02284naa a2200289 a 450000100080000000500110000800800410001902200140006002400460007410000180012024501150013826000090025350004340026252009470069665300170164365300100166065300200167065300290169070000150171970000180173470000150175270000190176770000180178670000160180470000160182077301580183610631502022-05-18       2021    bl uuuu     u00u1 u    #d  a1983-02467 a10.24070/bjvp.1983-0246.v14i2p99-1012DOI1 aLIBOREIRO, M.  aSpontaneous outbreak of Pascalia glauca poisoning in sheep in Argentina. (Case Report).h[electronic resource]  c2021  aArticle history: Submitted 29 December 2020; Accepted 22 April 2021. Corresponding author: Cantón, G.; Instituto Nacional de Tecnología Agropecuaria (INTA), Ruta Nacional 226 km. 73.5, Balcarce, Argentina; email:canton.german@inta.gob.ar  --  This study was financially supported in part by Red Nacional de Laboratorios de Diagnóstico Veterinario (RIST. I111; INTA, Argentina) and Innovaciones Tecnológicas Agropecuarias S.A.  aABSTRACT.- Pascalia glauca is a native weed and one of the most common hepatotoxic plant affecting cattle in Argentina. Although experimental P. glauca poisoning have been reported in sheep, no spontaneous cases have been reported in this species. This work describes an outbreak of intoxication after spontaneous consumption of P. glauca, affecting 20% (6/30) sheep of a commercial flock. Affected sheep were ataxic, depressive, with mucous nasal discharge, cough and abdominal breathing. During post mortem examination, liver was swollen and a diffuse enhancement of the reticular pattern (?nutmeg liver?) was visible. Histopathological examination reveals severe and extensive acute diffuse centrilobular hepatic necrosis with hemorrhage. The presence of the toxic plant, the clinical and pathological findings allows us to confirm the etiology of this outbreak. © 2021, Brazilian Association of Veterinary Pathology. All rights reserved.  aIntoxication  aOvine  aPascalia glauca  aPLATAFORMA SALUD ANINMAL1 aFLORES, C.1 aARMENDANO, J.1 aSCHILD, C.1 aFERNÁNDEZ, E.1 aODRIOZOLA, E.1 aMORRELL, E.1 aCANTÓN, G.  tBrazilian Journal of Veterinary Pathology, 2021, Volume 14, Issue 2, Pages 99-101. OPEN ACCESS. doi: https://doi.org/10.24070/bjvp.1983-0246.v14i2p99-101