Fecha/hora: 03/06/2024 05:14:13

Biblioteca(s): | INIA Las Brujas.
Fecha corriente: | 10/09/2014
Fecha de la última actualización: | 25/11/2019
Autoria: | VAZ, P.; BAKKER, M.G.; SALOMON, C.E.; KINKEL, L.L.
Afiliación: | PATRICIA VAZ JAURI, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay.
Título: | Subinhibitory antibiotic concentrations mediate nutrient use and competition among soil Streptomyces.
Año de publicación: | 2013
Fuente/Imprenta: | PLoS ONE, 2013, v.8, no.12, e81064. OPEN ACCESS.
ISSN: | 1932-6203
DOI: | 10.1371/journal.pone.0081064
Idioma: | Inglés

Contenido:

ABSTRACT.

Though traditionally perceived as weapons, antibiotics are also hypothesized to act as microbial signals in natural habitats. However, while subinhibitory concentrations of antibiotics (SICA) are known to shift bacterial gene expression, specific hypotheses as to how SICA influence the ecology of natural populations are scarce. We explored whether antibiotic ?signals?, or SICA, have the potential to alter nutrient utilization, niche overlap, and competitive species interactions among Streptomyces populations in soil. For nine diverse Streptomyces isolates, we evaluated nutrient utilization patterns on 95
different nutrient sources in the presence and absence of subinhibitory concentrations of five antibiotics. There were significant changes in nutrient use among Streptomyces isolates, including both increases and decreases in the capacity to use individual nutrients in the presence vs. in the absence of SICA. Isolates varied in their responses to SICA and antibiotics varied in their effects on isolates. Furthermore, for some isolate-isolate-antibiotic combinations, competition-free growth (growth for an isolate on all nutrients that were not utilized by a competing isolate), was increased in the presence of SICA, reducing the potential fitness cost of nutrient competition among those competitors. This suggests that antibiotics may provide a mechanism for bacteria to actively minimize niche overlap among competitors in soil. Thus, in contrast to antagonistic coevolutionary dynamics, antibiotics as signals may mediate coevolutionary displacement among coexisting Streptomyces, thereby hindering the emergence of antibiotic resistant phenotypes. These results contribute to our broadunderstanding of the ecology and evolutionary biology of antibiotics and microbial signals in nature. 
© 2013 Vaz Jauri et al.

Thesagro: | MICROORGANISMOS DEL SUELO.
Categoría del tema: | P30 Ciencia del suelo y manejo del suelo
URL: | http://www.ainfo.inia.uy/digital/bitstream/item/3075/1/Vaz-Jauri-P.-2013-PLOS-ONE-v.812-e81064.pdf
Registro original: | INIA Las Brujas (LB)
Ejemplares: | LB - (100041-1) - PXI - AP - DD - PP/PLOS ONE/2014 -  -  - DIS