02135naa a2200289 a 450000100080000000500110000800800410001902200140006002400390007410000210011324501270013426000090026150006720027052005770094265300140151965300170153365300180155065300130156865300560158165300220163770000210165970000180168070000180169870000160171670000200173277300930175210645052024-03-20       2024    bl uuuu     u00u1 u    #d  a0041-01017 a10.1016/j.toxicon.2024.1076662DOI1 aMACÊDO, I.L. DE  aFatal Africanized bee attack in captive non-human primates (Saimiri ustus and Sapajus libidinosus).h[electronic resource]  c2024  aArticle history: Received 8 February 2024, Revised 26 February 2024, Accepted 27 February 2024, Available online 28 February 2024, Version of Record 8 March 2024. -- Correspondence: Castro, M.B.D.; Veterinary Pathology and Forensic Laboratory, Veterinary Teaching Hospital, University of Brasilia, Distrito Federal, Brazil; email:mbcastro@unb.br --Funding: This research was partly financed by the Coordination for the Improvement of Higher Education Personnel - Brazil (CAPES) - Finance Code 001 (ILM, DERS). We thank the National Council for Scientific and Technological Development ( CNPq ) for the Research Productivity grant (PQ), process n. 307909/2021-2 (MBC).  aABSTRACT.- Bee stings (BS) are a life-threatening issue and a growing concern for public health and animals in the Americas. We describe the clinical, pathological, and ultrastructural findings of a massive lethal bee attack in two non-human primates (NHPs). Both animals showed BS scattered throughout the skin, surrounded by a local reaction, diffuse pulmonary congestion, edema, hemorrhage, and remarkable degeneration and necrosis of renal epithelial cells from the proximal and distal tubules, characterizing a systemic bee envenomation reaction. © 2024 Elsevier Ltd  aBee venom  aEnvenomation  aKidney injury  aMacaques  aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA  aSystemic reaction1 aSOUSA, D.E.R. DE1 aSOUZA, A.D.R.1 aARMIÉN, A.G.1 aMACHADO, M.1 aCASTRO, M.B. DE  tToxicon. 2024, Volume 241, Article 107666. https://doi.org/10.1016/j.toxicon.2024.107666