02089naa a2200313 a 450000100080000000500110000800800410001902400390006010000170009924501380011626000090025450001550026352010450041865000110146365000330147465000130150765300170152065300240153765300200156165300180158170000180159970000190161770000200163670000260165670000190168270000200170170000170172177300370173810566712017-02-17       2017    bl uuuu     u00u1 u    #d7 a10.1016/j.toxicon.2016.11.2582DOI1 aSANTOS, D.S.  aShort communicationbPrimary photosensitization caused by ingestion of Froelichia humboldtiana by dairy goats.h[electronic resource]  c2017  aArticle history: Received 9 October 2016 / Received in revised form / 22 November 2016 / Accepted 23 November 2016 / Available online 24 November 2016  aABSTRACT.  This study aimed to describe the first report of an outbreak of primary photosensitization in dairy goats caused by Froelichia humboldtiana. The disease occurred from March to May 2014, in a mixed flock of 15 Saanen, Alpine, and crossbred lactating goats. The entire flock was affected; however, the Saanen and cross-bred goats developed more severe lesions, and their milk production decreased by as much as 75%. Lesions were progressive and consisted of skin hyperemia, edema, and necrosis, especially in depigmented areas. An experimental study with two goats resulted in photodermatitis, similar to that observed in the natural cases, 10?14 days after the beginning of plant ingestion. Serum activities of aspartate aminotransferase (AST) and -glutamyltransferase (GGT) and, direct, indirect, and total bilirubin serum concentrations were within the normal ranges. In conclusion, F. humboldtiana causes primary photosensitization in goats with a negative impact on milk production.  © 2016 Elsevier Ltd. All rights reserved.  aCABRAS  aENFERMEDADES DE LOS ANIMALES  aNECROSIS  aGOAT DISEASE  aLOW MILK PRODUCTION  aPHOTODERMATITIS  aSKIN NECROSIS1 aSILVA, C.B.C.1 aARAÚJO, V. O.1 aSOUZA, M. DE F.1 aLACERDA-LUCENA, P. B.1 aSIMOES, S.V.D.1 aRIET-CORREA, F.1 aLUCENA, R.B.  tToxicon, 2017gv. 125, p. 65-69.