02345naa a2200301 a 450000100080000000500110000800800410001902200140006002400370007410000150011124501470012626000090027350002810028252010910056365300110165465300250166565300560169065300210174665300240176765300120179170000160180370000280181970000170184770000190186470000150188370000170189877301280191510646142024-04-24       2024    bl uuuu     u00u1 u    #d  a2405-93907 a10.1016/j.vprsr.2024.1010272DOI1 aPARODI, P.  aMolecular survey of Piroplasmida, Hepatozoon spp. and Anaplasmataceae in anemic and thrombocytopenic dogs from Uruguay.h[electronic resource]  c2024  aArticle history: Received 28 February 2024, Revised 8 April 2024, Accepted 17 April 2024, Available online 21 April 2024, Version of Record 23 April 2024. -- Corresponding author at: Rivera 1350, CP 50000 Salto, Uruguay. E-mail address: jvenzal@unorte.edu.uy (J.M. Venzal). --  aABSTRACT.- Canine tick-borne diseases, such as babesiosis, rangeliosis, hepatozoonosis, anaplasmosis and ehrlichiosis, are of veterinarian relevance, causing mild or severe clinical cases that can lead to the death of the dog. The aim of this study was detecting tick-borne protozoan and rickettsial infections in dogs with anemia and/or thrombocytopenia in Uruguay. A total of 803 domestic dogs were evaluated, and 10% were found positive (detected by PCR) at least for one hemoparasite. Sequence analysis confirmed the presence of four hemoprotozoan species: Rangelia vitalii, Babesia vogeli, Hepatozoon canis and Hepatozoon americanum, and the rickettsial Anaplasma platys. The most detected hemoparasite was R. vitalii, followed by H. canis and A. platys. This is the first report of B. vogeli in Uruguay and the second report of H. americanum in dogs from South America. The results highlight the importance for veterinarians to include hemoparasitic diseases in their differential diagnosis of agents causing anemia and thrombocytopenia. © 2024 Elsevier B.V. All rights reserved.  aAnemia  aCanine hemoparasites  aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA  aThrombocytopenia  aTick-borne diseases  aUruguay1 aBAZZANO, V.1 aARMÚA-FERNÁNDEZ, M.T.1 aFÉLIX, M.L.1 aCARVALHO, L.A.1 aFREIRE, J.1 aVENZAL, J.M.  tVeterinary Parasitology: Regional Studies and Reports. 2024, Volume 51, 101027. https://doi.org/10.1016/j.vprsr.2024.101027