation, such as ADCY8, PLD1, KITLG, and PRKCA. The gene-set analysis revealed se... Presentar Todo |
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Palabras claves : |
Beef cattle; Melanocyte biology; Ocular pathologies. |
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Asunto categoría : |
L01 Ganadería |
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Marc : |
LEADER 03180naa a2200253 a 4500
001 1063291
005 2022-06-14
008 2022 bl uuuu u00u1 u #d
022 $a1525-3163
024 7 $a10.1093/jas/skac110$2DOI
100 1 $aJARA, E.
245 $aRevealing the genetic basis of eyelid pigmentation in Hereford cattle.$h[electronic resource]
260 $c2022
500 $aArticle history: Received December 14, 2021; Accepted April 4, 2022; Advance access publication 7 April 2022. Corresponding author: Eugenio Jara, email: eugeniojara19@gmail.com --
520 $aABSTRACT - Ocular squamous cell carcinoma and infectious keratoconjunctivitis are common ocular pathologies in Hereford cattle with considerable economic impact. Both pathologies have been associated with low eyelid pigmentation, and thus, genetic selection for higher eyelid pigmentation could reduce their incidence. The objective of the present study was to reveal the genetic basis of eyelid pigmentation in Hereford cattle. The analysis included a single-step genome-wide association study (ssGWAS) and a subsequent gene-set analysis in order to identify individual genes, genetic mechanisms, and biological pathways implicated in this trait. Data consisted of eyelid pigmentation records in 1,165 Hereford bulls and steers, visually assessed in five categories between 0% and 100%. Genotypic data for 774,660 single-nucleotide polymorphism markers were available for 886 animals with pigmentation records. Pedigree information of three generations of ancestors of animals with phenotype was considered in this study, with a total of 4,929 animals. Our analyses revealed that eyelid pigmentation is a moderately heritable trait, with heritability estimates around 0.41. The ssGWAS identified at least eight regions, located on BTA1, BTA3, BTA5, BTA14, BTA16, BTA18, BTA19, and BTA24, associated with eyelid pigmentation. These regions harbor genes that are directly implicated in melanocyte biology and skin pigmentation, such as ADCY8, PLD1, KITLG, and PRKCA. The gene-set analysis revealed several functional terms closely related to melanogenesis, such as positive regulation of melanocyte differentiation and regulation of ERK1 and ERK2 cascade. Overall, our findings provide evidence that eyelid pigmentation is a heritable trait influenced by many loci. Indeed, the ssGWAS detected several candidate genes that are directly implicated in melanocyte biology, including melanogenesis. This study contributes to a better understanding of the genetic and biological basis of eyelid pigmentation and presents novel information that could aid to design breeding strategies for reducing the incidence of ocular pathologies in cattle. Additional research on the genetic link between eyelid pigmentation and ocular pathologies is needed. © The Author(s) 2022.
653 $aBeef cattle
653 $aMelanocyte biology
653 $aOcular pathologies
700 1 $aPEÑAGARICANO, F.
700 1 $aARMSTRONG, E.
700 1 $aCIAPPESONI, G.
700 1 $aIRIARTE, A.
700 1 $aNAVAJAS, E.
773 $tJournal of Animal Science, 2022, Volume 100, Issue 5. doi: https://doi.org/10.1093/jas/skac110
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