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Registro completo
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Biblioteca (s) : |
INIA Treinta y Tres. |
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Fecha : |
08/01/2021 |
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Actualizado : |
02/09/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
ANTONIOS, S.; RODRÍGUEZ-RAMILO, S.T.; AGUILAR, I.; ASTRUC, J.M.; LEGARRA, A.; VITEZICA, Z. G. |
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Afiliación : |
S. ANTONIOS, GenPhySE, INPT, INRAE, ENVTG, Tolosan, France; S. T. RODRÍGUEZ-RAMILO, GenPhySE, INPT, INRAE, ENVTG, Tolosan, France; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; J.M. ASTRUC, Institut de I'Elevage, Paris, France.; A. LEGARRA, GenPhySE, INPT, INRAE, ENVTG, Tolosan, France; Z. G. VITEZICA, GenPhySE, INPT, INRAE, ENVTG, Tolosan, France. |
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Título : |
Genomic and pedigree estimation of inbreeding depression for semen traits in the Basco-Béarnaise dairy sheep breed. |
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Fecha de publicación : |
2021 |
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Fuente / Imprenta : |
Journal of Dairy Science, 2021, volume 104, number 3, pages 3221-3230. doi: https://doi.org/10.3168/jds.2020-18761 |
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DOI : |
10.3168/jds.2020-18761 |
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Idioma : |
Inglés |
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Notas : |
Article history: Receibed: April 21, 2020 / Accepted: October 5, 2020 /First Publication: 23 Decembrer 2020.
Corresponding author: zulma.viterica@inrae.fr |
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Contenido : |
Abstract
Inbreeding depression is associated with a decrease in performance and fitness of the animals. The goal of this study was to evaluate pedigree-based and genomic methods to estimate the level of inbreeding and inbreeding depression for 3 semen traits (volume, concentration, and motility score) in the Basco-Béarnaise sheep breed. Data comprised 16,196 (or 15,071)
phenotypic records from 620 rams (of which 533 rams had genotypes of 36,464 SNPs). The pedigree included 8,266 animals, composed of the 620 rams and their ancestors. The number of equivalent complete generations for the 620 rams was 7.04. Inbreeding coefficients were estimated using genomic and pedigree-based information. Genomic inbreeding coefficients were estimated from individual SNP and using segments of homozygous SNP (runs of homozygosity, ROH). Short ROH are of old origin, whereas long ROH are due to recent
inbreeding. Considering that the equivalent number of generations in Basco-Béarnaise was 6, inbreeding coefficients for ROH with a length >4 Mb refer to all (recent + old) inbreeding, those with a length >17 Mb correspond to recent inbreeding, and the difference between them indicates old inbreeding. Pedigree-based inbreeding coefficients were also estimated classically, or accounting for nonzero relationships for unknown parents, or including metafounder relationships (estimated using markers) to account for missing pedigree
information. Finally, inbreeding coefficients combining genotyped and nongenotyped animal information were computed from matrix H of the single-step approach, also including metafounders. Inbreeding depression was estimated differently depending on the approach used to compute inbreeding coefficients. These 8 estimators of inbreeding coefficients were included as covariates in different animal models. No inbreeding depression was detected for sperm volume or sperm concentration.
Inbreeding depression was significant for the motility of spermatozoa. The effect of old and recent inbreeding on motility was null and negative, respectively, demonstrating the existence of purging by selection of deleterious recessive alleles affecting motility. A 10% increase in inbreeding would result in a reduction in mean motility ranging between 0.09 and 0.22 points in the score (from 0 to 5). Motility is unfavorably affected by increasing recent inbreeding but the impact is very small. Runs of homozygosity and metafounders allow us to accurately estimate inbreeding depression and detect recent inbreeding . MenosAbstract
Inbreeding depression is associated with a decrease in performance and fitness of the animals. The goal of this study was to evaluate pedigree-based and genomic methods to estimate the level of inbreeding and inbreeding depression for 3 semen traits (volume, concentration, and motility score) in the Basco-Béarnaise sheep breed. Data comprised 16,196 (or 15,071)
phenotypic records from 620 rams (of which 533 rams had genotypes of 36,464 SNPs). The pedigree included 8,266 animals, composed of the 620 rams and their ancestors. The number of equivalent complete generations for the 620 rams was 7.04. Inbreeding coefficients were estimated using genomic and pedigree-based information. Genomic inbreeding coefficients were estimated from individual SNP and using segments of homozygous SNP (runs of homozygosity, ROH). Short ROH are of old origin, whereas long ROH are due to recent
inbreeding. Considering that the equivalent number of generations in Basco-Béarnaise was 6, inbreeding coefficients for ROH with a length >4 Mb refer to all (recent + old) inbreeding, those with a length >17 Mb correspond to recent inbreeding, and the difference between them indicates old inbreeding. Pedigree-based inbreeding coefficients were also estimated classically, or accounting for nonzero relationships for unknown parents, or including metafounder relationships (estimated using markers) to account for missing pedigree
information. Finally, inbreeding coefficients combining genotyped and non... Presentar Todo |
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Palabras claves : |
BASCO-BÉARNAISE SHEEP; INBREEDING DEPRESSION; METAFOUNDER; RUNS OF HOMOZYGOSITY (ROH); SEMEN TRAIT; SHEEP BREEDING. |
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Asunto categoría : |
L10 Genética y mejoramiento animal |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16655/1/Journal-Dairy-Science-2021-Antonios.pdf
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Marc : |
LEADER 03588naa a2200277 a 4500
001 1061660
005 2022-09-02
008 2021 bl uuuu u00u1 u #d
024 7 $a10.3168/jds.2020-18761$2DOI
100 1 $aANTONIOS, S.
