| |
|
|
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas. |
|
Fecha : |
31/03/2021 |
|
Actualizado : |
31/03/2021 |
|
Tipo de producción científica : |
Trabajos en Congresos/Conferencias |
|
Autor : |
MISZTAL, I.; WANG, H.; AGUILAR, I.; LEGARRA, A.; TSURUTA, S.; LOURENCO, D.; FRAGOMENI, B. O.; ZHANG, X.; MUIR, W. M.; CHENG, H. H.; OKIMOTO, R.; WING, T.; HAWKEN, R. R.; ZUMBACH, B.; FERNANDO, R. |
|
Afiliación : |
IGNACY MISZTAL, University of Georgia, Athens, GA, USA; H. WANG, Genus PIC, Hendersonville, TN; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDRÉS LEGARRA, INRA, Toulouse, France; S. TSURUTA, University of Georgia, Athens, GA, USA; D.A.L. LOURENCO, University of Georgia, Athens, GA, USA; B. O. FRAGOMENI, University of Georgia, Athens, GA, USA; X. ZHANG, University of Georgia, Athens, GA, USA; W. M. MUIR, Purdue University, West Lafayette, IN, USA; H. H. CHENG, Cobb-Vantress Inc., Siloam Springs, AR, USA; R. OKIMOTO, Cobb-Vantress Inc., Siloam Springs, AR, USA; T. WING, Cobb-Vantress Inc., Siloam Springs, AR, USA; R. R. HAWKEN, Cobb-Vantress Inc., Siloam Springs, AR, USA; B. ZUMBACH, Cobb-Vantress Inc., Siloam Springs, AR, USA; R. FERNANDO, Department of Animal Science, Iowa State University, Ames, IA, USA. |
|
Título : |
GWAS using ssGBLUP. |
|
Complemento del título : |
Volume Species Breeding: Poultry, 325. |
|
Fecha de publicación : |
2014 |
|
Fuente / Imprenta : |
In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.325. |
|
Idioma : |
Inglés |
|
Contenido : |
ABSTRACT.
This study aimed to compare results of genome-wide associations obtained from various methodologies for GWAS when applied to two lines of broiler chicken. Each line contained >250k birds with 3 traits and 5k SNP60k genotypes. Methods included single-step GWAS, single marker model and BayesB. Mannhattan plots were based on variances of 20-SNP segments, as shorter segments produced noisy plots. Only a few segments explained >1 % of the additive variance. One segment explained >20% variance in BayesB but 3% with ssGWAS and <1% with a single marker model. In two lines, no major segment overlapped for any trait. When analyses used slices of generations (1-3,2-4,3-5,1-5), variances for the same segment varied greatly. The plots were more distinct with a new data set that included >16k genotypes, but no segment explained >1% of the variance. Strength of associations strongly depends on methodologies and details of implementations. |
|
Palabras claves : |
GWAS; SNP variance; SsGBLUP. |
|
Asunto categoría : |
L10 Genética y mejoramiento animal |
|
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/15454/1/Misztal-et-al.-2014.WCGALP.pdf
|
|
Marc : |
LEADER 01803nam a2200313 a 4500
001 1061930
005 2021-03-31
008 2014 bl uuuu u01u1 u #d
100 1 $aMISZTAL, I.
245 $aGWAS using ssGBLUP.$h[electronic resource]
260 $aIn: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.325.$c2014
520 $aABSTRACT. This study aimed to compare results of genome-wide associations obtained from various methodologies for GWAS when applied to two lines of broiler chicken. Each line contained >250k birds with 3 traits and 5k SNP60k genotypes. Methods included single-step GWAS, single marker model and BayesB. Mannhattan plots were based on variances of 20-SNP segments, as shorter segments produced noisy plots. Only a few segments explained >1 % of the additive variance. One segment explained >20% variance in BayesB but 3% with ssGWAS and <1% with a single marker model. In two lines, no major segment overlapped for any trait. When analyses used slices of generations (1-3,2-4,3-5,1-5), variances for the same segment varied greatly. The plots were more distinct with a new data set that included >16k genotypes, but no segment explained >1% of the variance. Strength of associations strongly depends on methodologies and details of implementations.
653 $aGWAS
653 $aSNP variance
653 $aSsGBLUP
700 1 $aWANG, H.
700 1 $aAGUILAR, I.
700 1 $aLEGARRA, A.
700 1 $aTSURUTA, S.
700 1 $aLOURENCO, D.
700 1 $aFRAGOMENI, B. O.
700 1 $aZHANG, X.
700 1 $aMUIR, W. M.
700 1 $aCHENG, H. H.
700 1 $aOKIMOTO, R.
