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Registro completo
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Biblioteca (s) : |
INIA Tacuarembó. |
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Fecha : |
09/04/2021 |
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Actualizado : |
09/04/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
QUEIROZ, C.R.R.; MACHADO, M.; BROMBERGER, C.R; OLIVEIRA-FILHO, J.P.; BORGES, A.S.; SOTO-BLANCO, B.; BORGES, J.R.J.; CÂMARA, A.C.L.; CASTRO, M.B.D. |
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Afiliación : |
CINTIA REGINA RÊGO QUEIROZ, Veterinary Pathology Laboratory, University of Brasília, Campus Darcy Ribeiro, Brasília, Brazil; MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CRISTIANA RAACH BROMBERGER, Department of Veterinary Clinical Science, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil; JOSE PAES OLIVEIRA-FILHO, Department of Veterinary Clinical Science, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil; ALEXANDRE SECORUN BORGES, 3 Department of Veterinary Clinical Science, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil; BENITO SOTO-BLANCO, Department of Veterinary Clinics and Surgery, Veterinary College, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; JOSÉ RENATO JUNQUEIRA BORGES, 5 College of Agronomy and Veterinary Medicine, Large Animal Veterinary Teaching Hospital, University of Brasília, Brasília, Brazil; ANTÔNIO CARLOS LOPES CÂMARA, College of Agronomy and Veterinary Medicine, Large Animal Veterinary Teaching Hospital, University of Brasília, Brasília, Brazil; MÁRCIO BOTELHO DE CASTRO, Veterinary Pathology Laboratory, University of Brasília, Campus Darcy Ribeiro, Brasília, Brazil. |
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Título : |
Case report: A possible case of congenital Erythropoietic Porphyria in a gir calf: a clinical, pathological, and molecular approach. |
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Fecha de publicación : |
2021 |
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Fuente / Imprenta : |
Frontiers in Veterinary Science, 12 March 2021, Volume 8, Article number 632762. OPEN ACCESS. Doi: https://doi.org/10.3389/fvets.2021.632762 |
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DOI : |
10.3389/fvets.2021.632762 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received: 24 November 2020; Accepted: 05 February 2021; Published: 12 March 2021. |
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Contenido : |
Congenital erythropoietic porphyria (CEP) is a rare hereditary autosomal recessive disease which has never been reported in Zebu cattle. A 3-day-old Gir calf showed teeth discoloration, fever, dehydration, and dyspnea. The main gross findings were pink-colored teeth, red-brown periosteum and bone marrow, and a fluorescent bright pink coloration of the bone marrow and articular surfaces under ultraviolet light. Aggregates of periodic acid-Schiff (PAS)-stained porphyrin pigments were evident in the lungs, kidneys, and the liver. An intron 8 single-nucleotide polymorphism (SNP) in both the Gir calf and control animals, along with the absence of the uroporphyrin III synthetase (UROS) gene mutation, was observed. Most SNPs were located in the intron regions of the UROS gene without relevance for CEP. A continuous loss of genetic variability and an increase in inbreeding in some herds may be related to CEP in Gir cattle, one of the most prominent Zebu breeds worldwide. In summary, this study describes a presumptive case of CEP in a Gir calf based on clinical and pathological findings. A definitive diagnosis
would require the measurement of porphyrin levels in blood, urine, or tissues or the identification of UROS gene defects. |
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Palabras claves : |
CATTLE; PINK TEETH; PORPHYRIN; UROPORPHYRIN; VETERINARY; ZEBU. |
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Asunto categoría : |
L70 Ciencias veterinarias e higiene - Aspectos generales |
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URL : |
https://www.frontiersin.org/articles/10.3389/fvets.2021.632762/pdf
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Marc : |
LEADER 02328naa a2200313 a 4500
001 1061968
005 2021-04-09
008 2021 bl uuuu u00u1 u #d
024 7 $a10.3389/fvets.2021.632762$2DOI
100 1 $aQUEIROZ, C.R.R.
245 $aCase report$bA possible case of congenital Erythropoietic Porphyria in a gir calf: a clinical, pathological, and molecular approach.$h[electronic resource]
260 $c2021
500 $aArticle history: Received: 24 November 2020; Accepted: 05 February 2021; Published: 12 March 2021.
520 $aCongenital erythropoietic porphyria (CEP) is a rare hereditary autosomal recessive disease which has never been reported in Zebu cattle. A 3-day-old Gir calf showed teeth discoloration, fever, dehydration, and dyspnea. The main gross findings were pink-colored teeth, red-brown periosteum and bone marrow, and a fluorescent bright pink coloration of the bone marrow and articular surfaces under ultraviolet light. Aggregates of periodic acid-Schiff (PAS)-stained porphyrin pigments were evident in the lungs, kidneys, and the liver. An intron 8 single-nucleotide polymorphism (SNP) in both the Gir calf and control animals, along with the absence of the uroporphyrin III synthetase (UROS) gene mutation, was observed. Most SNPs were located in the intron regions of the UROS gene without relevance for CEP. A continuous loss of genetic variability and an increase in inbreeding in some herds may be related to CEP in Gir cattle, one of the most prominent Zebu breeds worldwide. In summary, this study describes a presumptive case of CEP in a Gir calf based on clinical and pathological findings. A definitive diagnosis would require the measurement of porphyrin levels in blood, urine, or tissues or the identification of UROS gene defects.
