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Registro completo
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Biblioteca (s) : |
INIA Treinta y Tres. |
Fecha : |
08/01/2021 |
Actualizado : |
02/09/2022 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
ANTONIOS, S.; RODRÍGUEZ-RAMILO, S.T.; AGUILAR, I.; ASTRUC, J.M.; LEGARRA, A.; VITEZICA, Z. G. |
Afiliación : |
S. ANTONIOS, GenPhySE, INPT, INRAE, ENVTG, Tolosan, France; S. T. RODRÍGUEZ-RAMILO, GenPhySE, INPT, INRAE, ENVTG, Tolosan, France; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; J.M. ASTRUC, Institut de I'Elevage, Paris, France.; A. LEGARRA, GenPhySE, INPT, INRAE, ENVTG, Tolosan, France; Z. G. VITEZICA, GenPhySE, INPT, INRAE, ENVTG, Tolosan, France. |
Título : |
Genomic and pedigree estimation of inbreeding depression for semen traits in the Basco-Béarnaise dairy sheep breed. |
Fecha de publicación : |
2021 |
Fuente / Imprenta : |
Journal of Dairy Science, 2021, volume 104, number 3, pages 3221-3230. doi: https://doi.org/10.3168/jds.2020-18761 |
DOI : |
10.3168/jds.2020-18761 |
Idioma : |
Inglés |
Notas : |
Article history: Receibed: April 21, 2020 / Accepted: October 5, 2020 /First Publication: 23 Decembrer 2020.
Corresponding author: zulma.viterica@inrae.fr |
Contenido : |
Abstract
Inbreeding depression is associated with a decrease in performance and fitness of the animals. The goal of this study was to evaluate pedigree-based and genomic methods to estimate the level of inbreeding and inbreeding depression for 3 semen traits (volume, concentration, and motility score) in the Basco-Béarnaise sheep breed. Data comprised 16,196 (or 15,071)
phenotypic records from 620 rams (of which 533 rams had genotypes of 36,464 SNPs). The pedigree included 8,266 animals, composed of the 620 rams and their ancestors. The number of equivalent complete generations for the 620 rams was 7.04. Inbreeding coefficients were estimated using genomic and pedigree-based information. Genomic inbreeding coefficients were estimated from individual SNP and using segments of homozygous SNP (runs of homozygosity, ROH). Short ROH are of old origin, whereas long ROH are due to recent
inbreeding. Considering that the equivalent number of generations in Basco-Béarnaise was 6, inbreeding coefficients for ROH with a length >4 Mb refer to all (recent + old) inbreeding, those with a length >17 Mb correspond to recent inbreeding, and the difference between them indicates old inbreeding. Pedigree-based inbreeding coefficients were also estimated classically, or accounting for nonzero relationships for unknown parents, or including metafounder relationships (estimated using markers) to account for missing pedigree
information. Finally, inbreeding coefficients combining genotyped and nongenotyped animal information were computed from matrix H of the single-step approach, also including metafounders. Inbreeding depression was estimated differently depending on the approach used to compute inbreeding coefficients. These 8 estimators of inbreeding coefficients were included as covariates in different animal models. No inbreeding depression was detected for sperm volume or sperm concentration.