245 $aGenomic and pedigree estimation of inbreeding depression for semen traits in the Basco-Béarnaise dairy sheep breed.$h[electronic resource]
260 $c2021
500 $aArticle history: Receibed: April 21, 2020 / Accepted: October 5, 2020 /First Publication: 23 Decembrer 2020. Corresponding author: zulma.viterica@inrae.fr
520 $aAbstract Inbreeding depression is associated with a decrease in performance and fitness of the animals. The goal of this study was to evaluate pedigree-based and genomic methods to estimate the level of inbreeding and inbreeding depression for 3 semen traits (volume, concentration, and motility score) in the Basco-Béarnaise sheep breed. Data comprised 16,196 (or 15,071) phenotypic records from 620 rams (of which 533 rams had genotypes of 36,464 SNPs). The pedigree included 8,266 animals, composed of the 620 rams and their ancestors. The number of equivalent complete generations for the 620 rams was 7.04. Inbreeding coefficients were estimated using genomic and pedigree-based information. Genomic inbreeding coefficients were estimated from individual SNP and using segments of homozygous SNP (runs of homozygosity, ROH). Short ROH are of old origin, whereas long ROH are due to recent inbreeding. Considering that the equivalent number of generations in Basco-Béarnaise was 6, inbreeding coefficients for ROH with a length >4 Mb refer to all (recent + old) inbreeding, those with a length >17 Mb correspond to recent inbreeding, and the difference between them indicates old inbreeding. Pedigree-based inbreeding coefficients were also estimated classically, or accounting for nonzero relationships for unknown parents, or including metafounder relationships (estimated using markers) to account for missing pedigree information. Finally, inbreeding coefficients combining genotyped and nongenotyped animal information were computed from matrix H of the single-step approach, also including metafounders. Inbreeding depression was estimated differently depending on the approach used to compute inbreeding coefficients. These 8 estimators of inbreeding coefficients were included as covariates in different animal models. No inbreeding depression was detected for sperm volume or sperm concentration. Inbreeding depression was significant for the motility of spermatozoa. The effect of old and recent inbreeding on motility was null and negative, respectively, demonstrating the existence of purging by selection of deleterious recessive alleles affecting motility. A 10% increase in inbreeding would result in a reduction in mean motility ranging between 0.09 and 0.22 points in the score (from 0 to 5). Motility is unfavorably affected by increasing recent inbreeding but the impact is very small. Runs of homozygosity and metafounders allow us to accurately estimate inbreeding depression and detect recent inbreeding .
653 $aBASCO-BÉARNAISE SHEEP
653 $aINBREEDING DEPRESSION
653 $aMETAFOUNDER
653 $aRUNS OF HOMOZYGOSITY (ROH)
653 $aSEMEN TRAIT
653 $aSHEEP BREEDING
700 1 $aRODRÍGUEZ-RAMILO, S.T.
700 1 $aAGUILAR, I.
700 1 $aASTRUC, J.M.
700 1 $aLEGARRA, A.
700 1 $aVITEZICA, Z. G.
