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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela; INIA Las Brujas. |
Fecha : |
10/09/2014 |
Actualizado : |
06/11/2019 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
BRANDA, A.; RAVAGNOLO, O.; BRITO, G.; BALDI, F.; LA MANNA, A.; BANCHERO, G.; NAVAJAS, E.; RINCON, G.; MEDRANO, J.F. |
Afiliación : |
ANDREA BRANDA SICA, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay; OLGA RAVAGNOLO GUMILA, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay; GUSTAVO WALTER BRITO DIAZ, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay; ALEJANDRO FRANCISCO LA MANNA ALONSO, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay; GEORGGET ELIZABETH BANCHERO HUNZIKER, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay; ELLY ANA NAVAJAS VALENTINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Evaluation of panel SNP in metabolic pathways candidate genes for meat in hereford. [Evaluación de panel SNP en genes candidatos de vías metabólicas para carne en hereford.] |
Fecha de publicación : |
2014 |
Fuente / Imprenta : |
Archivos de Zootecnia, 2014, v.63, no.241, p.73-84. OPEN ACCESS |
ISSN : |
0004-0592 |
DOI : |
10.4321/S0004-05922014000100008 |
Idioma : |
Español |
Notas : |
Article history: Recibido 12 noviembre 2012 // Aceptado 25 setiembre 2013. |
Contenido : |
RESUMEN.
Se realizó una validación preliminar de un panel de marcadores SNP seleccionados de genes candidatos, relacionados al eje endócrino que regulan la hormona de crecimiento GH/IGF1, y a la formación y desaturación de ácidos grasos SCD/SREBP1, con características de composición de canal, calidad de carne y perfil de ácidos grasos de la grasa intramuscular en novillos Hereford sometidos a diferentes tratamientos de alimentación durante la etapa de recría y engorde intensivo. Se ajustaron las variables por el efecto de los 8 tratamientos nutricionales y se calcularon los valores residuales para los análisis de asociación con los marcadores SNP. Se determinó un total de 11 696 genotipos de 237 novillos utilizando un panel de 58 tag-SNP en los genes GHR, IGF1, IGFBP6, PMCH, SOCS2, STAT6, SCD1, SCD5, SREBP1, SCAP, INSIG1, INSIG2, MBTPS1, MBTPS2 y SRPR, de los cuales se encontraron 11 SNP polimórficos que estuvieron asociados signifi-cativamente: GHR_ rs41639262 sobre EGSu y MARBL; IGF1_ rs136251088 sobre PCC, PCE y PISTOLA; PMCH_ rs135033882 sobre OMEGA36; SOCS2_ ss252841026 sobre Terneza2d; STAT6_ rs109171041 sobre Terneza2d; STAT6_ rs110097583 sobre Terneza2d; INSIG1_ rs109314460 sobre Terneza21d; INSIG1_ ss252452220 sobre OMEGA36; SCD5_ ss252452202 sobre PUFA y Terneza2d; SCD5_ rs43687655 sobre EGSu y OMEGA36; SRPR_ rs42178091 sobre GRASAINTR, SFA, MUFA, PCC, PCE y PISTOLA. Estudios adicionales podrían confirmar estos efectos, posibilitando mejorar la calidad de la canal y de la carne, de animales sometidos a diferentes tratamientos de alimentación a través de la selección.
SUMMARY.
The phenotype-genotype associations of a panel of SNP markers selected from candidate genes related to the growth hormone GH/IGF1endocrine axis and the fatty acid synthesis and desaturation SCD/SREBP1 pathways, were examined. Phenotypes of interest were carcass composition, meat quality and fatty acid profiles of intramuscular fat in Hereford steers under different feeding treatments during the growth and finishing stages. Variables were adjusted for the effect of eight nutritional treatments and residual values were used in the association analysis with the SNP markers. A total of 11 696 genotypes of 237 steers were determined using a panel of 58 tag-SNP in the GHR, IGF1, IGFBP6, PMCH, SOCS2, STAT6, SCD1, SCD5, SREBP1, SCAP, INSIG1, INSIG2, MBTPS1, MBTPS2 and SRPR genes. A total of 11 polymorphic SNP were significantly asso-ciated with traits of interest: GHR_ rs41639262 on EGSu and MARBL; IGF1_ rs136251088 on PCC, PCE and PISTOLA; PMCH_ rs135033882 on OMEGA36; SOCS2_ ss252841026 on Terneza2d; STAT6_ rs109171041 on Terneza2d; STAT6_ rs110097583 on Terneza2d; INSIG1_ rs109314460 on Terneza21d; INSIG1_ ss252452220 on OMEGA36; SCD5_ ss252452202 on PUFA and Terneza2d; SCD5_ rs43687655 on EGSu and OMEGA36; SRPR_ rs42178091 on GRASAINTR, SFA, MUFA, PCC, PCE and PISTOLA. Additional studies could validate the marker-trait association effects that would make it possible to use these genetic markers to improve carcass and meat quality of animals under different feeding regimes. MenosRESUMEN.