700 1 $aWING, T.
700 1 $aHAWKEN, R. R.
700 1 $aZUMBACH, B.
700 1 $aFERNANDO, R.
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
|
|
 | Acceso al texto completo restringido a Biblioteca INIA La Estanzuela. Por información adicional contacte bib_le@inia.org.uy. |
|
Registro completo
|
|
Biblioteca (s) : |
INIA La Estanzuela. |
|
Fecha actual : |
16/03/2022 |
|
Actualizado : |
16/03/2022 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Circulación / Nivel : |
Internacional - -- |
|
Autor : |
REGUEIRO, M.; JORGE-SMEDING, E.; SARAVIA, A.; LÓPEZ-MAZZ, C.; BANCHERO, G. |
|
Afiliación : |
MARIEL REGUEIRO, Department of Animal Production and Pastures, Faculty of Agronomy, UDELAR, Av. Garzon 780, Montevideo 12900, Uruguay.; EZEQUIEL JORGE-SMEDING, Department of Animal Production and Pastures, Faculty of Agronomy, UDELAR, Av. Garzón 780, Montevideo 12900, Uruguay; ANDERSON SARAVIA DE MELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CARLOS LÓPEZ-MAZZ, Department of Animal Production and Pastures, Faculty of Agronomy, UDELAR, Av. Garzon 780, Montevideo 12900, Uruguay.; GEORGGET ELIZABETH BANCHERO HUNZIKER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
|
Título : |
Comparison between pulse oximetry and venous blood gas analyses to assess lamb asphyxia at parturition. |
|
Fecha de publicación : |
2022 |
|
Fuente / Imprenta : |
Small Ruminant Research, 2022, Volume 21, Article number 106665. doi: https://doi.org/10.1016/j.smallrumres.2022.106665 |
|
DOI : |
10.1016/j.smallrumres.2022.106665 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received 28 June 2021; Received in revised form 2 March 2022; Accepted 3 March 2022; Available online 4 March 2022. |
|
Contenido : |
ABSTRACT: Early detection of fetal distress at lambing is essential to reduce mortality. Practicality and accuracy of pulse
oximetry to assess oxygenation status in newborn lambs under field conditions was evaluated. Oximetry was compared with blood gas analyses and included assessment of vitality (Apgar test) and vigour (attempt to and successful standing and suckling) of 135 Finnish by Polwarth lambs. Sampling of data was obtained immediately after fetal expulsion; percentage of oxygen saturation (satO2) was measured using a pulse oximeter clamped to an ear, and was compared with gas analyses variables measured from a jugular vein sample (Gas Analyser: SiemensRapidlab 248®). Correlations between satO2 measured by pulse oximetry and venous blood gas parameters either directly (partial pressure of carbon dioxide (pCO2), partial pressure of oxygen (pO2) and pH) or estimated
(bicarbonate concentration, extracellular fluid base excess, and oxygen saturation) were studied. Considering pH as a good indicator of hypoxia at parturition, data was grouped as: G1 = pH < 7.1; G2 = 7.1 ? pH < 7.2; G3 = 7.2 ? pH < 7.3 and G4 = pH ? 7.3. Saturation of oxygen measured by pulse oximetry correlated significantly with pCO2 (r = ? 0.50; P < 0.001), pH (r = 0.36; P < 0.001) and pO2 (r = 0.2, P = 0.04) measured by blood gas analyses. Lambs with low pH values (G1 = pH ? 7.1, acidosis) showed the lowest percentage to attempt and success to stand and suck, lowest Apgar score (G1 = 6.7, G2 = 8.6, G3 = 8.6, G4 = 8.5, P = 0.025), lowest percentage of satO2 measured by oximetry (G1 = 78.8%, G2 = 87.5%, G3 = 87.7%, G4 = 92.1%, P = 0.011) and
highest pCO2 (G1 = 78.5, G2 = 73.8, G3 = 65.8, G4 = 53.8 mmHg, P < 0.001). Pulse oximetry appears an accurate method to evaluate lamb birth asphyxia, helping to identify oxygenation constraints during labour, facilitating priority of perinatal handling, and thus improving lamb survival. MenosABSTRACT: Early detection of fetal distress at lambing is essential to reduce mortality. Practicality and accuracy of pulse
