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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha : |
01/11/2018 |
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Actualizado : |
07/11/2018 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
ZARANTONELLI, L.; SUANES, A.; MENY, P.; BURONI, F.; SALVARREY,X.; BRIANO , C.; ASHFIELD, N.; SILVEIRA, C.S.; DUTRA, F.; EASTON, C.; FRAGA, M.; GIANNITTI, F.; HAMOND, C.; MACÍAS-RIOSECO, M.; MENÉNDEZ, C.; MORTOLA, A.; PICARDEAU, M. |
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Afiliación : |
LETICIA ZARANTONELLI, Laboratorio de Microbiología Molecular y Estructural, Institut Pasteur de Montevideo, Uruguay.; Unidad Mixta UMPI, Institut Pasteur de Montevideo; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay.; ALEJANDRA SUANES, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino" Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; PAULINA MENY, Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Uruguay.; FLORENCIA BURONI, División Laboratorios Veterinarios "Miguel C. Rubino" Laboratorio Regional Noroeste, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; XIMENA SALVARREY, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino". Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay .; CAROLINA BRIANO, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino" Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay .; NATALIA ASHFIELD4, Departamento de Bacteriología y Virologí, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Uruguay.; CAROLINE DA SILVA SILVEIRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO DUTRA, División Laboratorios Veterinarios "Miguel C. Rubino". Laboratorio Regional Este, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; CRISTINA EASTON, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino" Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; MARTIN FRAGA COTELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CAMILA HAMOND, Unidad Mixta UMPI, Institut Pasteur de Montevideo ; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MELISSA MACÍAS RIOSECO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CLARA MENÉNDEZ, Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Uruguay.; ALBERTO MORTOLA, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino" Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; MATHIEU PICARDEAU, Institut Pasteur de Montevideo, Uruguay. / Institut Pasteur, France. |
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Título : |
Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
PLoS Neglected Tropical Diseases, September 2018, vol. 12, Issue 9, Article number e0006694. OPEN ACCESS. |
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DOI : |
10.1371/journal.pntd.0006694 |
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Idioma : |
Inglés |
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Notas : |
Article History: Received: February 8, 2018; Accepted: July 16, 2018; Published: September 13, 2018. |
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Contenido : |
Abstract:
Leptospirosis is a neglected zoonosis with worldwide distribution. The causative agents are spirochete bacteria of the Leptospira genus, displaying huge diversity of serovars, the identity of which is critical for effective diagnosis and vaccination purposes. Among many other mammalian species, Leptospira infects cattle, eliciting acute signs in calves, and chronic disease in adult animals often leading to abortions. In South America, and including in Uruguay, beef and dairy export are leading sources of national income. Despite the importance of bovine health, food safety, and bovine-related dissemination of leptospirosis to humans, extremely limited information is available as to the identity of Leptospira species and serovars infecting cattle in Uruguay and the South American subcontinent. Here we report a multicentric 3-year study resulting in the isolation and detailed characterization of 40 strains of Leptospira spp. obtained from infected cattle. Combined serologic and molecular typing identified these isolates as L. interrogans serogroup Pomona serovar Kennewicki (20 strains), L. interrogans serogroup Canicola serovar Canicola (1 strain), L. borgpetersenii serogroup Sejroe serovar Hardjo (10 strains) and L. noguchii (9 strains). The latter showed remarkable phenotypic and genetic variability, belonging to 6 distinct serogroups, including 3 that did not react with a large panel of reference serogrouping antisera. Approximately 20% of cattle sampled in the field were found to be shedding pathogenic Leptospira in their urine, uncovering a threat for public health that is being largely neglected. The two L. interrogans serovars that we isolated from cattle displayed identical genetic signatures to those of human isolates that had previously been obtained from leptospirosis patients. This report of local Leptospira strains shall improve diagnostic tools and the understanding of leptospirosis epidemiology in South America. These strains could also be used as new components within bacterin vaccines to protect against the pathogenic Leptospira strains that are actually circulating, a direct measure to reduce the risk of human leptospirosis.