Se realizó una validación preliminar de un panel de marcadores SNP seleccionados de genes candidatos, relacionados al eje endócrino que regulan la hormona de crecimiento GH/IGF1, y a la formación y desaturación de ácidos grasos SCD/SREBP1, con características de composición de canal, calidad de carne y perfil de ácidos grasos de la grasa intramuscular en novillos Hereford sometidos a diferentes tratamientos de alimentación durante la etapa de recría y engorde intensivo. Se ajustaron las variables por el efecto de los 8 tratamientos nutricionales y se calcularon los valores residuales para los análisis de asociación con los marcadores SNP. Se determinó un total de 11 696 genotipos de 237 novillos utilizando un panel de 58 tag-SNP en los genes GHR, IGF1, IGFBP6, PMCH, SOCS2, STAT6, SCD1, SCD5, SREBP1, SCAP, INSIG1, INSIG2, MBTPS1, MBTPS2 y SRPR, de los cuales se encontraron 11 SNP polimórficos que estuvieron asociados signifi-cativamente: GHR_ rs41639262 sobre EGSu y MARBL; IGF1_ rs136251088 sobre PCC, PCE y PISTOLA; PMCH_ rs135033882 sobre OMEGA36; SOCS2_ ss252841026 sobre Terneza2d; STAT6_ rs109171041 sobre Terneza2d; STAT6_ rs110097583 sobre Terneza2d; INSIG1_ rs109314460 sobre Terneza21d; INSIG1_ ss252452220 sobre OMEGA36; SCD5_ ss252452202 sobre PUFA y Terneza2d; SCD5_ rs43687655 sobre EGSu y OMEGA36; SRPR_ rs42178091 sobre GRASAINTR, SFA, MUFA, PCC, PCE y PISTOLA. Estudios adicionales podrían confirmar estos efectos, posibilitando mejorar la calidad de la canal ... Presentar Todo |
Palabras claves : |
BEEF CATTLE; CARCASS COMPOSITION; FATTY ACID PROFILE; MEAT QUALITY. |
Thesagro : |
CALIDAD DE LA CARNE; COMPOSICIÓN DE LA CANAL; DESTETE PRECOZ; GANADO DE CARNE; HORMONAS; NUTRICIÓN ANIMAL; PERFIL DE ÁCIDOS GRASOS; PUBERTAD. |
Asunto categoría : |
L01 Ganadería |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/3071/1/Branda-A.-2014-Archivos-Zootecnia-v.63241-p.73-84.pdf
http://www.uco.es/organiza/servicios/publica/az/php/img/web/27_19_11_08_2870EvaluacionBranda.pdf
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Marc : |
LEADER 04383nam a2200385 a 4500 001 1050122 005 2019-11-06 008 2014 bl uuuu u0uu1 u #d 022 $a0004-0592 024 7 $a10.4321/S0004-05922014000100008$2DOI 100 1 $aBRANDA, A. 245 $aEvaluation of panel SNP in metabolic pathways candidate genes for meat in hereford. [Evaluación de panel SNP en genes candidatos de vías metabólicas para carne en hereford.]$h[electronic resource] 260 $aArchivos de Zootecnia, 2014, v.63, no.241, p.73-84. OPEN ACCESS$c2014 500 $aArticle history: Recibido 12 noviembre 2012 // Aceptado 25 setiembre 2013. 520 $aRESUMEN. Se realizó una validación preliminar de un panel de marcadores SNP seleccionados de genes candidatos, relacionados al eje endócrino que regulan la hormona de crecimiento GH/IGF1, y a la formación y desaturación de ácidos grasos SCD/SREBP1, con características de composición de canal, calidad de carne y perfil de ácidos grasos de la grasa intramuscular en novillos Hereford sometidos a diferentes tratamientos de alimentación durante la etapa de recría y