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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
01/10/2014 |
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Actualizado : |
11/12/2018 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
LEMOS, M.V.A.; CHIAIA, H.L.J.; BERTON, M.P.; FEITOSA, F.L.B.; ABOUJAOUD, C.; CAMARGO, G.M.F.; PEREIRA, A.S.C.; ALBUQUERQUE, L.G.; FERRINHO, A.M.; MUELLER, L.F.; MAZALLI, M.R.; FURLAN, J.J.M.; CARVALHEIRO, R.; GORDO, D.M.; TONUSSI, R.; ESPIGOLAN, R.; SILVA, R.M.O.; DE OLIVEIRA, H.N.; DUCKETT, S.; AGUILAR, I.; BALDI, F. |
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Afiliación : |
MARCOS V. A. LEMOS, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; HERMENEGILDO LUCAS JUSTINO CHIAIA, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; MARIANA PIATTO BERTON, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; FABIELI L. B. FEITOSA, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; CAROLYN ABOUJAOUD, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; GREGÓRIO M. F. CAMARGO, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; ANGÉLICA S. C. PEREIRA, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; LUCIA G. ALBUQUERQUE, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; ADRIELLE M. FERRINHO, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; LENISE F. MUELLER, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; MONICA R. MAZALLI, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; JOYCE J. M. FURLAN, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo; ROBERTO CARVALHEIRO, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; DANIEL M. GORDO, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; RAFAEL TONUSSI, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; RAFAEL ESPIGOLAN, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; RAFAEL MEDEIROS DE OLIVEIRA SILVA, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; HENRIQUE NUNES DE OLIVEIRA, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista; SUSAN DUCKETT, Department of Animal and Veterinary Science, Clemson University; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO BALDI, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista. |
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Título : |
Genome-wide association between single nucleotide polymorphisms with beef fatty acid profile in Nellore cattle using the single step procedure. |
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Fecha de publicación : |
2016 |
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Fuente / Imprenta : |
BMC Genomics, 2016, v. 17:213. |
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DOI : |
10.1186/s12864-016-2511-y |
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Idioma : |
Inglés |
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Notas : |
Received: 19 November 2015 / Accepted: 23 February 2016 /Published: 9 March 2016 |
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Contenido : |
ABSTRACT.
Background: Saturated fatty acids can be detrimental to human health and have received considerable attention in recent years. Several studies using taurine breeds showed the existence of genetic variability and thus the possibility of genetic improvement of the fatty acid profile in beef. This study identified the regions of the genome associated with saturated, mono- and polyunsaturated fatty acids, and n-6 to n-3 ratios in the Longissimus thoracis of Nellore finished in feedlot, using the single-step method.
Results: The results showed that 115 windows explain more than 1 % of the additive genetic variance for the 22 studied fatty acids. Thirty-one genomic regions that explain more than 1 % of the additive genetic variance were observed for total saturated fatty acids, C12:0, C14:0, C16:0 and C18:0. Nineteen genomic regions, distributed in sixteen different chromosomes accounted for more than 1 % of the additive genetic variance for the monounsaturated fatty acids, such as the sum of monounsaturated fatty acids, C14:1 cis-9,
C18:1 trans-11, C18:1 cis-9, and C18:1 trans-9. Forty genomic regions explained more than 1 % of the additive variance for the polyunsaturated fatty acids group, which are related to the total polyunsaturated fatty acids, C20:4 n-6, C18:2 cis-9 cis12 n-6, C18:3 n-3, C18:3 n-6, C22:6 n-3 and C20:3 n-6 cis-8 cis-11 cis-14. Twenty-one genomic regions accounted for more than 1 % of the genetic variance for the group of omega-3, omega-6 and the n-6:n-3 ratio.
Conclusions: The identification of such regions and the respective candidate genes, such as ELOVL5, ESSRG, PCYT1A and genes of the ABC group (ABC5, ABC6 and ABC10), should contribute to form a genetic basis of the fatty acid profile of Nellore (Bos indicus) beef, contributing to better selection of the traits associated with improving human health.