© 2018 Zarantonelli et al. http://creativecommons.org/licenses/by/4.0/. MenosAbstract:
Leptospirosis is a neglected zoonosis with worldwide distribution. The causative agents are spirochete bacteria of the Leptospira genus, displaying huge diversity of serovars, the identity of which is critical for effective diagnosis and vaccination purposes. Among many other mammalian species, Leptospira infects cattle, eliciting acute signs in calves, and chronic disease in adult animals often leading to abortions. In South America, and including in Uruguay, beef and dairy export are leading sources of national income. Despite the importance of bovine health, food safety, and bovine-related dissemination of leptospirosis to humans, extremely limited information is available as to the identity of Leptospira species and serovars infecting cattle in Uruguay and the South American subcontinent. Here we report a multicentric 3-year study resulting in the isolation and detailed characterization of 40 strains of Leptospira spp. obtained from infected cattle. Combined serologic and molecular typing identified these isolates as L. interrogans serogroup Pomona serovar Kennewicki (20 strains), L. interrogans serogroup Canicola serovar Canicola (1 strain), L. borgpetersenii serogroup Sejroe serovar Hardjo (10 strains) and L. noguchii (9 strains). The latter showed remarkable phenotypic and genetic variability, belonging to 6 distinct serogroups, including 3 that did not react with a large panel of reference serogrouping antisera. Approximately 20% of cattle sampled in the fi... Presentar Todo |
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Palabras claves : |
SALUD ANIMAL. |
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Thesagro : |
LEPTOSPIRA; LEPTOSPIROSIS. |
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Asunto categoría : |
-- |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/11772/1/Zarantonelli-2018-Isolation-of-pathogenic-leptospira-1.pdf
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Marc : |
LEADER 03472naa a2200373 a 4500
001 1059268
005 2018-11-07
008 2018 bl uuuu u00u1 u #d
024 7 $a10.1371/journal.pntd.0006694$2DOI
100 1 $aZARANTONELLI, L.
245 $aIsolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis.
260 $c2018
500 $aArticle History: Received: February 8, 2018; Accepted: July 16, 2018; Published: September 13, 2018.
520 $aAbstract: Leptospirosis is a neglected zoonosis with worldwide distribution. The causative agents are spirochete bacteria of the Leptospira genus, displaying huge diversity of serovars, the identity of which is critical for effective diagnosis and vaccination purposes. Among many other mammalian species, Leptospira infects cattle, eliciting acute signs in calves, and chronic disease in adult animals often leading to abortions. In South America, and including in Uruguay, beef and dairy export are leading sources of national income. Despite the importance of bovine health, food safety, and bovine-related dissemination of leptospirosis to humans, extremely limited information is available as to the identity of Leptospira species and serovars infecting cattle in Uruguay and the South American subcontinent. Here we report a multicentric 3-year study resulting in the isolation and detailed characterization of 40 strains of Leptospira spp. obtained from infected cattle. Combined serologic and molecular typing identified these isolates as L. interrogans serogroup Pomona serovar Kennewicki (20 strains), L. interrogans serogroup Canicola serovar Canicola (1 strain), L. borgpetersenii serogroup Sejroe serovar Hardjo (10 strains) and L. noguchii (9 strains). The latter showed remarkable phenotypic and genetic variability, belonging to 6 distinct serogroups, including 3 that did not react with a large panel of reference serogrouping antisera. Approximately 20% of cattle sampled in the field were found to be shedding pathogenic Leptospira in their urine, uncovering a threat for public health that is being largely neglected. The two L. interrogans serovars that we isolated from cattle displayed identical genetic signatures to those of human isolates that had previously been obtained from leptospirosis patients. This report of local Leptospira strains shall improve diagnostic tools and the understanding of leptospirosis epidemiology in South America. These strains could also be used as new components within bacterin vaccines to protect against the pathogenic Leptospira strains that are actually circulating, a direct measure to reduce the risk of human leptospirosis. © 2018 Zarantonelli et al. http://creativecommons.org/licenses/by/4.0/.
650 $aLEPTOSPIRA
650 $aLEPTOSPIROSIS
653 $aSALUD ANIMAL
700 1 $aSUANES, A.
700 1 $aMENY, P.
700 1 $aBURONI, F.
700 1 $aSALVARREY,X.
700 1 $aBRIANO , C.
700 1 $aASHFIELD, N.
700 1 $aSILVEIRA, C.S.
700 1 $aDUTRA, F.
700 1 $aEASTON, C.
700 1 $aFRAGA, M.
700 1 $aGIANNITTI, F.
700 1 $aHAMOND, C.
700 1 $aMACÍAS-RIOSECO, M.
700 1 $aMENÉNDEZ, C.
700 1 $aMORTOLA, A.
700 1 $aPICARDEAU, M.
773 $tPLoS Neglected Tropical Diseases, September 2018, vol. 12, Issue 9, Article number e0006694. OPEN ACCESS.