engorde intensivo. Se ajustaron las variables por el efecto de los 8 tratamientos nutricionales y se calcularon los valores residuales para los análisis de asociación con los marcadores SNP. Se determinó un total de 11 696 genotipos de 237 novillos utilizando un panel de 58 tag-SNP en los genes GHR, IGF1, IGFBP6, PMCH, SOCS2, STAT6, SCD1, SCD5, SREBP1, SCAP, INSIG1, INSIG2, MBTPS1, MBTPS2 y SRPR, de los cuales se encontraron 11 SNP polimórficos que estuvieron asociados signifi-cativamente: GHR_ rs41639262 sobre EGSu y MARBL; IGF1_ rs136251088 sobre PCC, PCE y PISTOLA; PMCH_ rs135033882 sobre OMEGA36; SOCS2_ ss252841026 sobre Terneza2d; STAT6_ rs109171041 sobre Terneza2d; STAT6_ rs110097583 sobre Terneza2d; INSIG1_ rs109314460 sobre Terneza21d; INSIG1_ ss252452220 sobre OMEGA36; SCD5_ ss252452202 sobre PUFA y Terneza2d; SCD5_ rs43687655 sobre EGSu y OMEGA36; SRPR_ rs42178091 sobre GRASAINTR, SFA, MUFA, PCC, PCE y PISTOLA. Estudios adicionales podrían confirmar estos efectos, posibilitando mejorar la calidad de la canal y de la carne, de animales sometidos a diferentes tratamientos de alimentación a través de la selección. SUMMARY. The phenotype-genotype associations of a panel of SNP markers selected from candidate genes related to the growth hormone GH/IGF1endocrine axis and the fatty acid synthesis and desaturation SCD/SREBP1 pathways, were examined. Phenotypes of interest were carcass composition, meat quality and fatty acid profiles of intramuscular fat in Hereford steers under different feeding treatments during the growth and finishing stages. Variables were adjusted for the effect of eight nutritional treatments and residual values were used in the association analysis with the SNP markers. A total of 11 696 genotypes of 237 steers were determined using a panel of 58 tag-SNP in the GHR, IGF1, IGFBP6, PMCH, SOCS2, STAT6, SCD1, SCD5, SREBP1, SCAP, INSIG1, INSIG2, MBTPS1, MBTPS2 and SRPR genes. A total of 11 polymorphic SNP were significantly asso-ciated with traits of interest: GHR_ rs41639262 on EGSu and MARBL; IGF1_ rs136251088 on PCC, PCE and PISTOLA; PMCH_ rs135033882 on OMEGA36; SOCS2_ ss252841026 on Terneza2d; STAT6_ rs109171041 on Terneza2d; STAT6_ rs110097583 on Terneza2d; INSIG1_ rs109314460 on Terneza21d; INSIG1_ ss252452220 on OMEGA36; SCD5_ ss252452202 on PUFA and Terneza2d; SCD5_ rs43687655 on EGSu and OMEGA36; SRPR_ rs42178091 on GRASAINTR, SFA, MUFA, PCC, PCE and PISTOLA. Additional studies could validate the marker-trait association effects that would make it possible to use these genetic markers to improve carcass and meat quality of animals under different feeding regimes. 650 $aCALIDAD DE LA CARNE 650 $aCOMPOSICIÓN DE LA CANAL 650 $aDESTETE PRECOZ 650 $aGANADO DE CARNE 650 $aHORMONAS 650 $aNUTRICIÓN ANIMAL 650 $aPERFIL DE ÁCIDOS GRASOS 650 $aPUBERTAD 653 $aBEEF CATTLE 653 $aCARCASS COMPOSITION 653 $aFATTY ACID PROFILE 653 $aMEAT QUALITY 700 1 $aRAVAGNOLO, O. 700 1 $aBRITO, G. 700 1 $aBALDI, F. 700 1 $aLA MANNA, A. 700 1 $aBANCHERO, G. 700 1 $aNAVAJAS, E. 700 1 $aRINCON, G. 700 1 $aMEDRANO, J.F.