© Lemos et al. 2016 MenosABSTRACT.
Background: Saturated fatty acids can be detrimental to human health and have received considerable attention in recent years. Several studies using taurine breeds showed the existence of genetic variability and thus the possibility of genetic improvement of the fatty acid profile in beef. This study identified the regions of the genome associated with saturated, mono- and polyunsaturated fatty acids, and n-6 to n-3 ratios in the Longissimus thoracis of Nellore finished in feedlot, using the single-step method.
Results: The results showed that 115 windows explain more than 1 % of the additive genetic variance for the 22 studied fatty acids. Thirty-one genomic regions that explain more than 1 % of the additive genetic variance were observed for total saturated fatty acids, C12:0, C14:0, C16:0 and C18:0. Nineteen genomic regions, distributed in sixteen different chromosomes accounted for more than 1 % of the additive genetic variance for the monounsaturated fatty acids, such as the sum of monounsaturated fatty acids, C14:1 cis-9,
C18:1 trans-11, C18:1 cis-9, and C18:1 trans-9. Forty genomic regions explained more than 1 % of the additive variance for the polyunsaturated fatty acids group, which are related to the total polyunsaturated fatty acids, C20:4 n-6, C18:2 cis-9 cis12 n-6, C18:3 n-3, C18:3 n-6, C22:6 n-3 and C20:3 n-6 cis-8 cis-11 cis-14. Twenty-one genomic regions accounted for more than 1 % of the genetic variance for the group of omega-3, omega-6 and the ... Presentar Todo |
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Palabras claves : |
BOS INDICUS; FATTY ACID COMPOSITION; GENETIC MARKERS; HERITABILITY; SSGWAS. |
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Thesagro : |
CEBU. |
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Asunto categoría : |
-- |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/5871/1/Lemos-M.V.A.-2016.-BMC-Genomics.pdf
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2511-y
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Marc : |
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024 7 $a10.1186/s12864-016-2511-y$2DOI
100 1 $aLEMOS, M.V.A.
245 $aGenome-wide association between single nucleotide polymorphisms with beef fatty acid profile in Nellore cattle using the single step procedure.$h[electronic resource]
260 $c2016
500 $aReceived: 19 November 2015 / Accepted: 23 February 2016 /Published: 9 March 2016
520 $aABSTRACT. Background: Saturated fatty acids can be detrimental to human health and have received considerable attention in recent years. Several studies using taurine breeds showed the existence of genetic variability and thus the possibility of genetic improvement of the fatty acid profile in beef. This study identified the regions of the genome associated with saturated, mono- and polyunsaturated fatty acids, and n-6 to n-3 ratios in the Longissimus thoracis of Nellore finished in feedlot, using the single-step method. Results: The results showed that 115 windows explain more than 1 % of the additive genetic variance for the 22 studied fatty acids. Thirty-one genomic regions that explain more than 1 % of the additive genetic variance were observed for total saturated fatty acids, C12:0, C14:0, C16:0 and C18:0. Nineteen genomic regions, distributed in sixteen different chromosomes accounted for more than 1 % of the additive genetic variance for the monounsaturated fatty acids, such as the sum of monounsaturated fatty acids, C14:1 cis-9, C18:1 trans-11, C18:1 cis-9, and C18:1 trans-9. Forty genomic regions explained more than 1 % of the additive variance for the polyunsaturated fatty acids group, which are related to the total polyunsaturated fatty acids, C20:4 n-6, C18:2 cis-9 cis12 n-6, C18:3 n-3, C18:3 n-6, C22:6 n-3 and C20:3 n-6 cis-8 cis-11 cis-14. Twenty-one genomic regions accounted for more than 1 % of the genetic variance for the group of omega-3, omega-6 and the n-6:n-3 ratio. Conclusions: The identification of such regions and the respective candidate genes, such as ELOVL5, ESSRG, PCYT1A and genes of the ABC group (ABC5, ABC6 and ABC10), should contribute to form a genetic basis of the fatty acid profile of Nellore (Bos indicus) beef, contributing to better selection of the traits associated with improving human health. © Lemos et al. 2016
650 $aCEBU
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700 1 $aFEITOSA, F.L.B.
