Fecha/hora: 13/06/2024 07:06:11

Biblioteca(s): 	INIA Las Brujas.	
Fecha corriente: 	28/11/2018	
Fecha de la última actualización: 	28/11/2018	
Autoria: 	SALINAS, L.M.; BALSEIRO, A.; JIRÓN, W.; PERALTA, A.; MUÑÓZ, D.; FAJARDO, J.; GAYO, E.; MARTÍNEZ, I.Z.; RIET-CORREA, F.; GARDNER, D.R.; GARCÍA MARÍN, J.F.	
Afiliación: 	LUIS MANUEL SALINAS, Universidad Internacional Antonio de Valdivieso (UNIAV), Rivas, Nicaragua; Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain.; ANA BALSEIRO, Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Centro de Biotecnología Animal, Gijón, Asturias, Spain.; WILLIAM JIRÓN, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; ANA PERALTA, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; DAVID MUÑÓZ, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; JORGE FAJARDO, Universidad Nacional Autónoma de Nicaragua (UNAN), León, Nicaragua.; ELENA GAYO, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain.; ILEANA ZORHAYA MARTÍNEZ, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain; Universidad Popular Autónoma del Estado de Puebla (UPAEP), Mexico.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DALE R. GARDNER, Poisonous Plant Research Laboratory, Logan, UT, United States.; JUAN FRANCISCO GARCÍA MARÍN, Facultad de Veterinaria, Universidad de León, Campus de Vegazana, León, Spain.	
Título: 	Neurological syndrome in goats associated with Ipomoea trifida and Ipomoea carnea containing calystegines.	
Año de publicación: 	2018	
Fuente/Imprenta: 	Toxicon, January 2019, Volume 157, Pages 8-11.	
ISSN: 	0041-0101	
DOI: 	10.1016/j.toxicon.2018.11.291	
Idioma: 	Inglés	
Notas: 	Article history: Received 16 September 2018 // Received in revised form 7 November 2018 // Accepted 9 November 2018 // Available online 14 November 2018.
This work was partially supported by a grant from Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria ( INIA , Spain), reference number E-RTA2013-00013-C04-04 (FEDER co-funded).	
Contenido: 	ABSTRACT.
A disease characterized by ataxia, tremors and nystagmus had been observed in goats in Nicaragua. The main histologic lesions were loss and neuronal vacuolation of Purkinje cells and Wallerian-like degeneration mainly in the cerebellum, suggesting a glycoprotein storage disease. Ipomoea carnea and Ipomoea trifida found in the paddocks were negative for swainsonine, but contained calystegines at 0.02% and 0.06% suggesting that the disease was caused by these substances, which are competitive inhibitors of &#946;-glucosidase and &#945;-galactosidase activities. 
© 2018 Elsevier Ltd	
Palabras-Clave: 	CALYSTEGINES; GOAT; IPOMOEA CARNEA; IPOMOEA TRIFIDA; NICARAGUA; POISONING.	
Categoría del tema: 	--	
Registro original: 	INIA Las Brujas (LB)	
Ejemplares: 	LB - (101730-1) - PXI - AP - DD - PP/TOXICON/2019 -  -  - DIS