02621naa a2200325 a 450000100080000000500110000800800410001902400380006010000210009824501620011926000090028150001110029052015830040165000210198465000230200565000220202865000130205065300190206365300110208265300220209365300090211565300130212470000240213770000170216170000130217870000150219170000180220670000190222477300520224310521322019-10-11       2014    bl uuuu     u00u1 u    #d7 a10.1016/j.livsci.2014.10.0082DOI1 aASTESSIANO, A.L.  aMetabolic and endocrine profiles and hepatic gene expression in periparturient, grazing primiparous cows with different body reserves.h[electronic resource]  c2014  aArticle history: received 12 April 2014; received in revised form 3 October 2014; accepted 6 October 2014.  aAbstract The objective was to determine effects of prepartum BCS on metabolic/endocrine profiles and hepatic gene expression and their associations with cow and calf performance in grazing suckled-primiparous beef cows from 49 to 49 days postpartum (DPP). Twenty crossbred cows selected according to expected calving date, were classified at 35 DPP into thin (BCSo4.5) or moderate (BCSZ4.5) BCS groups and blocked by calving date. Blood samples were obtained weekly for metabolite and hormone analyses and liver biopsies were collected at 11, 7, 31, and 49 DPP. Cow BW and BCS were greater in moderate than thin cows throughout the period. Estimated energy intake was greater in moderate than thin cows Moderate BCS cows produced more milk than thin cows at 35 DPP and calves from moderate BCS cows had greater BW and average daily gain than calves from thin cows. Serum leptin tended to be greater while adiponectin was less in moderate than thin BCS cows. Overall serum insulin was less in moderate than thin cows while serum IGF-I during the prepartum was greater in moderate than thin BCS cows. Growth hormone receptor (GHR) mRNA was 2-fold greater at 11 DPP while GHR1A and IGF1 mRNA were 2.5-fold less at 49 DPP in moderate than thin BCS cows. The IGFBP2 mRNA decreased in moderate but increased in thin BCS cows from 11 to 49 DPP. These results were associated with changes in body reserves during prepartum and may indicate that prepartum differences in BCS lost can affect nutrient partitioning towards the mammary gland, and subsequent milk production and calf weight.  aBOVINOS DE CARNE  aCONDICION CORPORAL  aNUTRICIÓN ANIMAL  aPASTOREO  aBODY CONDITION  aCATTLE  aMETABOLIC PROFILE  aMRNA  aPASTURES1 aPÉREZ-CLARIGET, R.1 aQUINTANS, G.1 aSOCA, A.1 aMEIKLE, A.1 aCROOKER, B.A.1 aCARRIQUIRY, M.  tLivestock Science, 2014gv.170, no. 1, p. 63-71