Fecha/hora: 11/06/2024 09:48:13

Biblioteca(s): 	INIA La Estanzuela.	
Fecha corriente: 	15/04/2021	
Fecha de la última actualización: 	02/09/2022	
Autoria: 	RABAZA, A.; FRAGA, M.; CORBELLINI, L.G.; TURNER, K.M.E.; RIET-CORREA, F.; EISLER, M.C.	
Afiliación: 	ANA VIRGINIA RABAZA MARTINEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay./ Bristol Veterinary School, University of Bristol, Langford House, Langford, Bristol BS40 5DU, UK .; MARTIN FRAGA COTELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; LUIS GUSTAVO CORBELLINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; KATY M.E. TURNER, Bristol Veterinary School, University of Bristol, Langford House, Langford, Bristol BS40 5DU, UK.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MARK C. EISLER, Bristol Veterinary School, University of Bristol, Langford House, Langford, Bristol BS40 5DU, UK.	
Título: 	Molecular prevalence of Coxiella burnetii in bulk-tank milk from bovine dairy herds: Systematic review and meta-analysis. (Review).	
Año de publicación: 	2021	
Fuente/Imprenta: 	One Health, 2021, Volume 12, Article number 100208. OPEN ACCESS. Doi: https://doi.org/10.1016/j.onehlt.2020.100208	
DOI: 	10.1016/j.onehlt.2020.100208	
Idioma: 	Inglés	
Notas: 	Article history: Received 29 September 2020 / Revised 21 December 2020/ Accepted 21 December 2020/ Available online 24 December 2020. Corresponding author: E-mail address: mark.eisler@bristol.ac.uk (M.C. Eisler).  The first author is supported by a PhD scholarship 
A. Rabaza et al. One Health 12 (2021) 1002088(POS_EXT_2015_1_123804) from Agencia Nacional de Innovacion  e Investigacion  (ANII), Uruguay.	
Contenido: 	Abstract:
Coxiella burnetii is an obligate intracellular zoonotic bacterium that causes Q fever. Ruminants, including cattle, are broadly known to be reservoirs for this bacterium. Since 2006, many research groups have evaluated the herd-level prevalence of C. burnetii in cattle by molecular techniques on composite milk samples. This study explored the global C. burnetii herd-level prevalence from studies done on bovine bulk-tank milk (BTM) samples using PCR-based analysis. Also, moderators were investigated to identify sources of heterogeneity. Databases (CAB Abstracts, Medline via Ovid, PubMed, Web of Science and Google Scholar) were searched for index articles on C. burnetii prevalence in BTM samples by PCR published between January-1973 and November-2018. Numerous studies (1054) were initially identified, from which seventeen original publications were included in the meta-analysis based on the pre-defined selection criteria. These studies comprised 4031 BTM samples from twelve countries. A random-effects model was used because of considerable heterogeneity (I2 = 98%) to estimate the herd-level prevalence of C. burnetii as 37.0%(CI95%25.2?49.5%). The average herd size appeared to account for a high level of the heterogeneity. No other moderators (geographic location, gross national income or notification criteria for Q fever) seemed to be determinant. This systematic evaluation demonstrated a high molecular prevalence of C. burnetii in BTM samples both in European and non-European countries, evidencing a widespread herd-level circulation of this agent in bovine dairy farms around the world. Meta-regression showed herd size as the most relevant moderator with the odds of a BTM sample testing positive doubling with every unit increase.	
Palabras-Clave: 	COXIELLOSIS; IS1111; META-PREVALENCE; PCR; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL; PLATAFORMA DE SALUD ANIMAL; Q FEVER.	
Categoría del tema: 	E16 Enfermedades de los animales	
URL: 	http://www.ainfo.inia.uy/digital/bitstream/item/16678/1/1-s2.0-S2352771420303098-main.pdf
https://www.sciencedirect.com/science/article/pii/S2352771420303098/pdfft?md5=e267cbec15aa46066b75fcf51935f399&pid=1-s2.0-S2352771420303098-main.pdf	
Registro original: 	INIA La Estanzuela (LE)	
Ejemplares: 	LE - (103313-1) - PXI - AP - DD - PP/One Health/ 2021 -  -  - DIS