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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
01/10/2014 |
Actualizado : |
11/12/2018 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
LEMOS, M.V.A.; CHIAIA, H.L.J.; BERTON, M.P.; FEITOSA, F.L.B.; ABOUJAOUD, C.; CAMARGO, G.M.F.; PEREIRA, A.S.C.; ALBUQUERQUE, L.G.; FERRINHO, A.M.; MUELLER, L.F.; MAZALLI, M.R.; FURLAN, J.J.M.; CARVALHEIRO, R.; GORDO, D.M.; TONUSSI, R.; ESPIGOLAN, R.; SILVA, R.M.O.; DE OLIVEIRA, H.N.; DUCKETT, S.; AGUILAR, I.; BALDI, F. |
Afiliación : |
MARCOS V. A. LEMOS, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; HERMENEGILDO LUCAS JUSTINO CHIAIA, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; MARIANA PIATTO BERTON, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; FABIELI L. B. FEITOSA, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; CAROLYN ABOUJAOUD, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; GREGÓRIO M. F. CAMARGO, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; ANGÉLICA S. C. PEREIRA, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; LUCIA G. ALBUQUERQUE, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; ADRIELLE M. FERRINHO, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; LENISE F. MUELLER, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; MONICA R. MAZALLI, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; JOYCE J. M. FURLAN, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; ROBERTO CARVALHEIRO, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; DANIEL M. GORDO, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; RAFAEL TONUSSI, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; RAFAEL ESPIGOLAN, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; RAFAEL MEDEIROS DE OLIVEIRA SILVA, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; HENRIQUE NUNES DE OLIVEIRA, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; SUSAN DUCKETT, Department of Animal and Veterinary Science, Clemson University; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO BALDI, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista. |
Título : |
Genome-wide association between single nucleotide polymorphisms with beef fatty acid profile in Nellore cattle using the single step procedure. |
Fecha de publicación : |
2016 |
Fuente / Imprenta : |
BMC Genomics, 2016, v. 17:213. |
DOI : |
10.1186/s12864-016-2511-y |
Idioma : |
Inglés |
Notas : |
Received: 19 November 2015 / Accepted: 23 February 2016 /Published: 9 March 2016 |
Contenido : |
ABSTRACT.
Background: Saturated fatty acids can be detrimental to human health and have received considerable attention in recent years. Several studies using taurine breeds showed the existence of genetic variability and thus the possibility of genetic improvement of the fatty acid profile in beef. This study identified the regions of the genome associated with saturated, mono- and polyunsaturated fatty acids, and n-6 to n-3 ratios in the Longissimus thoracis of Nellore finished in feedlot, using the single-step method.
Results: The results showed that 115 windows explain more than 1 % of the additive genetic variance for the 22 studied fatty acids. Thirty-one genomic regions that explain more than 1 % of the additive genetic variance were observed for total saturated fatty acids, C12:0, C14:0, C16:0 and C18:0. Nineteen genomic regions, distributed in sixteen different chromosomes accounted for more than 1 % of the additive genetic variance for the monounsaturated fatty acids, such as the sum of monounsaturated fatty acids, C14:1 cis-9,
C18:1 trans-11, C18:1 cis-9, and C18:1 trans-9. Forty genomic regions explained more than 1 % of the additive variance for the polyunsaturated fatty acids group, which are related to the total polyunsaturated fatty acids, C20:4 n-6, C18:2 cis-9 cis12 n-6, C18:3 n-3, C18:3 n-6, C22:6 n-3 and C20:3 n-6 cis-8 cis-11 cis-14. Twenty-one genomic regions accounted for more than 1 % of the genetic variance for the group of omega-3, omega-6 and the n-6:n-3 ratio.
Conclusions: The identification of such regions and the respective candidate genes, such as ELOVL5, ESSRG, PCYT1A and genes of the ABC group (ABC5, ABC6 and ABC10), should contribute to form a genetic basis of the fatty acid profile of Nellore (Bos indicus) beef, contributing to better selection of the traits associated with improving human health.
© Lemos et al. 2016 MenosABSTRACT.
Background: Saturated fatty acids can be detrimental to human health and have received considerable attention in recent years. Several studies using taurine breeds showed the existence of genetic variability and thus the possibility of genetic improvement of the fatty acid profile in beef. This study identified the regions of the genome associated with saturated, mono- and polyunsaturated fatty acids, and n-6 to n-3 ratios in the Longissimus thoracis of Nellore finished in feedlot, using the single-step method.
