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| 1. |  | SILVEIRA, A. M.; MOREIRA, E. C.; VAZ, F.; LORENZO, C. DE; DRIEMEIER, D.; FURLAN, F.; DANTAS, A. F. M.; RIET-CORREA, F. Encefalopatia hepática secundária à intoxicação por Tephrosia cinerea em ovinos.(Hepatic encephalopathy secondary to poisoning by Tephrosia cinerea in sheep). Pesquisa Veterinária Brasileira, Rio de Janeiro v. 38, n. 4, p. 635-641, 2018. Article History: Recebido em 28 de abril de 2017.//Aceito para publicação em 17 de maio de 2017.| Biblioteca(s): INIA La Estanzuela. |
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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha actual : |
22/06/2018 |
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Actualizado : |
09/10/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
SILVEIRA, A. M.; MOREIRA, E. C.; VAZ, F.; LORENZO, C. DE; DRIEMEIER, D.; FURLAN, F.; DANTAS, A. F. M.; RIET-CORREA, F. |
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Afiliación : |
ALINE M. SILVEIRA, Hospital Veterinário/Universidade Federal de Campina Grande, Brasil.; ÉDIPO C. MOREIRA, Hospital Veterinário/Universidade Federal de Campina Grande - UFCG, Brasil.; FERNANDO VAZ, Hospital Veterinário/Universidade Federal de Campina Grande - UFCG, Brasil.; CÍNTIA DE LORENZO, Setor de Patologia Veterinária/Hospital Veterinário/Universidade Federal do Rio Grande do Sul - UFRGS, Brasil.; DAVID DRIEMEIER, Setor de Patologia Veterinária/Hospital Veterinário/Universidade Federal do Rio Grande do Sul- UFRGS, Brasil.; FERNANDO FURLAN, Universidade Federal de Mato Grosso - UFMT, Brasil.; ANTONIO F. M. DANTAS, Hospital Veterinário/Universidade Federal de Campina Grande - UFCG, Brasil.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay./Universidade Federal de Campina Grande - UFCG, Brasil. |
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Título : |
Encefalopatia hepática secundária à intoxicação por Tephrosia cinerea em ovinos.(Hepatic encephalopathy secondary to poisoning by Tephrosia cinerea in sheep). |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
Pesquisa Veterinária Brasileira, Rio de Janeiro v. 38, n. 4, p. 635-641, 2018. |
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DOI : |
10.1590/1678-5150-PVB-5290 |
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Idioma : |
Portugués |
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Notas : |
Article History: Recebido em 28 de abril de 2017.//Aceito para publicação em 17 de maio de 2017. |
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Contenido : |
Abstracts:
In the semiarid region of northeastern Brazil, Tephrosia cinerea causes periacinar hepatic fibrosis in sheep with severe ascites and, occasionally, nervous signs. Sixteen sheep from six outbreaks of T. cinerea poisoning were studied. All sheep had histologic lesion of periacinar fibrosis and six showed, in the brain, vacuolization (spongy degeneration) of the white matter and junction between grey and white matter and presence of Alzheimer type II astrocytes in the grey matter. The disease was produced experimentally in two sheep, that presented porto-sistemic shunts and similar histologic lesions as those observed in the spontaneous cases. Immunohistochemistry revealed weak labelling with anti-GFAP antibodies suggesting a degenerative alteration of astrocytes with accumulation of dense bodies and reduction of
the GFAP. There was strong labelling with anti-S100 antibodies suggesting cellular reactivity with proliferation of mitochondria and endoplasmatic reticulum. Such alterations are characteristic of the effects caused by ammonia on the astrocytes. It is concluded that in poisoning by T. cinerea nervous signs due to hepatic encephalopathy occur in some sheep. |
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Palabras claves : |
ENCEFALOPATÍA HEPÁTICA; ENVENENAMIENTO DE PLANTAS; PLANTAS HEPATOTÓXICAS; PLANTAS VENENOSAS; PLATAFORMA SALUD ANIMAL. |
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Thesagro : |
NERVOUS SYSTEM DISEASES; OVINOS; PLANT POISONING; PLANTA TOXICAS; POISONOUS PLANTS; SHEEP; TEPHROSIA CINEREA. |
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Asunto categoría : |
L74 Trastornos misceláneos de los animales |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/10456/1/Pesq.-Vet.-Bras.-384p.635-641-2018..pdf
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Marc : |
LEADER 02465naa a2200373 a 4500
001 1058723
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008 2018 bl uuuu u00u1 u #d
024 7 $a10.1590/1678-5150-PVB-5290$2DOI
100 1 $aSILVEIRA, A. M.
245 $aEncefalopatia hepática secundária à intoxicação por Tephrosia cinerea em ovinos.(Hepatic encephalopathy secondary to poisoning by Tephrosia cinerea in sheep).$h[electronic resource]
260 $c2018
500 $aArticle History: Recebido em 28 de abril de 2017.//Aceito para publicação em 17 de maio de 2017.
520 $aAbstracts: In the semiarid region of northeastern Brazil, Tephrosia cinerea causes periacinar hepatic fibrosis in sheep with severe ascites and, occasionally, nervous signs. Sixteen sheep from six outbreaks of T. cinerea poisoning were studied. All sheep had histologic lesion of periacinar fibrosis and six showed, in the brain, vacuolization (spongy degeneration) of the white matter and junction between grey and white matter and presence of Alzheimer type II astrocytes in the grey matter. The disease was produced experimentally in two sheep, that presented porto-sistemic shunts and similar histologic lesions as those observed in the spontaneous cases. Immunohistochemistry revealed weak labelling with anti-GFAP antibodies suggesting a degenerative alteration of astrocytes with accumulation of dense bodies and reduction of the GFAP. There was strong labelling with anti-S100 antibodies suggesting cellular reactivity with proliferation of mitochondria and endoplasmatic reticulum. Such alterations are characteristic of the effects caused by ammonia on the astrocytes. It is concluded that in poisoning by T. cinerea nervous signs due to hepatic encephalopathy occur in some sheep.
650 $aNERVOUS SYSTEM DISEASES
650 $aOVINOS
650 $aPLANT POISONING
650 $aPLANTA TOXICAS
650 $aPOISONOUS PLANTS
650 $aSHEEP
650 $aTEPHROSIA CINEREA
653 $aENCEFALOPATÍA HEPÁTICA
653 $aENVENENAMIENTO DE PLANTAS
653 $aPLANTAS HEPATOTÓXICAS
653 $aPLANTAS VENENOSAS
653 $aPLATAFORMA SALUD ANIMAL
700 1 $aMOREIRA, E. C.
700 1 $aVAZ, F.
700 1 $aLORENZO, C. DE
700 1 $aDRIEMEIER, D.
700 1 $aFURLAN, F.
700 1 $aDANTAS, A. F. M.
700 1 $aRIET-CORREA, F.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 38, n. 4, p. 635-641, 2018.
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