653 $aCATTLE
653 $aPINK TEETH
653 $aPORPHYRIN
653 $aUROPORPHYRIN
653 $aVETERINARY
653 $aZEBU
700 1 $aMACHADO, M.
700 1 $aBROMBERGER, C.R
700 1 $aOLIVEIRA-FILHO, J.P.
700 1 $aBORGES, A.S.
700 1 $aSOTO-BLANCO, B.
700 1 $aBORGES, J.R.J.
700 1 $aCÂMARA, A.C.L.
700 1 $aCASTRO, M.B.D.
773 $tFrontiers in Veterinary Science, 12 March 2021, Volume 8, Article number 632762. OPEN ACCESS. Doi: https://doi.org/10.3389/fvets.2021.632762
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INIA Tacuarembó (TBO) |
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Registro completo
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Biblioteca (s) : |
INIA Treinta y Tres. |
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Fecha actual : |
22/12/2020 |
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Actualizado : |
12/03/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
-- - -- |
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Autor : |
FORT, S.; FERREIRA, V.; MURCHIO, S.; SCHVARTZMAN, C.; GALVÁN, G.A.; VILARÓ, F.; SIRI, M.I.; DALLA RIZZA, M. |
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Afiliación : |
S. FORT, Universidad de la República, Facultad de Química. Laboratorio de Microbiología Molecular, Uruguay.; V. FERREIRA, Universidad de la República, Facultad de Química. Laboratorio de Microbiología Molecular, Uruguay.; MARIA SARA MURCHIO VIGNOLO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CLAUDIA SCHVARTZMAN DISEGNI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; G.A. GALVÁN, Universidad de la República. Facultad de Agronomía. Departamento de Producción Vegetal.; F. VILARÓ, Universidad de la República. Facultad de Agronomía. Departamento de Producción Vegetal.; M.I. SIRI, Universidad de la República. Facultad de Química. Laboratorio de Microbiología Molecular.; MARCO DALLA RIZZA VILARO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Potato plants transformed with the Arabidopsis EF-Tu receptor (EFR) show restricted pathogen colonization and enhanced bacterial with resistance under conditions resembling natural field infections. [Plantas de papa transformadas con el receptor de EF-Tu (EFR) de Arabidopsis presentan una colonización restringida del patógeno y mayor resistencia a la marchitez Bacteriana bajo condiciones semejantes a la infección natural de campo]. |
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Complemento del título : |
Special Issue X Encuentro Latinoamericano y del Caribe de Biotecnología Agropecuaria; XII Simposio REDBIO Argentina. Roca, William, Ed. 12 al 15 de noviembre de 2019, Montevideo, Uruguay. |
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Fecha de publicación : |
2020 |
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Fuente / Imprenta : |
Agrociencia Uruguay 2020, v. 24, no. NE2, Article 413. DOI: 10.31285/AGRO.24.413 |
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Páginas : |
16 p. |
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Serie : |
2301-1548 |
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DOI : |
10.31285/AGRO.24.413 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 29 Jun. 2020 // Accepted 28 Sep. 2020 // Published 17 Dec 2020.
Comité científico editor:
Dra. Marisa López-Bilbao (INTA, Hurlingham, Provincia de Buenos Aires, Argentina); Dra. Sandra Sharry (Universidad Nacional de la Plata, La Plata, Buenos Aires, Argentina); Dra. Alicia Castillo (Investigadora Principal, Unidad de Biotecnología de INIA, Uruguay) ; Dr. Juan Izquierdo (Profesor Libre Facultad de Agronomía, Udelar, Presidente Academia Chilena Ciencias Agronómicas) ; Dr. Gerardo Gallego (Coordinador del Laboratorio de Biotecnología Vegetal del Centro Internacional de Agricultura Tropical-CIAT Cali, Colombia) ; Dra. Elizabeth Hodson (Profesora emérita de la Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia); Dr. Paul Chavarriaga (líder de la plataforma de transformación genética y edición de genomas del Centro Internacional de Agricultura Tropical-CIAT Cali, Colombia) ; Dr. Marco Dalla-Rizza (Coordinador de la Unidad de Biotecnología, Investigador principal referente, presidente REDBIO 2016-2020). |
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Contenido : |
Potato is considered a staple food in the world and its production is limited by the presence of bacterial wilt (BW) disease caused by Ralstonia solanacearum. Host resistance is the most sustainable and cost-effective strategy to manage BW, although resistant commercial potato cultivars are not yet available. Our group incorporated the EFR receptor of Arabidopsis thaliana(AtEFR), which recognizes the elongation factor Tu, preserved in bacteria, triggering an immune response. AtEFR was tested in two genetic backgrounds: a susceptible commercial cultivar (INIA Iporá) and a breeding clone with partial resistance introgressed from Solanum commersonii. In this work, the effect of the AtEFR receptor on BW resistance was evaluated for the first time, using conditions resembling natural field infection. In addition, the colonization patterns of wild-type and transgenic lines were compared by using luminescent and fluorescent R. solanacearum reporter strains. Both approaches showed a delay and a decrease in the severity of wilting symptoms in the AtEFR-transformed genotypes. Differential colonization pat-terns were observed, revealing a higher bacterial development in the non-transformed plants. ThisAtEFR effect seems more pronounced in the interspecific breeding line, possibly leading to a more effective activation of the plant immune system. |
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Palabras claves : |
BACTERIAL WILT; EF-Tu RECEPTOR; MARCHITEZ BACTERIANA; PAMP TRIGGERED IMMUNITY; PAPA TRANSGENICA; POLYGENIC RESISTANCE; RESISTENCIA MEDIADA POR PAMP; RESISTENCIA POLIGÉNICA; TRANSGENIC POTATO. |
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Asunto categoría : |
H20 Enfermedades de las plantas |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/14913/1/Fort-2020-Agrociencia.pdf
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Marc : |
LEADER 03834naa a2200361 a 4500
001 1061634
005 2021-03-12
008 2020 bl uuuu u00u1 u #d
024 7 $a10.31285/AGRO.24.413$2DOI
100 1 $aFORT, S.