773 $tJournal of Dairy Science, 2021, volume 104, number 3, pages 3221-3230. doi: https://doi.org/10.3168/jds.2020-18761
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Registro original : |
INIA Treinta y Tres (TT) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas; INIA Tacuarembó. |
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Fecha actual : |
15/07/2015 |
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Actualizado : |
21/10/2019 |
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Tipo de producción científica : |
Revista INIA |
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Autor : |
INIA (INSTITUTO NACIONAL DE INVESTIGACIÓN AGROPECUARIA) |
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Título : |
Revista INIA Uruguay. (No.27, Diciembre 2011). |
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Fecha de publicación : |
2011 |
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Fuente / Imprenta : |
Montevideo (Uruguay): INIA, 2011. |
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Páginas : |
60 p. |
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Serie : |
(Revista INIA; 27) |
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ISSN : |
1510-9011 |
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Idioma : |
Español |
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Thesagro : |
ARROZ; BIOTECNOLOGIA; BOVINOS DE CARNE; CAMBIO CLIMÁTICO; CIENCIA; CITRUS; CLIMA; CLIMATOLOGIA; COMUNICACIÓN; CONTOL DE ENFERMEDADES; CULTIVOS DE GRANO; CULTIVOS DE SECANO; ENTOMOLOGIA; ESPECIES FORRAJERAS; EUCALYPTUS; EXPLOTACION AGRICOLA FAMILIAR; FITOPATOLOGÍA; FORESTALES; FORRAJES; FRUTALES; FRUTICULTURA; GANADO BOVINO; GRANOS; GRAS; HORTALIZAS; HORTICULTURA; INIA; INNOVACION; INVESTIGACIÓN; LECHERÍA; LEGUMINOSAS FORRAJERAS; MANEJO DEL CULTIVO; MEJORAMIENTO ANIMAL; METEOROLOGIA; MICROBIOLOGÍA; OVINOS; PASTURAS; PRODUCCIÓN ANIMAL; PRODUCCION DE LANA; PRODUCCION DE LECHE; PRODUCCION LECHERA; REVISTA INIA 2011; SEMILLAS; SOJA; SUELOS; SUINOS; SUSTENTABILIDAD AMBIENTAL; TECNOLOGÍA; TRANSFERENCIA DE TECNOLOGIA; VARIEDADES; VITICULTURA. |
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Asunto categoría : |
A50 Investigación agraria |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/4837/1/revista-INIA-27.pdf
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Marc : |
LEADER 01908nam a2200745 a 4500
001 1053088
005 2019-10-21
008 2011 bl uuuu u00u1 u #d
022 $a1510-9011
100 1 $aINIA (INSTITUTO NACIONAL DE INVESTIGACIÓN AGROPECUARIA)
245 $aRevista INIA Uruguay. (No.27, Diciembre 2011).
260 $aMontevideo (Uruguay): INIA$c2011
300 $a60 p.
490 $a(Revista INIA; 27)
650 $aARROZ
650 $aBIOTECNOLOGIA
650 $aBOVINOS DE CARNE
650 $aCAMBIO CLIMÁTICO
650 $aCIENCIA
650 $aCITRUS
650 $aCLIMA
650 $aCLIMATOLOGIA
650 $aCOMUNICACIÓN
650 $aCONTOL DE ENFERMEDADES
650 $aCULTIVOS DE GRANO
650 $aCULTIVOS DE SECANO
650 $aENTOMOLOGIA
650 $aESPECIES FORRAJERAS
650 $aEUCALYPTUS
650 $aEXPLOTACION AGRICOLA FAMILIAR
650 $aFITOPATOLOGÍA
650 $aFORESTALES
650 $aFORRAJES
650 $aFRUTALES
650 $aFRUTICULTURA
650 $aGANADO BOVINO
650 $aGRANOS
650 $aGRAS
650 $aHORTALIZAS
650 $aHORTICULTURA
650 $aINIA
650 $aINNOVACION
650 $aINVESTIGACIÓN
650 $aLECHERÍA
650 $aLEGUMINOSAS FORRAJERAS
650 $aMANEJO DEL CULTIVO
650 $aMEJORAMIENTO ANIMAL
650 $aMETEOROLOGIA
650 $aMICROBIOLOGÍA
650 $aOVINOS
650 $aPASTURAS
650 $aPRODUCCIÓN ANIMAL
650 $aPRODUCCION DE LANA
650 $aPRODUCCION DE LECHE
650 $aPRODUCCION LECHERA
650 $aREVISTA INIA 2011
650 $aSEMILLAS
650 $aSOJA
650 $aSUELOS
650 $aSUINOS
650 $aSUSTENTABILIDAD AMBIENTAL
650 $aTECNOLOGÍA
650 $aTRANSFERENCIA DE TECNOLOGIA
650 $aVARIEDADES
650 $aVITICULTURA
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INIA Las Brujas (LB) |
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