Fecha/hora: 20/05/2024 14:42:07

Biblioteca(s): 	INIA La Estanzuela.	
Fecha corriente: 	20/06/2022	
Fecha de la última actualización: 	20/06/2022	
Autoria: 	UZAL, F.A.; GIANNITTI, F.; ASIN, J.	
Afiliación: 	FRANCISCO A. UZAL, California Animal Health and Food Safety, University of California-Davis, San Bernardino, CA 92408, USA.; FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JAVIER ASIN, California Animal Health and Food Safety, University of California-Davis, San Bernardino, CA 92408, USA.	
Título: 	Yellow Lamb Disease (Clostridium perfringens Type A Enterotoxemia of Sheep): A Review.	
Año de publicación: 	2022	
Fuente/Imprenta: 	Animals 2022, 12, 1590. Open Access. Doi: https://doi.org/10.3390/ani12121590	
Idioma: 	Inglés	
Notas: 	Article history:Received: 12 May 2022 / Revised: 16 June 2022 / Accepted: 16 June 2022 / Published: 20 June 2022.	
Contenido: 	bstract: Yellow lamb disease is an infrequent disease in sheep for which there is scant literature, and that has been reported in the US, Australia, New Zealand, South Africa and Europe, although anecdotal evidence indicates that it may have also been diagnosed in South America. The disease is produced by some strains of Clostridium perfringens type A that produce unusually high levels of alpha- toxin. Because C. perfringens type A is ubiquitous and is found in the intestine of most clinically healthy sheep, diagnosis of yellow lamb disease is challenging and requires quantitating the amount of this microorganism present in feces and/or intestinal content. Clinically, yellow lamb disease is characterized by depression, anemia, icterus and hemoglobinuria. Occasionally, sudden death may occur. Gross findings include generalized icterus, red urine in the bladder, enlarged, pale, and friable spleen, enlarged liver with an acinar pattern, and dark, swollen kidneys. Microscopically,
yellow lamb disease is characterized by centrilobular necrosis of the liver, hemoglobinuria-associated acute tubular injury, splenic congestion, pulmonary congestion and edema. Although there are no vaccines specifically designed to prevent yellow lamb disease, several vaccines against the different types of C. perfringens may afford at least some level of protection against yellow lamb disease.	
Palabras-Clave: 	Alpha toxin; Clostridium perfringens type A; Icterus; PLATAFORMA DE SALUD ANIMAL; Yellow lamb disease.	
Categoría del tema: 	L73 Enfermedades de los animales	
URL: 	http://www.ainfo.inia.uy/digital/bitstream/item/16524/1/animals-12-01590.pdf	
Registro original: 	INIA La Estanzuela (LE)	
Ejemplares: 	LE - (103583-1) - PXI - AP - DD - PP/Animals/2022 -  -  - DIS