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Registro original : |
INIA La Estanzuela (LE) |
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| Registros recuperados : 50 | |
| 41. |  | DELPIAZZO, R.; BARCELLOS, M.; BARROS, S.; BENTANCOR, L.; FRAGA, M.; GIL, J.; IRAOLA, G.; MORSELLA, C.; PAOLICCHI, F.; PÉREZ, R.; RIET-CORREA, F.; SANGUINETTI, M.; SILVA, A.; SILVEIRA, C.S.; CALLEROS, L. Accurate and fast identification of Campylobacter fetus in bulls by real-time PCR targeting a 16S rRNA gene sequence. Veterinary and Animal Science, January 2021, vol.11 no. 100165, 5 p. OPEN ACCESS. Doi: https://doi.org/10.1016/j.vas.2020.100163 Article history: Received 21 October 2020 / Received in revised form 20 December 2020 / Accepted 22 December 2020 / available online 24 December 2020.
Corresponding author: laurabet@higiene.edu.uy| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Treinta y Tres. |
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| 42. | | MACÍAS-RIOSECO, M.; SILVEIRA, C.S.; FRAGA, M.; CASAUX, M.L.; CABRERA, A.; FRANCIA, M.E.; REBOLLO, C.; MAYA, L.; ZARANTONELLI, L.; SUANES, A.; COLINA, R.; BUSCHIAZZO, A.; GIANNITTI, F.; RIET-CORREA, F. Causes of abortion in dairy cows in Uruguay. [Causas de aborto em bovinos de leite no Uruguai]. Pesquisa Veterinaria Brasileira, 1 May 2020, Volume 40, Issue 5, Pages 325-332. OPEN ACCESS. DOI: https://doi.org/10.1590/1678-5150-pvb-6550 Article history: Received on December 3, 2019./Accepted for publication on December 26, 2019. This research was financially supported by Agencia Nacional de Investigación e Innovación (ANII), grant FSSA_X_2014_1_105696. The authors thank...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
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| 43. | | GIANNITTI, F.; SILVEIRA, C.S.; BULLOCK, H.; BERON, M.; FERNÁNDEZ-CIGANDA, S.; BENÍTEZ-GALEANO, M.J.; RODRÍGUEZ-OSORIO, N.; SILVA-FLANNERY, L.; PERDOMO, T.; CABRERA, A.; PUENTES, R.; COLINA, R.; RITTER, J.M.; CASTELLS, M. Bovine Polyomavirus-1 (Epsilonpolyomavirus bovis): An emerging fetal pathogen of cattle that causes renal lesions resembling Polyomavirus-associated nephropathy of humans. Viruses, 2022; 14 (9): 2042. OPEN ACCESS. doi: https://doi.org/10.3390/v14092042 Article history: Received 12 August 2022; Revised 8 September 2022: Accepted 9 September 2022; Published 14 September 2022.
Academic Editors: Fernando Bauermann and Mayara Maggioli.
Correspondence authors: Giannitti, F.; Plataforma de...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 44. | | DORSCH, M.; CASAUX, M.L.; CALLEROS, L.; ARÁOZ, V.; CAFFARENA, D.; MONESIGLIO, M.C.; BARCELLOS, M.; SILVEIRA, C.S.; PERDOMO, T.; BANCHERO, G.; UZAL, F.A.; FRAGA, M.; GIANNITTI, F. Corrigendum to "Placentitis and abortion caused by a multidrug resistant strain of Campylobacter fetus subspecies fetus in a sheep in Uruguay". (Revista Argentina de Microbiologia (2022) 54(1) (25-30), (S0325754121000389), (10.1016/j.ram.2021.02.005)). Erratum. Revista Argentina de Microbiologia. 2023, Volume 55, Issue 4, Pages 397-398. https://doi.org/10.1016/j.ram.2023.11.002 -- OPEN ACCESS. Article history: Available online 21 December 2023; Version of Record 21 December 2023. -- Correspondence: Giannitti, F.; Plataforma de Investigación en Salud Animal, Instituto Nacional de Investigación Agropecuaria (INIA), Ruta 50 Km 11,...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 45. | | GIANNITTI, F.; MACHADO, M.; SILVEIRA, C.S.; CIBILS-STEWART, X.; BARAIBAR, N.; QUEIROZ-MACHADO, C.R.R.; POPPENGA, R.H.; MENCHACA, A.; UZAL, F.A.; GARCÍA, J.A.; MATTO, C.; DUTRA, F.; RUPRECHTER, G.; CAFFARENA, D.; SARAVIA, A. Experimental oral administration of pollen beetle (Astylus atromaculatus) to cattle results in an acute lethal gastrointestinal disease. Research article. Veterinary Pathology. 2024. https://doi.org/10.1177/03009858241231557 -- [In Press] Article history: First published online March 4, 2024. -- Correspondence: Federico Giannitti, Plataforma de Investigación en Salud Animal, Instituto Nacional de Investigación Agropecuaria, Estación Experimental La Estanzuela, Ruta 50 km...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 46. | | CABRERA, A.; FRESIA, P.; BERNÁ, L.; SILVEIRA, C.S.; MACÍAS-RIOSECO, M.; AREVALO, A.P.; CRISPO, M.; PRITSCH, O.; RIET-CORREA, F.; GIANNITTI, F.; GIANNITTI, F.; FRANCIA, M.E.; ROBELLO, C. Isolation and molecular characterization of four novel Neospora caninum strains. Genetics, Evolution, and Phylogeny - Short Communication. Parasitology Research, 1 December 2019, Volume 118, Issue 12, Pages 3535-3542. Doi: 10.1007/s00436-019-06474-9 Article history: Received: 11 April 2019 / Accepted: 24 September 2019 / Published online: 7 November 2019.
