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Biblioteca(s): | INIA Tacuarembó.
Fecha corriente: | 15/12/2017
Fecha de la última actualización: | 27/03/2019
Autoria: | WALLACE, F.; BENNADJI, Z.; FERREIRA, F.; OLIVARO, C.
Afiliación: | FEDERICO WALLACE; ZOHRA BENNADJI SOUALHIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO AMAURY FERREIRA CHIESA; CRISTINA OLIVARO.
Título: | Analysis of an immunoadjuvant saponin fraction from Quillaja brasiliensis leaves by Electrospray Ionization Ion Trap Multiple-Stage Mass Spectrometry. [Resumen de poster].
Año de publicación: | 2017
Fuente/Imprenta: | In: Escola de Espectrometria de Massas, 3., BrMASS, Natal-RN , 03 a 08 de dezembro, 2017.
Idioma: | Español

Contenido:

Saponins are natural surfactant compounds whose aqueous solutions can form stable foam and micellar solutions. They are glycosides formed by one, two or three oligosaccharide chains linked to a steroid or triterpene aglycone through acetal and/or ester-acetal bonds. Quillaja brasiliensis is an endemic tree species in southern
Brazil and northern Uruguay. It has been shown in experimental vaccines in animal models that the aqueous extract and some of the purified saponin fractions obtained from leaves of Q. brasiliensis have immunoadjuvant activity comparable with Quil-A®, the main commercial adjuvant product based on Q. saponaria saponins [1, 2]. These saponins are also able to form ISCOM- type nanometric micellar structures which are even more effective vaccine adjuvants, generating both humoral and
cellular immune responses [2]. The aim of this study was to perform a preliminary structural characterization of the immunoadjuvant fraction of saponins designated as Fraction B.

Palabras-Clave: | QUILLAJA BRASILIENSIS.
Thesagro: | SAPONINAS.
Categoría del tema: | K10 Producción forestal
URL: | http://www.ainfo.inia.uy/digital/bitstream/item/8137/1/Resumen-Poster-2017-Bennadji.pdf
Registro original: | INIA Tacuarembó (TBO)
Ejemplares: | TBO - (102237-1) - PXI - PS - DD -  -  -  - DIS