Inbreeding depression was significant for the motility of spermatozoa. The effect of old and recent inbreeding on motility was null and negative, respectively, demonstrating the existence of purging by selection of deleterious recessive alleles affecting motility. A 10% increase in inbreeding would result in a reduction in mean motility ranging between 0.09 and 0.22 points in the score (from 0 to 5). Motility is unfavorably affected by increasing recent inbreeding but the impact is very small. Runs of homozygosity and metafounders allow us to accurately estimate inbreeding depression and detect recent inbreeding . MenosAbstract
Inbreeding depression is associated with a decrease in performance and fitness of the animals. The goal of this study was to evaluate pedigree-based and genomic methods to estimate the level of inbreeding and inbreeding depression for 3 semen traits (volume, concentration, and motility score) in the Basco-Béarnaise sheep breed. Data comprised 16,196 (or 15,071)
phenotypic records from 620 rams (of which 533 rams had genotypes of 36,464 SNPs). The pedigree included 8,266 animals, composed of the 620 rams and their ancestors. The number of equivalent complete generations for the 620 rams was 7.04. Inbreeding coefficients were estimated using genomic and pedigree-based information. Genomic inbreeding coefficients were estimated from individual SNP and using segments of homozygous SNP (runs of homozygosity, ROH). Short ROH are of old origin, whereas long ROH are due to recent
inbreeding. Considering that the equivalent number of generations in Basco-Béarnaise was 6, inbreeding coefficients for ROH with a length >4 Mb refer to all (recent + old) inbreeding, those with a length >17 Mb correspond to recent inbreeding, and the difference between them indicates old inbreeding. Pedigree-based inbreeding coefficients were also estimated classically, or accounting for nonzero relationships for unknown parents, or including metafounder relationships (estimated using markers) to account for missing pedigree
information. Finally, inbreeding coefficients combining genotyped and non... Presentar Todo |
Palabras claves : |
BASCO-BÉARNAISE SHEEP; INBREEDING DEPRESSION; METAFOUNDER; RUNS OF HOMOZYGOSITY (ROH); SEMEN TRAIT; SHEEP BREEDING. |
Asunto categoría : |
L10 Genética y mejoramiento animal |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16655/1/Journal-Dairy-Science-2021-Antonios.pdf
|
Marc : |
LEADER 03588naa a2200277 a 4500 001 1061660 005 2022-09-02 008 2021 bl uuuu u00u1 u #d 024 7 $a10.3168/jds.2020-18761$2DOI 100 1 $aANTONIOS, S. 245 $aGenomic and pedigree estimation of inbreeding depression for semen traits in the Basco-Béarnaise dairy sheep breed.$h[electronic resource] 260 $c2021 500 $aArticle history: Receibed: April 21, 2020 / Accepted: October 5, 2020 /First Publication: 23 Decembrer 2020. Corresponding author: zulma.viterica@inrae.fr 520 $aAbstract Inbreeding depression is associated with a decrease in performance and fitness of the animals. The goal of this study was to evaluate pedigree-based and genomic methods to estimate the level of inbreeding and inbreeding depression for 3 semen traits (volume, concentration, and motility score) in the Basco-Béarnaise sheep breed. Data comprised 16,196 (or 15,071) phenotypic records from 620 rams (of which 533 rams had genotypes of 36,464 SNPs). The pedigree included 8,266 animals, composed of the 620 rams and their ancestors. The number of equivalent complete generations for the 620 rams was 7.04. Inbreeding coefficients were estimated using genomic and pedigree-based information. Genomic inbreeding coefficients were estimated from individual SNP and using segments of homozygous SNP (runs of homozygosity, ROH). Short ROH are of old origin, whereas long ROH are due to recent inbreeding. Considering that the equivalent number of generations in Basco-Béarnaise was 6, inbreeding coefficients for ROH with a length >4 Mb refer to all (recent + old) inbreeding, those with a length >17 Mb correspond to recent inbreeding, and the difference between them indicates old inbreeding. Pedigree-based inbreeding coefficients were also estimated classically, or accounting for nonzero relationships for unknown parents, or including metafounder relationships (estimated using markers) to account for missing pedigree information. Finally, inbreeding coefficients combining genotyped and nongenotyped animal information were computed from matrix H of the single-step approach, also including metafounders. Inbreeding depression was estimated differently depending on the approach used to compute inbreeding coefficients. These 8 estimators of inbreeding coefficients were included as covariates in different animal models. No inbreeding depression was detected for sperm volume or sperm concentration. Inbreeding depression was significant for the motility of spermatozoa. The effect of old and recent inbreeding on motility was null and negative, respectively, demonstrating the existence of purging by selection of deleterious recessive alleles affecting motility. A 10% increase in inbreeding would result in a reduction in mean motility ranging between 0.09 and 0.22 points in the score (from 0 to 5). Motility is unfavorably affected by increasing recent inbreeding but the impact is very small. Runs of homozygosity and metafounders allow us to accurately estimate inbreeding depression and detect recent inbreeding . 