700 1 $aABOUJAOUD, C.
700 1 $aCAMARGO, G.M.F.
700 1 $aPEREIRA, A.S.C.
700 1 $aALBUQUERQUE, L.G.
700 1 $aFERRINHO, A.M.
700 1 $aMUELLER, L.F.
700 1 $aMAZALLI, M.R.
700 1 $aFURLAN, J.J.M.
700 1 $aCARVALHEIRO, R.
700 1 $aGORDO, D.M.
700 1 $aTONUSSI, R.
700 1 $aESPIGOLAN, R.
700 1 $aSILVA, R.M.O.
700 1 $aDE OLIVEIRA, H.N.
700 1 $aDUCKETT, S.
700 1 $aAGUILAR, I.
700 1 $aBALDI, F.
773 $tBMC Genomics, 2016$gv. 17:213.
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Registro original : |
INIA Las Brujas (LB) |
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| Registros recuperados : 8 | |
| 1. |  | BERTON, M.P.; SILVA, R.P; CARVALHO, F.E.; CHIAIA HLJ.; OLIVEIRA, PS.; ELER, JP.; BANCHERO, G.; FERRAZ, JBS; BALDI, F. Genetic parameter estimates for gastrointestinal nematode parasite resistance and maternal efficiency indicator traits in Santa Inês breed. Journal Of Animal Breeding And Genetics = Zeitschrift Fur Tierzuchtung Und Zuchtungsbiologie 2019 Nov, Vol. 136 (6), p. 495-504. DOI: https://doi.org/10.1111/jbg.12424 Article history: Date of Electronic Publication: 2019 jul| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
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| 2. | | BERTON, M. P.; DA SILVA, ROSIANE PEREIRA; BANCHERO, G.; MOURÃO, G. B.; FERRAZ, J. B. S.; SCHENKEL, F. S.; BALDI, F. Genomic integration to identify molecular biomarkers associated with indicator traits of gastrointestinal nematode resistance in sheep. Journal of Animal Breeding and Genetics, 2022, Volume 139, Issue 5, pages 502-516. doi: https://doi.org/10.1111/jbg.12682 Article history: Received 14 June 2021; Accepted 21 April 2022; First published 09 May 2022; Publisched online September 2022. -- Corresponding author: Berton, M.P.; Departamento de Zootecnia, Faculdade de Ciências Agrárias e...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela; INIA Las Brujas. |
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| 3. | | SILVA, R.P.; ESPIGOLAN, R.; BERTON, M.P.; STAFUZZA, N.B.; SANTOS, F.S.; NEGREIROS, M.P.; SCHUCHMANN, R.K.; RODRIGUEZ, J.D.; LÔBO, R.B.; BANCHERO, G.; PEREIRA, A.S.C.; BERGMANN, J.A.G.; BALDI, F. Genetic parameters and genomic regions associated with calving ease in primiparous Nellore heifers. Livestock Science, October 2020, Volume 240, Article number 104183. Doi: https://doi.org/10.1016/j.livsci.2020.104183 Article history: Received 19 February 2020 /Received in revised form 25 June 2020 /Accepted 1 August 2020/Available online 02 August 2020. /Corresponding author: E-mail address: fernandobaldiuy@gmail.com (F. Baldi). This work was...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
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| 4. | | CARVALHO, F.E.; ESPIGOLAN, R.; BERTON, M.P.; NETO, J.B.S.; SILVA, R.P.; GRIGOLETTO, L.; SILVA, R.M.O.; FERRAZ, J.B.S.; ELER, J.P.; AGUILAR, I.; LÔBO, R.B.; BALDI, F. Genome-wide association study and predictive ability for growth traits in Nellore cattle. Livestock Science, January 2020, Volume 231, Article number 103861. OPEN ACCESS. Doi: https://doi.org/10.1016/j.livsci.2019.103861 Article history: Received 25 June 2019 / Revised 29 October 2019 / Accepted 4 November 2019 / Available online 6 November 2019.
