02625naa a2200301 a 450000100080000000500110000800800410001902400290006010000170008924501630010626000090026952017230027865000100200165300220201165300120203365300190204565300200206465300170208465300170210165300140211865300220213270000220215470000160217670000150219270000150220770000150222277300860223710441102019-10-08       2006    bl uuuu     u00u1 u    #d7 a10.1051/rnd:20060242DOI1 aBANCHERO, G.  aEndocrine and metabolic factors involved in the effect of nutrition on the production of colostrum in female sheep. (Conference Paper).h[electronic resource]  c2006  aAbstract- We investigated the physiological relationship between diet during pregnancy and colostrum production in ewes to test the hypothesis that for ewes that are in low body condition, with low fat reserves, the food supply will be the main source of energy for colostrum synthesis. To this end, we measured the amount of colostrum accumulated by ewes under two levels of nutrition. We also measured the circulating concentrations of metabolites and hormones associated with lactogenesis (beta-hydroxybutyrate, glucose, progesterone, prolactin, cortisol, growth hormone, leptin, insulin and insulin-like growth factor-I) Ewes were either under-fed at 70 (n = 15) or well-fed at 110% (n = 10) of their daily metabolisable energy requirement during the last two months of pregnancy. Colostrum accumulation up to parturition was 168 +/-48 g for under-fed ewes and 451 +/-103 g for well-fed ewes. After birth, under-fed ewes produced less colostrum than well-fed ewes but the difference was no longer significant. The level of nutrition also influenced the plasma concentrations of hormones and metabolites related to lactogenesis. Progesterone concentrations decreased before lambing in all animals but in under-fed ewes the fall appeared to be too small to initiate the onset of colostrum production. Beta-hydroxybutyrate concentrations were higher in under-fed than in well-fed ewes, suggesting that the under-fed ewes were mobilising more adipose tissue but they still did not meet their ME requirements for colostrum production. We concluded that, in underfed ewes, there are insufficient nutrients for adequate lactation and the hormone regime is inappropriate for good udder development and colostrum synthesis.  aOVEJA  aCALOSTRO EN OVEJA  aGLUCOSE  aGROWTH HORMONE  aHYDROXYBUTYRATE  aLACTOGENESIS  aPROGESTERONE  aPROLACTIN  aUDDER DEVELOPMENT1 aPEREZ CLARIGET, R1 aBENCINI, R.1 aLINDSAY,D.1 aMILTON, J.1 aMARTIN, G.  tReproduction Nutrition Development, July 2006, Volume 46, Issue 4, Pages 447-460.