Fecha/hora: 09/06/2024 22:16:04

Biblioteca(s): 	INIA Las Brujas.	
Tipo de la producción científica: 	Artículos en Revistas Indexadas Internacionales	
Circulación/Nivel: 	Internacional - --	
Fecha corriente: 	06/05/2016	
Fecha de la última actualización: 	23/10/2019	
Autoria: 	MAYA, L.; PUENTES, R.; REOLÓN, E.; ACUÑA, P.; RIET-CORREA, F.; RIVERO, R.; CRISTINA, J.; COLINA, R.	
Afiliación: 	L. MAYA, Laboratorio de Virología Molecular, Regional Norte, CENUR Noroeste, Universidad de la República; R. PUENTES, Área de Inmunología, Facultad de Veterinaria, Universidad de la República; E. REOLÓN, Laboratorios Santa Elena-VIRBAC; P. ACUÑA, Laboratorios Santa Elena-VIRBAC; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; R. RIVERO, DILAVE “Miguel C. Rubino”, Laboratorio Regional Noroeste; J. CRISTINA, Laboratorio de Virología Molecular, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la República; R. COLINA, Laboratorio de Virología Molecular, Regional Norte, CENUR Noroeste, Universidad de la República.	
Título: 	Molecular diversity of bovine viral diarrhea virus in Uruguay.	
Año de publicación: 	2016	
Fuente/Imprenta: 	Archives of Virology, 2016, v.161, no.3, p. 529-535.	
DOI: 	10.1007/s00705-015-2688-4	
Idioma: 	Inglés	
Notas: 	Article history: Received: 1 July 2015 / Accepted: 14 November 2015 / Published online: 23 November 2015	
Contenido: 	ABSTRACT.

Bovine viral diarrhea (BVD) affects bovine production and reproduction causing significant economic losses all over the world. Two viral species has been recognized: BVDV-1 and BVDV-2, both distributed worldwide. Recently, novel specie of BVDV named HoBi-like pestivirus was discovered. The presence of BVDV was confirmed in 1996 in Uruguay, however, does not exist until today a schedule of compulsory vaccination along the country. Serological studies with samples from all Uruguayan herds were performed during 2000 and 2001 demonstrating that all of them were seropositive to BVDV with a mean prevalence of 69 %. In addition, there have been no new studies done since those previously described and it is important to mention that the genetic diversity of BVD has never been described in Uruguay. Nowadays, there is strongly suspect that BVDV is one of the most important causes of reproductive failures in our herds. The aim of this study was to describe for the first time in Uruguay the genetic diversity of BVDV with samples collected from different regions along the country. Serological status of 390 non-vaccinated animals against BVDV with reproductive problems from farms of Rivera, Tacuarembó and Florida departments of Uruguay were studied. All herds were seropositive to BVDV and high proportion of animals were positive (298/390), while 4.1 % (16/390) of the animals were positive to Antigen Capture ELISA test and Real Time PCR. Phylogenetic analysis performed with concatenated sequences from the 5&#8242;UTR and Npro genomic regions revealed that BVDV-1 and BVDV-2 are infecting our herds, being BVDV-1 the most frequently found. The major subtype was BVDV-1a, followed by BVDV-1i and BVDV-2b. This is the first study that describes the genetic diversity of BVDV in Uruguay and it will contribute to the elaboration of sanitization programs.
@ Springer-Verlag Wien 2015	
Palabras-Clave: 	BOVINE VIRAL DIARRHEA (BVD).	
Thesagro: 	ENFERMEDADES DE LOS ANIMALES; VIROLOGIA.	
Categoría del tema: 	--	
Registro original: 	INIA Las Brujas (LB)	
Ejemplares: 	LB - (101002-1) - PXI - AP - DD - PP/ARCH.VIROL./2016 -  -  - DIS