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INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
Fecha actual : |
25/05/2020 |
Actualizado : |
25/05/2020 |
Autor : |
ESCANDÓN, B.M.; ESPINOZA, J.S.; PEREA, F.P.; FERNANDO QUITO, F.; OCHOA, R.; LÓPEZ, G.E.; GALARZA, D.A.; GARZÓN, J. P. |
Afiliación : |
BYRON M. ESCANDÓN, Escandón Escuela de Medicina Veterinaria y Zootecnia, Facultad de Ciencias Agropecuarias, Universidad de Cuenca, Av. 12 de Octubre y Menéndez y Pelayo, 010205, Cuenca, Azuay, Ecuador.; JUAN S. ESPINOZA, Escuela de Medicina Veterinaria y Zootecnia, Facultad de Ciencias Agropecuarias, Universidad de Cuenca, Av. 12 de Octubre y Menéndez y Pelayo, 010205, Cuenca, Azuay, Ecuador.; FERNANDO P. PEREA, Departamento de Ciencias Agrarias, Universidad de Los Andes, Trujillo, Venezuela.; FERNANDO QUITO, Libre ejercicio de la profesión, Cuenca, Azuay, Ecuador.; RAFAEL OCHOA, Escuela de Medicina Veterinaria y Zootecnia, Facultad de Ciencias Agropecuarias, Universidad de Cuenca, Av. 12 de Octubre y Menéndez y Pelayo, 010205, Cuenca, Azuay, Ecuador.; GONZALO E. LÓPEZ, Escuela de Medicina Veterinaria y Zootecnia, Facultad de Ciencias Agropecuarias, Universidad de Cuenca, Av. 12 de Octubre y Menéndez y Pelayo, 010205, Cuenca, Azuay, Ecuador.; DIEGO A. GALARZA, Escuela de Medicina Veterinaria y Zootecnia, Facultad de Ciencias Agropecuarias, Universidad de Cuenca, Av. 12 de Octubre y Menéndez y Pelayo, 010205, Cuenca, Azuay, Ecuador.; JUAN PABLO GARZÓN PRADO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay./Instituto Nacional de Investigaciones Agropecuarias (INIAP),Ecuador./Centro Latinoamericano de Estudios de Problemáticas Lecheras (CLEPL),Facultad de Ciencias Veterinarias,Argentina. |
Título : |
Intrauterine therapy with ozone reduces subclinical endometritis and improves reproductive performance in postpartum dairy cows managed in pasture-based systems. |
Fecha de publicación : |
2020 |
Fuente / Imprenta : |
Tropical Animal Health Production,2020. DOI: https://doi.org/10.1007/s11250-020-02298-3 |
Idioma : |
Inglés |
Notas : |
Article history: Received06 December 2019// Accepted13 May 2020// Published22 May 2020. The research was supported by Dirección de Investigación de la Universidad de Cuenca (DIUC), Ecuador, throughout project DIUC-XIV-2016-022.The authors thank the Department of Research and Development of ?La Colina Cia. Ltda? for the contribution for the contribution to this research. In addition, the authors thank Dr. Gustavo Antunes, ?La Estanzuela? experimental station, National Institute of Agricultural Research, INIA, Uruguay, and Dr. Adolfo Toledano-Díaz, Department of Animal Reproduction, INIA, Spain for the critical reading of this manuscript. |
Contenido : |
Abstract:
New postpartum strategies have been developed in dairy cows to ameliorate uterine health and reproductive performance, especially the first service conception rates. This study aimed to assess the effect of intrauterine therapy with ozone (IUTO) in early postpartum on subclinical endometritis prevalence and reproductive parameters in dairy cows under commercial farm conditions. For this purpose, eighty clinically healthy cows with a body condition score between 3.0 and 3.5, from four dairy farms, were randomly allocated into two groups: ozone therapy group (OG, n?=?40), which were subjected to IUTO, and control group (CG, n?=?40). Content of uterine polymorphonuclear (PMN) leukocytes and subclinical endometritis (SE) percentage were assessed at 35 days after calving by uterine cytology. A second cytology was performed 72 h after IUTO. Reproductive parameters such as interval calving to first service (IFS), number of services per conception (nSC), interval calving to conception (ICC) and first service conception rate (FSCR) were analysed. The second endometrial cytology demonstrated that IUTO reduced (P?0.01) both PMN (3.7?±?1.4 vs. 7.6?±?1.1%) and SE (5.0 vs. 50.0%) percentages compared with CG. Likewise, after ozone treatment, both nSC (2.1?±?0.3 vs. 3.1?±?0.2; P?0.01) and ICC (126.2?±?9.7 vs. 149.0?±?9.0; P?=?0.0672) decreased, and FSCR increased (50.0 vs. 16.2%; P?0.01) compared with CG. In conclusion, intrauterine ozone therapy applied at 35 days after calving reduced subclinical endometritis prevalence and improved reproductive performance in postpartum dairy cows managed in a pasture-based system. MenosAbstract:
