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| 1. |  | SALINAS, L.M.; BALSEIRO, A.; JIRÓN, W.; PERALTA, A.; MUÑÓZ, D.; FAJARDO, J.; GAYO, E.; MARTÍNEZ, I.Z.; RIET-CORREA, F.; GARDNER, D.R.; GARCÍA MARÍN, J.F. Neurological syndrome in goats associated with Ipomoea trifida and Ipomoea carnea containing calystegines. Toxicon, January 2019, Volume 157, Pages 8-11. Article history: Received 16 September 2018 // Received in revised form 7 November 2018 // Accepted 9 November 2018 // Available online 14 November 2018.
This work was partially supported by a grant from Instituto Nacional de...| Biblioteca(s): INIA Las Brujas. |
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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
28/11/2018 |
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Actualizado : |
28/11/2018 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
SALINAS, L.M.; BALSEIRO, A.; JIRÓN, W.; PERALTA, A.; MUÑÓZ, D.; FAJARDO, J.; GAYO, E.; MARTÍNEZ, I.Z.; RIET-CORREA, F.; GARDNER, D.R.; GARCÍA MARÍN, J.F. |
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Afiliación : |
LUIS MANUEL SALINAS, Universidad Internacional Antonio de Valdivieso (UNIAV), Rivas, Nicaragua; Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain.; ANA BALSEIRO, Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Centro de Biotecnología Animal, Gijón, Asturias, Spain.; WILLIAM JIRÓN, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; ANA PERALTA, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; DAVID MUÑÓZ, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; JORGE FAJARDO, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; ELENA GAYO, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain.; ILEANA ZORHAYA MARTÍNEZ, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain; Universidad Popular Autónoma del Estado de Puebla (UPAEP), Mexico.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DALE R. GARDNER, Poisonous Plant Research Laboratory, Logan, UT, United States.; JUAN FRANCISCO GARCÍA MARÍN, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain. |
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Título : |
Neurological syndrome in goats associated with Ipomoea trifida and Ipomoea carnea containing calystegines. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
Toxicon, January 2019, Volume 157, Pages 8-11. |
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ISSN : |
0041-0101 |
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DOI : |
10.1016/j.toxicon.2018.11.291 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 16 September 2018 // Received in revised form 7 November 2018 // Accepted 9 November 2018 // Available online 14 November 2018.
This work was partially supported by a grant from Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria ( INIA , Spain), reference number E-RTA2013-00013-C04-04 (FEDER co-funded). |
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Contenido : |
ABSTRACT.
A disease characterized by ataxia, tremors and nystagmus had been observed in goats in Nicaragua. The main histologic lesions were loss and neuronal vacuolation of Purkinje cells and Wallerian-like degeneration mainly in the cerebellum, suggesting a glycoprotein storage disease. Ipomoea carnea and Ipomoea trifida found in the paddocks were negative for swainsonine, but contained calystegines at 0.02% and 0.06% suggesting that the disease was caused by these substances, which are competitive inhibitors of β-glucosidase and α-galactosidase activities.
© 2018 Elsevier Ltd |
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Palabras claves : |
CALYSTEGINES; GOAT; IPOMOEA CARNEA; IPOMOEA TRIFIDA; NICARAGUA; POISONING. |
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Asunto categoría : |
-- |
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Marc : |
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100 1 $aSALINAS, L.M.
245 $aNeurological syndrome in goats associated with Ipomoea trifida and Ipomoea carnea containing calystegines.$h[electronic resource]
260 $c2018
500 $aArticle history: Received 16 September 2018 // Received in revised form 7 November 2018 // Accepted 9 November 2018 // Available online 14 November 2018. This work was partially supported by a grant from Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria ( INIA , Spain), reference number E-RTA2013-00013-C04-04 (FEDER co-funded).
520 $aABSTRACT. A disease characterized by ataxia, tremors and nystagmus had been observed in goats in Nicaragua. The main histologic lesions were loss and neuronal vacuolation of Purkinje cells and Wallerian-like degeneration mainly in the cerebellum, suggesting a glycoprotein storage disease. Ipomoea carnea and Ipomoea trifida found in the paddocks were negative for swainsonine, but contained calystegines at 0.02% and 0.06% suggesting that the disease was caused by these substances, which are competitive inhibitors of β-glucosidase and α-galactosidase activities. © 2018 Elsevier Ltd
653 $aCALYSTEGINES
653 $aGOAT
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653 $aIPOMOEA TRIFIDA
653 $aNICARAGUA
653 $aPOISONING
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773 $tToxicon, January 2019, Volume 157, Pages 8-11.
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