245 $aPotato plants transformed with the Arabidopsis EF-Tu receptor (EFR) show restricted pathogen colonization and enhanced bacterial with resistance under conditions resembling natural field infections. [Plantas de papa transformadas con el receptor de EF-Tu (EFR) de Arabidopsis presentan una colonización restringida del patógeno y mayor resistencia a la marchitez Bacteriana bajo condiciones semejantes a la infección natural de campo].$h[electronic resource]
260 $c2020
300 $a16 p.
490 $a2301-1548
500 $aArticle history: Received 29 Jun. 2020 // Accepted 28 Sep. 2020 // Published 17 Dec 2020. Comité científico editor: Dra. Marisa López-Bilbao (INTA, Hurlingham, Provincia de Buenos Aires, Argentina); Dra. Sandra Sharry (Universidad Nacional de la Plata, La Plata, Buenos Aires, Argentina); Dra. Alicia Castillo (Investigadora Principal, Unidad de Biotecnología de INIA, Uruguay) ; Dr. Juan Izquierdo (Profesor Libre Facultad de Agronomía, Udelar, Presidente Academia Chilena Ciencias Agronómicas) ; Dr. Gerardo Gallego (Coordinador del Laboratorio de Biotecnología Vegetal del Centro Internacional de Agricultura Tropical-CIAT Cali, Colombia) ; Dra. Elizabeth Hodson (Profesora emérita de la Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Colombia); Dr. Paul Chavarriaga (líder de la plataforma de transformación genética y edición de genomas del Centro Internacional de Agricultura Tropical-CIAT Cali, Colombia) ; Dr. Marco Dalla-Rizza (Coordinador de la Unidad de Biotecnología, Investigador principal referente, presidente REDBIO 2016-2020).
520 $aPotato is considered a staple food in the world and its production is limited by the presence of bacterial wilt (BW) disease caused by Ralstonia solanacearum. Host resistance is the most sustainable and cost-effective strategy to manage BW, although resistant commercial potato cultivars are not yet available. Our group incorporated the EFR receptor of Arabidopsis thaliana(AtEFR), which recognizes the elongation factor Tu, preserved in bacteria, triggering an immune response. AtEFR was tested in two genetic backgrounds: a susceptible commercial cultivar (INIA Iporá) and a breeding clone with partial resistance introgressed from Solanum commersonii. In this work, the effect of the AtEFR receptor on BW resistance was evaluated for the first time, using conditions resembling natural field infection. In addition, the colonization patterns of wild-type and transgenic lines were compared by using luminescent and fluorescent R. solanacearum reporter strains. Both approaches showed a delay and a decrease in the severity of wilting symptoms in the AtEFR-transformed genotypes. Differential colonization pat-terns were observed, revealing a higher bacterial development in the non-transformed plants. ThisAtEFR effect seems more pronounced in the interspecific breeding line, possibly leading to a more effective activation of the plant immune system.
653 $aBACTERIAL WILT
653 $aEF-Tu RECEPTOR
653 $aMARCHITEZ BACTERIANA
653 $aPAMP TRIGGERED IMMUNITY
653 $aPAPA TRANSGENICA
653 $aPOLYGENIC RESISTANCE
653 $aRESISTENCIA MEDIADA POR PAMP
653 $aRESISTENCIA POLIGÉNICA
653 $aTRANSGENIC POTATO
700 1 $aFERREIRA, V.
700 1 $aMURCHIO, S.
700 1 $aSCHVARTZMAN, C.
700 1 $aGALVÁN, G.A.
700 1 $aVILARÓ, F.
700 1 $aSIRI, M.I.
700 1 $aDALLA RIZZA, M.
773 $tAgrociencia Uruguay 2020$gv. 24, no. NE2, Article 413. DOI: 10.31285/AGRO.24.413
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