New postpartum strategies have been developed in dairy cows to ameliorate uterine health and reproductive performance, especially the first service conception rates. This study aimed to assess the effect of intrauterine therapy with ozone (IUTO) in early postpartum on subclinical endometritis prevalence and reproductive parameters in dairy cows under commercial farm conditions. For this purpose, eighty clinically healthy cows with a body condition score between 3.0 and 3.5, from four dairy farms, were randomly allocated into two groups: ozone therapy group (OG, n?=?40), which were subjected to IUTO, and control group (CG, n?=?40). Content of uterine polymorphonuclear (PMN) leukocytes and subclinical endometritis (SE) percentage were assessed at 35 days after calving by uterine cytology. A second cytology was performed 72 h after IUTO. Reproductive parameters such as interval calving to first service (IFS), number of services per conception (nSC), interval calving to conception (ICC) and first service conception rate (FSCR) were analysed. The second endometrial cytology demonstrated that IUTO reduced (P?0.01) both PMN (3.7?±?1.4 vs. 7.6?±?1.1%) and SE (5.0 vs. 50.0%) percentages compared with CG. Likewise, after ozone treatment, both nSC (2.1?±?0.3 vs. 3.1?±?0.2; P?0.01) and ICC (126.2?±?9.7 vs. 149.0?±?9.0; P?=?0.0672) decreased, and FSCR increased (50.0 vs. 16.2%; P?0.01) compared with CG. In conclusion, intrauterine ozone therapy applied at 35 days after ca... Presentar Todo |
Palabras claves : |
OZONE THERAPY; PLATAFORMA SALUD ANIMAL; PMN; REPRODUCTIVE PERFORMANCE; SUBCLINICAL ENDOMETRITIS. |
Asunto categoría : |
-- |
Marc : |
LEADER 03195naa a2200277 a 4500 001 1061084 005 2020-05-25 008 2020 bl uuuu u00u1 u #d 100 1 $aESCANDÓN, B.M. 245 $aIntrauterine therapy with ozone reduces subclinical endometritis and improves reproductive performance in postpartum dairy cows managed in pasture-based systems.$h[electronic resource] 260 $c2020 500 $aArticle history: Received06 December 2019// Accepted13 May 2020// Published22 May 2020. The research was supported by Dirección de Investigación de la Universidad de Cuenca (DIUC), Ecuador, throughout project DIUC-XIV-2016-022.The authors thank the Department of Research and Development of ?La Colina Cia. Ltda? for the contribution for the contribution to this research. In addition, the authors thank Dr. Gustavo Antunes, ?La Estanzuela? experimental station, National Institute of Agricultural Research, INIA, Uruguay, and Dr. Adolfo Toledano-Díaz, Department of Animal Reproduction, INIA, Spain for the critical reading of this manuscript. 520 $aAbstract: New postpartum strategies have been developed in dairy cows to ameliorate uterine health and reproductive performance, especially the first service conception rates. This study aimed to assess the effect of intrauterine therapy with ozone (IUTO) in early postpartum on subclinical endometritis prevalence and reproductive parameters in dairy cows under commercial farm conditions. For this purpose, eighty clinically healthy cows with a body condition score between 3.0 and 3.5, from four dairy farms, were randomly allocated into two groups: ozone therapy group (OG, n?=?40), which were subjected to IUTO, and control group (CG, n?=?40). Content of uterine polymorphonuclear (PMN) leukocytes and subclinical endometritis (SE) percentage were assessed at 35 days after calving by uterine cytology. A second cytology was performed 72 h after IUTO. Reproductive parameters such as interval calving to first service (IFS), number of services per conception (nSC), interval calving to conception (ICC) and first service conception rate (FSCR) were analysed. The second endometrial cytology demonstrated that IUTO reduced (P?0.01) both PMN (3.7?±?1.4 vs. 7.6?±?1.1%) and SE (5.0 vs. 50.0%) percentages compared with CG. Likewise, after ozone treatment, both nSC (2.1?±?0.3 vs. 3.1?±?0.2; P?0.01) and ICC (126.2?±?9.7 vs. 149.0?±?9.0; P?=?0.0672) decreased, and FSCR increased (50.0 vs. 16.2%; P?0.01) compared with CG. In conclusion, intrauterine ozone therapy applied at 35 days after calving reduced subclinical endometritis prevalence and improved reproductive performance in postpartum dairy cows managed in a pasture-based system. 653 $aOZONE THERAPY 653 $aPLATAFORMA SALUD ANIMAL 653 $aPMN 653 $aREPRODUCTIVE PERFORMANCE 653 $aSUBCLINICAL ENDOMETRITIS 700 1 $aESPINOZA, J.S. 700 1 $aPEREA, F.P. 700 1 $aFERNANDO QUITO, F. 700 1 $aOCHOA, R. 700 1 $aLÓPEZ, G.E. 700 1 $aGALARZA, D.A. 700 1 $aGARZÓN, J. P. 773 $tTropical Animal Health Production,2020. DOI: https://doi.org/10.1007/s11250-020-02298-3
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