Results: The results showed that 115 windows explain more than 1 % of the additive genetic variance for the 22 studied fatty acids. Thirty-one genomic regions that explain more than 1 % of the additive genetic variance were observed for total saturated fatty acids, C12:0, C14:0, C16:0 and C18:0. Nineteen genomic regions, distributed in sixteen different chromosomes accounted for more than 1 % of the additive genetic variance for the monounsaturated fatty acids, such as the sum of monounsaturated fatty acids, C14:1 cis-9,
C18:1 trans-11, C18:1 cis-9, and C18:1 trans-9. Forty genomic regions explained more than 1 % of the additive variance for the polyunsaturated fatty acids group, which are related to the total polyunsaturated fatty acids, C20:4 n-6, C18:2 cis-9 cis12 n-6, C18:3 n-3, C18:3 n-6, C22:6 n-3 and C20:3 n-6 cis-8 cis-11 cis-14. Twenty-one genomic regions accounted for more than 1 % of the genetic variance for the group of omega-3, omega-6 and the ... Presentar Todo |
Palabras claves : |
BOS INDICUS; FATTY ACID COMPOSITION; GENETIC MARKERS; HERITABILITY; SSGWAS. |
Thesagro : |
CEBU. |
Asunto categoría : |
-- |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/5871/1/Lemos-M.V.A.-2016.-BMC-Genomics.pdf
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2511-y
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Marc : |
LEADER 03229naa a2200457 a 4500 001 1050791 005 2018-12-11 008 2016 bl uuuu u00u1 u #d 024 7 $a10.1186/s12864-016-2511-y$2DOI 100 1 $aLEMOS, M.V.A. 245 $aGenome-wide association between single nucleotide polymorphisms with beef fatty acid profile in Nellore cattle using the single step procedure.$h[electronic resource] 260 $c2016 500 $aReceived: 19 November 2015 / Accepted: 23 February 2016 /Published: 9 March 2016 520 $aABSTRACT. Background: Saturated fatty acids can be detrimental to human health and have received considerable attention in recent years. Several studies using taurine breeds showed the existence of genetic variability and thus the possibility of genetic improvement of the fatty acid profile in beef. This study identified the regions of the genome associated with saturated, mono- and polyunsaturated fatty acids, and n-6 to n-3 ratios in the Longissimus thoracis of Nellore finished in feedlot, using the single-step method. Results: The results showed that 115 windows explain more than 1 % of the additive genetic variance for the 22 studied fatty acids. Thirty-one genomic regions that explain more than 1 % of the additive genetic variance were observed for total saturated fatty acids, C12:0, C14:0, C16:0 and C18:0. Nineteen genomic regions, distributed in sixteen different chromosomes accounted for more than 1 % of the additive genetic variance for the monounsaturated fatty acids, such as the sum of monounsaturated fatty acids, C14:1 cis-9, C18:1 trans-11, C18:1 cis-9, and C18:1 trans-9. Forty genomic regions explained more than 1 % of the additive variance for the polyunsaturated fatty acids group, which are related to the total polyunsaturated fatty acids, C20:4 n-6, C18:2 cis-9 cis12 n-6, C18:3 n-3, C18:3 n-6, C22:6 n-3 and C20:3 n-6 cis-8 cis-11 cis-14. Twenty-one genomic regions accounted for more than 1 % of the genetic variance for the group of omega-3, omega-6 and the n-6:n-3 ratio. Conclusions: The identification of such regions and the respective candidate genes, such as ELOVL5, ESSRG, PCYT1A and genes of the ABC group (ABC5, ABC6 and ABC10), should contribute to form a genetic basis of the fatty acid profile of Nellore (Bos indicus) beef, contributing to better selection of the traits associated with improving human health. © Lemos et al. 2016 650 $aCEBU 653 $aBOS INDICUS 653 $aFATTY ACID COMPOSITION 653 $aGENETIC MARKERS 653 $aHERITABILITY 653 $aSSGWAS 700 1 $aCHIAIA, H.L.J. 700 1 $aBERTON, M.P. 700 1 $aFEITOSA, F.L.B. 700 1 $aABOUJAOUD, C. 700 1 $aCAMARGO, G.M.F. 700 1 $aPEREIRA, A.S.C. 700 1 $aALBUQUERQUE, L.G. 700 1 $aFERRINHO, A.M. 700 1 $aMUELLER, L.F. 700 1 $aMAZALLI, M.R. 700 1 $aFURLAN, J.J.M. 700 1 $aCARVALHEIRO, R. 700 1 $aGORDO, D.M. 700 1 $aTONUSSI, R. 700 1 $aESPIGOLAN, R. 700 1 $aSILVA, R.M.O. 700 1 $aDE OLIVEIRA, H.N. 700 1 $aDUCKETT, S. 700 1 $aAGUILAR, I. 700 1 $aBALDI, F. 773 $tBMC Genomics, 2016$gv. 17:213.
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Registros recuperados : 6 | |
1. | | TONUSSI, R.L.; LONDOÑO-GIL, M.; DE OLIVEIRA SILVA, R.M.; MAGALHÃES, A.F.B.; AMORIM, S:T.; KLUSKA, S.; ESPIGOLAN, R.; PERIPOLLI, E.; PEREIRA, A.S.C.; LÔBO, R.B.; AGUILAR, I.; LOURENÇO, D.A.L.; BALDI, F. Accuracy of genomic breeding values and predictive ability for postweaning liveweight and age at first calving in a Nellore cattle population with missing sire information. Tropical Animal Health and Production, 2021, Volume 53, Issue 4, Article number 432. doi: https://doi.org/10.1007/s11250-021-02879-w Article history: Received 19 March 2021; Accepted 30 July 2021; Published online 10 August 2021.