Funding information: F.E. CARVALHO received a scholarship from Coordinating for the Improvement of Higher...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 5. | | TONUSSI, R. L.; SILVA, R. M. D. O.; MAGALHÃES, A.F.B.; ESPIGOLAN, R.; PERIPOLLI, E.; OLIVIERI, B. F.; FEITOSA, F. L. B.; LEMOS, M. V. A.; BERTON, M. P.; CHIAIA, H. L. J.; PEREIRA, A. S. C.; LÔBO, R. B.; BEZERRA, L. A. F.; MAGNABOSCO, C. D. U.; LOURENÇO, D.A.L.; AGUILAR, I.; BALDI, F. Application of single step genomic BLUP under different uncertain paternity scenarios using simulated data. (Research article). PLoS ONE, September 2017, Volume 12, Issue 9, Article number e0181752. OPEN ACCESS. Article history: Received September 22, 2016 // Accepted July 6, 2017 // Published September 28, 2017.
Data Availability Statement: All relevant data are within the paper, its Supporting Information files, and in Figshare.
Funding: This...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 6. | | LEMOS, M.V.A.; CHIAIA, H.L.J.; BERTON, M.P.; FEITOSA, F.L.B.; ABOUJAOUD, C.; CAMARGO, G.M.F.; PEREIRA, A.S.C.; ALBUQUERQUE, L.G.; FERRINHO, A.M.; MUELLER, L.F.; MAZALLI, M.R.; FURLAN, J.J.M.; CARVALHEIRO, R.; GORDO, D.M.; TONUSSI, R.; ESPIGOLAN, R.; SILVA, R.M.O.; DE OLIVEIRA, H.N.; DUCKETT, S.; AGUILAR, I.; BALDI, F. Genome-wide association between single nucleotide polymorphisms with beef fatty acid profile in Nellore cattle using the single step procedure. BMC Genomics, 2016, v. 17:213. Received: 19 November 2015 / Accepted: 23 February 2016 /Published: 9 March 2016| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 7. | | CHIAIA, H.L.J.; PERIPOLLI, E.; DE OLIVEIRA SILVA, R.M.; FEITOSA, F.L.B.; DE LEMOS, M.V.A.; BERTON, M.P.; OLIVIERI, B.F.; ESPIGOLAN, R.; TONUSSI, R.L.; GORDO, D.G.M.; DE ALBUQUERQUE, L.G.; DE OLIVEIRA, H.N.; FERRINHO, A.M.; MUELLER, L.F.; KLUSKA, S.; TONHATI, H.; PEREIRA, A.S.C.; AGUILAR, I.; BALDI, F. Genomic prediction ability for beef fatty acid profile in Nelore cattle using different pseudo-phenotypes. Journal of Applied Genetics, 1 November 2018, volume 59, Issue 4, pages 493-501. Article history: Received: 15 May 2018 // Revised: 28 August 2018 // Accepted: 17 September 2018.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 8. | | FEITOSA, F. L. B.; OLIVIERI, B. F.; ABOUJAOUDE, C.; PEREIRA, A. S. C.; DE LEMOS, M. V. A.; CHIAIA, H. L. J.; BERTON, M. P.; PERIPOLLI, E.; FERRINHO, A. M.; MUELLER, L. F.; MAZZALI, M. R.; DE ALBUQUERQUE, L. G.; DE OLIVERA, H. N.; TONHATI, H.; ESPIGOLAN, R.; TONUSSI, R. L.; DE OLIVIERA SILVA, R. M.; GORDO, D. G. M.; MAGALHAES, A. F. B.; AGUILAR, I.; BALDI, F. S. B. Genetic correlation estimates between beef fatty acid profile with meat and carcass traits in Nellore cattle finished in feedlot. Journal of Applied Genetics, 2017, 58 (1), 123-132. Article history: Received: 15 December 2015 /Revised: 10 March 2016 /Accepted: 5 July 2016 / Published Online: 30 July 2016| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| Registros recuperados : 8 | |
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