02927naa a2200385 a 450000100080000000500110000800800410001902400340006010000180009424501210011226000090023350001030024252017260034565000120207165000330208365000130211665300310212965300310216065300110219165300230220265300210222565300180224665300280226465300180229265300200231070000150233070000150234570000160236070000150237670000190239170000140241070000180242470000200244277300790246210582272019-10-23       2018    bl uuuu     u00u1 u    #d7 a10.1177/10406387177426212DOI1 aCAFFARENA, D.  aNatural lymphatic (atypical) actinobacillosis in cattle caused by Actinobacillus lignieresii.h[electronic resource]  c2018  aArticle History: Article first published online: December 4, 2017; Issue published: March 1, 2018.  aAbstract. Bovine actinobacillosis is typically characterized by pyogranulomatous glossitis (wooden tongue). The involvement of other tissues, generally the skin or lymph nodes, has been regarded as atypical or cutaneous. We describe herein 2 outbreaks of actinobacillosis affecting primarily the lymph nodes of the head and neck. The disease affected 40 of 540 lactating cows in a dairy herd, and 5 of 335 two-y-old steers in a beef herd. Multiple or single, occasionally ulcerated nodules were observed in the region of the mandible, neck, and shoulder, including the parotid, submandibular, retropharyngeal, and prescapular lymph nodes. The histologic lesions were multifocal pyogranulomatous lymphadenitis, dermatitis, and cellulitis with Splendore?Hoeppli material. One steer had an exophytic pyogranuloma in the gingiva and another died because of ruminal tympany secondary to oropharyngeal and esophageal obstruction by a pyogranulomatous mass. Actinobacillus lignieresii was isolated from the lesions and identified by amplification, sequencing, and analysis of the 16S ribosomal (r)DNA gene. Seven of 8 cows recovered after treatment with sodium iodide. Lymphatic actinobacillosis is a frequent disease in Uruguay, southern Brazil, and Argentina. Morbidity is 1?50%; mortality is <1%. A. lignieresii apparently penetrates the intact oral and pharyngeal mucosa, infecting primarily the regional lymph nodes. Later, lesions may extend to the subcutaneous tissue and the skin, causing ulceration. Affected cattle with draining pyogranulomas contaminate the environment, favoring disease transmission, and should be treated with sodium iodide or antibiotics and isolated from the herd in order to control the disease.  aBOVINOS  aENFERMEDADES DE LOS ANIMALES  aNOVILLOS  aACTINOBACILLUS LIGNIERESII  aACTINOBACILOSIS LINFÁTICA  aBOVINE  aDRAINING ABSCESSES  aLENGUA DE MADERA  aLYMPHADENITIS  aPLATAFORMA SALUD ANIMAL  aPYOGRANULOMAS  aVACAS LACTANTES1 aRABAZA, A.1 aCASAUX, L.1 aMACÍAS, M.1 aSCHILD, C.1 aMONESIGLIO, C.1 aFRAGA, M.1 aGIANNITTI, F.1 aRIET-CORREA, F.  tJournal of Veterinary Diagnostic Investigationgv.30, n.2,p.218-225, 2018.