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Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy.
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Biblioteca (s) :  INIA Las Brujas.
Fecha :  21/01/2020
Actualizado :  21/01/2020
Tipo de producción científica :  Artículos en Revistas Indexadas Internacionales
Autor :  DE CARVALHO NUNES, L.; STEGELMEIER, B. L.; COOK, D.; PFISTER, J. A.; GARDNER, D. R.; RIET-CORREA, F.; WEICH, K. D.
Afiliación :  LOUISIANE DE CARVALHO NUNES, Department of Veterinary Science, Federal University of Espírito Santo, Alegre, Espírito Santo, Brazil; BRYAN L. STEGELMEIER, USDA-ARS Poisonous Plant Research Laboratory, USA; DANIEL COOK, USDA-ARS Poisonous Plant Research Laboratory, USA; JAMES A. PFISTER, USDA-ARS Poisonous Plant Research Laboratory, USA; DALE R. GARDNER, USDA-ARS Poisonous Plant Research Laboratory, USA; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Veterinary Hospital, Center for Health and Rural Technology, Patos Campus, Federal University of Campina Grande, Brazil; KEVIN D. WELCH, USDA-ARS Poisonous Plant Research Laboratory, USA.
Título :  Clinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats.
Fecha de publicación :  2019
Fuente / Imprenta :  Toxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016
ISSN :  0041-0101
DOI :  10.1016/j.toxicon.2019.09.016
Idioma :  Inglés
Notas :  Article history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019.
Contenido :  ABSTRACT. The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic a... Presentar Todo
Palabras claves :  Astragalus; Calystegines; Ipomoea; Locoweed; PLATAFORMA SALUD ANIMAL; Swainsonine.
Asunto categoría :  A50 Investigación agraria
Marc :  Presentar Marc Completo
Registro original :  INIA Las Brujas (LB)
Biblioteca Identificación Origen Tipo / Formato Clasificación Cutter Registro Volumen Estado
LB102097 - 1PXIAP - DDPP/TOXICON/2019

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1.Imagen marcada / sin marcar COOK, D.; OLIVEIRA,C.A.; GARDNER, D.R.; PFISTER, J.A; RIET-CORREA, G; RIET-CORREA, F. Changes in swainsonine, calystegine, and nitrogen concentrations on an annual basis in Ipomoea carnea. Toxicon, v. 95, p. 62 - 66, 2015. Article history: Received 31 October 2014.//Received in revised form 31 December 2014.//Accepted 3 January 2015.//Available online 5 January 2015.
Tipo: Artículos en Revistas Indexadas InternacionalesCirculación / Nivel : A - 1
Biblioteca(s): INIA La Estanzuela.
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2.Imagen marcada / sin marcar DE CARVALHO NUNES, L.; STEGELMEIER, B. L.; COOK, D.; PFISTER, J. A.; GARDNER, D. R.; RIET-CORREA, F.; WEICH, K. D. Clinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats. Toxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016 Article history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019.
Tipo: Artículos en Revistas Indexadas InternacionalesCirculación / Nivel : Internacional - --
Biblioteca(s): INIA Las Brujas.
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3.Imagen marcada / sin marcar NASCIMENTO, N.C.F.; AIRES, L.D.A.; PFISTER, J.A.; MEDEIROS, R.M.T.; RIET-CORREA, F.; MENDONÇA, F.S. Plantas cardiotóxicas para ruminantes no Brasil. [Cardiotoxic plants affecting ruminants in Brazil.] Pesquisa Veterinária Brasileira v.38 ,n.7. p. 1239-1249, July 2018. OPEN ACCESS. Article history: Recebido em 21 de agosto de 2017. // Aceito para publicação em 28 de agosto de 2017.
Tipo: Artículos en Revistas Indexadas InternacionalesCirculación / Nivel : Internacional - --
Biblioteca(s): INIA La Estanzuela.
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4.Imagen marcada / sin marcar ALMEIDA, W. M.; ROCHA, B. P.; PFISTER, J. A.; MEDEIROS, R. M. T.; RIET-CORREA, F.; CHAVES, H. A. S.; SILVA FILHO, G. B.; MENDONÇA, F. S. Spontaneous poisoning by Prosopis juliflora (Leguminosae) in sheep. Pesquisa Veterinária Brasileira, Brasilia, v. 37, n. 2, p. 110-114, 2017. OPEN ACCESS. Article history: Recieved on september 8, 2015.// Accepted for publication on August 25, 2016.
Tipo: Artículos en Revistas Indexadas InternacionalesCirculación / Nivel : Internacional - --
Biblioteca(s): INIA La Estanzuela.
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5.Imagen marcada / sin marcar RIET-CORREA, F.; MEDEIROS, R. M. T.; PFISTER, J. A.; MENDONÇA, F. S. Toxic plants affecting the nervous system of ruminants and horses in Brazil. (Plantas tóxicas que afetam o sistema nervoso de ruminantes e equinos no Brasil). Pesquisa Veterinária Brasileira, Brasília, DF v. 37, n. 12, p. 1357-1368, dezembro. 2017. Article history: Received 11 May 2017 // Accepted 14 May 2017
Tipo: Artículos en Revistas Indexadas InternacionalesCirculación / Nivel : Internacional - --
Biblioteca(s): INIA La Estanzuela.
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Registros recuperados : 5
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