Fecha/hora: 16/06/2024 01:12:38

Biblioteca(s): | INIA Las Brujas.
Fecha corriente: | 11/09/2014
Fecha de la última actualización: | 24/06/2021
Autoria: | MISZTAL, I.; VITEZICA, Z.G.; LEGARRA, A.; AGUILAR, I.; SWAN, A.A.
Afiliación: | IGNACIO AGUILAR GARCIA, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay.
Título: | Unknown-parent groups in single-step genomic evaluation.
Año de publicación: | 2013
Fuente/Imprenta: | Journal of Animal Breeding and Genetics, 2013, v.130, no.4, p.252-258.
ISSN: | 0931-2668
DOI: | http://dx.doi.org/10.1111/jbg.12025
Idioma: | Inglés

Contenido:

SUMMARY:.

In single-step genomic evaluation using best linear unbiased prediction (ssGBLUP), genomic predictions are calculated with a relationship matrix that combines pedigree and genomic information. For missing pedigrees, unknown selection processes, or inclusion of several populations, a BLUP model can include unknown-parent groups (UPG) in the animal effect. For ssGBLUP, UPG equations also involve contributions from genomic relationships. When those contributions are ignored, UPG solutions and genetic predictions can be biased. Options to eliminate or reduce such bias are presented. First, mixed model equations can be modified to include contributions to UPG elements from genomic relationships (greater software complexity). Second, UPG can be implemented as separate effects (higher cost of computing and data processing). Third, contributions can be ignored when they are relatively small, but they may be small only after refinements to UPG definitions. Fourth, contributions may approximately cancel out when genomic and pedigree relationships are constructed for compatibility; however, different construction steps are required for unknown parents from the same or different populations. Finally, an additional polygenic effect that also includes UPG can be added to the model.
© 2013 Blackwell Verlag GmbH.

Palabras-Clave: | BLUP (BEST LINEAR UNBIASED PREDICTION).
Thesagro: | EVALUACIÓN GENÉTICA; GENÉTICA ANIMAL.
Categoría del tema: | L10 Genética y mejoramiento animal
Registro original: | INIA Las Brujas (LB)
Ejemplares: | LB - (100046-1) - PXI - AP - DD - PP/JR.AN.BREED.GENET./2013 -  -  - DIS