653 $aBASCO-BÉARNAISE SHEEP 653 $aINBREEDING DEPRESSION 653 $aMETAFOUNDER 653 $aRUNS OF HOMOZYGOSITY (ROH) 653 $aSEMEN TRAIT 653 $aSHEEP BREEDING 700 1 $aRODRÍGUEZ-RAMILO, S.T. 700 1 $aAGUILAR, I. 700 1 $aASTRUC, J.M. 700 1 $aLEGARRA, A. 700 1 $aVITEZICA, Z. G. 773 $tJournal of Dairy Science, 2021, volume 104, number 3, pages 3221-3230. doi: https://doi.org/10.3168/jds.2020-18761
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128. | | CIAPPESONI, G.; GIMENO, D.; RAVAGNOLO, O.; DE BARBIERI, I.; AGUILAR, I.; MONTOSSI, F.; GRATTAROLA, M. Evaluación genética preliminar del Núcleo Fundacional Merino Fino: análisis combinado población Merino fino - generación 2003. ln: INIA Tacuarembó. Sociedad Criadores Merino Australiano del Uruguay. SUL. Proyecto Merino Fino del Uruguay: quinta distribución de carneros generados en el núcleo fundacional de merino fino de la Unidad Experimental Glencoe, INIA Tacuarembó, 1999 - 2004. Glencoe, Paysandú, 10 diciembre, 2004. Tacuarembó (Uruguay): INIA, 2004. p. 69-83 (INIA Serie Actividades de Difusión ; 392)Biblioteca(s): INIA Tacuarembó. |
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130. | | MISZTAL, I.; TSURUTA, S.; AGUILAR, I.; LEGARRA, A.; VAN RADEN, P.M.; LAWLOR, T.J. Methods to approximate reliabilities in single-step genomic evaluation. Journal of Dairy Science, 2013, v.96, no.1, p.647-654. OPEN ACCESS. Article history: Received April 24, 2012. / Accepted September 18, 2012.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 1 |
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131. | | AGUILAR, I.; MISZTAL, I.; JOHNSON, D.L.; LEGARRA, A.; TSURUTA, S.; LAWLOR, T.J. Hot topic: A unified approach to utilize phenotypic, full pedigree, and genomic information for genetic evaluation of Holstein final score. Journal of Dairy Science, 2010, v. 93, no. 2, p. 743-752. OPEN ACCESS Article history: Received September 14, 2009 / Accepted November 10, 2009 / Published in issue: February 2010.Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 1 |
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132. | | MISZTAL, I.; LOURENCO, D.; TSURUTA, S.; AGUILAR, I.; MASUDA, Y.; BERMANN, M.; CESARANI, A.; LEGARRA, A. How ssGBLUP became suitable for national dairy cattle evaluations. [668]. Part 37 - Bovine dairy - genetic evaluation methods. In: Proceedings of the World Congress on Genetics Applied to Livestock Production (WCGALP), 12., Rotterdam, the Netherlands, 3-8 July 2022. doi: https://doi.org/10.3920/978-90-8686-940-4_668 2757-2760. Article history: Published online: February 9, 2023 -- Corresponding author: I. Misztal, email: ignacy@uga.eduTipo: Trabajos en Congresos/Conferencias |
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134. | | TSURUTA, S.; AGUILAR, I.; MISZTAL, I.; LEGARRA, A.; LAWLOR, T. J. Multiple trait genetic evaluation of linear type traits using genomic and phenotypic data in US Holsteins. Volume Genetic improvement programmes: Selection using molecular information - Poster Sessions, 0489. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 9., Leipzig, Germany, August 1-6, 2010. p. 0489.Tipo: Trabajos en Congresos/Conferencias |
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136. | | MACEDO, F.; NAVAJAS, E.; AGUILAR, I.; GRASSO, A.; PIERUCCIONI, F.; CIAPPESONI, G. New parentage testing SNP panel for commercial breeds will be a useful tool for conservation of creole sheep. Volume Genetic Improvement Programs: Selection for harsh environments and management of animal genetic resources (Posters), , 441. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p. 441. 3 p.Tipo: Trabajos en Congresos/Conferencias |
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139. | | LADO, B.; VÁZQUEZ, D.; QUINCKE, M.; SILVA, P.; AGUILAR, I.; GUTIÉRREZ, L. Resource allocation optimization with multi-trait genomic prediction for bread wheat (Triticum aestivum L.) baking quality. [Original article]. Theoretical and Applied Genetics, 1 December 2018, Volume 131, Issue 12, pp. 2719-2731. OPEN ACCESS. Article history: Received: 29 January 2018 / Accepted: 10 September 2018 / Published online: 19 September 2018.
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Acknowledgements: We express our appreciation for the effort of the technical personnel of INIA La...Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
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