Corresponding author: Londoño-Gil, M.; Grupo de Melhoramento Animal, Faculdade de Ciências Agrárias E Veterinárias, Universidade Estadual...Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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2. | | TONUSSI, R.L.; SILVA, R.M.O.; MAGALHÃES, A.F.B.; PERIPOLLI , E.; OLIVIERI, B.F.; FEITOSA, F.L.B.; PEREIR, A.S.C.; LÔBO, R.B.; MAGNABOSCO, C.U.; AGUILAR, I.; BALDI, F. Impact of multiple sire mating system on the accuracy of genomic breeding value prediction in a beef cattle population under selection . [abstract 206]. Issue Section: Breeding and Genetics. Journal of Animal Science. 2017, Volume 95, Issue Supplement 4, Page 102. https://doi.org/10.2527/asasann.2017.206 Article history: Published 01 August 2017. --Tipo: Abstracts/Resúmenes |
Biblioteca(s): INIA Las Brujas. |
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3. | | TONUSSI, R. L.; SILVA, R. M. D. O.; MAGALHÃES, A.F.B.; ESPIGOLAN, R.; PERIPOLLI, E.; OLIVIERI, B. F.; FEITOSA, F. L. B.; LEMOS, M. V. A.; BERTON, M. P.; CHIAIA, H. L. J.; PEREIRA, A. S. C.; LÔBO, R. B.; BEZERRA, L. A. F.; MAGNABOSCO, C. D. U.; LOURENÇO, D.A.L.; AGUILAR, I.; BALDI, F. Application of single step genomic BLUP under different uncertain paternity scenarios using simulated data. (Research article). PLoS ONE, September 2017, Volume 12, Issue 9, Article number e0181752. OPEN ACCESS. Article history: Received September 22, 2016 // Accepted July 6, 2017 // Published September 28, 2017.
Data Availability Statement: All relevant data are within the paper, its Supporting Information files, and in Figshare.
Funding: This...Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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4. | | LEMOS, M.V.A.; CHIAIA, H.L.J.; BERTON, M.P.; FEITOSA, F.L.B.; ABOUJAOUD, C.; CAMARGO, G.M.F.; PEREIRA, A.S.C.; ALBUQUERQUE, L.G.; FERRINHO, A.M.; MUELLER, L.F.; MAZALLI, M.R.; FURLAN, J.J.M.; CARVALHEIRO, R.; GORDO, D.M.; TONUSSI, R.; ESPIGOLAN, R.; SILVA, R.M.O.; DE OLIVEIRA, H.N.; DUCKETT, S.; AGUILAR, I.; BALDI, F. Genome-wide association between single nucleotide polymorphisms with beef fatty acid profile in Nellore cattle using the single step procedure. BMC Genomics, 2016, v. 17:213. Received: 19 November 2015 / Accepted: 23 February 2016 /Published: 9 March 2016Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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5. | | CHIAIA, H.L.J.; PERIPOLLI, E.; DE OLIVEIRA SILVA, R.M.; FEITOSA, F.L.B.; DE LEMOS, M.V.A.; BERTON, M.P.; OLIVIERI, B.F.; ESPIGOLAN, R.; TONUSSI, R.L.; GORDO, D.G.M.; DE ALBUQUERQUE, L.G.; DE OLIVEIRA, H.N.; FERRINHO, A.M.; MUELLER, L.F.; KLUSKA, S.; TONHATI, H.; PEREIRA, A.S.C.; AGUILAR, I.; BALDI, F. Genomic prediction ability for beef fatty acid profile in Nelore cattle using different pseudo-phenotypes. Journal of Applied Genetics, 1 November 2018, volume 59, Issue 4, pages 493-501. Article history: Received: 15 May 2018 // Revised: 28 August 2018 // Accepted: 17 September 2018.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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6. | | FEITOSA, F. L. B.; OLIVIERI, B. F.; ABOUJAOUDE, C.; PEREIRA, A. S. C.; DE LEMOS, M. V. A.; CHIAIA, H. L. J.; BERTON, M. P.; PERIPOLLI, E.; FERRINHO, A. M.; MUELLER, L. F.; MAZZALI, M. R.; DE ALBUQUERQUE, L. G.; DE OLIVERA, H. N.; TONHATI, H.; ESPIGOLAN, R.; TONUSSI, R. L.; DE OLIVIERA SILVA, R. M.; GORDO, D. G. M.; MAGALHAES, A. F. B.; AGUILAR, I.; BALDI, F. S. B. Genetic correlation estimates between beef fatty acid profile with meat and carcass traits in Nellore cattle finished in feedlot. Journal of Applied Genetics, 2017, 58 (1), 123-132. Article history: Received: 15 December 2015 /Revised: 10 March 2016 /Accepted: 5 July 2016 / Published Online: 30 July 2016Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
Biblioteca(s): INIA Las Brujas. |
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Registros recuperados : 6 | |
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