Funding Sponsor: Agencia Nacional de Investigación e Innovación (ANII).
Funding Text: This project was funded by grant...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 47. | | ZARANTONELLI, L.; SUANES, A.; MENY, P.; BURONI, F.; SALVARREY,X.; BRIANO , C.; ASHFIELD, N.; SILVEIRA, C.S.; DUTRA, F.; EASTON, C.; FRAGA, M.; GIANNITTI, F.; HAMOND, C.; MACÍAS-RIOSECO, M.; MENÉNDEZ, C.; MORTOLA, A.; PICARDEAU, M. Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis. PLoS Neglected Tropical Diseases, September 2018, vol. 12, Issue 9, Article number e0006694. OPEN ACCESS. Article History: Received: February 8, 2018; Accepted: July 16, 2018; Published: September 13, 2018.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
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| 48. | | DORSCH, M.; CASAUX, M.L.; CALLEROS, L.; ARÁOZ, V.; CAFFARENA, D.; MONESIGLIO, M.C.; BARCELLOS, M; SILVEIRA, C.S.; PERDOMO, T.; BANCHERO, G.; UZAL, F.A.; FRAGA, M.; GIANNITTI, F. Placentitis and abortion caused by a multidrug resistant strain of Campylobacter fetus subspecies fetus in a sheep in Uruguay. Revista Argentina de Microbiología, 2022, volume 54, issue 1, pages 25-30. Open Acces. Doi:https://doi.org/10.1016/j.ram.2021.02.005 Article history: Received 22 July 2020/ Accepted 28 February 2021. Corresponding author:E-mail address: fgiannitti@inia.org.uy (F. Giannitti).
This work was financially supported by grants N-15156 PL 150 00 and PL 27 N-23398 of the...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
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| 49. | | DORSCH, M.; FRANCIA, M.E.; TANA, L.R.; GONZÁLEZ, F.C.; CABRERA, A.; CALLEROS, L.; SANGUINETTI, M.; BARCELLOS, M.; ZARANTONELLI, L; CIUFFO, C.; MAYA, L.; CASTELLS, M.; MIRAZO, S.; SILVEIRA, C.S.; RABAZA, A.; CAFFARENA, D.; DONCEL, B.; ARÁOZ, V.; MATTO, C.; RMENDANO, J.I.; SALADA, S.; FRAGA, M.; FIERRO, S.; GIANNITTI, F. Diagnostic investigation of 100 cases of abortion in sheep in Uruguay: 2015-2021. Frontiers in Veterinary Science, 2022; i. 9:904786. OPEN ACCESS. Doi: https://doi.org/10.3389/fvets.2022.904786. Article history: Received: 25 March 2022/Accepted: 13 April 2022/Published: 19 May 2022.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
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| 50. | | GIANNITTI, F.; FRANCIA, M.E.; TANA, L.; GONZÁLEZ, F.; CABRERA, A.; CALLEROS, L.; SANGUINETTI, M.; BARCELLOS, M.; ZARANTONELLI, L.; CIUFFO, C.; MAYA, L.; CASTELLS, M.; COLINA, R.; MIRAZO, S.; SILVEIRA, C.S.; RABAZA, A.; CAFFARENA, D.; DONCEL, B.; ARÁOZ, V.; MATTO, C.; ARMENDANO, J.; SALADA, S.; SARAVIA, A.; CASAUX, M.L.; SCHILD, C.; PERDOMO, Y.; FRAGA, M.; FIERRO, S.; DORSCH, M. Causas de aborto en ovinos de Uruguay: 100 casos, 2015-2021. Producción Animal. Revista INIA Uruguay, Setiembre 2022, no.70, p.18-22. (Revista INIA; 70). Agradecimientos: A todos los productores y técnicos del SUL y actividad liberal que enviaron casos al laboratorio y a los funcionarios de INIA, Institut Pasteur de Montevideo, Udelar y DILAVE que contribuyeron con los análisis de...| Tipo: Artículos en Revistas Agropecuarias |
| Biblioteca(s): INIA Las Brujas. |
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| Registros recuperados : 50 | |
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