Fecha/hora: 16/06/2024 01:04:33

Biblioteca(s): 	INIA La Estanzuela.	
Fecha corriente: 	02/10/2017	
Fecha de la última actualización: 	05/11/2019	
Autoria: 	ARAÚJO, V.O.DE; OLIVEIRA NETO, T.S; SIMOES, S.V.D; FERREIRA DA SILVA, T.K.; RIET-CORREA, F.; LUCENA , R.B.	
Afiliación: 	VALBER ONOFRE DE ARAÚJO, Postgraduate Program in Animal Science, Universidade Federal da Paraíba, Areia, Paraíba, 58397-000, Brazil.; TEMÍSTOCLES SOARES OLIVEIRA NETO, Veterinary Hospital, Universidade Federal da Paraíba, Areia, Paraíba, 58397-000, Brazil.; SARA VILAR DANTAS SIMOES, Veterinary Hospital, Universidade Federal da Paraíba, Areia, Paraíba, 58397-000, Brazil.; THATYANA KELLY FERREIRA DA SILVA, Veterinary Hospital, Universidade Federal da Paraíba, Areia, Paraíba, 58397-000, Brazil.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay./Postgraduate Program in Animal Science, Universidade Federal da Paraíba, Areia, Paraíba, 58397-000, Brazil.; RICARDO BARBOSA LUCENA, Postgraduate Program in Animal Science, Universidade Federal da Paraíba, Areia, Paraíba, 58397-000, Brazil.	
Título: 	Primary photosensitization and contact dermatitis caused by Malachra fasciata Jacq. N.V. (Malvaceae) in sheep.	
Año de publicación: 	2017	
Fuente/Imprenta: 	Toxicon, 2017 Nov, volumen 138, p.184-187.	
DOI: 	10.1016/j.toxicon.2017.09.009	
Idioma: 	Inglés	
Notas: 	Article history: Received 20 July 2017.//Received in revised form 11 September 2017.//Accepted 11 September 2017 //Available online 14 September 2017	
Contenido: 	Abstract:
Farmers from Paraiba state, Northeast Brazil, claim that Malachra fasciata causes cutaneous lesions in sheep. To test its toxicity the plant was harvested daily and fed ad libitum for 21 days to 3 sheep as the sole food source (# 1?3). An additional sheep (# 4) was maintained as a control. Cutaneous lesions of photosensitization initiated after 7 days and increased continuously over the next 21 days. The dose ingested varied between 129 g/kg to 175 g/kg. Alopecia, hyperemia and crusting were observed in the animals. On day 22, sheep 3 was euthanized. At necropsy, no gross or microscopic alterations were observed in the liver. Skin biopsies were performed in the remaining animals Histopathology of skin of the three sheep included acanthosis, orthokeratosis, and multifocal infiltration by lymphocytes, eosinophils and plasma cells around blood vessels and appendages in the dermis. The Splendore-Hoeppli phenomenon was observed in the dermis of sheep 2, due probably by contact dermatitis. After the end of administration Sheep 1 and 2 were protected from sunlight and the lesions regressed within two weeks. This experiment indicates that M. fasciata causes primary photosensitization and contact dermatitis in sheep.	
Palabras-Clave: 	DERMATITIS; ENVENENAMIENTO; LESIONES DE LA PIEL; PLATAFORMA SALUD ANIMAL; POISONING PLANT; SALUD ANIMAL; SKIN.	
Thesagro: 	PLANTAS TOXICAS.	
Categoría del tema: 	L74 Trastornos misceláneos de los animales	
Registro original: 	INIA La Estanzuela (LE)	
Ejemplares: 	LE - (102220-1) - PXI - AP - DD -  -  -  - DIS