02796naa a2200289 a 450000100080000000500110000800800410001902200140006002400360007410000170011024501590012726000090028650001450029552017150044065300260215565300170218165300280219865300220222665300220224865300270227070000180229770000150231570000180233070000200234870000140236877301240238210606572020-01-21       2019    bl uuuu     u00u1 u    #d  a1517-83827 a10.1007/s42770-019-00151-w2DOI1 aCASAUX, M.L.  aAntibiotic resistance in Salmonella enterica isolated from dairy calves in Uruguay. (Veterinary Microbiology - Short Communication)h[electronic resource]  c2019  aArticle history: Received: 22 January 2019 / Accepted: 4 September 2019. The online version of this article contains supplementary material.  aABSTRACT. Salmonella enterica is an important animal and human pathogen that can cause enteritis and septicaemia in calves. Generally, antibiotics are prescribed for the treatment of salmonellosis in dairy calves. Here, we report the isolation of antibiotic resistant S. enterica serotypes from calves, including multidrug-resistant isolates. A total of 544 faecal samples from live healthy and diarrheic dairy calves from 29 commercial dairy farms and organ samples from 19 deceased calves that succumbed to salmonellosis in 12 commercial dairy farms in Uruguay were processed for selective S. enterica culture. In total, 41 isolates were serotyped, and susceptibility to 14 antibiotics, from 9 classes of compounds, was evaluated by disk-diffusion test. The minimum inhibitory concentration (MIC) was determined by microdilution. Salmonella Typhimurium was the most frequent serotype, followed by S. Dublin and S. Anatum. Whether determined by diffusion assay or microdilution, resistance to tetracycline, streptomycin and ampicillin were the most frequently pattern found. Based on MIC, 5 isolates were resistant to at least one antibiotic, 21 were resistant to 2 antibiotics, and 14 were multidrug-resistant (resistant to at least one antibiotic in 3 different categories of antibiotics). Eleven different resistance patterns were found. Multidrug resistance in S. enterica is a concern for animal and public health not only because of its zoonotic potential but also due to the possibility of transfer resistance determinants to other bacterial genera. This represents the first report of the antibiotic resistance in S. enterica in dairy farms in Uruguay.  © 2019, Sociedade Brasileira de Microbiologia.  aAntibiotic resistance  aDairy calves  aPLATAFORMA SALUD ANIMAL  aSalmonella Anatum  aSalmonella Dublin  aSalmonella Typhimurium1 aCAFFARENA, D.1 aSCHILD, C.1 aGIANNITTI, F.1 aRIET-CORREA, F.1 aFRAGA, M.  tBrazilian Journal of Microbiology, 1 October 2019, Volume 50, Issue 4, Pages 1139-1144. Doi: 10.1007/s42770-019-00151-w