Fecha/hora: 26/07/2024 21:59:40

Biblioteca(s): 	INIA La Estanzuela.	
Fecha corriente: 	11/07/2017	
Fecha de la última actualización: 	30/01/2020	
Autoria: 	SOUSA, R.F.A.; ALMEIDA, V.M.; NETO, J.E.; NASCIMENTO, C.W.A.; MEDEIROS, G.X.; MEDEIROS, R.M.T.; RIET-CORREA, F.; MENDONÇA, F.S.	
Afiliación: 	R. F. A. SOUSA, Programa de Pós-Graduação em Ciência Veterinária, Universidade Federal Rural de Pernambuco, Brasil.; V.M. ALMEIDA, Programa de Pós-Graduação em Ciência Veterinária, Universidade Federal Rural de Pernambuco, Brasil; J. E. NETO, Programa de Pós-Graduação em Ciência Veterinária, Universidade Federal Rural de Pernambuco, Brasil; C W A NASCIMENTO, Departamento de Agronomia, Universidade Federal Rural de Pernambuco, Recife, Pernambuco, Brazil.; G. X. MEDEIROS, Hospital Veterinario, CSTR, Patos, Brazil.; R. M. T. MEDEIROS, Hospital Veterinario, CSTR, Patos, Brazil.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; F.S. MENDONÇA, Laboratorio de Diagnostico Animal, DMFA/UFRPE, Recife, Pernambuco, Brasil.	
Título: 	Laryngeal neuropathy in adult goats with copper deficiency.	
Año de publicación: 	2017	
Fuente/Imprenta: 	Veterinary Pathology, 2017, v. 54, n.4., p.676-682.	
DOI: 	10.1177/0300985816681410	
Idioma: 	Inglés	
Notas: 	Article history: Article first published online: December 14, 2016.//Issue published: July 1, 2017.	
Contenido: 	Abstract:
The aim of this study was to elucidate the cause of a neurological syndrome characterized by stridor in adult goats with clinical
signs of copper deficiency. The main clinical signs consisted of apathy, emaciation, pale mucous membranes, mucous nasal discharge,
dyspnea, severe achromotrichia, diffuse alopecia, torpor, ataxia, and stridor. When the goats were forced to move, the
stridor increased. In a herd of 194 Toggenburg goats, 10 adult goats with clinical signs of copper deficiency were removed from
the herd and divided into 2 groups: group 1, which consisted of 4 nannies and 1 buck with stridor, and group 2, which consisted of
4 nannies and 1 buck without stridor. Group 3, used as a control, consisted of 5 adult goats from another flock without any clinical
signs of disease. The mean serum copper concentrations were 1.3 + 0.3 mmol/L in group 1, 8.1 + 1.1 mmol/L in group 2, and
11.3 + 2.2 mmol/L in group 3. The mean serum iron concentrations were 42.3 + 14.2 mmol/L in group 1, 39.1 + 8.2 mmol/L in
group 2, and 20.6+ 6.1 mmol/L in group 3. The main histological lesions in goats from group 1 were axonal degeneration of the
recurrent laryngeal nerves and atrophy of the muscles of vocal folds and of the dorsal cricoarytenoid and right and left cricothyroid
muscles. Goats with ataxia had neuronal degeneration and necrosis of cerebellar Purkinje cells and of the cranial
cervical ganglion. We concluded that the stridor was caused by axonal degeneration of the recurrent laryngeal nerves due to the
severe copper deficiency.	
Palabras-Clave: 	COOPER DEFICIENCY; DEFICIENCIA DE COBRE; DEFICIENCIA DE HIERRO; IRON; LARYNGEAL; MUSCLE; NERVOUS SYSTEM; PARALISIS; PARALYSIS; RUMINANTS; SISTEMA NERVIOSO; SNORING DISEASE; STRIDOR.	
Thesagro: 	OVEJAS; RUMIANTES.	
Categoría del tema: 	E16 Enfermedades de los animales	
Registro original: 	INIA La Estanzuela (LE)	
Ejemplares: 	LE - (102142-1) - PXI - AP - DD -  -  -  - DIS