oximetry to assess oxygenation status in newborn lambs under field conditions was evaluated. Oximetry was compared with blood gas analyses and included assessment of vitality (Apgar test) and vigour (attempt to and successful standing and suckling) of 135 Finnish by Polwarth lambs. Sampling of data was obtained immediately after fetal expulsion; percentage of oxygen saturation (satO2) was measured using a pulse oximeter clamped to an ear, and was compared with gas analyses variables measured from a jugular vein sample (Gas Analyser: SiemensRapidlab 248®). Correlations between satO2 measured by pulse oximetry and venous blood gas parameters either directly (partial pressure of carbon dioxide (pCO2), partial pressure of oxygen (pO2) and pH) or estimated
(bicarbonate concentration, extracellular fluid base excess, and oxygen saturation) were studied. Considering pH as a good indicator of hypoxia at parturition, data was grouped as: G1 = pH < 7.1; G2 = 7.1 ? pH < 7.2; G3 = 7.2 ? pH < 7.3 and G4 = pH ? 7.3. Saturation of oxygen measured by pulse oximetry correlated significantly with pCO2 (r = ? 0.50; P < 0.001), pH (r = 0.36; P < 0.001) and pO2 (r = 0.2, P = 0.04) measured by blood gas analyses. Lambs with low pH values (G1 = pH ? 7.1, acidosis) showed the lowest percentage to attempt and success to stand and suck, lowest Apgar score (G1 = 6.7, G2 = 8.6, ... Presentar Todo |
|
Palabras claves : |
Blood gas analysis; Labour phase II; Lamb asphyxia; Ovine; Pulse oximetry. |
|
Thesagro : |
OVINOS. |
|
Asunto categoría : |
-- |
|
Marc : |
LEADER 02900naa a2200265 a 4500
001 1062844
005 2022-03-16
008 2022 bl uuuu u00u1 u #d
024 7 $a10.1016/j.smallrumres.2022.106665$2DOI
100 1 $aREGUEIRO, M.
245 $aComparison between pulse oximetry and venous blood gas analyses to assess lamb asphyxia at parturition.$h[electronic resource]
260 $c2022
500 $aArticle history: Received 28 June 2021; Received in revised form 2 March 2022; Accepted 3 March 2022; Available online 4 March 2022.
520 $aABSTRACT: Early detection of fetal distress at lambing is essential to reduce mortality. Practicality and accuracy of pulse oximetry to assess oxygenation status in newborn lambs under field conditions was evaluated. Oximetry was compared with blood gas analyses and included assessment of vitality (Apgar test) and vigour (attempt to and successful standing and suckling) of 135 Finnish by Polwarth lambs. Sampling of data was obtained immediately after fetal expulsion; percentage of oxygen saturation (satO2) was measured using a pulse oximeter clamped to an ear, and was compared with gas analyses variables measured from a jugular vein sample (Gas Analyser: SiemensRapidlab 248®). Correlations between satO2 measured by pulse oximetry and venous blood gas parameters either directly (partial pressure of carbon dioxide (pCO2), partial pressure of oxygen (pO2) and pH) or estimated (bicarbonate concentration, extracellular fluid base excess, and oxygen saturation) were studied. Considering pH as a good indicator of hypoxia at parturition, data was grouped as: G1 = pH < 7.1; G2 = 7.1 ? pH < 7.2; G3 = 7.2 ? pH < 7.3 and G4 = pH ? 7.3. Saturation of oxygen measured by pulse oximetry correlated significantly with pCO2 (r = ? 0.50; P < 0.001), pH (r = 0.36; P < 0.001) and pO2 (r = 0.2, P = 0.04) measured by blood gas analyses. Lambs with low pH values (G1 = pH ? 7.1, acidosis) showed the lowest percentage to attempt and success to stand and suck, lowest Apgar score (G1 = 6.7, G2 = 8.6, G3 = 8.6, G4 = 8.5, P = 0.025), lowest percentage of satO2 measured by oximetry (G1 = 78.8%, G2 = 87.5%, G3 = 87.7%, G4 = 92.1%, P = 0.011) and highest pCO2 (G1 = 78.5, G2 = 73.8, G3 = 65.8, G4 = 53.8 mmHg, P < 0.001). Pulse oximetry appears an accurate method to evaluate lamb birth asphyxia, helping to identify oxygenation constraints during labour, facilitating priority of perinatal handling, and thus improving lamb survival.
650 $aOVINOS
653 $aBlood gas analysis
653 $aLabour phase II
653 $aLamb asphyxia
653 $aOvine
653 $aPulse oximetry
700 1 $aJORGE-SMEDING, E.
700 1 $aSARAVIA, A.
700 1 $aLÓPEZ-MAZZ, C.
700 1 $aBANCHERO, G.
773 $tSmall Ruminant Research, 2022, Volume 21, Article number 106665. doi: https://doi.org/10.1016/j.smallrumres.2022.106665
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA La Estanzuela (LE) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
| Expresión de búsqueda válido. Check! |
|
|
